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Items: 1 to 20 of 44

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Rnd3 suppresses endothelial cell pyroptosis in atherosclerosis through regulation of ubiquitination of TRAF6
Yan Zhang, Zhengru Zhu, Yang Cao, Zhenyu Xiong, Yu Duan, Jie Lin, Xuebin Zhang, Mengyuan Jiang, Yue Liu, Wanrong Man, Tengfei Jia, Jiaxu Feng, Yanyan Chen, Congye Li, Baolin Guo, Dongdong Sun
Clin Transl Med. 2023 Sep; 13(9): e1406. Published online 2023 Sep 24. doi: 10.1002/ctm2.1406
PMCID:
PMC10518494
AbstractArticlePDF–13M
3.
Fibroblast-specific activation of Rnd3 protects against cardiac remodeling in diabetic cardiomyopathy via suppression of Notch and TGF-β signaling
Yan Zhang, Yang Cao, Rui Zheng, Zhenyu Xiong, Zhengru Zhu, Fanya Gao, Wanrong Man, Yu Duan, Jie Lin, Xuebin Zhang, Dexi Wu, Mengyuan Jiang, Xiao Zhang, Congye Li, Xiaoming Gu, Yanhong Fan, Dongdong Sun
Theranostics. 2022; 12(17): 7250–7266. Published online 2022 Oct 17. doi: 10.7150/thno.77043
PMCID:
PMC9691359
AbstractArticlePDF–5.2M
4.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
Genetic deletion of Rnd3 suppresses apoptosis through NF-κB signaling in the brain
Huimin Dong, Qian Sun, Ying Zhang, Yuntao Li, Fan'en Yuan, Shanping Mao, Baohui Liu
Oncol Rep. 2021 Feb; 45(2): 595–605. Published online 2020 Dec 8. doi: 10.3892/or.2020.7884
PMCID:
PMC7757088
AbstractArticlePDF–1.4M
7.
Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold
Navjot Kaur, Wenqi Han, Zhuo Li, M. Pilar Madrigal, Sungbo Shim, Sirisha Pochareddy, Forrest O. Gulden, Mingfeng Li, Xuming Xu, Xiaojun Xing, Yutaka Takeo, Zhen Li, Kangrong Lu, Yuka Imamura Kawasawa, Begoña Ballester-Lurbe, Juan Antonio Moreno-Bravo, Alain Chédotal, José Terrado, Ignacio Pérez-Roger, Anthony J. Koleske, Nenad Sestan
Neuron. Author manuscript; available in PMC 2021 Sep 23.
Published in final edited form as: Neuron. 2020 Sep 23; 107(6): 1197–1211.e9. Published online 2020 Jul 23. doi: 10.1016/j.neuron.2020.06.035
PMCID:
PMC7529949
AbstractArticlePDF–2.0M
8.
Binary Fate Choice between Closely Related Interneuronal Types Is Determined by A Fezf1-Dependent Postmitotic Transcriptional Switch
Yi-Rong Peng, Rebecca E. James, Wenjun Yan, Jeremy N. Kay, Alex L. Kolodkin, Joshua R. Sanes
Neuron. Author manuscript; available in PMC 2021 Feb 5.
Published in final edited form as: Neuron. 2020 Feb 5; 105(3): 464–474.e6. Published online 2019 Dec 4. doi: 10.1016/j.neuron.2019.11.002
PMCID:
PMC7007373
AbstractArticlePDF–2.2M
9.
Telencephalic Embryonic Subtractive Sequences: A Unique Collection of Neurodevelopmental Genes
Alessandro Bulfone, Pietro Carotenuto, Andrea Faedo, Veruska Aglio, Livia Garzia, Anna Maria Bello, Andrea Basile, Alessandra Andrè, Massimo Cocchia, Ombretta Guardiola, Andrea Ballabio, John L. R. Rubenstein, Massimo Zollo
J Neurosci. 2005 Aug 17; 25(33): 7586–7600. doi: 10.1523/JNEUROSCI.0522-05.2005
PMCID:
PMC6725394
AbstractArticlePDF–682K
10.
RhoE fine-tunes inflammatory response in myocardial infarction
Yuan Dai, Jiangping Song, Wenjiao Li, Tingli Yang, Xiaojing Yue, Xi Lin, Xiangsheng Yang, Weijia Luo, Junli Guo, Xin Wang, Songqing Lai, Kelsey C. Andrade, Jiang Chang
Circulation. Author manuscript; available in PMC 2020 Feb 26.
Published in final edited form as: Circulation. 2019 Feb 26; 139(9): 1185–1198. doi: 10.1161/CIRCULATIONAHA.118.033700
PMCID:
PMC6532428
AbstractArticlePDF–1.3M
11.
The atypical RhoGTPase RhoE/Rnd3 is a key molecule to acquire a neuroprotective phenotype in microglia
Veronika E. Neubrand, Irene Forte-Lago, Marta Caro, Mario Delgado
J Neuroinflammation. 2018; 15: 343. Published online 2018 Dec 15. doi: 10.1186/s12974-018-1386-z
Correction in:
J Neuroinflammation. 2019; 16: 31.
