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Select item 115196071.

The link between amyloid β and ferroptosis pathway in Alzheimer’s disease progression

Naďa Majerníková, Alejandro Marmolejo-Garza, Casandra Salinas Salinas, Minh D. A. Luu, Yuequ Zhang, Marina Trombetta-Lima, Tamara Tomin, Ruth Birner-Gruenberger, Šárka Lehtonen, Jari Koistinaho, Justina C. Wolters, Scott Ayton, Wilfred F. A. den Dunnen, Amalia M. Dolga

Cell Death Dis. 2024 Oct; 15(10): 782. Published online 2024 Oct 28. doi: 10.1038/s41419-024-07152-0

PMCID:: PMC11519607

Abstract Article PDF–8.2M

Select item 115075122.

Pathology of Amyloid-β (Aβ) Peptide Peripheral Clearance in Alzheimer’s Disease

Andrey Tsoy, Bauyrzhan Umbayev, Aliya Kassenova, Bibifatima Kaupbayeva, Sholpan Askarova

Int J Mol Sci. 2024 Oct; 25(20): 10964. Published online 2024 Oct 11. doi: 10.3390/ijms252010964

PMCID:: PMC11507512

Abstract Article PDF–1.1M

Select item 114970343.

Secondary Nucleation of Aβ Revealed by Single‐Molecule and Computational Approaches

Nathan Meyer, Nicolas Arroyo, Lois Roustan, Jean‐Marc Janot, Saly Charles‐Achille, Joan Torrent, Fabien Picaud, Sébastien Balme

Adv Sci (Weinh) 2024 Oct; 11(39): 2404916. Published online 2024 Aug 19. doi: 10.1002/advs.202404916

PMCID:: PMC11497034

Abstract Article PDF–3.6M

Select item 114854004.

Cellular prion protein acts as mediator of amyloid beta uptake by caveolin‐1 causing cellular dysfunctions in vitro and in vivo

Angela da Silva Correia, Matthias Schmitz, Anna‐Lisa Fischer, Susana da Silva Correia, Franco L. Simonetti, Gesine Saher, Roberto Goya‐Maldonado, Amandeep Singh Arora, Andre Fischer, Tiago F. Outeiro, Inga Zerr

Alzheimers Dement. 2024 Oct; 20(10): 6776–6792. Published online 2024 Aug 30. doi: 10.1002/alz.14120

PMCID:: PMC11485400

Abstract Article PDF–5.9M

Select item 114609935.

Amyloid beta peptides (Aβ) from Alzheimer’s disease neuronal secretome induce endothelial activation in a human cerebral microvessel model

Yu Jung Shin, Kira M. Evitts, Solhee Jin, Caitlin Howard, Margaret Sharp-Milgrom, Tiara Schwarze-Taufiq, Chizuru Kinoshita, Jessica E. Young, Ying Zheng

Neurobiol Dis. Author manuscript; available in PMC 2024 Oct 8.

Published in final edited form as: Neurobiol Dis. 2023 Jun 1; 181: 106125. Published online 2023 Apr 14. doi: 10.1016/j.nbd.2023.106125

PMCID:: PMC11460993

Abstract Article PDF–2.1M

Select item 114569976.

Unveiling the effect of CaCl₂ on amyloid β aggregation via supercritical angle Raman and fluorescence spectroscopy and microscopy

Nathalia Simea Münch, Subir Das, Stefan Seeger

Phys Chem Chem Phys. 2024 Oct 23; 26(41): 26266–26276. Published online 2024 Oct 1. doi: 10.1039/d4cp00996g

PMCID:: PMC11456997

Abstract Article

Select item 113874777.

Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology

Annie M. Goettemoeller, Emmie Banks, Prateek Kumar, Viktor J. Olah, Katharine E. McCann, Kelly South, Christina C. Ramelow, Anna Eaton, Duc M. Duong, Nicholas T. Seyfried, David Weinshenker, Srikant Rangaraju, Matthew J. M. Rowan

Nat Commun. 2024; 15: 7918. Published online 2024 Sep 10. doi: 10.1038/s41467-024-52297-3

PMCID:: PMC11387477

Abstract Article PDF–4.4M

Select item 113527358.

Are Women with Polycystic Ovary Syndrome at Increased Risk of Alzheimer Disease? Lessons from Insulin Resistance, Tryptophan and Gonadotropin Disturbances and Their Link with Amyloid-Beta Aggregation

Joachim Sobczuk, Katarzyna Paczkowska, Szymon Andrusiów, Marek Bolanowski, Jacek Daroszewski

Biomolecules. 2024 Aug; 14(8): 918. Published online 2024 Jul 28. doi: 10.3390/biom14080918

PMCID:: PMC11352735

Abstract Article PDF–1.0M

Select item 112969149.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 1129344210.

