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Select item 114252831.

Furin Egress from the TGN is Regulated by Membrane‐Associated RING‐CH Finger (MARCHF) Proteins and Ubiquitin‐Specific Protease 32 (USP32) via Nondegradable K33‐Polyubiquitination

Wenqiang Su, Iqbal Ahmad, You Wu, Lijie Tang, Ilyas Khan, Bowei Ye, Jie Liang, Sunan Li, Yong‐Hui Zheng

Adv Sci (Weinh) 2024 Sep; 11(35): 2403732. Published online 2024 Jul 19. doi: 10.1002/advs.202403732

PMCID:: PMC11425283

Abstract Article PDF–6.1M

Select item 109902772.

ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton

Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012

PMCID:: PMC10990277

Abstract Article PDF–3.9M

Select item 106444233.

High USP32 expression contributes to cancer progression and is correlated with immune infiltrates in hepatocellular carcinoma

Mengxi Xiu, Wenfang Bao, Jialin Wang, Jingde Chen, Yandong Li, Yanan Hai

BMC Cancer. 2023; 23: 1105. Published online 2023 Nov 13. doi: 10.1186/s12885-023-11617-4

PMCID:: PMC10644423

Abstract Article PDF–6.7M

Select item 102374224.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101637455.

Interaction of TAGLN and USP1 promotes ZEB1 ubiquitination degradation in UV-induced skin photoaging

Yinan Li, Xiu Huang, Jing Jin, Haohao Zhang, Kai Yang, Jingxia Han, Ying Lv, Yu Sun, Cheng Yao, Tingting Lin, Caibin Zhu, Huijuan Liu

Cell Biosci. 2023; 13: 80. Published online 2023 May 6. doi: 10.1186/s13578-023-01029-z

PMCID:: PMC10163745

Abstract Article PDF–11M

Select item 101602396.

Roles of the hsa_circ_0013880/USP32/Rap1b axis in the proliferation and apoptosis of acute myeloid leukemia cells: hsa_circ_0013880/USP32/Rap1b in acute myeloid leukemia

Heyang Zhang, Yuan Tao, Xin Ding, Yue Wang, Xiaoxue Wang

Acta Biochim Biophys Sin (Shanghai) 2023 Mar; 55(3): 382–393. Published online 2023 Mar 23. doi: 10.3724/abbs.2023037

PMCID:: PMC10160239

Abstract Article PDF–3.3M

Select item 99224687.

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia

Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen

J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0

PMCID:: PMC9922468

Abstract Article PDF–4.9M

Select item 94404318.

Ubiquitin-specific protease TRE17/USP6 promotes tumor cell invasion through the regulation of glycoprotein CD147 intracellular trafficking

Yukino Ogura, Norihiko Ohbayashi, Yasunori Kanaho, Atsushi Kawaguchi, Yuji Funakoshi

J Biol Chem. 2022 Sep; 298(9): 102335. Published online 2022 Aug 2. doi: 10.1016/j.jbc.2022.102335

PMCID:: PMC9440431

Abstract Article PDF–3.2M

Select item 93485769.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 917141110.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 903755411.

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy

Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell

Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116

PMCID:: PMC9037554

Abstract Article PDF–4.1M

Select item 901883712.

Identification of ubiquitin-specific protease 32 as an oncogene in glioblastoma and the underlying mechanisms

Sifang Chen, Xi Chen, Zhangyu Li, Jianyao Mao, Weichao Jiang, Zhi Zhu, Yukui Li, Zhengye Jiang, Wenpeng Zhao, Guowei Tan, Zhanxiang Wang

Sci Rep. 2022; 12: 6445. Published online 2022 Apr 19. doi: 10.1038/s41598-022-09497-y

PMCID:: PMC9018837

Abstract Article PDF–7.9M

Select item 874895813.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 858143714.

