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Select item 112614501.

Vhl safeguards thymic epithelial cell identity and thymopoietic capacity by constraining Hif1a activity during development

Christiane Grammer, Julia A. Komorowska, Jeremy B. Swann

iScience. 2024 Jul 19; 27(7): 110258. Published online 2024 Jun 13. doi: 10.1016/j.isci.2024.110258

PMCID:: PMC11261450

Abstract Article PDF–11M

Select item 109876622.

Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin

Uttkarsh Ayyangar, Aneesh Karkhanis, Heather Tay, Aliya Farissa Binte Afandi, Oindrila Bhattacharjee, Lalitha KS, Sze Han Lee, James Chan, Srikala Raghavan

EMBO J. 2024 Apr; 43(7): 1113–1134. Published online 2024 Feb 28. doi: 10.1038/s44318-024-00039-y

PMCID:: PMC10987662

Abstract Article PDF–12M

Select item 108350413.

Single-cell RNA sequencing unveils unique transcriptomic signatures of endothelial cells and role of ENO1 in response to disturbed flow

Li-Jing Chen, Julie Yi-Shuan Li, Phu Nguyen, Ming He, Zhen Bouman Chen, Shankar Subramaniam, John Y.-J. Shyy, Shu Chien

Proc Natl Acad Sci U S A. 2024 Jan 30; 121(5): e2318904121. Published online 2024 Jan 23. doi: 10.1073/pnas.2318904121

PMCID:: PMC10835041

Abstract Article PDF–3.5M

Select item 105682544.

Unrevealed roles of extracellular enolase‑1 (ENO1) in promoting glycolysis and pro‑cancer activities in multiple myeloma via hypoxia‑inducible factor 1α

I-Che Chung, Wei-Ching Huang, Yung-Tsang Huang, Mao-Lin Chen, An-Wei Tsai, Pei-Yu Wu, Ta-Tung Yuan

Oncol Rep. 2023 Nov; 50(5): 205. Published online 2023 Oct 3. doi: 10.3892/or.2023.8642

PMCID:: PMC10568254

Abstract Article PDF–3.8M

Select item 103309145.

Sall4 restricts glycolytic metabolism in limb buds through transcriptional regulation of glycolytic enzyme genes

Hiroko Kawakami, Katherine Q. Chen, Ruizhi Zhang, Matthew P. Pappas, Abigail Bailey, Julie A. Reisz, Dylan Corcoran, Ryuichi Nishinakamura, Angelo D’Alessandro, Yasuhiko Kawakami

Dev Biol. Author manuscript; available in PMC 2024 Sep 1.

Published in final edited form as: Dev Biol. 2023 Sep; 501: 28–38. Published online 2023 Jun 8. doi: 10.1016/j.ydbio.2023.06.004

PMCID:: PMC10330914

Abstract Article PDF–1.7M

Select item 96038606.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 95539517.

Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming

Danyang Chong, Yayun Gu, Tongyu Zhang, Yu Xu, Dandan Bu, Zhong Chen, Na Xu, Liangkui Li, Xiyu Zhu, Haiquan Wang, Yangqing Li, Feng Zheng, Dongjin Wang, Peng Li, Li Xu, Zhibin Hu, Chaojun Li

Cell Discov. 2022; 8: 106. Published online 2022 Oct 11. doi: 10.1038/s41421-022-00447-6

PMCID:: PMC9553951

Abstract Article PDF–3.8M

Select item 89880088.

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

Ann-Helen Rosendahl, Mia Monnius, Anu Laitala, Antti Railo, Ilkka Miinalainen, Ritva Heljasvaara, Joni M. Mäki, Johanna Myllyharju

J Biol Chem. 2022 Apr; 298(4): 101787. Published online 2022 Mar 2. doi: 10.1016/j.jbc.2022.101787

PMCID:: PMC8988008

Abstract Article PDF–6.1M

Select item 79831569.

