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Items: 1 to 20 of 40

1.
Ciliogenesis-associated Kinase 1 Promotes Breast Cancer Cell Proliferation and Chemoresistance via Phosphorylating ERK1
Yanling He, Xinyuan Zhang, Weijun Pan, Jiebiao Zhang, Weiliang Zhu, Jian Zhang, Jian Shi
Int J Biol Sci. 2024; 20(7): 2403–2421. Published online 2024 Apr 8. doi: 10.7150/ijbs.87442
PMCID:
PMC11077371
AbstractArticlePDF–10M
2.
The Scaffold Protein KATNIP Enhances CILK1 Control of Primary Cilia
Jacob S. Turner, Ellie A. McCabe, Kevin W. Kuang, Casey D. Gailey, David L. Brautigan, Ana Limerick, Elena X. Wang, Zheng Fu
Mol Cell Biol. 2023; 43(9): 472–480. Published online 2023 Sep 4. doi: 10.1080/10985549.2023.2246870
PMCID:
PMC10512882
AbstractArticlePDF–1.3M
3.
BROMI/TBC1D32 together with CCRK/CDK20 and FAM149B1/JBTS36 contributes to intraflagellar transport turnaround involving ICK/CILK1
Yuuki Satoda, Tatsuro Noguchi, Taiju Fujii, Aoi Taniguchi, Yohei Katoh, Kazuhisa Nakayama
Mol Biol Cell. 2022 Aug 1; 33(9): ar79. Published online 2022 Jul 21. doi: 10.1091/mbc.E22-03-0089
PMCID:
PMC9582636
AbstractArticlePDF–6.5M
4.
Isc10, an inhibitor of the Smk1 MAPK, prevents activation loop autophosphorylation and substrate phosphorylation through separate mechanisms
Abhimannyu Rimal, Thomas M. Swayne, Zeal P. Kamdar, Madison A. Tewey, Edward Winter
J Biol Chem. 2022 Oct; 298(10): 102450. Published online 2022 Sep 3. doi: 10.1016/j.jbc.2022.102450
PMCID:
PMC9558048
AbstractArticlePDF–1.2M
5.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
Anterograde trafficking of ciliary MAP kinase–like ICK/CILK1 by the intraflagellar transport machinery is required for intraciliary retrograde protein trafficking
Kentaro Nakamura, Tatsuro Noguchi, Mariko Takahara, Yoshihiro Omori, Takahisa Furukawa, Yohei Katoh, Kazuhisa Nakayama
J Biol Chem. 2020 Sep 18; 295(38): 13363–13376. Published online 2020 Jul 29. doi: 10.1074/jbc.RA120.014142
PMCID:
PMC7504932
AbstractArticlePDF–4.9M
8.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
9.
Functional Alterations in Ciliogenesis-Associated Kinase 1 (CILK1) that Result from Mutations Linked to Juvenile Myoclonic Epilepsy
Eric J. Wang, Casey D. Gailey, David L. Brautigan, Zheng Fu
Cells. 2020 Mar; 9(3): 694. Published online 2020 Mar 12. doi: 10.3390/cells9030694
PMCID:
PMC7140639
AbstractArticlePDF–1.7M
10.
Ciliogenesis associated kinase 1 (CILK1): targets and functions in various organ systems
Zheng Fu, Casey D. Gailey, Eric J. Wang, David L. Brautigan
FEBS Lett. Author manuscript; available in PMC 2020 Nov 1.
Published in final edited form as: FEBS Lett. 2019 Nov; 593(21): 2990–3002. Published online 2019 Sep 20. doi: 10.1002/1873-3468.13600
PMCID:
PMC6848764
AbstractArticlePDF–850K
11.
Ciliopathy-Associated Protein Kinase ICK Requires Its Non-Catalytic Carboxyl-Terminal Domain for Regulation of Ciliogenesis
Yoon Seon Oh, Eric J. Wang, Casey D. Gailey, David L. Brautigan, Benjamin L. Allen, Zheng Fu
Cells. 2019 Jul; 8(7): 677. Published online 2019 Jul 4. doi: 10.3390/cells8070677
PMCID:
PMC6678984
AbstractArticlePDF–1.5M
12.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
13.
