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Items: 1 to 20 of 134

1.
Single-cell transcriptomics reveals the cellular identity of a novel progenitor population crucial for murine neural tube closure
Zihao Deng, Marina R. Carpinelli, Tariq Butt, Graham W. Magor, Peinan Zhao, Kevin R. Gillinder, Andrew C. Perkins, Stephen M. Jane
Heliyon. 2024 Sep 15; 10(17): e37259. Published online 2024 Aug 30. doi: 10.1016/j.heliyon.2024.e37259
PMCID:
PMC11408003
AbstractArticlePDF–14M
2.
Dysregulation of Grainyhead‐like 3 expression causes widespread developmental defects
Zihao Deng, Tariq Butt, Benedicta D. Arhatari, Charbel Darido, Alana Auden, Dijina Swaroop, Darren D. Partridge, Katharina Haigh, Thao Nguyen, Jody J. Haigh, Marina R. Carpinelli, Stephen M. Jane
Dev Dyn. 2023 May; 252(5): 647–667. Published online 2023 Jan 19. doi: 10.1002/dvdy.565
PMCID:
PMC10952483
AbstractArticlePDF–23M
3.
Competition between skin antimicrobial peptides and commensal bacteria in type 2 inflammation enables survival of S. aureus
Teruaki Nakatsuji, Samantha L. Brinton, Kellen J. Cavagnero, Alan M. O’Neill, Yang Chen, Tatsuya Dokoshi, Anna M. Butcher, Olive C. Osuoji, Faiza Shafiq, Josh L. Espinoza, Christopher L. Dupont, Tissa R. Hata, Richard L. Gallo
Cell Rep. Author manuscript; available in PMC 2023 Jun 28.
Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112494. Published online 2023 May 10. doi: 10.1016/j.celrep.2023.112494
PMCID:
PMC10303920
AbstractArticlePDF–2.5M
4.
ZFP750 affects the cutaneous barrier through regulating lipid metabolism
Alessio Butera, Massimiliano Agostini, Matteo Cassandri, Francesca De Nicola, Maurizio Fanciulli, Lorenzo D’Ambrosio, Laura Falasca, Roberta Nardacci, Lu Wang, Mauro Piacentini, Richard A. Knight, Wei Jia, Qiang Sun, Yufang Shi, Ying Wang, Eleonora Candi, Gerry Melino
Sci Adv. 2023 Apr; 9(17): eadg5423. Published online 2023 Apr 28. doi: 10.1126/sciadv.adg5423
PMCID:
PMC10146900
AbstractArticlePDF–2.3M
5.
IL-20 subfamily cytokines impair the oesophageal epithelial barrier by diminishing filaggrin in eosinophilic oesophagitis
Tanay Kaymak, Berna Kaya, Philipp Wuggenig, Sandro Nuciforo, Andreas Göldi, Swiss EoE Cohort Study Group (SEECS), Franz Oswald, Julien Roux, Mario Noti, Hassan Melhem, Petr Hruz, Jan Hendrik Niess
Gut. 2023 May; 72(5): 821–833. Published online 2022 May 24. doi: 10.1136/gutjnl-2022-327166
PMCID:
PMC10086458
AbstractArticlePDF–20M
6.
Streptococcus pyogenes upregulates arginine catabolism to exert its pathogenesis on the skin surface
Yujiro Hirose, Masaya Yamaguchi, Tomoko Sumitomo, Masanobu Nakata, Tomoki Hanada, Daisuke Okuzaki, Daisuke Motooka, Yasushi Mori, Hiroshi Kawasaki, Alison Coady, Satoshi Uchiyama, Masanobu Hiraoka, Raymond H. Zurich, Masayuki Amagai, Victor Nizet, Shigetada Kawabata
Cell Rep. Author manuscript; available in PMC 2022 Jun 22.
Published in final edited form as: Cell Rep. 2021 Mar 30; 34(13): 108924. doi: 10.1016/j.celrep.2021.108924
PMCID:
PMC9214650
AbstractArticlePDF–1.0M
7.
Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia
Ann-Helen Rosendahl, Mia Monnius, Anu Laitala, Antti Railo, Ilkka Miinalainen, Ritva Heljasvaara, Joni M. Mäki, Johanna Myllyharju
J Biol Chem. 2022 Apr; 298(4): 101787. Published online 2022 Mar 2. doi: 10.1016/j.jbc.2022.101787
PMCID:
PMC8988008
AbstractArticlePDF–6.1M
8.
Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor
Lisa M. Godsel, Quinn R. Roth-Carter, Jennifer L. Koetsier, Lam C. Tsoi, Amber L. Huffine, Joshua A. Broussard, Gillian N. Fitz, Sarah M. Lloyd, Junghun Kweon, Hope E. Burks, Marihan Hegazy, Saki Amagai, Paul W. Harms, Xianying Xing, Joseph Kirma, Jodi L. Johnson, Gloria Urciuoli, Lynn T. Doglio, William R. Swindell, Rajeshwar Awatramani, Eli Sprecher, Xiaomin Bao, Eran Cohen-Barak, Caterina Missero, Johann E. Gudjonsson, Kathleen J. Green
J Clin Invest. 2022 Feb 1; 132(3): e144363. Published online 2022 Feb 1. doi: 10.1172/JCI144363
PMCID:
PMC8803337
AbstractArticlePDF–3.6M
9.
The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation
Emma Carley, Rachel M Stewart, Abigail Zieman, Iman Jalilian, Diane E King, Amanda Zubek, Samantha Lin, Valerie Horsley, Megan C King
eLife. 2021; 10: e58541. Published online 2021 Mar 29. doi: 10.7554/eLife.58541
PMCID:
PMC8051949
AbstractArticlePDF–8.3M
10.
Epidermal Acyl-CoA-binding protein is indispensable for systemic energy homeostasis
Ditte Neess, Vibeke Kruse, Ann-Britt Marcher, Mie Rye Wæde, Julie Vistisen, Pauline M. Møller, Rikke Petersen, Jonathan R. Brewer, Tao Ma, Georgia Colleluori, Ilenia Severi, Saverio Cinti, Zach Gerhart-Hines, Susanne Mandrup, Nils J. Færgeman
Mol Metab. 2021 Feb; 44: 101144. Published online 2020 Dec 18. doi: 10.1016/j.molmet.2020.101144
PMCID:
PMC7797911
AbstractArticlePDF–2.3M
11.
m6A RNA methylation impacts fate choices during skin morphogenesis
Linghe Xi, Thomas Carroll, Irina Matos, Ji-Dung Luo, Lisa Polak, H Amalia Pasolli, Samie R Jaffrey, Elaine Fuchs
eLife. 2020; 9: e56980. Published online 2020 Aug 26. doi: 10.7554/eLife.56980
PMCID:
PMC7535931
AbstractArticlePDF–11M
12.
Suprabasin-null mice retain skin barrier function and show high contact hypersensitivity to nickel upon oral nickel loading
Shinsuke Nakazawa, Takatoshi Shimauchi, Atsuko Funakoshi, Masahiro Aoshima, Pawit Phadungsaksawasdi, Jun-ichi Sakabe, Sanki Asakawa, Noriyasu Hirasawa, Taisuke Ito, Yoshiki Tokura
Sci Rep. 2020; 10: 14559. Published online 2020 Sep 3. doi: 10.1038/s41598-020-71536-3
PMCID:
PMC7471289
AbstractArticlePDF–2.8M
13.
HDAC3 ensures stepwise epidermal stratification via NCoR/SMRT-reliant mechanisms independent of its histone deacetylase activity
Katherine M. Szigety, Fang Liu, Chase Y. Yuan, Deborah J. Moran, Jeremy Horrell, Heather R. Gochnauer, Ronald N. Cohen, Jonathan P. Katz, Klaus H. Kaestner, John T. Seykora, John W. Tobias, Mitchell A. Lazar, Mingang Xu, Sarah E. Millar
Genes Dev. 2020 Jul 1; 34(13-14): 973–988. doi: 10.1101/gad.333674.119
PMCID:
PMC7328513
AbstractArticlePDF–22M
14.
