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Select item 111083861.

β-Arrestin scaffolds and signaling elements essential for the obestatin/GPR39 system that determine the myogenic program in human myoblast cells

Icía Santos-Zas, Uxía Gurriarán-Rodríguez, Tania Cid-Díaz, Gabriela Figueroa, Jessica González-Sánchez, Mónica Bouzo-Lorenzo, Carlos S. Mosteiro, José Señarís, Felipe F. Casanueva, Xesús Casabiell, Rosalía Gallego, Yolanda Pazos, Vincent Mouly, Jesús P. Camiña

Cell Mol Life Sci. 2016 Feb; 73(3): 617–635. Published online 2015 Jul 27. doi: 10.1007/s00018-015-1994-z

PMCID:: PMC11108386

Abstract Article PDF–7.1M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101328053.

Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs

Filip Mihalič, Leandro Simonetti, Girolamo Giudice, Marie Rubin Sander, Richard Lindqvist, Marie Berit Akpiroro Peters, Caroline Benz, Eszter Kassa, Dilip Badgujar, Raviteja Inturi, Muhammad Ali, Izabella Krystkowiak, Ahmed Sayadi, Eva Andersson, Hanna Aronsson, Ola Söderberg, Doreen Dobritzsch, Evangelia Petsalaki, Anna K. Överby, Per Jemth, Norman E. Davey, Ylva Ivarsson

Nat Commun. 2023; 14: 2409. Published online 2023 Apr 26. doi: 10.1038/s41467-023-38015-5

PMCID:: PMC10132805

Abstract Article PDF–4.2M

Select item 100085204.

Dysregulated Smooth Muscle Cell BMPR2 – ARRB2 Axis Causes Pulmonary Hypertension

Lingli Wang, Jan Renier Moonen, Aiqin Cao, Sarasa Isobe, Caiyun G Li, Nancy F Tojais, Shalina Taylor, David P Marciano, Pin-I Chen, Mingxia Gu, Dan Li, Rebecca L Harper, Nesrine El-Bizri, YuMee Kim, Kryn Stankunas, Marlene Rabinovitch

Circ Res. Author manuscript; available in PMC 2024 Mar 3.

Published in final edited form as: Circ Res. 2023 Mar 3; 132(5): 545–564. Published online 2023 Feb 6. doi: 10.1161/CIRCRESAHA.121.320541

PMCID:: PMC10008520

Abstract Article PDF–4.4M

Select item 95883435.

The Comprehensive Analysis of Hub Gene ARRB2 in Prostate Cancer

Bing Zhou, Hong Song, Wuqin Xu, Yanbin Zhang, Yinhua Liu, Wei Qi

Dis Markers. 2022; 2022: 8518378. Published online 2022 Oct 15. doi: 10.1155/2022/8518378

PMCID:: PMC9588343

Abstract Article PDF–3.7M

Select item 94992386.

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein

Marius Walter, Irene P. Chen, Albert Vallejo-Gracia, Ik-Jung Kim, Olga Bielska, Victor L. Lam, Jennifer M. Hayashi, Andrew Cruz, Samah Shah, Frank W. Soveg, John D. Gross, Nevan J. Krogan, Keith R. Jerome, Birgit Schilling, Melanie Ott, Eric Verdin

PLoS Pathog. 2022 Sep; 18(9): e1010811. Published online 2022 Sep 12. doi: 10.1371/journal.ppat.1010811

PMCID:: PMC9499238

Abstract Article PDF–3.7M

Select item 88970227.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 87690728.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 87633179.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

Abstract Article

Select item 866079110.

Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR

Yutaro Shiraishi, Yutaka Kofuku, Takumi Ueda, Shubhi Pandey, Hemlata Dwivedi-Agnihotri, Arun K. Shukla, Ichio Shimada

Nat Commun. 2021; 12: 7158. Published online 2021 Dec 9. doi: 10.1038/s41467-021-27482-3

PMCID:: PMC8660791

Abstract Article PDF–1.7M

Select item 856393411.

β-arrestin 2 stimulates degradation of HIF-1α and modulates tumor progression of glioblastoma

Woom-Yee Bae, Jae-Sun Choi, Seungyoon Nam, Joo-Won Jeong

Cell Death Differ. 2021 Nov; 28(11): 3092–3104. Published online 2021 May 18. doi: 10.1038/s41418-021-00802-2

PMCID:: PMC8563934

Abstract Article PDF–2.2M

Select item 851385312.