IL-7-induced phosphorylation of the adaptor Crk-like and other targets

Francesca B. Aiello, Tad Guszczynski, Wenqing Li, Julie A. Hixon, Qiong Jiang, Deborah L. Hodge, Tania Massignan, Chiara Di Lisio, Anand Merchant, Antonio D. Procopio, Valentina Bonetto, Scott K. Durum

Cell Signal. Author manuscript; available in PMC 2021 Mar 22.

Published in final edited form as: Cell Signal. 2018 Jul; 47: 131–141. Published online 2018 Mar 24. doi: 10.1016/j.cellsig.2018.03.008

PMCID:: PMC7983156

Abstract Article PDF–1.7M

Select item 741599110.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 699392511.

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers

Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang

FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R

PMCID:: PMC6993925

Abstract Article

Select item 669277012.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 662917613.

Loss of Super-Enhancer-Regulated circRNA Nfix Induces Cardiac Regeneration After Myocardial Infarction in Adult Mice

Senlin Huang, Xinzhong Li, Hao Zheng, Xiaoyun Si, Bing Li, Guoquan Wei, Chuling Li, Yijin Chen, Yanmei Chen, Wangjun Liao, Yulin Liao, Jianping Bin

Circulation. 2019 Jun 18; 139(25): 2857–2876. Published online 2019 Apr 5. doi: 10.1161/CIRCULATIONAHA.118.038361

PMCID:: PMC6629176

Abstract Article PDF–5.1M

Select item 662242614.

Von Hippel-Lindau Acts as a Metabolic Switch Controlling Nephron Progenitor Differentiation

Kasey Cargill, Shelby L. Hemker, Andrew Clugston, Anjana Murali, Elina Mukherjee, Jiao Liu, Daniel Bushnell, Andrew J. Bodnar, Zubaida Saifudeen, Jacqueline Ho, Carlton M. Bates, Dennis Kostka, Eric S. Goetzman, Sunder Sims-Lucas

J Am Soc Nephrol. 2019 Jul; 30(7): 1192–1205. Published online 2019 May 29. doi: 10.1681/ASN.2018111170

PMCID:: PMC6622426

Abstract Article

Select item 652253515.

Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner

Luis Zurkirchen, Sandra Varum, Sonja Giger, Annika Klug, Jessica Häusel, Raphaël Bossart, Martina Zemke, Claudio Cantù, Zeynep Kalender Atak, Nicola Zamboni, Konrad Basler, Lukas Sommer

Nat Commun. 2019; 10: 2192. Published online 2019 May 16. doi: 10.1038/s41467-019-09823-5

PMCID:: PMC6522535

Abstract Article PDF–7.1M

Select item 634668516.

Plasticity in the Glucagon Interactome Reveals Novel Proteins That Regulate Glucagon Secretion in α-TC1-6 Cells

Farzad Asadi, Savita Dhanvantari

Front Endocrinol (Lausanne) 2018; 9: 792. Published online 2019 Jan 18. doi: 10.3389/fendo.2018.00792

PMCID:: PMC6346685

Abstract Article PDF–3.6M

Select item 634600117.

ENOblock inhibits the pathology of diet-induced obesity

Haaglim Cho, Ji-Hyung Lee, JungIn Um, Sunwook Kim, Yukyung Kim, Woong-Hee Kim, Yong Sook Kim, Haushabhau S. Pagire, Jin Hee Ahn, Youngkeun Ahn, Young-Tae Chang, Da-Woon Jung, Darren R. Williams

Sci Rep. 2019; 9: 493. Published online 2019 Jan 24. doi: 10.1038/s41598-018-36715-3

PMCID:: PMC6346001

Abstract Article PDF–3.9M

Select item 633346018.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 631390019.

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization

Darryl S. Watkins, Jason D. True, Amber L. Mosley, Anthony J. Baucum, II

Proteomes. 2018 Dec; 6(4): 53. Published online 2018 Dec 17. doi: 10.3390/proteomes6040053

Correction in:: Proteomes. 2019 Mar; 7(1): 7.

PMCID:: PMC6313900

Abstract Article PDF–2.5M

Select item 626277720.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214