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Items: 1 to 20 of 2220

1.
A MyD88/IL-1R axis regulates PD-1 expression on tumor-associated macrophages and sustains their immunosuppressive function in melanoma
Sarang Tartey, Geoffrey Neale, Peter Vogel, R.K. Subbarao Malireddi, Thirumala-Devi Kanneganti
Cancer Res. Author manuscript; available in PMC 2024 Dec 13.
Published in final edited form as: Cancer Res. 2021 May 1; 81(9): 2358–2372. Published online 2021 Feb 22. doi: 10.1158/0008-5472.CAN-20-3510
PMCID:
PMC11645125
AbstractArticlePDF–3.4M
2.
CDS2 expression regulates de novo phosphatidic acid synthesis
Daniel M. Collins, Vishnu Janardan, David Barneda, Karen E. Anderson, Izabella Niewczas, Diane Taylor, Danye Qiu, Henning J. Jessen, Andrea F. Lopez-Clavijo, Simon Walker, Padinjat Raghu, Jonathan Clark, Len R. Stephens, Phillip T. Hawkins
Biochem J. 2024 Oct 16; 481(20): 1449–1473. Published online 2024 Oct 11. doi: 10.1042/BCJ20240456
PMCID:
PMC11555650
AbstractArticlePDF–8.4M
3.
The protein segregase VCP/p97 promotes host antifungal defense via regulation of SYK activation
Zhugui Shao, Li Wang, Limin Cao, Tian Chen, Xin-Ming Jia, Wanwei Sun, Chengjiang Gao, Hui Xiao
PLoS Pathog. 2024 Oct; 20(10): e1012674. Published online 2024 Oct 29. doi: 10.1371/journal.ppat.1012674
PMCID:
PMC11548748
AbstractArticlePDF–2.2M
4.
Stored RBC Transfusions Leads to the Systemic Inflammatory Response Syndrome in Anemic Murine Neonates
Balamurugan Ramatchandirin, Marie Amalie Balamurugan, Suneetha Desiraju, Yerin Chung, Boguslaw S. Wojczyk, Krishnan MohanKumar
Inflamm Res. Author manuscript; available in PMC 2024 Nov 7.
Published in final edited form as: Inflamm Res. 2024 Nov; 73(11): 1859–1873. Published online 2024 Sep 5. doi: 10.1007/s00011-024-01936-y
PMCID:
PMC11540732
AbstractArticlePDF–1.8M
5.
The STAT3/SETDB2 axis dictates NF-κB–mediated inflammation in macrophages during wound repair
Kevin D. Mangum, Aaron denDekker, Qinmengge Li, Lam C. Tsoi, Amrita D. Joshi, William J. Melvin, Sonya J. Wolf, Jadie Y. Moon, Christopher O. Audu, James Shadiow, Andrea T. Obi, Rachael Wasikowski, Emily C. Barrett, Tyler M. Bauer, Kylie Boyer, Zara Ahmed, Frank M. Davis, Johann Gudjonsson, Katherine A. Gallagher
JCI Insight. 2024 Oct 22; 9(20): e179017. Published online 2024 Oct 22. doi: 10.1172/jci.insight.179017
PMCID:
PMC11530128
AbstractArticlePDF–2.4M
6.
N-acetyltransferase 10 is implicated in the pathogenesis of cycling T cell-mediated autoimmune and inflammatory disorders in mice
Wen-ping Li, Xin-tao Mao, Jia-huan Xie, Jie-yu Li, Bao-qin Liu, Le-xi Wu, Bing Yang, Yi-yuan Li, Jin Jin
Nat Commun. 2024; 15: 9388. Published online 2024 Oct 30. doi: 10.1038/s41467-024-53350-x
PMCID:
PMC11525920
AbstractArticlePDF–4.6M
7.
Glucose metabolism controls monocyte homeostasis and migration but has no impact on atherosclerosis development in mice
Alexandre Gallerand, Bastien Dolfi, Marion I. Stunault, Zakariya Caillot, Alexia Castiglione, Axelle Strazzulla, Chuqiao Chen, Gyu Seong Heo, Hannah Luehmann, Flora Batoul, Nathalie Vaillant, Adélie Dumont, Thomas Pilot, Johanna Merlin, Fairouz N. Zair, Jerome Gilleron, Adeline Bertola, Peter Carmeliet, Jesse W. Williams, Rafael J. Arguello, David Masson, David Dombrowicz, Laurent Yvan-Charvet, Denis Doyen, Arvand Haschemi, Yongjian Liu, Rodolphe R. Guinamard, Stoyan Ivanov
Nat Commun. 2024; 15: 9027. Published online 2024 Oct 19. doi: 10.1038/s41467-024-53267-5
PMCID:
PMC11489573
AbstractArticlePDF–3.4M
8.
