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Select item 112146251.

Inter-cell type interactions that control JNK signaling in the Drosophila intestine

Peng Zhang, Stephen M. Pronovost, Marco Marchetti, Chenge Zhang, Xiaoyu Kang, Tahmineh Kandelouei, Christopher Li, Bruce A. Edgar

Nat Commun. 2024; 15: 5493. Published online 2024 Jun 28. doi: 10.1038/s41467-024-49786-w

PMCID:: PMC11214625

Abstract Article PDF–8.9M

Select item 109627592.

A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins

Annabel Guichard, Shenzhao Lu, Oguz Kanca, Daniel Bressan, Yan Huang, Mengqi Ma, Sara Sanz Juste, Jonathan C. Andrews, Kristy L. Jay, Marketta Sneider, Ruth Schwartz, Mei-Chu Huang, Danqing Bei, Hongling Pan, Liwen Ma, Wen-Wen Lin, Ankush Auradkar, Pranjali Bhagwat, Soo Park, Kenneth H. Wan, Takashi Ohsako, Toshiyuki Takano-Shimizu, Susan E. Celniker, Michael F. Wangler, Shinya Yamamoto, Hugo J. Bellen, Ethan Bier

Cell Rep. Author manuscript; available in PMC 2024 Mar 25.

Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112842. Published online 2023 Jul 20. doi: 10.1016/j.celrep.2023.112842

PMCID:: PMC10962759

Abstract Article PDF–3.0M

Select item 109274993.

Interplay between autophagy and CncC regulates dendrite pruning in Drosophila

Jue Yu Kelly Tan, Liang Yuh Chew, Gábor Juhász, Fengwei Yu

Proc Natl Acad Sci U S A. 2024 Mar 5; 121(10): e2310740121. Published online 2024 Feb 26. doi: 10.1073/pnas.2310740121

PMCID:: PMC10927499

Abstract Article PDF–3.5M

Select item 104998104.

Gut barrier defects, intestinal immune hyperactivation and enhanced lipid catabolism drive lethality in NGLY1-deficient Drosophila

Ashutosh Pandey, Antonio Galeone, Seung Yeop Han, Benjamin A. Story, Gaia Consonni, William F. Mueller, Lars M. Steinmetz, Thomas Vaccari, Hamed Jafar-Nejad

Nat Commun. 2023; 14: 5667. Published online 2023 Sep 13. doi: 10.1038/s41467-023-40910-w

PMCID:: PMC10499810

Abstract Article PDF–7.5M

Select item 92396805.

An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination

Oguz Kanca, Jonathan Zirin, Yanhui Hu, Burak Tepe, Debdeep Dutta, Wen-Wen Lin, Liwen Ma, Ming Ge, Zhongyuan Zuo, Lu-Ping Liu, Robert W Levis, Norbert Perrimon, Hugo J Bellen

eLife. 2022; 11: e76077. Published online 2022 Jun 20. doi: 10.7554/eLife.76077

PMCID:: PMC9239680

Abstract Article PDF–1.2M

Select item 91623396.

An in vivo drug repurposing screen and transcriptional analyses reveals the serotonin pathway and GSK3 as major therapeutic targets for NGLY1 deficiency

Kevin A. Hope, Alexys R. Berman, Randall T. Peterson, Clement Y. Chow

PLoS Genet. 2022 Jun; 18(6): e1010228. Published online 2022 Jun 2. doi: 10.1371/journal.pgen.1010228

PMCID:: PMC9162339

Abstract Article PDF–2.6M

Select item 90050527.

Tracing the NGLY1 footprints: insights from Drosophila

Ashutosh Pandey, Hamed Jafar-Nejad

J Biochem. 2022 Feb; 171(2): 153–160. Published online 2021 Jul 16. doi: 10.1093/jb/mvab084

PMCID:: PMC9005052

Abstract Article PDF–743K

Select item 89591748.

Cytosolic O-GlcNAcylation and PNG1 maintain Drosophila gut homeostasis by regulating proliferation and apoptosis

Hyun-jin Na, Lara K. Abramowitz, John A. Hanover

PLoS Genet. 2022 Mar; 18(3): e1010128. Published online 2022 Mar 16. doi: 10.1371/journal.pgen.1010128

PMCID:: PMC8959174

Abstract Article PDF–5.7M

Select item 84688279.

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders

Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D’Avino, Maria Grazia Giansanti

Cells. 2021 Sep; 10(9): 2336. Published online 2021 Sep 6. doi: 10.3390/cells10092336

PMCID:: PMC8468827

Abstract Article PDF–4.1M

Select item 776962110.

