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Select item 112161731.

Diverse Fgfr1 signaling pathways and endocytic trafficking regulate mesoderm development

James F. Clark, Philippe Soriano

Genes Dev. 2024 May 1; 38(9-10): 393–414. doi: 10.1101/gad.351593.124

PMCID:: PMC11216173

Abstract Article PDF–17M

Select item 110674672.

Core planar cell polarity genes VANGL1 and VANGL2 in predisposition to congenital vertebral malformations

Xin Feng, Yongyu Ye, Jianan Zhang, Yuanqiang Zhang, Sen Zhao, Judith C. W. Mak, Nao Otomo, Zhengye Zhao, Yuchen Niu, Yoshiro Yonezawa, Guozhuang Li, Mao Lin, Xiaoxin Li, Prudence Wing Hang Cheung, Kexin Xu, Kazuki Takeda, Shengru Wang, Junjie Xie, Toshiaki Kotani, Vanessa N. T. Choi, You-Qiang Song, Yang Yang, Keith Dip Kei Luk, Kin Shing Lee, Ziquan Li, Pik Shan Li, Connie Y. H. Leung, Xiaochen Lin, Xiaolu Wang, Guixing Qiu, DISCO (Deciphering disorders Involving Scoliosis and COmorbidities) study group, Kota Watanabe, Japanese Early Onset Scoliosis Research Group, Zhihong Wu, Jennifer E. Posey, Shiro Ikegawa, James R. Lupski, Jason Pui Yin Cheung, Terry Jianguo Zhang, Bo Gao, Nan Wu

Proc Natl Acad Sci U S A. 2024 Apr 30; 121(18): e2310283121. Published online 2024 Apr 26. doi: 10.1073/pnas.2310283121

PMCID:: PMC11067467

Abstract Article PDF–11M

Select item 99237803.

Lfng and Dll3 cooperate to modulate protein interactions in cis and coordinate oscillatory Notch pathway activation in the segmentation clock

Matthew S. Bochter, Dustin Servello, Shinako Kakuda, Rachel D’Amico, Meaghan F. Ebetino, Robert S. Haltiwanger, Susan E. Cole

Dev Biol. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: Dev Biol. 2022 Jul; 487: 42–56. Published online 2022 Apr 13. doi: 10.1016/j.ydbio.2022.04.004

PMCID:: PMC9923780

Abstract Article PDF–2.0M

Select item 95344134.

The RNA helicase DDX6 controls early mouse embryogenesis by repressing aberrant inhibition of BMP signaling through miRNA-mediated gene silencing

Jessica Kim, Masafumi Muraoka, Hajime Okada, Atsushi Toyoda, Rieko Ajima, Yumiko Saga

PLoS Genet. 2022 Oct; 18(10): e1009967. Published online 2022 Oct 5. doi: 10.1371/journal.pgen.1009967

PMCID:: PMC9534413

Abstract Article PDF–3.8M

Select item 93405475.

Imaging the onset of oscillatory signaling dynamics during mouse embryo gastrulation

Henning J. Falk, Takehito Tomita, Gregor Mönke, Katie McDole, Alexander Aulehla

Development. 2022 Jul 1; 149(13): dev200083. Published online 2022 Jul 11. doi: 10.1242/dev.200083

PMCID:: PMC9340547

Abstract Article

Select item 82462636.

Saturation mutagenesis defines novel mouse models of severe spine deformity

Jonathan J. Rios, Kristin Denton, Hao Yu, Kandamurugu Manickam, Shannon Garner, Jamie Russell, Sara Ludwig, Jill A. Rosenfeld, Pengfei Liu, Jake Munch, Daniel J. Sucato, Bruce Beutler, Carol A. Wise

Dis Model Mech. 2021 Jun 1; 14(6): dmm048901. Published online 2021 Jun 18. doi: 10.1242/dmm.048901

PMCID:: PMC8246263

Abstract Article

Select item 78863307.

Olig3 regulates early cerebellar development

Elijah D Lowenstein, Aleksandra Rusanova, Jonas Stelzer, Marc Hernaiz-Llorens, Adrian E Schroer, Ekaterina Epifanova, Francesca Bladt, Eser Göksu Isik, Sven Buchert, Shiqi Jia, Victor Tarabykin, Luis R Hernandez-Miranda

eLife. 2021; 10: e64684. Published online 2021 Feb 16. doi: 10.7554/eLife.64684

PMCID:: PMC7886330

Abstract Article PDF–8.1M

Select item 77179048.

