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Select item 99868171.

METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m⁶A homeostasis

Zhan‐Cheng Zeng, Qi Pan, Yu‐Meng Sun, Heng‐Jing Huang, Xiao‐Tong Chen, Tian‐Qi Chen, Bo He, Hua Ye, Shun‐Xin Zhu, Ke‐Jia Pu, Ke Fang, Wei Huang, Yue‐Qin Chen, Wen‐Tao Wang

EMBO Rep. 2023 Mar; 24(3): e55762. Published online 2023 Jan 4. doi: 10.15252/embr.202255762

PMCID:: PMC9986817

Abstract Article PDF–3.5M

Select item 89566042.

CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity

Julia Joung, Paul C. Kirchgatterer, Ankita Singh, Jang H. Cho, Suchita P. Nety, Rebecca C. Larson, Rhiannon K. Macrae, Rebecca Deasy, Yuen-Yi Tseng, Marcela V. Maus, Feng Zhang

Nat Commun. 2022; 13: 1606. Published online 2022 Mar 25. doi: 10.1038/s41467-022-29205-8

PMCID:: PMC8956604

Abstract Article PDF–3.9M

Select item 67372303.

Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant

Ana M. Matos, Francisco R. Pinto, Patrícia Barros, Margarida D. Amaral, Rainer Pepperkok, Paulo Matos

J Biol Chem. 2019 Sep 6; 294(36): 13396–13410. Published online 2019 Jul 19. doi: 10.1074/jbc.RA119.008738

PMCID:: PMC6737230

Abstract Article PDF–2.6M

Select item 59873154.

Low-Copy Number Polymorphism in DEFA1/DEFA3 Is Associated with Susceptibility to Hospital-Acquired Infections in Critically Ill Patients

Jialian Zhao, Qiang Gu, Lifeng Wang, Weize Xu, Lihua Chu, Ya Wang, Zhongwang Li, Shuijing Wu, Jianguo Xu, Zhiyong Hu, Qiang Shu, Xiangming Fang

Mediators Inflamm. 2018; 2018: 2152650. Published online 2018 May 22. doi: 10.1155/2018/2152650

PMCID:: PMC5987315

Abstract Article PDF–788K

Select item 53958835.

PPBP and DEFA1/DEFA3 genes in hyperlipidaemia as feasible synergistic inflammatory biomarkers for coronary heart disease

Yaowapa Maneerat, Kriengchai Prasongsukarn, Surachet Benjathummarak, Wilanee Dechkhajorn

Lipids Health Dis. 2017; 16: 80. Published online 2017 Apr 19. doi: 10.1186/s12944-017-0471-0

PMCID:: PMC5395883

Abstract Article PDF–1.6M

Select item 49855816.

Elevated Plasma α-Defensins (HNP1–3) Levels Correlated with IgA1 Glycosylation and Susceptibility to IgA Nephropathy

Yuan-yuan Qi, Xu-jie Zhou, Fa-juan Cheng, Hong Zhang

Dis Markers. 2016; 2016: 8123138. Published online 2016 Aug 2. doi: 10.1155/2016/8123138

PMCID:: PMC4985581

Abstract Article PDF–666K

Select item 49373557.

Human neutrophil peptides inhibit cleavage of von Willebrand factor by ADAMTS13: a potential link of inflammation to TTP

Vikram G. Pillai, Jialing Bao, Catherine B. Zander, Jenny K. McDaniel, Palaniappan S. Chetty, Steven H. Seeholzer, Khalil Bdeir, Douglas B. Cines, X. Long Zheng

Blood. 2016 Jul 7; 128(1): 110–119. Prepublished online 2016 May 13. doi: 10.1182/blood-2015-12-688747

PMCID:: PMC4937355

Abstract Article

Select item 41128988.

Relevance of α-defensins (HNP1-3) and defensin β-1 in diabetes

Balázs Csaba Németh, Tamás Várkonyi, Ferenc Somogyvári, Csaba Lengyel, Katalin Fehértemplomi, Szabolcs Nyiraty, Péter Kempler, Yvette Mándi

World J Gastroenterol. 2014 Jul 21; 20(27): 9128–9137. Published online 2014 Jul 21. doi: 10.3748/wjg.v20.i27.9128

PMCID:: PMC4112898

Abstract Article PDF–985K

Select item 38278129.

Human Neutrophil Peptides 1-3 – Early Markers in Development of Colorectal Adenomas and Carcinomas

Henning Mothes, Christian Melle, Günther Ernst, Roland Kaufmann, Ferdinand von Eggeling, Utz Settmacher

Dis Markers. 2008; 25(2): 123–129. Published online 2008 Oct 22. doi: 10.1155/2008/693937

PMCID:: PMC3827812

Summary PDF–120K

Select item 382659010.

Human Neutrophil Peptides 1–3 as Gastric Cancer Tissue Markers Measured by MALDI-Imaging Mass Spectrometry: Implications for Infiltrated Neutrophils as a Tumor Target

Chun-Chia Cheng, Jungshan Chang, Ling-Yun Chen, Ai-Sheng Ho, Ker-Jer Huang, Shui-Cheng Lee, Fu-Der Mai, Chun-Chao Chang

Dis Markers. 2012; 32(1): 21–31. Published online 2012 Feb 1. doi: 10.3233/DMA-2012-0857

PMCID:: PMC3826590

Summary PDF–2.6M

Select item 377350511.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 351810112.