PMCID:
PMC6295018
AbstractArticlePDF–2.6M
12.
Genetic deletion of Rnd3 in neural stem cells promotes proliferation via upregulation of Notch signaling
Huimin Dong, Xi Lin, Yuntao Li, Ronghua Hu, Yang Xu, Xiaojie Guo, Qiong La, Shun Wang, Congcong Fang, Junli Guo, Qi Li, Shanping Mao, Baohui Liu
Oncotarget. 2017 Oct 31; 8(53): 91112–91122. Published online 2017 Aug 14. doi: 10.18632/oncotarget.20247
PMCID:
PMC5710772
AbstractArticlePDF–8.6M
13.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
14.
Rnd3/RhoE Modulates HIF1α/VEGF Signaling by Stabilizing HIF1α and Regulates Responsive Cardiac Angiogenesis
Xiaojing Yue, Xi Lin, Tingli Yang, Xiangsheng Yang, Xin Yi, Xuejun Jiang, Xiaoyan Li, Tianfa Li, Junli Guo, Yuan Dai, Jianjian Shi, Lei Wei, Keith A. Youker, Guillermo Torre-Amione, Yanhong Yu, Kelsey C. Andrade, Jiang Chang
Hypertension. Author manuscript; available in PMC 2017 Mar 1.
Published in final edited form as: Hypertension. 2016 Mar; 67(3): 597–605. Published online 2016 Jan 18. doi: 10.1161/HYPERTENSIONAHA.115.06412
PMCID:
PMC4752414
AbstractArticlePDF–3.2M
15.
RhoE is required for contact inhibition and negatively regulates tumor initiation and progression
Marta Hernández-Sánchez, Enric Poch, Rosa M. Guasch, Joaquín Ortega, Inmaculada López-Almela, Ignacio Palmero, Ignacio Pérez-Roger
Oncotarget. 2015 Jul 10; 6(19): 17479–17490. Published online 2015 May 12. doi: 10.18632/oncotarget.4127
PMCID:
PMC4627322
AbstractArticlePDF–1.3M
16.
Rnd3 haploinsufficient mice are predisposed to hemodynamic stress and develop apoptotic cardiomyopathy with heart failure
X Yue, X Yang, X Lin, T Yang, X Yi, Y Dai, J Guo, T Li, J Shi, L Wei, G-C Fan, C Chen, J Chang
Cell Death Dis. 2014 Jun; 5(6): e1284. Published online 2014 Jun 5. doi: 10.1038/cddis.2014.235
PMCID:
PMC4611712
AbstractArticlePDF–1.8M
17.
Genetic Deletion of Rnd3/RhoE Results in Mouse Heart Calcium Leakage Through Upregulation of Protein Kinase A Signaling
Xiangsheng Yang, Tiannan Wang, Xi Lin, Xiaojing Yue, Qiongling Wang, Guoliang Wang, Qin Fu, Xun Ai, David Y. Chiang, Christina Y. Miyake, Xander H.T. Wehrens, Jiang Chang
Circ Res. Author manuscript; available in PMC 2016 Jan 2.
Published in final edited form as: Circ Res. 2015 Jan 2; 116(1): e1–e10. Published online 2014 Oct 27. doi: 10.1161/CIRCRESAHA.116.304940
PMCID:
PMC4282622
AbstractArticlePDF–3.1M
18.
Analysis of RhoE expression in the testis, epididymis and ductus deferens, and the effects of its deficiency in mice
Olga Gómez, Begoña Ballester-Lurbe, Rosa M Guasch, Ignacio Pérez-Roger, Empar García-Roselló, José Terrado
J Anat. 2014 Dec; 225(6): 583–590. Published online 2014 Oct 1. doi: 10.1111/joa.12241
PMCID:
PMC4262344
AbstractArticlePDF–1.4M
19.
Zyxin modulates the transmigration of Haemophilus influenzae to the central nervous system
Yuko Miyazaki, Takashi Yusa, Saburo Matsuo, Yasuo Terauchi, Shuichi Miyazaki
Virulence. 2014 Aug 15; 5(6): 665–672. Published online 2014 Jul 15. doi: 10.4161/viru.29786
PMCID:
PMC4139407
AbstractArticlePDF–1.1M
20.
Small GTPase RhoE/Rnd3 is a critical regulator of Notch1 signaling
Zehua Zhu, Kristina Todorova, Kevin K. Lee, Jun Wang, Eunjeong Kwon, Ivan Kehayov, Hyung-Gu Kim, Vihren Kolev, G. Paolo Dotto, Sam W. Lee, Anna Mandinova
Cancer Res. Author manuscript; available in PMC 2015 Apr 1.
Published in final edited form as: Cancer Res. 2014 Apr 1; 74(7): 2082–2093. Published online 2014 Feb 13. doi: 10.1158/0008-5472.CAN-12-0452
PMCID:
PMC4031027
AbstractArticlePDF–1.6M

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