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Select item 110314051.

Inhibition of S6K lowers age-related inflammation and increases lifespan through the endolysosomal system

Pingze Zhang, James H. Catterson, Sebastian Grönke, Linda Partridge

Nat Aging. 2024; 4(4): 491–509. Published online 2024 Feb 27. doi: 10.1038/s43587-024-00578-3

PMCID:: PMC11031405

Abstract Article PDF–12M

Select item 109454002.

When the microbiome shapes the host: immune evolution implications for infectious disease

Mark A. Hanson

Philos Trans R Soc Lond B Biol Sci. May 6, 2024; 379(1901): 20230061. Published online March 18, 2024. doi: 10.1098/rstb.2023.0061

PMCID:: PMC10945400

Abstract Article PDF–667K

Select item 108162823.

The Lifespan of D. melanogaster Depends on the Function of the Gagr Gene, a Domesticated gag Gene of Drosophila LTR Retrotransposons

Yevgenia Balakireva, Maria Nikitina, Pavel Makhnovskii, Inna Kukushkina, Ilya Kuzmin, Alexander Kim, Lidia Nefedova

Insects. 2024 Jan; 15(1): 68. Published online 2024 Jan 17. doi: 10.3390/insects15010068

PMCID:: PMC10816282

Abstract Article PDF–4.1M

Select item 107737984.

Recent trends in insect gut immunity

Shahidul Ahmed Khan, Maryam Ali Mohmmadie Kojour, Yeon Soo Han

Front Immunol. 2023; 14: 1272143. Published online 2023 Dec 18. doi: 10.3389/fimmu.2023.1272143

PMCID:: PMC10773798

Abstract Article PDF–7.2M

Select item 107326905.

A Drosophila melanogaster model shows that fast growing Metarhizium species are the deadliest despite eliciting a strong immune response

Jonathan B. Wang, Hsiao-Ling Lu, Huiyu Sheng, Raymond J St. Leger

Virulence. 2023; 14(1): 2275493. Published online 2023 Nov 8. doi: 10.1080/21505594.2023.2275493

PMCID:: PMC10732690

Abstract Article PDF–4.7M

Select item 106170086.

Regulating metabolism to shape immune function: Lessons from Drosophila

Michelle L. Bland

Semin Cell Dev Biol. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Semin Cell Dev Biol. 2023 Mar 30; 138: 128–141. Published online 2022 Apr 16. doi: 10.1016/j.semcdb.2022.04.002

PMCID:: PMC10617008

Abstract Article PDF–954K

Select item 106016647.

Perilipin 1 Deficiency Prompts Lipolysis in Lipid Droplets and Aggravates the Pathogenesis of Persistent Immune Activation in Drosophila

Lei Wang, Jiaxin Lin, Kaiyan Yang, Weina Wang, Yan Lv, Xiangkang Zeng, Yaya Zhao, Junjing Yu, Lei Pan

J Innate Immun. 2023 Jan-Dec; 15(1): 697–708. Published online 2023 Sep 23. doi: 10.1159/000534099

PMCID:: PMC10601664

Abstract Article PDF–2.1M

Select item 105907078.

Drosophila Gut Immune Pathway Suppresses Host Development-Promoting Effects of Acetic Acid Bacteria

Jaegeun Lee, Xinge Song, Bom Hyun, Che Ok Jeon, Seogang Hyun

Mol Cells. 2023 Oct 31; 46(10): 637–653. Published online 2023 Sep 22. doi: 10.14348/molcells.2023.0141

PMCID:: PMC10590707

Abstract Article PDF–1.1M

Select item 105609929.

Immunometabolic regulation during the presence of microorganisms and parasitoids in insects

Shirong Li, Jing Wang, Xing Tian, Shahzad Toufeeq, Wuren Huang

Front Immunol. 2023; 14: 905467. Published online 2023 Sep 25. doi: 10.3389/fimmu.2023.905467

PMCID:: PMC10560992

Abstract Article PDF–1.4M

Select item 1055668110.

Stilbenoid compounds inhibit NF-κB-mediated inflammatory responses in the Drosophila intestine

Anna L. Aalto, Atefeh Saadabadi, Fanny Lindholm, Christa Kietz, Emmy Himmelroos, Parthiban Marimuthu, Outi M. H. Salo-Ahen, Patrik Eklund, Annika Meinander

Front Immunol. 2023; 14: 1253805. Published online 2023 Sep 22. doi: 10.3389/fimmu.2023.1253805

PMCID:: PMC10556681

Abstract Article PDF–4.8M

Select item 1041180911.