Deleting autotaxin in LysM+ myeloid cells impairs innate tumor immunity in models of metastatic melanoma
Mélanie A. Dacheux, Derek D. Norman, Yoojin Shin, Gábor J. Tigyi, Sue Chin Lee
iScience. 2024 Oct 18; 27(10): 110971. Published online 2024 Sep 17. doi: 10.1016/j.isci.2024.110971
PMCID:
PMC11467674
AbstractArticlePDF–7.2M
9.
Macrophage-mediated myelin recycling fuels brain cancer malignancy
Daan J. Kloosterman, Johanna Erbani, Menno Boon, Martina Farber, Shanna M. Handgraaf, Masami Ando-Kuri, Elena Sánchez-López, Bauke Fontein, Marjolijn Mertz, Marja Nieuwland, Ning Qing Liu, Gabriel Forn-Cuni, Nicole N. van der Wel, Anita E. Grootemaat, Luuk Reinalda, Sander I. van Kasteren, Elzo de Wit, Brian Ruffell, Ewa Snaar-Jagalska, Kevin Petrecca, Dieta Brandsma, Alexander Kros, Martin Giera, Leila Akkari
Cell. 2024 Sep 19; 187(19): 5336–5356.e30. doi: 10.1016/j.cell.2024.07.030
PMCID:
PMC11429458
AbstractArticle
10.
Role of Mitofusin 1 in mediating reactive oxygen species in alveolar macrophages during Streptococcuspneumoniae
David Thomas, Jianjun Yang, Soo Jung Cho, Heather Stout-Delgado
Redox Biol. 2024 Oct; 76: 103329. Published online 2024 Aug 27. doi: 10.1016/j.redox.2024.103329
PMCID:
PMC11400614
AbstractArticlePDF–11M
11.
Vangl2 suppresses NF-κB signaling and ameliorates sepsis by targeting p65 for NDP52-mediated autophagic degradation
Jiansen Lu, Jiahuan Zhang, Huaji Jiang, Zhiqiang Hu, Yufen Zhang, Lian He, Jianwu Yang, Yingchao Xie, Dan Wu, Hongyu Li, Ke Zeng, Peng Tan, Qingyue Xiao, Zijing Song, Chenglong Pan, Xiaochun Bai, Xiao Yu
eLife. 2024; 12: RP87935. Published online 2024 Sep 13. doi: 10.7554/eLife.87935
PMCID:
PMC11398866
AbstractArticlePDF–7.8M
12.
EGR2 is an epigenomic regulator of phagocytosis and antifungal immunity in alveolar macrophages
Zsuzsanna Kolostyak, Dora Bojcsuk, Viktoria Baksa, Zsuzsa Mathene Szigeti, Krisztian Bene, Zsolt Czimmerer, Pal Boto, Lina Fadel, Szilard Poliska, Laszlo Halasz, Petros Tzerpos, Wilhelm K. Berger, Andres Villabona-Rueda, Zsofia Varga, Tunde Kovacs, Andreas Patsalos, Attila Pap, Gyorgy Vamosi, Peter Bai, Balazs Dezso, Matthew Spite, Franco R. D’Alessio, Istvan Szatmari, Laszlo Nagy
JCI Insight. 2024 Sep 10; 9(17): e164009. Published online 2024 Sep 10. doi: 10.1172/jci.insight.164009
PMCID:
PMC11385099
AbstractArticlePDF–4.6M
13.
TIM-3 on myeloid cells promotes pulmonary inflammation through increased production of galectin-3
Ki Sun Kim, Chanju Lee, Hyung-Seok Kim, Su Jeong Gu, Hee Jung Yoon, Su Bin Won, Ho Lee, Yong Sun Lee, Sang Soo Kim, Lawrence P. Kane, Eun Jung Park
Commun Biol. 2024; 7: 1090. Published online 2024 Sep 5. doi: 10.1038/s42003-024-06762-w
PMCID:
PMC11377825
AbstractArticlePDF–6.5M
14.
