PMC Links for GEO Profiles (Select 29923022) - PMC

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 69882914.

Key genes with prognostic values in suppression of osteosarcoma metastasis using comprehensive analysis

Mi Li, Xin Jin, Hao Li, Gang Wu, Shanshan Wang, Caihong Yang, Sisi Deng

BMC Cancer. 2020; 20: 65. Published online 2020 Jan 28. doi: 10.1186/s12885-020-6542-z

PMCID:: PMC6988291

Abstract Article PDF–4.3M

Select item 63690115.

A 5-Lipoxygenase-Specific Sequence Motif Impedes Enzyme Activity and Confers Dependence on a Partner Protein

Erin E. Schexnaydre, Jana Gerstmeier, Ulrike Garscha, Paul M. Jordan, Oliver Werz, Marcia E. Newcomer

Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2020 Apr 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Apr; 1864(4): 543–551. Published online 2018 Oct 3. doi: 10.1016/j.bbalip.2018.09.011

PMCID:: PMC6369011

Abstract Article PDF–1.3M

Select item 63465896.

Genetic variation in the leukotriene pathway is associated with myocardial infarction in the Chinese population

Yilan Li, Xueming Xu, Dandan Zhang, Wei Cheng, Yanan Zhang, Bo Yu, Yao Zhang

Lipids Health Dis. 2019; 18: 25. Published online 2019 Jan 24. doi: 10.1186/s12944-019-0968-9

PMCID:: PMC6346589

Abstract Article PDF–730K

Select item 62035607.

Association between the polymorphism (rs17222919, −1316T/G) of 5-lipoxygenase-activating protein gene (ALOX5AP) and the risk of stroke: A meta analysis

Hui Ye, Xin Zhang, Zupeng Chen, Xu Li, Tiehui Zhang, Chao Yang, Lifa Huang

Medicine (Baltimore) 2018 Oct; 97(41): e12682. Published online 2018 Oct 12. doi: 10.1097/MD.0000000000012682

PMCID:: PMC6203560

Abstract Article PDF–682K

Select item 55316118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 49458719.

Genetic Variants in the Transcriptional Regulatory Region of the ALOX5AP gene and Susceptibility to Ischemic Stroke in Chinese Populations

Dongzhi Yang, Xiangnan Huang, Chuanju Cui, Yuchao Zhang, Ya Li, Xin Zang, Ying He, Hong Zheng

Sci Rep. 2016; 6: 29513. Published online 2016 Jul 15. doi: 10.1038/srep29513

PMCID:: PMC4945871

Abstract Article PDF–418K

Select item 493345810.

A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors

Jonathan M. Blevitt, Michael D. Hack, Krystal Herman, Leon Chang, John M. Keith, Tara Mirzadegan, Navin L. Rao, Alec D. Lebsack, Marcos E. Milla

J Biol Chem. 2016 Jun 10; 291(24): 12724–12731. Published online 2016 Apr 16. doi: 10.1074/jbc.M116.725325

PMCID:: PMC4933458

Abstract Article PDF–2.5M

Select item 483637011.

5-Lipoxygenase-activating protein rescues activity of 5-lipoxygenase mutations that delay nuclear membrane association and disrupt product formation

Jana Gerstmeier, Marcia E. Newcomer, Sophie Dennhardt, Erik Romp, Jana Fischer, Oliver Werz, Ulrike Garscha

FASEB J. 2016 May; 30(5): 1892–1900. Published online 2016 Feb 3. doi: 10.1096/fj.201500210R

PMCID:: PMC4836370

Abstract Article

Select item 437639012.

A Promoter Polymorphism (rs17222919, −1316T/G) of ALOX5AP Gene Is Associated with Decreased Risk of Ischemic Stroke in Two Independent Chinese Populations

Yujia Fan, Hui Chen, Aifan Li, Yunshu Shi, Yuchao Zhang, Qingchuan Feng, Yan Sun, Hong Zheng, Ying He

PLoS One. 2015; 10(3): e0122393. Published online 2015 Mar 27. doi: 10.1371/journal.pone.0122393

PMCID:: PMC4376390

Abstract Article PDF–324K

Select item 416133013.