Human α-defensin (DEFA) gene expression helps to characterise benign and malignant salivary gland tumours

Jochen Winter, Annette Pantelis, Dominik Kraus, Jan Reckenbeil, Rudolf Reich, Soeren Jepsen, Hans-Peter Fischer, Jean-Pierre Allam, Natalija Novak, Matthias Wenghoefer

BMC Cancer. 2012; 12: 465. Published online 2012 Oct 11. doi: 10.1186/1471-2407-12-465

PMCID:: PMC3518101

Abstract Article PDF–1.1M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 317517614.

Alpha-defensins 1-3 release by dendritic cells is reduced by estrogen

Maria M Escribese, Marta Rodríguez-García , Rhoda Sperling, Stephanie M Engel, Teresa Gallart, Thomas M Moran

Reprod Biol Endocrinol. 2011; 9: 118. Published online 2011 Aug 23. doi: 10.1186/1477-7827-9-118

PMCID:: PMC3175176

Abstract Article PDF–382K

Select item 316916715.

Risk of Meningioma and Common Variation in Genes related to Innate Immunity

Preetha Rajaraman, Alina V. Brenner, Gila Neta, Ruth Pfeiffer, Sophia S. Wang, Meredith Yeager, Gilles Thomas, Howard A. Fine, Martha S. Linet, Nathaniel Rothman, Stephen J. Chanock, Peter D. Inskip

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2011 Sep 7.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 May; 19(5): 1356–1361. Published online 2010 Apr 20. doi: 10.1158/1055-9965.EPI-09-1151

PMCID:: PMC3169167

Abstract Article PDF–61K

Select item 296777016.

Polymorphisms in innate immunity genes and risk of childhood leukemia

Sohee Han, Qing Lan, Ae Kyung Park, Kyoung-Mu Lee, Sue K. Park, Hyo Seop Ahn, Hee Young Shin, Hyoung Jin Kang, Hong Hoe Koo, Jong Jin Seo, Ji Eun Choi, Yoon-Ok Ahn, Stephen J. Chanock, Ho Kim, Nathaniel Rothman, Daehee Kang

Hum Immunol. Author manuscript; available in PMC 2010 Nov 2.

Published in final edited form as: Hum Immunol. 2010 Jul; 71(7): 727–730. Published online 2010 May 16. doi: 10.1016/j.humimm.2010.04.004

PMCID:: PMC2967770

Abstract Article PDF–306K

Select item 285210517.

Midpregnancy Vaginal Fluid Defensins, Bacterial Vaginosis, and Risk of Preterm Delivery

Jia Xu, Claudia B. Holzman, Cindy G. Arvidson, Hwan Chung, Alice R. Goepfert

Obstet Gynecol. Author manuscript; available in PMC 2010 Apr 9.

Published in final edited form as: Obstet Gynecol. 2008 Sep; 112(3): 524–531. doi: 10.1097/AOG.0b013e318184209b

Correction in:: volume 114 on page 380

PMCID:: PMC2852105

Abstract Article PDF–370K

Select item 282848418.

Increased α-Defensins 1-3 Production by Dendritic Cells in HIV-Infected Individuals Is Associated with Slower Disease Progression

Marta Rodríguez-García, Núria Climent, Harold Oliva, Víctor Casanova, Rafael Franco, Agathe Leon, José M. Gatell, Felipe García, Teresa Gallart

PLoS One. 2010; 5(2): e9436. Published online 2010 Feb 25. doi: 10.1371/journal.pone.0009436

PMCID:: PMC2828484

Abstract Article PDF–737K

Select item 277172319.

Common Variation in Genes Related to Innate Immunity and Risk of Adult Glioma

Preetha Rajaraman, Alina V. Brenner, Mary Ann Butler, Sophia S. Wang, Ruth M. Pfeiffer, Avima M. Ruder, Martha S. Linet, Meredith Yeager, Zhaoming Wang, Nick Orr, Howard A. Fine, Deukwoo Kwon, Gilles Thomas, Nathaniel Rothman, Peter D. Inskip, Stephen J. Chanock

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2010 May 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2009 May; 18(5): 1651–1658. doi: 10.1158/1055-9965.EPI-08-1041

PMCID:: PMC2771723

Abstract Article PDF–392K

Select item 271482020.

Gene Expression Profiles of Acute Exacerbations of Idiopathic Pulmonary Fibrosis

Kazuhisa Konishi, Kevin F. Gibson, Kathleen O. Lindell, Thomas J. Richards, Yingze Zhang, Rajiv Dhir, Michelle Bisceglia, Sebastien Gilbert, Samuel A. Yousem, Jin Woo Song, Dong Soon Kim, Naftali Kaminski

Am J Respir Crit Care Med. 2009 Jul 15; 180(2): 167–175. Published online 2009 Apr 10. doi: 10.1164/rccm.200810-1596OC