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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107024732.

Targeting collagen XVIII improves the efficiency of ErbB inhibitors in breast cancer models

Raman Devarajan, Valerio Izzi, Hellevi Peltoketo, Gunilla Rask, Saila Kauppila, Marja-Riitta Väisänen, Heli Ruotsalainen, Guillermo Martínez-Nieto, Sanna-Maria Karppinen, Timo Väisänen, Inderjeet Kaur, Jussi Koivunen, Takako Sasaki, Robert Winqvist, Aki Manninen, Fredrik Wärnberg, Malin Sund, Taina Pihlajaniemi, Ritva Heljasvaara

J Clin Invest. 2023 Sep 15; 133(18): e159181. Published online 2023 Sep 15. doi: 10.1172/JCI159181

PMCID:: PMC10702473

Abstract Article PDF–8.8M

Select item 102165873.

Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis

Tayler F. L. Wishart, Frank J. Lovicu

Cells. 2023 May; 12(10): 1364. Published online 2023 May 11. doi: 10.3390/cells12101364

PMCID:: PMC10216587

Abstract Article PDF–20M

Select item 101771504.

Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin

Valentina Castillo, Pamela Díaz-Astudillo, Rocío Corrales-Orovio, Sebastián San Martín, José Tomás Egaña

Cells. 2023 May; 12(9): 1215. Published online 2023 Apr 22. doi: 10.3390/cells12091215

PMCID:: PMC10177150

Abstract Article PDF–3.4M

Select item 83132395.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79572656.

FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex

Chen Zhou, Danying Chen, Jianhan Ren, Delan Huang, Runze Li, Haotian Luo, Chenyu Guan, Yang Cao, Weicai Wang

J Cell Mol Med. 2021 Mar; 25(6): 3051–3062. Published online 2021 Feb 13. doi: 10.1111/jcmm.16351

PMCID:: PMC7957265

Abstract Article PDF–2.4M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78384188.

Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract

Rupalatha Maddala, Junyuan Gao, Richard T. Mathias, Tylor R. Lewis, Vadim Y. Arshavsky, Adriana Levine, Jonathan M. Backer, Anne R. Bresnick, Ponugoti V. Rao

Sci Rep. 2021; 11: 2203. Published online 2021 Jan 26. doi: 10.1038/s41598-021-81611-y

PMCID:: PMC7838418

Abstract Article PDF–6.5M

Select item 72939249.

The Spatiotemporal Expression Pattern of Syndecans in Murine Embryonic Teeth

Jingyi Wu, Hong Li, Lu Han, Tianyu Sun, Ye Tian, Xiaofang Wang

Gene Expr Patterns. Author manuscript; available in PMC 2021 Jun 1.

Published in final edited form as: Gene Expr Patterns. 2020 Jun; 36: 119109. Published online 2020 Mar 24. doi: 10.1016/j.gep.2020.119109

PMCID:: PMC7293924

Abstract Article PDF–1.2M

Select item 709906610.

The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche

Dalya Ataca, Patrick Aouad, Céline Constantin, Csaba Laszlo, Manfred Beleut, Marie Shamseddin, Renuga Devi Rajaram, Rachel Jeitziner, Timothy J. Mead, Marian Caikovski, Philipp Bucher, Giovanna Ambrosini, Suneel S. Apte, Cathrin Brisken

Nat Commun. 2020; 11: 1571. Published online 2020 Mar 26. doi: 10.1038/s41467-020-15357-y

PMCID:: PMC7099066

Abstract Article PDF–5.8M

Select item 599259611.

Collagen 18 and agrin are secreted by neural crest cells to remodel their microenvironment and regulate their migration during enteric nervous system development

Nandor Nagy, Csilla Barad, Ryo Hotta, Sukhada Bhave, Emily Arciero, David Dora, Allan M. Goldstein

Development. 2018 May 1; 145(9): dev160317. Published online 2018 May 8. doi: 10.1242/dev.160317

PMCID:: PMC5992596

Abstract Article

Select item 550326112.