Interrelationships between ALOX5AP Polymorphisms, Serum Leukotriene B4 Level and Risk of Acute Coronary Syndrome

Guoping He, Shan Ye, Jingjiao Hui, Dandan Shen, Chuanping Qi, Lianhong Xu, Yichao Qian

PLoS One. 2014; 9(9): e106596. Published online 2014 Sep 11. doi: 10.1371/journal.pone.0106596

PMCID:: PMC4161330

Abstract Article PDF–1.3M

Select item 412815414.

Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis

Devaraj Basavarajappa, Min Wan, Ana Lukic, Dieter Steinhilber, Bengt Samuelsson, Olof Rådmark

Proc Natl Acad Sci U S A. 2014 Aug 5; 111(31): 11371–11376. Published online 2014 Jul 17. doi: 10.1073/pnas.1410983111

PMCID:: PMC4128154

Abstract Article PDF–1.1M

Select item 409932515.

5-Lipoxygenase Activating Protein (FLAP) Dependent Leukotriene Biosynthesis Inhibition (MK591) Attenuates Lipid A Endotoxin-Induced Inflammation

Wen-Feng Fang, Ivor S. Douglas, Chin-Chou Wang, Hsu-Ching Kao, Ya-Ting Chang, Chia-Cheng Tseng, Kuo-Tung Huang, Huang-Chih Chang, Meng-Chih Lin

PLoS One. 2014; 9(7): e102622. Published online 2014 Jul 15. doi: 10.1371/journal.pone.0102622

PMCID:: PMC4099325

Abstract Article PDF–3.5M

Select item 405520516.

The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)

C Pergola, J Gerstmeier, B Mönch, B Çalışkan, S Luderer, C Weinigel, D Barz, J Maczewsky, S Pace, A Rossi, L Sautebin, E Banoglu, O Werz

Br J Pharmacol. 2014 Jun; 171(12): 3051–3064. Published online 2014 May 27. doi: 10.1111/bph.12625

PMCID:: PMC4055205

Abstract Article PDF–1.5M

Select item 402369217.

Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease

Themistocles L. Assimes, Joshua W. Knowles, Jame s R. Priest, Analabha Basu, Kelly A. Volcik, Audrey Southwick, Holly K. Tabor, Jaana Hartiala, Hooman Allayee, Megan L. Grove, Raymond Tabibiazar, Stephen Sidney, Stephen P. Fortmann, Alan Go, Mark Hlatky, Carlos Iribarren, Eric Boerwinkle, Richard Myers, Neil Risch, Thomas Quertermous

Hum Genet. Author manuscript; available in PMC 2014 May 16.

Published in final edited form as: Hum Genet. 2008 May; 123(4): 399–408. Published online 2008 Mar 28. doi: 10.1007/s00439-008-0489-5

PMCID:: PMC4023692

Abstract Article PDF–316K

Select item 397876418.

A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients

Suyoun Chung, Siew-Kee Low, Hitoshi Zembutsu, Atsushi Takahashi, Michiaki Kubo, Mitsunori Sasa, Yusuke Nakamura

Breast Cancer Res. 2013; 15(5): R81. Published online 2013 Sep 11. doi: 10.1186/bcr3475

PMCID:: PMC3978764

Abstract Article PDF–282K

Select item 390837019.

A genome-wide association study for reading and language abilities in two population cohorts

M Luciano, D M Evans, N K Hansell, S E Medland, G W Montgomery, N G Martin, M J Wright, T C Bates

Genes Brain Behav. 2013 Aug; 12(6): 645–652. Published online 2013 Jun 20. doi: 10.1111/gbb.12053

PMCID:: PMC3908370

Abstract Article PDF–513K

Select item 373345820.

ALOX5AP Variants are Associated with In-Stent Restenosis After Percutaneous Coronary Intervention

Svati H. Shah, Elizabeth R. Hauser, David Crosslin, Liyong Wang, Carol Haynes, Jessica Connelly, Sarah Nelson, Jessica Johnson, Shera Gadson, Charlotte L. Nelson, David Seo, Simon Gregory, William E. Kraus, Christopher B. Granger, Pascal Goldschmidt-Clermont, L. Kristin Newby

Atherosclerosis. Author manuscript; available in PMC 2013 Aug 5.

Published in final edited form as: Atherosclerosis. 2008 Nov; 201(1): 148–154. Published online 2008 Feb 12. doi: 10.1016/j.atherosclerosis.2008.01.011

PMCID:: PMC3733458

Abstract Article PDF–452K

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