The Foxo1-YAP-Notch1 axis reprograms STING-mediated innate immunity in NASH progression
Dongwei Xu, Xiaoye Qu, Tao Yang, Mingwei Sheng, Xiyun Bian, Yongqiang Zhan, Yizhu Tian, Yuanbang Lin, Yuting Jin, Xiao Wang, Michael Ke, Longfeng Jiang, Changyong Li, Qiang Xia, Douglas G. Farmer, Bibo Ke
Exp Mol Med. 2024 Aug; 56(8): 1843–1855. Published online 2024 Aug 9. doi: 10.1038/s12276-024-01280-5
PMCID:
PMC11372114
AbstractArticlePDF–4.0M
15.
The involvement of peritoneal GATA6+ macrophages in the pathogenesis of endometriosis
Mingxin Shi, James A. MacLean, II, Kanako Hayashi
Front Immunol. 2024; 15: 1396000. Published online 2024 Aug 12. doi: 10.3389/fimmu.2024.1396000
PMCID:
PMC11348394
AbstractArticlePDF–10M
16.
Macrophage ILF3 promotes abdominal aortic aneurysm by inducing inflammatory imbalance in male mice
Zhao-yang Wang, Jie Cheng, Ying Wang, Hai-tao Yuan, Shao-jie Bi, Shuang-xi Wang, Ya-min Hou, Xu Zhang, Bo-han Xu, Ze-ying Wang, Yun Zhang, Wen-jian Jiang, Yu-guo Chen, Ming-xiang Zhang
Nat Commun. 2024; 15: 7249. Published online 2024 Aug 23. doi: 10.1038/s41467-024-51030-4
PMCID:
PMC11344041
AbstractArticlePDF–7.3M
17.
NADPH oxidase in B cells and macrophages protects against murine lupus by regulation of TLR7
Rachael A. Gordon, Haylee A. Cosgrove, Anthony Marinov, Sebastien Gingras, Jeremy S. Tilstra, Allison M. Campbell, Sheldon I. Bastacky, Michael Kashgarian, Andras Perl, Kevin M. Nickerson, Mark J. Shlomchik
JCI Insight. 2024 Aug 22; 9(16): e178563. Published online 2024 Jul 23. doi: 10.1172/jci.insight.178563
PMCID:
PMC11343599
AbstractArticlePDF–5.3M
18.
Cathepsin D is essential for the degradomic shift of macrophages required to resolve liver fibrosis
Paloma Ruiz-Blázquez, María Fernández-Fernández, Valeria Pistorio, Celia Martinez-Sanchez, Michele Costanzo, Paula Iruzubieta, Ekaterina Zhuravleva, Júlia Cacho-Pujol, Silvia Ariño, Alejandro Del Castillo-Cruz, Susana Núñez, Jesper B. Andersen, Margherita Ruoppolo, Javier Crespo, Carmen García-Ruiz, Luigi Michele Pavone, Thomas Reinheckel, Pau Sancho-Bru, Mar Coll, José C. Fernández-Checa, Anna Moles
Mol Metab. 2024 Sep; 87: 101989. Published online 2024 Jul 15. doi: 10.1016/j.molmet.2024.101989
PMCID:
PMC11327474
AbstractArticlePDF–5.2M
19.
Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice
Jeremy M. Sullivan, Anna M. Bagnell, Jonathan Alevy, Elvia Mena Avila, Ljubica Mihaljević, Pamela C. Saavedra-Rivera, Lingling Kong, Jennifer S. Huh, Brett A. McCray, William H. Aisenberg, Aamir R. Zuberi, Laurent Bogdanik, Cathleen M. Lutz, Zhaozhu Qiu, Katharina A. Quinlan, Peter C. Searson, Charlotte J. Sumner
Sci Transl Med. Author manuscript; available in PMC 2024 Aug 10.
Published in final edited form as: Sci Transl Med. 2024 May 22; 16(748): eadk1358. Published online 2024 May 22. doi: 10.1126/scitranslmed.adk1358
PMCID:
PMC11316273
AbstractArticlePDF–2.3M
20.
Signaling through the nicotinic acetylcholine receptor in the liver protects against the development of metabolic dysfunction-associated steatohepatitis
Heejin Jun, Shanshan Liu, Alexander J. Knights, Kezhou Zhu, Yingxu Ma, Jianke Gong, Ashley E. Lenhart, Xiaoling Peng, Yunying Huang, Jared P. Ginder, Christopher H. Downie, Erika Thalia Ramos, Klas Kullander, Robert T. Kennedy, X. Z. Shawn Xu, Jun Wu
PLoS Biol. 2024 Jul; 22(7): e3002728. Published online 2024 Jul 19. doi: 10.1371/journal.pbio.3002728
PMCID:
PMC11290650
AbstractArticlePDF–3.0M

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