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Select item 88970221.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 88633082.

A year of COVID-19 GWAS results from the GRASP portal reveals potential genetic risk factors

Florian Thibord, Melissa V. Chan, Ming-Huei Chen, Andrew D. Johnson

HGG Adv. 2022 Apr 14; 3(2): 100095. Published online 2022 Feb 22. doi: 10.1016/j.xhgg.2022.100095

PMCID:: PMC8863308

Abstract Article PDF–1.0M

Select item 84905753.

ASIC2 Synergizes with TRPV1 in the Mechano-Electrical Transduction of Arterial Baroreceptors

Xiaodong Yan, Sitao Zhang, Haiyan Zhao, Ping Liu, Haixia Huang, Weizhen Niu, Wei Wang, Chen Zhang

Neurosci Bull. 2021 Oct; 37(10): 1381–1396. Published online 2021 Jul 2. doi: 10.1007/s12264-021-00737-1

PMCID:: PMC8490575

Abstract Article PDF–1.9M

Select item 81996444.

Expression Profiles of ASIC1/2 and TRPV1/4 in Common Skin Tumors

Kirsten Ackermann, Susanne Wallner, Christoph Brochhausen, Stephan Schreml

Int J Mol Sci. 2021 Jun; 22(11): 6024. Published online 2021 Jun 2. doi: 10.3390/ijms22116024

PMCID:: PMC8199644

Abstract Article PDF–68M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76060086.

BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A

Chun‐guo Mao, Sha‐sha Jiang, Cheng Shen, Tan Long, Hua Jin, Qun‐You Tan, Bo Deng

Thorac Cancer. 2020 Nov; 11(11): 3326–3336. Published online 2020 Oct 1. doi: 10.1111/1759-7714.13676

PMCID:: PMC7606008

Abstract Article PDF–2.5M

Select item 67203667.

High Expression of Acid-Sensing Ion Channel 2 (ASIC2) in Bone Cells in Osteoporotic Vertebral Fractures

Ching-Yu Lee, Tsung-Jen Huang, Meng-Huang Wu, Yen-Yao Li, Kuan-Der Lee

Biomed Res Int. 2019; 2019: 4714279. Published online 2019 Aug 19. doi: 10.1155/2019/4714279

PMCID:: PMC6720366

Abstract Article PDF–1.3M

Select item 66182688.

Acid sensing ion channel 2: A new potential player in the pathophysiology of multiple sclerosis

Teresa Fazia, Roberta Pastorino, Serena Notartomaso, Carla Busceti, Tiziana Imbriglio, Milena Cannella, Davide Gentilini, Gabriele Morani, Anna Ticca, Pierpaolo Bitti, Carlo Berzuini, Tamas Dalmay, Giuseppe Battaglia, Luisa Bernardinelli

Eur J Neurosci. 2019 May; 49(10): 1233–1243. Published online 2019 Feb 19. doi: 10.1111/ejn.14302

PMCID:: PMC6618268

Abstract Article PDF–797K

Select item 56060379.

The acid-sensing ion channel, ASIC2, promotes invasion and metastasis of colorectal cancer under acidosis by activating the calcineurin/NFAT1 axis

Zhi-hang Zhou, Jin-wen Song, Wen Li, Xue Liu, Liu Cao, Lu-ming Wan, Ying-xia Tan, Shou-ping Ji, Yu-mei Liang, Feng Gong

J Exp Clin Cancer Res. 2017; 36: 130. Published online 2017 Sep 19. doi: 10.1186/s13046-017-0599-9

PMCID:: PMC5606037

Abstract Article PDF–5.8M

Select item 553161110.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 551760411.

Glucose Deficiency Elevates Acid-Sensing Ion Channel 2a Expression and Increases Seizure Susceptibility in Temporal Lobe Epilepsy

Haitao Zhang, Guodong Gao, Yu Zhang, Yang Sun, Huanfa Li, Shan Dong, Wei Ma, Bei Liu, Weiwen Wang, Hao Wu, Hua Zhang

Sci Rep. 2017; 7: 5870. Published online 2017 Jul 19. doi: 10.1038/s41598-017-05038-0

PMCID:: PMC5517604

Abstract Article PDF–5.1M

Select item 499529312.