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari

PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412

PMCID:: PMC8513853

Abstract Article PDF–4.1M

Select item 844941013.

Scaffolding mechanism of arrestin-2 in the cRaf/MEK1/ERK signaling cascade

Changxiu Qu, Ji Young Park, Min Woo Yun, Qing-tao He, Fan Yang, Kiae Kim, Donghee Ham, Rui-rui Li, T. M. Iverson, Vsevolod V. Gurevich, Jin-Peng Sun, Ka Young Chung

Proc Natl Acad Sci U S A. 2021 Sep 14; 118(37): e2026491118. Published online 2021 Sep 10. doi: 10.1073/pnas.2026491118

PMCID:: PMC8449410

Abstract Article PDF–1.6M

Select item 841548314.

Biased Coupling to β-Arrestin of Two Common Variants of the CB₂ Cannabinoid Receptor

Gábor Turu, Eszter Soltész-Katona, András Dávid Tóth, Cintia Juhász, Miklós Cserző, Ádám Misák, András Balla, Marc G. Caron, László Hunyady

Front Endocrinol (Lausanne) 2021; 12: 714561. Published online 2021 Aug 16. doi: 10.3389/fendo.2021.714561

PMCID:: PMC8415483

Abstract Article PDF–6.7M

Select item 824377415.

β-arrestin2 (ARRB2) Polymorphism Associated with the Adverse Consequences of Chronic Heroin Use

Klevis K. Karavidha, Margit Burmeister, Mark K. Greenwald

Am J Addict. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Am J Addict. 2021 Jul; 30(4): 351–357. Published online 2021 Mar 30. doi: 10.1111/ajad.13150

PMCID:: PMC8243774

Abstract Article PDF–548K

Select item 822311916.

ACE2 interaction with cytoplasmic PDZ protein enhances SARS-CoV-2 invasion

Qiangmin Zhang, Julia Gefter, W. Bruce Sneddon, Tatyana Mamonova, Peter A. Friedman

iScience. 2021 Jul 23; 24(7): 102770. Published online 2021 Jun 24. doi: 10.1016/j.isci.2021.102770

PMCID:: PMC8223119

Abstract Article PDF–3.0M

Select item 821568617.

Structural insights into the human D1 and D2 dopamine receptor signaling complexes

Youwen Zhuang, Peiyu Xu, Chunyou Mao, Lei Wang, Brian Krumm, X. Edward Zhou, Sijie Huang, Heng Liu, Xi Cheng, Xi-Ping Huang, Dan-Dan Shen, Tinghai Xu, Yong-Feng Liu, Yue Wang, Jia Guo, Yi Jiang, Hualiang Jiang, Karsten Melcher, Bryan L. Roth, Yan Zhang, Cheng Zhang, H. Eric Xu

Cell. Author manuscript; available in PMC 2021 Jun 21.

Published in final edited form as: Cell. 2021 Feb 18; 184(4): 931–942.e18. Published online 2021 Feb 10. doi: 10.1016/j.cell.2021.01.027

PMCID:: PMC8215686

Abstract Article PDF–3.1M

Select item 816503018.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 816305419.

Host versus cell-dependent effects of β-arrestin 1 expression in prostate tumorigenesis

Timothy O Adekoya, Nikia Smith, Ariel J Thomas, Tonya S Lane, Nija Burnette, Elizabeth J Rivers, Yahui Li, Xiaoxin L Chen, Ricardo M Richardson

Carcinogenesis. 2021 May; 42(5): 772–783. Published online 2021 Mar 12. doi: 10.1093/carcin/bgab021

PMCID:: PMC8163054

Abstract Article PDF–15M

Select item 794845220.

A conserved acetylation switch enables pharmacological control of tubby-like protein stability

Evan M. Kerek, Kevin H. Yoon, Shu Y. Luo, Jerry Chen, Robert Valencia, Olivier Julien, Andrew J. Waskiewicz, Basil P. Hubbard

J Biol Chem. 2021 Jan-Jun; 296: 100073. Published online 2020 Nov 23. doi: 10.1074/jbc.RA120.015839

PMCID:: PMC7948452

Abstract Article PDF–3.6M

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