U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO Profiles

Items: 1 to 20 of 308

1.
A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex
Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll
EMBO Rep. 2024 Aug; 25(8): 3432–3455. Published online 2024 Jun 28. doi: 10.1038/s44319-024-00184-9
PMCID:
PMC11315929
AbstractArticlePDF–3.4M
2.
NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance
Hengxing Chen, Yun Li, Huafu Li, Xiancong Chen, Huafeng Fu, Deli Mao, Wei Chen, Linxiang Lan, Chunming Wang, Kaishun Hu, Jia Li, Chengming Zhu, Ian Evans, Eddie Cheung, Daning Lu, Yulong He, Axel Behrens, Dong Yin, Changhua Zhang
Nature. 2024; 631(8021): 663–669. Published online 2024 Jul 3. doi: 10.1038/s41586-024-07620-9
PMCID:
PMC11254748
AbstractArticlePDF–17M
3.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
4.
Comprehensive analysis of DNA repair gene polymorphisms and survival in patients with early stage non‐small‐cell lung cancer
Min Kim, Hyo‐Gyoung Kang, Shin Yup Lee, Hyung Cheol Lee, Eung Bae Lee, Yi Young Choi, Won Kee Lee, Sukki Cho, Guang Jin, Hyo‐Sung Jheon, Ji Woong Son, Myung‐Hoon Lee, Deuk Kju Jung, Seung Ick Cha, Chang Ho Kim, Young Mo Kang, Sin Kam, Tae Hoon Jung, Sanghoon Jheon, Jae Yong Park
Cancer Sci. 2010 Nov; 101(11): 2436–2442. Published online 2010 Jul 31. doi: 10.1111/j.1349-7006.2010.01699.x
PMCID:
PMC11159840
AbstractArticlePDF–209K
5.
Identification of increased NBS1 expression as a prognostic marker of squamous cell carcinoma of the oral cavity
Dennis Shin‐Shian Hsu, Shyue‐Yih Chang, Chung‐Ji Liu, Cheng‐Hwai Tzeng, Kou‐Juey Wu, Jung‐Yie Kao, Muh‐Hwa Yang
Cancer Sci. 2010 Apr; 101(4): 1029–1037. Published online 2009 Dec 15. doi: 10.1111/j.1349-7006.2009.01471.x
PMCID:
PMC11159783
AbstractArticlePDF–589K
6.
Increased risk of larynx cancer in heterozygous carriers of the I171V mutation of the NBS1 gene
Iwona Ziólkowska, Maria Mosor, Malgorzata Wierzbicka, Malgorzata Rydzanicz, Monika Pernak‐Schwarz, Jerzy Nowak
Cancer Sci. 2007 Nov; 98(11): 1701–1705. Published online 2007 Aug 23. doi: 10.1111/j.1349-7006.2007.00594.x
PMCID:
PMC11158328
AbstractArticlePDF–102K
7.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
8.
GSTpi reduces DNA damage and cell death by regulating the ubiquitination and nuclear translocation of NBS1
Jinyi Zhou, Lili Gu, Yingying Shi, Ting Huang, Xirui Fan, Xiaowen Bi, Shuai Lu, Juanjuan Liang, Lan Luo, Peng Cao, Zhimin Yin
Cell Mol Life Sci. 2022 Jan; 79(1): 54. Published online 2021 Dec 22. doi: 10.1007/s00018-021-04057-5
PMCID:
PMC11072236
AbstractArticlePDF–11M
9.
The NSP3 protein of SARS-CoV-2 binds fragile X mental retardation proteins to disrupt UBAP2L interactions
Dimitriya H Garvanska, R Elias Alvarado, Filip Oskar Mundt, Richard Lindqvist, Josephine Kerzel Duel, Fabian Coscia, Emma Nilsson, Kumari Lokugamage, Bryan A Johnson, Jessica A Plante, Dorothea R Morris, Michelle N Vu, Leah K Estes, Alyssa M McLeland, Jordyn Walker, Patricia A Crocquet-Valdes, Blanca Lopez Mendez, Kenneth S Plante, David H Walker, Melanie Bianca Weisser, Anna K Överby, Matthias Mann, Vineet D Menachery, Jakob Nilsson
EMBO Rep. 2024 Feb; 25(2): 902–926. Published online 2024 Jan 2. doi: 10.1038/s44319-023-00043-z
PMCID:
PMC10897489
AbstractArticlePDF–8.2M
10.
Suppression of NBS1 Upregulates CyclinB to Induce Olaparib Sensitivity in Ovarian Cancer
Ailing Zhong, Chien-shan Cheng, Ren quan Lu, Lin Guo
Technol Cancer Res Treat. 2024; 23: 15330338231212085. Published online 2024 Jan 8. doi: 10.1177/15330338231212085
PMCID:
PMC10777771
AbstractArticlePDF–11M
11.
Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification
Camila M. Aprosoff, Boris J.A. Dyakov, Vivian H.W. Cheung, Cassandra J. Wong, Mikaela Palandra, Anne-Claude Gingras, Haley D.M. Wyatt
J Proteome Res. 2023 Jun 2; 22(6): 1660–1681. Published online 2023 Apr 18. doi: 10.1021/acs.jproteome.2c00706
PMCID:
PMC10243116
AbstractArticlePDF–13M
12.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
13.
Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis
Jieqiong Zhang, Zhenhua Hu, Hwa Hwa Chung, Yun Tian, Kah Weng Lau, Zheng Ser, Yan Ting Lim, Radoslaw M. Sobota, Hwei Fen Leong, Benjamin Jieming Chen, Clarisse Jingyi Yeo, Shawn Ying Xuan Tan, Jian Kang, Dennis Eng Kiat Tan, Ieng Fong Sou, Urszula Lucja McClurg, Manikandan Lakshmanan, Thamil Selvan Vaiyapuri, Anandhkumar Raju, Esther Sook Miin Wong, Vinay Tergaonkar, Ravisankar Rajarethinam, Elina Pathak, Wai Leong Tam, Ern Yu Tan, Wee-Wei Tee
Nat Commun. 2023; 14: 2439. Published online 2023 Apr 28. doi: 10.1038/s41467-023-38132-1
PMCID:
PMC10147683
AbstractArticlePDF–7.7M
14.
Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage
Sanna Abbasi, Laila Bayat, Caroline Schild-Poulter
Int J Mol Sci. 2023 Apr; 24(8): 7041. Published online 2023 Apr 11. doi: 10.3390/ijms24087041
PMCID:
PMC10138931
AbstractArticlePDF–4.0M
15.
The NBN founder mutation—Evidence for a country specific difference in age at cancer manifestation
Krystyna H. Chrzanowska, Eva Seemanova, Raymonda Varon, Martin Digweed, Dorota Piekutowska‐Abramczuk, Karl Sperling, Pavel Seeman
Cancer Rep (Hoboken) 2023 Feb; 6(2): e1700. Published online 2022 Aug 10. doi: 10.1002/cnr2.1700
PMCID:
PMC9939984
AbstractArticlePDF–1.3M
16.
RNF126‐Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple‐Negative Breast Cancer to Radiotherapy
Wenjing Liu, Min Zheng, Rou Zhang, Qiuyun Jiang, Guangshi Du, Yingying Wu, Chuanyu Yang, Fubing Li, Wei Li, Luzhen Wang, Jiao Wu, Lei Shi, Wenhui Li, Kai Zhang, Zhongmei Zhou, Rong Liu, Yingzheng Gao, Xinwei Huang, Songqing Fan, Xu Zhi, Dewei Jiang, Ceshi Chen
Adv Sci (Weinh) 2023 Feb; 10(5): 2203884. Published online 2022 Dec 23. doi: 10.1002/advs.202203884
PMCID:
PMC9929257
AbstractArticlePDF–6.3M
17.
NBN Pathogenic Germline Variants are Associated with Pan-Cancer Susceptibility and In Vitro DNA Damage Response Defects
Sami Belhadj, Aliya Khurram, Chaitanya Bandlamudi, Guillermo Palou-Márquez, Vignesh Ravichandran, Zoe Steinsnyder, Temima Wildman, Amanda Catchings, Yelena Kemel, Semanti Mukherjee, Benjamin Fesko, Kanika Arora, Miika Mehine, Sita Dandiker, Aalin Izhar, John Petrini, Susan Domchek, Katherine L. Nathanson, Jamie Brower, Fergus Couch, Zsofia Stadler, Mark Robson, Michael Walsh, Joseph Vijai, Michael Berger, Fran Supek, Rachid Karam, Sabine Topka, Kenneth Offit
Clin Cancer Res. 2023 Jan 17; 29(2): 422–431. Published online 2022 Nov 8. doi: 10.1158/1078-0432.CCR-22-1703
PMCID:
PMC9843434
AbstractArticlePDF–3.3M
18.
A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
PMCID:
PMC9769698
AbstractArticlePDF–2.7M
19.
Deubiquitinase USP2 stabilizes the MRE11–RAD50–NBS1 complex at DNA double-strand break sites by counteracting the ubiquitination of NBS1
Hyunsup Kim, Dongmin Kim, Hyemin Choi, Gwangsu Shin, Joon-Kyu Lee
J Biol Chem. 2023 Jan; 299(1): 102752. Published online 2022 Nov 25. doi: 10.1016/j.jbc.2022.102752
PMCID:
PMC9758435
AbstractArticlePDF–2.6M
20.
The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers
Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy
eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676
PMCID:
PMC9708086
AbstractArticlePDF–8.5M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

You are here: NCBI > Literature > PubMed Central (PMC)
Support Center