A conserved role for AMP-activated protein kinase in NGLY1 deficiency

Seung Yeop Han, Ashutosh Pandey, Tereza Moore, Antonio Galeone, Lita Duraine, Tina M. Cowan, Hamed Jafar-Nejad

PLoS Genet. 2020 Dec; 16(12): e1009258. Published online 2020 Dec 14. doi: 10.1371/journal.pgen.1009258

PMCID:: PMC7769621

Abstract Article PDF–3.7M

Select item 775805911.

A Drosophila screen identifies NKCC1 as a modifier of NGLY1 deficiency

Dana M Talsness, Katie G Owings, Emily Coelho, Gaelle Mercenne, John M Pleinis, Raghavendran Partha, Kevin A Hope, Aamir R Zuberi, Nathan L Clark, Cathleen M Lutz, Aylin R Rodan, Clement Y Chow

eLife. 2020; 9: e57831. Published online 2020 Dec 14. doi: 10.7554/eLife.57831

PMCID:: PMC7758059

Abstract Article PDF–1.1M

Select item 739454412.

Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation

Antonio Galeone, Joshua M Adams, Shinya Matsuda, Maximiliano F Presa, Ashutosh Pandey, Seung Yeop Han, Yuriko Tachida, Hiroto Hirayama, Thomas Vaccari, Tadashi Suzuki, Cathleen M Lutz, Markus Affolter, Aamir Zuberi, Hamed Jafar-Nejad

eLife. 2020; 9: e55596. Published online 2020 Jul 28. doi: 10.7554/eLife.55596

PMCID:: PMC7394544

Abstract Article PDF–9.4M

Select item 696157813.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 602789714.

Defects in the Neuroendocrine Axis Contribute to Global Development Delay in a Drosophila Model of NGLY1 Deficiency

Tamy Portillo Rodriguez, Joshua D. Mast, Tom Hartl, Tom Lee, Peter Sand, Ethan O. Perlstein

G3 (Bethesda) 2018 Jul; 8(7): 2193–2204. Published online 2018 May 7. doi: 10.1534/g3.118.300578

Correction in:: G3 (Bethesda). 2019 Jan; 9(1): 315.

PMCID:: PMC6027897

Abstract Article PDF–2.3M

Select item 588622015.

Transcriptome and functional analysis in a Drosophila model of NGLY1 deficiency provides insight into therapeutic approaches

Katie G Owings, Joshua B Lowry, Yiling Bi, Matthew Might, Clement Y Chow

Hum Mol Genet. 2018 Mar 15; 27(6): 1055–1066. Published online 2018 Jan 15. doi: 10.1093/hmg/ddy026

PMCID:: PMC5886220

Abstract Article PDF–532K

Select item 583206516.

highroad Is a Carboxypetidase Induced by Retinoids to Clear Mutant Rhodopsin-1 in Drosophila Retinitis Pigmentosa Models

Huai-Wei Huang, Brian Brown, Jaehoon Chung, Pedro M. Domingos, Hyung Don Ryoo

Cell Rep. Author manuscript; available in PMC 2018 Mar 1.

Published in final edited form as: Cell Rep. 2018 Feb 6; 22(6): 1384–1391. doi: 10.1016/j.celrep.2018.01.032

PMCID:: PMC5832065

Abstract Article PDF–1.4M

Select item 570780517.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900218.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 559923119.

Tissue-specific regulation of BMP signaling by Drosophila N-glycanase 1

Antonio Galeone, Seung Yeop Han, Chengcheng Huang, Akira Hosomi, Tadashi Suzuki, Hamed Jafar-Nejad

eLife. 2017; 6: e27612. Published online 2017 Aug 4. doi: 10.7554/eLife.27612

PMCID:: PMC5599231

Abstract Article PDF–9.5M

Select item 480554520.

A genome-wide resource for the analysis of protein localisation in Drosophila

Mihail Sarov, Christiane Barz, Helena Jambor, Marco Y Hein, Christopher Schmied, Dana Suchold, Bettina Stender, Stephan Janosch, Vinay Vikas KJ, RT Krishnan, Aishwarya Krishnamoorthy, Irene RS Ferreira, Radoslaw K Ejsmont, Katja Finkl, Susanne Hasse, Philipp Kämpfer, Nicole Plewka, Elisabeth Vinis, Siegfried Schloissnig, Elisabeth Knust, Volker Hartenstein, Matthias Mann, Mani Ramaswami, K VijayRaghavan, Pavel Tomancak, Frank Schnorrer

eLife. 2016; 5: e12068. Published online 2016 Feb 20. doi: 10.7554/eLife.12068

PMCID:: PMC4805545

Abstract Article PDF–9.1M

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