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Items: 1 to 20 of 220

1.
Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment
Jie Li, Christopher R. Chin, Hsia-Yuan Ying, Cem Meydan, Matthew R. Teater, Min Xia, Pedro Farinha, Katsuyoshi Takata, Chi-Shuen Chu, Yiyue Jiang, Jenna Eagles, Verena Passerini, Zhanyun Tang, Martin A. Rivas, Oliver Weigert, Trevor J. Pugh, Amy Chadburn, Christian Steidl, David W. Scott, Robert G. Roeder, Christopher E. Mason, Roberta Zappasodi, Wendy Béguelin, Ari M. Melnick
Nat Commun. 2024; 15: 2879. Published online 2024 Apr 3. doi: 10.1038/s41467-024-47012-1
PMCID:
PMC10991284
AbstractArticlePDF–7.3M
2.
CBP/p300 and HDAC activities regulate H3K27 acetylation dynamics and zygotic genome activation in mouse preimplantation embryos
Meng Wang, Zhiyuan Chen, Yi Zhang
EMBO J. 2022 Nov; 41(22): e112012. Published online 2022 Oct 10. doi: 10.15252/embj.2022112012
PMCID:
PMC9670200
AbstractArticlePDF–4.1M
3.
CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder
Aurélie de Thonel, Johanna K. Ahlskog, Kevin Daupin, Véronique Dubreuil, Jérémy Berthelet, Carole Chaput, Geoffrey Pires, Camille Leonetti, Ryma Abane, Lluís Cordón Barris, Isabelle Leray, Anna L. Aalto, Sarah Naceri, Marine Cordonnier, Carène Benasolo, Matthieu Sanial, Agathe Duchateau, Anniina Vihervaara, Mikael C. Puustinen, Federico Miozzo, Patricia Fergelot, Élise Lebigot, Alain Verloes, Pierre Gressens, Didier Lacombe, Jessica Gobbo, Carmen Garrido, Sandy D. Westerheide, Laurent David, Michel Petitjean, Olivier Taboureau, Fernando Rodrigues-Lima, Sandrine Passemard, Délara Sabéran-Djoneidi, Laurent Nguyen, Madeline Lancaster, Lea Sistonen, Valérie Mezger
Nat Commun. 2022; 13: 7002. Published online 2022 Nov 16. doi: 10.1038/s41467-022-34476-2
Correction in:
Nat Commun. 2023; 14: 6067.
PMCID:
PMC9668993
AbstractArticlePDF–9.1M
4.
CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain
Michal Lipinski, Sergio Niñerola, Miguel Fuentes-Ramos, Luis M. Valor, Beatriz del Blanco, Jose P. López-Atalaya, Angel Barco
J Neurosci. 2022 Oct 19; 42(42): 7984–8001. doi: 10.1523/JNEUROSCI.0970-22.2022
PMCID:
PMC9617619
AbstractArticlePDF–6.0M
5.
Inhibition of CBP/β‐catenin signaling ameliorated fibrosis in cholestatic liver disease
Masamichi Kimura, Koji Nishikawa, Yosuke Osawa, Jun Imamura, Kenzaburo Yamaji, Kenichi Harada, Hiroshi Yatsuhashi, Kazumoto Murata, Kouichi Miura, Atsushi Tanaka, Tatsuya Kanto, Michinori Kohara, Terumi Kamisawa, Kiminori Kimura
Hepatol Commun. 2022 Oct; 6(10): 2732–2747. Published online 2022 Jul 20. doi: 10.1002/hep4.2043
PMCID:
PMC9512479
AbstractArticlePDF–19M
6.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
7.
Characterization of the high-affinity fuzzy complex between the disordered domain of the E7 oncoprotein from high-risk HPV and the TAZ2 domain of CBP
Michael W. Risør, Ariane L. Jansma, Natasha Medici, Brittany Thomas, H. Jane Dyson, Peter E. Wright
Biochemistry. Author manuscript; available in PMC 2022 Dec 28.
Published in final edited form as: Biochemistry. 2021 Dec 28; 60(51): 3887–3898. Published online 2021 Dec 14. doi: 10.1021/acs.biochem.1c00669
PMCID:
PMC8865373
AbstractArticlePDF–1.9M
8.
p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes
Vitor F. Martins, Samuel A. LaBarge, Alexandra Stanley, Kristoffer Svensson, Chao-Wei Hung, Omer Keinan, Theodore P. Ciaraldi, Dion Banoian, Ji E. Park, Christina Ha, Byron Hetrick, Gretchen A. Meyer, Andrew Philp, Larry L. David, Robert R. Henry, Joseph E. Aslan, Alan R. Saltiel, Carrie. E. McCurdy, Simon Schenk
JCI Insight. 2022 Jan 11; 7(1): e141344. Published online 2022 Jan 11. doi: 10.1172/jci.insight.141344
PMCID:
PMC8765050
AbstractArticlePDF–6.0M
9.
A propolis-derived small molecule ameliorates metabolic syndrome in obese mice by targeting the CREB/CRTC2 transcriptional complex
Yaqiong Chen, Jiang Wang, Yibing Wang, Pengfei Wang, Zan Zhou, Rong Wu, Qian Xu, Hanyun You, Yaxin Liu, Lei Wang, Lingqin Zhou, Yuting Wu, Lihong Hu, Hong Liu, Yi Liu
Nat Commun. 2022; 13: 246. Published online 2022 Jan 11. doi: 10.1038/s41467-021-27533-9
PMCID:
PMC8752738
AbstractArticlePDF–1.7M
10.
