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Select item 113617161.

A Genome-Wide CRISPR Screen Identifies BRD4 as a Regulator of Cardiomyocyte Differentiation

Arun Padmanabhan, Yvanka de Soysa, Angelo Pelonero, Valerie Sapp, Parisha P. Shah, Qiaohong Wang, Li Li, Clara Youngna Lee, Nandhini Sadagopan, Tomohiro Nishino, Lin Ye, Rachel Yang, Ashley Karnay, Andrey Poleshko, Nikhita Bolar, Ricardo Linares-Saldana, Sanjeev S. Ranade, Michael Alexanian, Sarah U. Morton, Mohit Jain, Saptarsi M. Haldar, Deepak Srivastava, Rajan Jain

Nat Cardiovasc Res. Author manuscript; available in PMC 2024 Aug 29.

Published in final edited form as: Nat Cardiovasc Res. 2024 Mar; 3(3): 317–331. Published online 2024 Feb 23. doi: 10.1038/s44161-024-00431-1

PMCID:: PMC11361716

Abstract Article PDF–8.1M

Select item 110892532.

Msx genes delineate a novel molecular map of the developing cerebellar neuroepithelium

Ishita Gupta, Joanna Yeung, Maryam Rahimi-Balaei, Sih-Rong Wu, Dan Goldowitz

Front Mol Neurosci. 2024; 17: 1356544. Published online 2024 Apr 29. doi: 10.3389/fnmol.2024.1356544

PMCID:: PMC11089253

Abstract Article PDF–19M

Select item 108842403.

Loss of Neogenin alters branchial arch development and leads to craniofacial skeletal defects

Sabrina Quilez, Emilie Dumontier, Christopher Baim, Joseph Kam, Jean-François Cloutier

Front Cell Dev Biol. 2024; 12: 1256465. Published online 2024 Feb 9. doi: 10.3389/fcell.2024.1256465

PMCID:: PMC10884240

Abstract Article PDF–6.8M

Select item 108619094.

Streamlined identification of clinically and functionally relevant genetic regulators of lower-tract urogenital development

Meade Haller, Yan Yin, Gabe Haller, Tian Li, Qiufang Li, Laura E. Lamb, Liang Ma

Proc Natl Acad Sci U S A. 2024 Feb 6; 121(6): e2309466121. Published online 2024 Feb 1. doi: 10.1073/pnas.2309466121

PMCID:: PMC10861909

Abstract Article PDF–2.9M

Select item 106629725.

Myocardial equation M1

-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation

Yidong Wang, Pengfei Lu, Bingruo Wu, Dario F. Riascos-Bernal, Nicholas E.S. Sibinga, Tomas Valenta, Konrad Basler, Bin Zhou

J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Nov 21.

Published in final edited form as: J Mol Cell Cardiol. 2018 Oct; 123: 150–158. Published online 2018 Sep 8. doi: 10.1016/j.yjmcc.2018.09.001

PMCID:: PMC10662972

Abstract Article PDF–2.2M

Select item 106559186.

The transcription factors Foxf1 and Foxf2 integrate the SHH, HGF and TGFβ signaling pathways to drive tongue organogenesis

Jingyue Xu, Han Liu, Yu Lan, Rulang Jiang

Development. 2022 Nov 1; 149(21): dev200667. Published online 2022 Oct 28. doi: 10.1242/dev.200667

PMCID:: PMC10655918

Abstract Article

Select item 105925427.

Enam expression is regulated by Msx2

Intan Ruspita, Pragnya Das, Keiko Miyoshi, Takafumi Noma, Malcolm L. Snead, Marianna Bei

Dev Dyn. Author manuscript; available in PMC 2024 Oct 1.

Published in final edited form as: Dev Dyn. 2023 Oct; 252(10): 1292–1302. Published online 2023 May 16. doi: 10.1002/dvdy.598

PMCID:: PMC10592542

Abstract Article PDF–1.1M

Select item 105473008.

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development

Bingruo Wu, Brian Wu, Sonia Benkaci, Lijie Shi, Pengfei Lu, Taeju Park, Bernice E. Morrow, Yidong Wang, Bin Zhou

J Am Heart Assoc. 2023 Sep 19; 12(18): e029683. Published online 2023 Sep 13. doi: 10.1161/JAHA.123.029683

PMCID:: PMC10547300

Abstract Article PDF–41M

Select item 103904929.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 1031092910.

β-Catenin regulates endocardial cushion growth by suppressing p21

Huahua Liu, Pengfei Lu, Shan He, Yuru Luo, Yuan Fang, Sonia Benkaci, Bingruo Wu, Yidong Wang, Bin Zhou

Life Sci Alliance. 2023 Sep; 6(9): e202302163. Published online 2023 Jun 29. doi: 10.26508/lsa.202302163

PMCID:: PMC10310929

Abstract Article PDF–4.2M

Select item 1016334911.

Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes

Yushi Redhead, Dorota Gibbins, Eva Lana-Elola, Sheona Watson-Scales, Lisa Dobson, Matthias Krause, Karen J. Liu, Elizabeth M. C. Fisher, Jeremy B. A. Green, Victor L. J. Tybulewicz

Development. 2023 Apr 15; 150(8): dev201077. Published online 2023 Apr 26. doi: 10.1242/dev.201077

PMCID:: PMC10163349

Abstract Article

Select item 1002785512.

Single-cell transcriptomics uncovers a non-autonomous Tbx1-dependent genetic program controlling cardiac neural crest cell development

Christopher De Bono, Yang Liu, Alexander Ferrena, Aneesa Valentine, Deyou Zheng, Bernice E. Morrow

Nat Commun. 2023; 14: 1551. Published online 2023 Mar 21. doi: 10.1038/s41467-023-37015-9

PMCID:: PMC10027855

Abstract Article PDF–19M

Select item 1002055913.

A differentiation roadmap of murine placentation at single-cell resolution

Xiangxiang Jiang, Yue Wang, Zhenyu Xiao, Long Yan, Shanshan Guo, Yiming Wang, Hao Wu, Xuehan Zhao, Xiaoyin Lu, Hongmei Wang

Cell Discov. 2023; 9: 30. Published online 2023 Mar 17. doi: 10.1038/s41421-022-00513-z

PMCID:: PMC10020559

Abstract Article PDF–5.8M

Select item 959521114.

Single-cell atlas of craniogenesis uncovers SOXC-dependent, highly proliferative, and myofibroblast-like osteodermal progenitors

Marco Angelozzi, Renata Pellegrino da Silva, Michael V. Gonzalez, Véronique Lefebvre

Cell Rep. Author manuscript; available in PMC 2022 Oct 25.

Published in final edited form as: Cell Rep. 2022 Jul 12; 40(2): 111045. doi: 10.1016/j.celrep.2022.111045

PMCID:: PMC9595211

Abstract Article PDF–4.7M

Select item 955395115.

Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming

Danyang Chong, Yayun Gu, Tongyu Zhang, Yu Xu, Dandan Bu, Zhong Chen, Na Xu, Liangkui Li, Xiyu Zhu, Haiquan Wang, Yangqing Li, Feng Zheng, Dongjin Wang, Peng Li, Li Xu, Zhibin Hu, Chaojun Li

Cell Discov. 2022; 8: 106. Published online 2022 Oct 11. doi: 10.1038/s41421-022-00447-6

PMCID:: PMC9553951

Abstract Article PDF–3.8M

Select item 938289816.

Single-cell transcriptomic signatures and gene regulatory networks modulated by Wls in mammalian midline facial formation and clefts

Ran Gu, Shuwen Zhang, Subbroto Kumar Saha, Yu Ji, Kurt Reynolds, Moira McMahon, Bo Sun, Mohammad Islam, Paul A. Trainor, YiPing Chen, Ying Xu, Yang Chai, Diana Burkart-Waco, Chengji J. Zhou

Development. 2022 Jul 15; 149(14): dev200533. Published online 2022 Jul 22. doi: 10.1242/dev.200533

PMCID:: PMC9382898

Abstract Article

Select item 923587517.

Snrpb is required in murine neural crest cells for proper splicing and craniofacial morphogenesis

Sabrina Shameen Alam, Shruti Kumar, Marie-Claude Beauchamp, Eric Bareke, Alexia Boucher, Nadine Nzirorera, Yanchen Dong, Reinnier Padilla, Si Jing Zhang, Jacek Majewski, Loydie A. Jerome-Majewska

Dis Model Mech. 2022 Jun 1; 15(6): dmm049544. Published online 2022 Jun 23. doi: 10.1242/dmm.049544

PMCID:: PMC9235875

Abstract Article

Select item 907069218.

A Neural Crest-specific Overexpression Mouse Model Reveals the Transcriptional Regulatory Effects of Dlx2 During Maxillary Process Development

Jian Sun, NaYoung Ha, Zhixu Liu, Qian Bian, Xudong Wang

Front Physiol. 2022; 13: 855959. Published online 2022 Apr 21. doi: 10.3389/fphys.2022.855959

PMCID:: PMC9070692

Abstract Article PDF–5.6M

Select item 879402319.

BMP4 and Wnt signaling interact to promote mouse tracheal mesenchyme morphogenesis

Natalia Bottasso-Arias, Lauren Leesman, Kaulini Burra, John Snowball, Ronak Shah, Megha Mohanakrishnan, Yan Xu, Debora Sinner

Am J Physiol Lung Cell Mol Physiol. 2022 Feb 1; 322(2): L224–L242. Published online 2021 Dec 1. doi: 10.1152/ajplung.00255.2021

PMCID:: PMC8794023

Abstract Article

Select item 871407620.

SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning

Julie Gamart, Iros Barozzi, Frédéric Laurent, Robert Reinhardt, Laurène Ramos Martins, Thomas Oberholzer, Axel Visel, Rolf Zeller, Aimée Zuniga

Development. 2021 Dec 1; 148(23): dev200182. Published online 2021 Dec 3. doi: 10.1242/dev.200182

PMCID:: PMC8714076

Abstract Article

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