The Barrier Molecules Junction Plakoglobin, Filaggrin, and Dystonin Play Roles in Melanoma Growth and Angiogenesis
Katie M. Leick, Anthony B. Rodriguez, Marit M. Melssen, Mouadh Benamar, Robin S. Lindsay, Rebeka Eki, Kang-Ping Du, Mahmut Parlak, Tarek Abbas, Victor H. Engelhard, Craig L. Slingluff, Jr.
Ann Surg. Author manuscript; available in PMC 2020 May 8.
Published in final edited form as: Ann Surg. 2019 Oct; 270(4): 712–722. doi: 10.1097/SLA.0000000000003522
PMCID:
PMC7206226
AbstractArticlePDF–1.4M
15.
Chaenomeles sinensis Koehne extract suppresses the development of atopic dermatitis-like lesions by regulating cytokine and filaggrin expression in NC/Nga mice
Kyung-Jae Cha, Chang-Seob Song, Ji-Sook Lee, Ayesha Kashif, Min Hwa Hong, Geunyeong Kim, In Sik Kim
Int J Med Sci. 2019; 16(12): 1604–1613. Published online 2019 Nov 8. doi: 10.7150/ijms.37854
PMCID:
PMC6909810
AbstractArticlePDF–1.7M
16.
Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands
Lizhi Wu, Olga V. Belyaeva, Mark K. Adams, Alla V. Klyuyeva, Seung-Ah Lee, Kelli R. Goggans, Robert A. Kesterson, Kirill M. Popov, Natalia Y. Kedishvili
J Biol Chem. 2019 Nov 8; 294(45): 17060–17074. Published online 2019 Sep 27. doi: 10.1074/jbc.RA119.010835
PMCID:
PMC6851290
AbstractArticlePDF–3.5M
17.
Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL‐1β
Christian Schwartz, Tara Moran, Sean P. Saunders, Agnieszka Kaszlikowska, Achilleas Floudas, Joana Bom, Gabriel Nunez, Yoichiro Iwakura, Luke O’Neill, Alan D. Irvine, Andrew N. J. McKenzie, Graham Ogg, Patrick T. Walsh, Jocelyne Demengeot, Padraic G. Fallon
Allergy. 2019 Oct; 74(10): 1920–1933. Published online 2019 Apr 29. doi: 10.1111/all.13801
PMCID:
PMC6850072
AbstractArticlePDF–1.5M
18.
SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair
Qi Miao, Matthew C. Hill, Fengju Chen, Qianxing Mo, Amy T. Ku, Carlos Ramos, Elisabeth Sock, Véronique Lefebvre, Hoang Nguyen
Nat Commun. 2019; 10: 4042. Published online 2019 Sep 6. doi: 10.1038/s41467-019-11880-9
PMCID:
PMC6731344
AbstractArticlePDF–5.1M
19.
Distinct modes of cell competition shape mammalian tissue morphogenesis
Stephanie J. Ellis, Nicholas C. Gomez, John Levorse, Aaron F. Mertz, Yejing Ge, Elaine Fuchs
Nature. Author manuscript; available in PMC 2019 Nov 15.
Published in final edited form as: Nature. 2019 May; 569(7757): 497–502. Published online 2019 May 15. doi: 10.1038/s41586-019-1199-y
PMCID:
PMC6638572
AbstractArticlePDF–7.6M
20.
Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma
Abigail G Zieman, Brian G Poll, Jingqun Ma, Pierre A Coulombe
Hum Mol Genet. 2019 Jul 1; 28(13): 2255–2270. Published online 2019 Mar 20. doi: 10.1093/hmg/ddz050
PMCID:
PMC6602407
AbstractArticlePDF–3.5M

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