NRF1 Association with AUTS2-Polycomb Mediates Specific Gene Activation in the Brain
Sanxiong Liu, Kimberly A. Aldinger, Chi Vicky Cheng, Takae Kiyama, Mitali Dave, Hanna K. McNamara, Wukui Zhao, James M. Stafford, Nicolas Descostes, Pedro Lee, Stefano G. Caraffi, Ivan Ivanovski, Edoardo Errichiello, Christiane Zweier, Orsetta Zuffardi, Michael Schneider, Antigone S. Papavasiliou, M. Scott Perry, Jennifer Humberson, Megan T. Cho, Astrid Weber, Andrew Swale, Tudor C. Badea, Chai-An Mao, Livia Garavelli, William B. Dobyns, Danny Reinberg
Mol Cell. Author manuscript; available in PMC 2022 Nov 18.
Published in final edited form as: Mol Cell. 2021 Nov 18; 81(22): 4663–4676.e8. Published online 2021 Oct 11. doi: 10.1016/j.molcel.2021.09.020
Correction in:
Mol Cell. 2021 Nov 18; 81(22): 4757.
PMCID:
PMC8604784
AbstractArticlePDF–2.8M
11.
Antisense-induced knockdown of CREB-binding protein (CBP) downregulates Per1 gene expression in the shell region of nucleus accumbens resulting in reduced alcohol consumption in mice
Rishi Sharma, Vaibhav Mishra, Meet Parikh, Anshul Soni, Pradeep Sahota, Mahesh Thakkar
Alcohol Clin Exp Res. Author manuscript; available in PMC 2022 Oct 1.
Published in final edited form as: Alcohol Clin Exp Res. 2021 Oct; 45(10): 1940–1949. Published online 2021 Aug 23. doi: 10.1111/acer.14687
PMCID:
PMC8602740
AbstractArticlePDF–1.2M
12.
Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation
Teresa Romeo Luperchio, Leandros Boukas, Li Zhang, Genay Pilarowski, Jenny Jiang, Allison Kalinousky, Kasper D Hansen, Hans T Bjornsson
eLife. 2021; 10: e65884. Published online 2021 Aug 31. doi: 10.7554/eLife.65884
PMCID:
PMC8443249
AbstractArticlePDF–7.0M
13.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
14.
TRIM33 protects osteoblasts from oxidative stress‐induced apoptosis in osteoporosis by inhibiting FOXO3a ubiquitylation and degradation
De‐bo Zou, Zongyou Mou, Wenliang Wu, Haichun Liu
Aging Cell. 2021 Jul; 20(7): e13367. Published online 2021 Jun 8. doi: 10.1111/acel.13367
PMCID:
PMC8282270
AbstractArticlePDF–1.8M
15.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
16.
CBP Bromodomain Inhibition Rescues Mice From Lethal Sepsis Through Blocking HMGB1-Mediated Inflammatory Responses
Xiaowen Bi, Baolin Jiang, Jinyi Zhou, Xirui Fan, Xintong Yan, Juanjuan Liang, Lan Luo, Zhimin Yin
Front Immunol. 2020; 11: 625542. Published online 2021 Feb 2. doi: 10.3389/fimmu.2020.625542
PMCID:
PMC7884462
AbstractArticlePDF–7.3M
17.
CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300 mutated lymphomas
Kylee J. Veazey, Donghang Cheng, Kevin Lin, Oscar D. Villarreal, Guozhen Gao, Mabel Perez-Oquendo, Hieu T. Van, Sabrina A. Stratton, Michael Green, Han Xu, Yue Lu, Mark T. Bedford, Margarida Almeida Santos
Leukemia. Author manuscript; available in PMC 2020 Dec 24.
Published in final edited form as: Leukemia. 2020 Dec; 34(12): 3269–3285. Published online 2020 Jun 24. doi: 10.1038/s41375-020-0908-8
PMCID:
PMC7688486
AbstractArticlePDF–3.1M
18.
The CBP KIX domain regulates long-term memory and circadian activity
Snehajyoti Chatterjee, Christopher C. Angelakos, Ethan Bahl, Joshua D. Hawk, Marie E. Gaine, Shane G. Poplawski, Anne Schneider-Anthony, Manish Yadav, Giulia S. Porcari, Jean-Christophe Cassel, K. Peter Giese, Jacob J. Michaelson, Lisa C. Lyons, Anne-Laurence Boutillier, Ted Abel
BMC Biol. 2020; 18: 155. Published online 2020 Oct 29. doi: 10.1186/s12915-020-00886-1
PMCID:
PMC7597000
AbstractArticlePDF–3.5M
19.
Differential contribution of p300 and CBP to regulatory element acetylation in mESCs
Sara Martire, Jennifer Nguyen, Aishwarya Sundaresan, Laura A. Banaszynski
BMC Mol Cell Biol. 2020; 21: 55. Published online 2020 Jul 20. doi: 10.1186/s12860-020-00296-9
PMCID:
PMC7370441
AbstractArticlePDF–1.7M
20.
Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma
Stefanie N. Meyer, Claudio Scuoppo, Sofija Vlasevska, Elodie Bal, Antony B. Holmes, Mara Holloman, Laura Garcia-Ibanez, Sarah Nataraj, Romain Duval, Thomas Vantrimpont, Katia Basso, Nigel Brooks, Riccardo Dalla-Favera, Laura Pasqualucci
Immunity. Author manuscript; available in PMC 2020 Sep 17.
Published in final edited form as: Immunity. 2019 Sep 17; 51(3): 535–547.e9. Published online 2019 Sep 10. doi: 10.1016/j.immuni.2019.08.006
PMCID:
PMC7362711
AbstractArticlePDF–2.5M

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