USP32 confers cancer cell resistance to YM155 via promoting ER-associated degradation of solute carrier protein SLC35F2

Arun Pandian Chandrasekaran, Kamini Kaushal, Chang-Hwan Park, Kye-Seong Kim, Suresh Ramakrishna

Theranostics. 2021; 11(20): 9752–9771. Published online 2021 Sep 27. doi: 10.7150/thno.63806

PMCID:: PMC8581437

Abstract Article PDF–4.5M

Select item 849099715.

BioID reveals an ATG9A interaction with ATG13‐ATG101 in the degradation of p62/SQSTM1‐ubiquitin clusters

Ashari R Kannangara, Daniel M Poole, Colten M McEwan, Joshua C Youngs, Vajira K Weerasekara, Alex M Thornock, Misael T Lazaro, Eranga R Balasooriya, Laura M Oh, Erik J Soderblom, Jonathan J Lee, Daniel L Simmons, Joshua L Andersen

EMBO Rep. 2021 Oct 5; 22(10): e51136. Published online 2021 Aug 9. doi: 10.15252/embr.202051136

PMCID:: PMC8490997

Abstract Article PDF–4.5M

Select item 829296916.

Myositis Ossificans-like Soft Tissue Aneurysmal Bone Cyst: A Clinical, Radiological and Pathological Study of Seven Cases with COL1A1-USP6 fusion and a novel ANGPTL2-USP6 fusion

Lingxin Zhang, Sinchun Hwang, Ryma Benayed, Guo Zhu, Kerry A. Mullaney, Kelly M. Rios, Purvil Y Sukhadia, Narasimhan Agaram, Yanming Zhang, Julia A. Bridge, John H. Healey, Edward A. Athanasian, Meera Hameed

Mod Pathol. Author manuscript; available in PMC 2021 Jul 21.

Published in final edited form as: Mod Pathol. 2020 Aug; 33(8): 1492–1504. Published online 2020 Mar 10. doi: 10.1038/s41379-020-0513-4

PMCID:: PMC8292969

Abstract Article PDF–1.0M

Select item 828276417.

N6-methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation

Yuanming Cheng, Wei Xie, Brian F Pickering, Karen L Chu, Angela M Savino, Xuejing Yang, Hanzhi Luo, Diu TT Nguyen, Shanlan Mo, Ersilia Barin, Anthony Velleca, Thomas Rohwetter, Dinshaw J Patel, Samie R Jaffrey, Michael G Kharas

Cancer Cell. Author manuscript; available in PMC 2022 Jul 12.

Published in final edited form as: Cancer Cell. 2021 Jul 12; 39(7): 958–972.e8. Published online 2021 May 27. doi: 10.1016/j.ccell.2021.04.017

PMCID:: PMC8282764

Abstract Article PDF–3.4M

Select item 818479618.

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells

Nadia Habel, Najla El-Hachem, Frédéric Soysouvanh, Hanene Hadhiri-Bzioueche, Serena Giuliano, Sophie Nguyen, Pavel Horák, Anne-Sophie Gay, Delphine Debayle, Nicolas Nottet, Guillaume Béranger, Brigitte Bressac-de Paillerets, Corine Bertolotto, Robert Ballotti

Cell Death Differ. 2021 Jun; 28(6): 1837–1848. Published online 2021 Jan 18. doi: 10.1038/s41418-020-00710-x

PMCID:: PMC8184796

Abstract Article PDF–2.4M

Select item 816503019.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 813753420.

Ubiquitin-specific protease 6 functions as a tumor suppressor in Ewing Sarcoma through immune activation

Ian C. Henrich, Kanika Jain, Robert Young, Laura Quick, Jarrett M. Lindsay, Daniel H. Park, Andre M. Oliveira, Gerd A. Blobel, Margaret M. Chou

Cancer Res. Author manuscript; available in PMC 2021 Oct 15.

Published in final edited form as: Cancer Res. 2021 Apr 15; 81(8): 2171–2183. Published online 2021 Feb 8. doi: 10.1158/0008-5472.CAN-20-1458

PMCID:: PMC8137534

Abstract Article PDF–931K

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