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program

John P. Sundberg, Soheil S. Dadras, Kathleen A. Silva, Victoria E. Kennedy, Gaven Garland, Stephen A. Murray, Beth A. Sundberg, Paul N. Schofield, C. Herbert Pratt

PLoS One. 2017; 12(7): e0180682. Published online 2017 Jul 10. doi: 10.1371/journal.pone.0180682

PMCID:: PMC5503261

Abstract Article PDF–31M

Select item 529582113.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 522315914.

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression

Alexandra Naba, Karl R. Clauser, D. R. Mani, Steven A. Carr, Richard O. Hynes

Sci Rep. 2017; 7: 40495. Published online 2017 Jan 10. doi: 10.1038/srep40495

PMCID:: PMC5223159

Abstract Article PDF–2.3M

Select item 486866415.

Endostatin and transglutaminase 2 are involved in fibrosis of the aging kidney

Chi Hua Sarah Lin, Jun Chen, Zhongtao Zhang, Gail Johnson, Arthur JL Cooper, Julianne Feola, Alexander Bank, Jonathan Shein, Heli Ruotsalainen, Taina Pihlajaniemi, Michael S Goligorsky

Kidney Int. Author manuscript; available in PMC 2017 Jun 1.

Published in final edited form as: Kidney Int. 2016 Jun; 89(6): 1281–1292. Published online 2016 Apr 14. doi: 10.1016/j.kint.2016.01.030

PMCID:: PMC4868664

Abstract Article PDF–2.0M

Select item 465405216.

Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation

Gayle B. Collin, Dirk Hubmacher, Jeremy R. Charette, Wanda L. Hicks, Lisa Stone, Minzhong Yu, Jürgen K. Naggert, Mark P. Krebs, Neal S. Peachey, Suneel S. Apte, Patsy M. Nishina

Hum Mol Genet. 2015 Dec 15; 24(24): 6958–6974. Published online 2015 Sep 24. doi: 10.1093/hmg/ddv399

PMCID:: PMC4654052

Abstract Article PDF–1.7M

Select item 440953017.

Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis

Tatiana Y. Besschetnova, Takaharu Ichimura, Negin Katebi, Brad St. Croix, Joseph V. Bonventre, Bjorn R. Olsen

Matrix Biol. Author manuscript; available in PMC 2016 Mar 1.

Published in final edited form as: Matrix Biol. 2015 Mar; 42: 56–73. Published online 2015 Jan 5. doi: 10.1016/j.matbio.2014.12.002

PMCID:: PMC4409530

Abstract Article PDF–3.4M

Select item 431955918.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 422236119.

Neural deletion of Tgfbr2 impairs angiogenesis through an altered secretome

Nicole Hellbach, Stefan C. Weise, Riccardo Vezzali, Shalaka D. Wahane, Stefanie Heidrich, Deborah Roidl, Jan Pruszak, Jennifer S. Esser, Tanja Vogel

Hum Mol Genet. 2014 Dec 1; 23(23): 6177–6190. Published online 2014 Jul 2. doi: 10.1093/hmg/ddu338

PMCID:: PMC4222361

Abstract Article PDF–1.4M

Select item 415475320.

Basement Membrane Zone Collagens XV and XVIII/Proteoglycans Mediate Leukocyte Influx in Renal Ischemia/Reperfusion

Azadeh Zaferani, Ditmer T. Talsma, Saleh Yazdani, Johanna W. A. M. Celie, Mari Aikio, Ritva Heljasvaara, Gerjan J. Navis, Taina Pihlajaniemi, Jacob van den Born

PLoS One. 2014; 9(9): e106732. Published online 2014 Sep 4. doi: 10.1371/journal.pone.0106732

PMCID:: PMC4154753

Abstract Article PDF–13M

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