The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation
Tyler B Faust, Yang Li, Curtis W Bacon, Gwendolyn M Jang, Amit Weiss, Bhargavi Jayaraman, Billy W Newton, Nevan J Krogan, Iván D'Orso, Alan D Frankel
eLife. 2018; 7: e31879. Published online 2018 May 30. doi: 10.7554/eLife.31879
PMCID:
PMC5999396
AbstractArticlePDF–3.6M
14.
The human cytoplasmic dynein interactome reveals novel activators of motility
William B Redwine, Morgan E DeSantis, Ian Hollyer, Zaw Min Htet, Phuoc Tien Tran, Selene K Swanson, Laurence Florens, Michael P Washburn, Samara L Reck-Peterson
eLife. 2017; 6: e28257. Published online 2017 Jul 18. doi: 10.7554/eLife.28257
PMCID:
PMC5533585
AbstractArticlePDF–5.9M
15.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
16.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
17.
An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome
S. Paige Taylor, Michaela Kunova Bosakova, Miroslav Varecha, Lukas Balek, Tomas Barta, Lukas Trantirek, Iva Jelinkova, Ivan Duran, Iva Vesela, Kimberly N. Forlenza, Jorge H. Martin, Ales Hampl, University of Washington Center for Mendelian Genomics, Michael Bamshad, Deborah Nickerson, Margie L. Jaworski, Jieun Song, Hyuk Wan Ko, Daniel H. Cohn, Deborah Krakow, Pavel Krejci
Hum Mol Genet. 2016 Sep 15; 25(18): 3998–4011. Published online 2016 Jul 27. doi: 10.1093/hmg/ddw240
PMCID:
PMC5291234
AbstractArticlePDF–2.1M
18.
Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease
Felipe Roberti Teixeira, Suzanne J. Randle, Shachi P. Patel, Tycho E.T. Mevissen, Grasilda Zenkeviciute, Tie Koide, David Komander, Heike Laman
Biochem J. 2016 Oct 15; 473(20): 3563–3580. Prepublished online 2016 Aug 8. Published online 2016 Oct 11. doi: 10.1042/BCJ20160387
PMCID:
PMC5260939
AbstractArticlePDF–1.1M
19.
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms
Karsten Boldt, Jeroen van Reeuwijk, Qianhao Lu, Konstantinos Koutroumpas, Thanh-Minh T. Nguyen, Yves Texier, Sylvia E. C. van Beersum, Nicola Horn, Jason R. Willer, Dorus A. Mans, Gerard Dougherty, Ideke J. C. Lamers, Karlien L. M. Coene, Heleen H. Arts, Matthew J. Betts, Tina Beyer, Emine Bolat, Christian Johannes Gloeckner, Khatera Haidari, Lisette Hetterschijt, Daniela Iaconis, Dagan Jenkins, Franziska Klose, Barbara Knapp, Brooke Latour, Stef J. F. Letteboer, Carlo L. Marcelis, Dragana Mitic, Manuela Morleo, Machteld M. Oud, Moniek Riemersma, Susan Rix, Paulien A. Terhal, Grischa Toedt, Teunis J. P. van Dam, Erik de Vrieze, Yasmin Wissinger, Ka Man Wu, Gordana Apic, Philip L. Beales, Oliver E. Blacque, Toby J. Gibson, Martijn A. Huynen, Nicholas Katsanis, Hannie Kremer, Heymut Omran, Erwin van Wijk, Uwe Wolfrum, François Kepes, Erica E. Davis, Brunella Franco, Rachel H. Giles, Marius Ueffing, Robert B. Russell, Ronald Roepman, UK10K Rare Diseases Group
Nat Commun. 2016; 7: 11491. Published online 2016 May 13. doi: 10.1038/ncomms11491
PMCID:
PMC4869170
AbstractArticlePDF–2.0M
20.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M

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