Fgf4 maintains Hes7 levels critical for normal somite segmentation clock function

Matthew J Anderson, Valentin Magidson, Ryoichiro Kageyama, Mark Lewandoski

eLife. 2020; 9: e55608. Published online 2020 Nov 19. doi: 10.7554/eLife.55608

PMCID:: PMC7717904

Abstract Article PDF–6.9M

Select item 73919629.

A β-catenin gradient links the clock and wavefront systems in mouse embryo segmentation

Alexander Aulehla, Winfried Wiegraebe, Valerie Baubet, Matthias B. Wahl, Chuxia Deng, Makoto Taketo, Mark Lewandoski, Olivier Pourquié

Nat Cell Biol. Author manuscript; available in PMC 2020 Jul 30.

Published in final edited form as: Nat Cell Biol. 2008 Feb; 10(2): 186–193. Published online 2007 Dec 23. doi: 10.1038/ncb1679

PMCID:: PMC7391962

Abstract Article PDF–1.6M

Select item 728214710.

Genetic Interaction Between Lrp6 and Wnt5a During Mouse Development

Emma Andersson, Lenka Bryjova, Kristin Biris, Terry P. Yamaguchi, Ernest Arenas, Vítězslav Bryja

Dev Dyn. Author manuscript; available in PMC 2020 Jun 9.

Published in final edited form as: Dev Dyn. 2010 Jan; 239(1): 237–245. doi: 10.1002/dvdy.22101

PMCID:: PMC7282147

Abstract Article PDF–987K

Select item 670371211.

FGF signaling patterns cell fate at the interface between tendon and bone

Ryan R. Roberts, Lauren Bobzin, Camilla S. Teng, Deepanwita Pal, Creighton T. Tuzon, Ronen Schweitzer, Amy E. Merrill

Development. 2019 Aug 1; 146(15): dev170241. Published online 2019 Aug 2. doi: 10.1242/dev.170241

PMCID:: PMC6703712

Abstract Article

Select item 667935912.

Sall4 regulates neuromesodermal progenitors and their descendants during body elongation in mouse embryos

Naoyuki Tahara, Hiroko Kawakami, Katherine Q. Chen, Aaron Anderson, Malina Yamashita Peterson, Wuming Gong, Pruthvi Shah, Shinichi Hayashi, Ryuichi Nishinakamura, Yasushi Nakagawa, Daniel J. Garry, Yasuhiko Kawakami

Development. 2019 Jul 15; 146(14): dev177659. Published online 2019 Jul 15. doi: 10.1242/dev.177659

PMCID:: PMC6679359

Abstract Article

Select item 607846213.

Presomitic mesoderm-specific expression of the transcriptional repressor Hes7 is controlled by E-box, T-box, and Notch signaling pathways

Shinichi Hayashi, Yasukazu Nakahata, Kenji Kohno, Takaaki Matsui, Yasumasa Bessho

J Biol Chem. 2018 Aug 3; 293(31): 12167–12176. Published online 2018 Jun 12. doi: 10.1074/jbc.RA118.003728

PMCID:: PMC6078462

Abstract Article PDF–2.0M

Select item 586900614.

ES cell-derived presomitic mesoderm-like tissues for analysis of synchronized oscillations in the segmentation clock

Marina Matsumiya, Takehito Tomita, Kumiko Yoshioka-Kobayashi, Akihiro Isomura, Ryoichiro Kageyama

Development. 2018 Feb 15; 145(4): dev156836. doi: 10.1242/dev.156836

PMCID:: PMC5869006

Abstract Article

Select item 584717215.

Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation

Katharina F. Sonnen, Volker M. Lauschke, Julia Uraji, Henning J. Falk, Yvonne Petersen, Maja C. Funk, Mathias Beaupeux, Paul François, Christoph A. Merten, Alexander Aulehla

Cell. 2018 Feb 22; 172(5): 1079–1090.e12. doi: 10.1016/j.cell.2018.01.026