The function and regulation of acid‐sensing ion channels (ASICs) and the epithelial Na⁺ channel (ENaC): IUPHAR Review 19

Emilie Boscardin, Omar Alijevic, Edith Hummler, Simona Frateschi, Stephan Kellenberger

Br J Pharmacol. 2016 Sep; 173(18): 2671–2701. Published online 2016 Aug 10. doi: 10.1111/bph.13533

PMCID:: PMC4995293

Abstract Article PDF–1.6M

Select item 496792713.

Acid-Sensing Ion Channel 2a (ASIC2a) Promotes Surface Trafficking of ASIC2b via Heteromeric Assembly

Hae-Jin Kweon, Dong-Il Kim, Yeonju Bae, Jae-Yong Park, Byung-Chang Suh

Sci Rep. 2016; 6: 30684. Published online 2016 Aug 1. doi: 10.1038/srep30684

PMCID:: PMC4967927

Abstract Article PDF–2.7M

Select item 463755314.

Acid-sensing ion channel 2 (asic 2) and trkb interrelationships within the intervertebral disc

Antonio Cuesta, Eliseo Viña, Roberto Cabo, Gorka Vázquez, Ramón Cobo, Olivia García-Suárez, José García-Cosamalón, José A Vega

Int J Clin Exp Pathol. 2015; 8(9): 10305–10314. Published online 2015 Sep 1.

PMCID:: PMC4637553

Abstract Article PDF–1.0M

Select item 405060015.

Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometry

Tudor Bartoi, Katrin Augustinowski, Georg Polleichtner, Stefan Gründer, Maximilian H. Ulbrich

Proc Natl Acad Sci U S A. 2014 Jun 3; 111(22): 8281–8286. Published online 2014 May 20. doi: 10.1073/pnas.1324060111

PMCID:: PMC4050600

Abstract Article PDF–1.1M

Select item 385466916.

Genome Wide Association Study (GWAS) of Chagas Cardiomyopathy in Trypanosoma cruzi Seropositive Subjects

Xutao Deng, Ester C. Sabino, Edecio Cunha-Neto, Antonio L. Ribeiro, Barbara Ianni, Charles Mady, Michael P. Busch, Mark Seielstad, the REDSII Chagas study group from the NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), International Component

PLoS One. 2013; 8(11): e79629. Published online 2013 Nov 20. doi: 10.1371/journal.pone.0079629

PMCID:: PMC3854669

Abstract Article PDF–408K

Select item 379979717.

A Kinase-anchoring Protein 150 and Calcineurin Are Involved in Regulation of Acid-sensing Ion Channels ASIC1a and ASIC2a

Sunghee Chai, Minghua Li, JingQuan Lan, Zhi-Gang Xiong, Julie A. Saugstad, Roger P. Simon

J Biol Chem. Author manuscript; available in PMC 2013 Oct 19.

Published in final edited form as: J Biol Chem. 2007 Aug 3; 282(31): 22668–22677. Published online 2007 Jun 4. doi: 10.1074/jbc.M703624200

PMCID:: PMC3799797

Abstract Article PDF–1.5M

Select item 352258718.

Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population

Anthony G. Comuzzie, Shelley A. Cole, Sandra L. Laston, V. Saroja Voruganti, Karin Haack, Richard A. Gibbs, Nancy F. Butte

PLoS One. 2012; 7(12): e51954. Published online 2012 Dec 14. doi: 10.1371/journal.pone.0051954

PMCID:: PMC3522587

Abstract Article PDF–130K

Select item 332102319.

Novel Associations for Hypothyroidism Include Known Autoimmune Risk Loci

Nicholas Eriksson, Joyce Y. Tung, Amy K. Kiefer, David A. Hinds, Uta Francke, Joanna L. Mountain, Chuong B. Do

PLoS One. 2012; 7(4): e34442. Published online 2012 Apr 6. doi: 10.1371/journal.pone.0034442

PMCID:: PMC3321023

Abstract Article PDF–750K

Select item 323451620.

A genome-wide study of panic disorder suggests the amiloride-sensitive cation channel 1 as a candidate gene

Noomi Gregersen, Hans A Dahl, Henriette N Buttenschøn, Mette Nyegaard, Anne Hedemand, Thomas D Als, August G Wang, Sofus Joensen, David PD Woldbye, Pernille Koefoed, Ann S Kristensen, Torben A Kruse, Anders D Børglum, Ole Mors

Eur J Hum Genet. 2012 Jan; 20(1): 84–90. Published online 2011 Aug 3. doi: 10.1038/ejhg.2011.148

PMCID:: PMC3234516

Abstract Article PDF–390K

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