Heuristic-enabled active machine learning: A case study of predicting essential developmental stage and immune response genes in Drosophila melanogaster

Olufemi Tony Aromolaran, Itunu Isewon, Eunice Adedeji, Marcus Oswald, Ezekiel Adebiyi, Rainer Koenig, Jelili Oyelade

PLoS One. 2023; 18(8): e0288023. Published online 2023 Aug 9. doi: 10.1371/journal.pone.0288023

Correction in:: PLoS One. 2024; 19(6): e0305979.

PMCID:: PMC10411809

Abstract Article PDF–2.0M

Select item 1038757612.

Role of Rab5 early endosomes in regulating Drosophila gut antibacterial response

Manish Joshi, Annelise Viallat-Lieutaud, Julien Royet

iScience. 2023 Aug 18; 26(8): 107335. Published online 2023 Jul 10. doi: 10.1016/j.isci.2023.107335

PMCID:: PMC10387576

Abstract Article PDF–6.7M

Select item 1038747213.

Drosophila innate immunity suppresses the survival of xenografted mammalian tumor cells

Ayaka Aida, Kevin Yuswan, Yoichi Kawai, Keita Hasegawa, Yu-ichiro Nakajima, Erina Kuranaga

Sci Rep. 2023; 13: 12334. Published online 2023 Jul 30. doi: 10.1038/s41598-023-38489-9

PMCID:: PMC10387472

Abstract Article PDF–4.8M

Select item 1031778414.

Interactions with ectoparasitic mites induce host metabolic and immune responses in flies at the expense of reproduction-associated factors

Joshua B. Benoit, Joy Bose, Samuel T. Bailey, Michal Polak

Parasitology. 2020 Sep; 147(11): 1196–1205. Published online 2020 Jun 5. doi: 10.1017/S0031182020000918

PMCID:: PMC10317784

Abstract Article PDF–602K

Select item 1027036015.

Steroid hormone regulation of innate immunity in Drosophila melanogaster

Scott A. Keith

PLoS Genet. 2023 Jun; 19(6): e1010782. Published online 2023 Jun 15. doi: 10.1371/journal.pgen.1010782

PMCID:: PMC10270360

Abstract Article PDF–1.0M

Select item 1022048816.

Peptidoglycan recognition in Drosophila is mediated by LysMD3/4

Mark Snee, Jason Wever, Jennifer Guyton, Ryan Beehler-Evans, Christine C. Yokoyama, Craig A. Micchelli

J Biol Chem. 2023 Jun; 299(6): 104758. Published online 2023 Apr 26. doi: 10.1016/j.jbc.2023.104758

PMCID:: PMC10220488

Abstract Article PDF–3.2M

Select item 1011278917.

Recognition of commensal bacterial peptidoglycans defines Drosophila gut homeostasis and lifespan

Taro Onuma, Toshitaka Yamauchi, Hina Kosakamoto, Hibiki Kadoguchi, Takayuki Kuraishi, Takumi Murakami, Hiroshi Mori, Masayuki Miura, Fumiaki Obata

PLoS Genet. 2023 Apr; 19(4): e1010709. Published online 2023 Apr 6. doi: 10.1371/journal.pgen.1010709

PMCID:: PMC10112789

Abstract Article PDF–3.2M

Select item 1010573618.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 1006635219.

Single Cell Analysis of the Fate of Injected Oncogenic RasV12 Cells in Adult Wild Type Drosophila

Di Chen, Xiao Lan, Xiaoming Huang, Jieqing Huang, Xiaojing Zhou, Zhichao Miao, Yuting Ma, Akira Goto, Shanming Ji, Jules A. Hoffmann

J Innate Immun. 2023 Jan-Dec; 15(1): 442–467. Published online 2023 Mar 30. doi: 10.1159/000529096

PMCID:: PMC10066352

Abstract Article PDF–6.1M

Select item 1006321820.

The Effect of Developmental Pleiotropy on the Evolution of Insect Immune Genes

Alissa M Williams, Thi Minh Ngo, Veronica E Figueroa, Ann T Tate

Genome Biol Evol. 2023 Mar; 15(3): evad044. Published online 2023 Mar 13. doi: 10.1093/gbe/evad044

PMCID:: PMC10063218

Abstract Article PDF–2.1M

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