CNTN4 modulates neural elongation through interplay with APP

Rosemary A. Bamford, Amila Zuko, Madeline Eve, Jan J. Sprengers, Harm Post, Renske L. R. E. Taggenbrock, Dominique Fäβler, Annika Mehr, Owen J. R. Jones, Aurimas Kudzinskas, Josan Gandawijaya, Ulrike C. Müller, Martien J. H. Kas, J. Peter H. Burbach, Asami Oguro-Ando

Open Biol. 2024 May; 14(5): 240018. Published online May 15, 2024. doi: 10.1098/rsob.240018

PMCID:: PMC11293442

Abstract Article PDF–6.0M

Select item 1126920211.

CryoET of β-amyloid and tau within postmortem Alzheimer’s disease brain

Madeleine A. G. Gilbert, Nayab Fatima, Joshua Jenkins, Thomas J. O’Sullivan, Andreas Schertel, Yehuda Halfon, Martin Wilkinson, Tjado H. J. Morrema, Mirjam Geibel, Randy J. Read, Neil A. Ranson, Sheena E. Radford, Jeroen J. M. Hoozemans, René A. W. Frank

Nature. 2024; 631(8022): 913–919. Published online 2024 Jul 10. doi: 10.1038/s41586-024-07680-x

PMCID:: PMC11269202

Abstract Article PDF–24M

Select item 1126566912.

Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer’s disease

Rikesh M. Rajani, Robert Ellingford, Mariam Hellmuth, Samuel S. Harris, Orjona S. Taso, David Graykowski, Francesca Kar Wey Lam, Charles Arber, Emre Fertan, John S. H. Danial, Matthew Swire, Marcus Lloyd, Tatiana A. Giovannucci, Mathieu Bourdenx, David Klenerman, Robert Vassar, Selina Wray, Carlo Sala Frigerio, Marc Aurel Busche

PLoS Biol. 2024 Jul; 22(7): e3002727. Published online 2024 Jul 23. doi: 10.1371/journal.pbio.3002727

PMCID:: PMC11265669

Abstract Article PDF–2.7M

Select item 1125868813.

Modulation of Alzheimer’s Disease Aβ40 Fibril Polymorphism by the Small Heat Shock Protein αB-Crystallin

Natalia Rodina, Simon Hornung, Riddhiman Sarkar, Saba Suladze, Carsten Peters, Philipp W. N. Schmid, Zheng Niu, Martin Haslbeck, Johannes Buchner, Aphrodite Kapurniotu, Bernd Reif

J Am Chem Soc. 2024 Jul 17; 146(28): 19077–19087. Published online 2024 Jul 8. doi: 10.1021/jacs.4c03504

PMCID:: PMC11258688

Abstract Article PDF–4.4M

Select item 1124769814.

Sex‐specific associations between AD genotype and the microbiome of human amyloid beta knock‐in (hAβ‐KI) mice

Sage J. B. Dunham, Julio Avelar‐Barragan, Jason A. Rothman, Eric D. Adams, Gina Faraci, Stefania Forner, Shimako Kawauchi, Andrea J. Tenner, Kim N. Green, Frank M. LaFerla, Grant R. MacGregor, Mark Mapstone, Katrine L. Whiteson

Alzheimers Dement. 2024 Jul; 20(7): 4935–4950. Published online 2024 Apr 4. doi: 10.1002/alz.13794

PMCID:: PMC11247698

Abstract Article PDF–5.9M

Select item 1124767815.

The presenilin 1 mutation P436S causes familial Alzheimer's disease with elevated Aβ43 and atypical clinical manifestations

Charles Arber, Christopher R. S. Belder, Filip Tomczuk, Rebecca Gabriele, Yazead Buhidma, Clíona Farrell, Antoinette O'Connor, Helen Rice, Tammaryn Lashley, Nick C. Fox, Natalie S. Ryan, Selina Wray

Alzheimers Dement. 2024 Jul; 20(7): 4717–4726. Published online 2024 Jun 2. doi: 10.1002/alz.13904

PMCID:: PMC11247678

Abstract Article PDF–2.1M

Select item 1121489016.

Distinctive contribution of two additional residues in protein aggregation of Aβ42 and Aβ40 isoforms

Dongjoon Im, Tae Su Choi

BMB Rep. 2024 Jun 30; 57(6): 263–272. Published online 2024 May 2. doi: 10.5483/BMBRep.2024-0044

PMCID:: PMC11214890

Abstract Article PDF–3.0M

Select item 1116762217.

Semantic intrusion errors as a function of age, amyloid, and volumetric loss: a confirmatory path analysis

D. Diane Zheng, Rosie E. Curiel Cid, Ranjan Duara, Marcela Kitaigorodsky, Elizabeth Crocco, David A. Loewenstein

Int Psychogeriatr. Author manuscript; available in PMC 2024 Jun 12.

Published in final edited form as: Int Psychogeriatr. 2022 Nov; 34(11): 991–1001. Published online 2021 Jan 18. doi: 10.1017/S1041610220004007

PMCID:: PMC11167622

Abstract Article PDF–513K

Select item 1111592618.

Ectodomain shedding of the receptor for advanced glycation end products: a novel therapeutic target for Alzheimer’s disease

Ling Zhang, Rolf Postina, Yingqun Wang

Cell Mol Life Sci. 2009 Dec; 66(24): 3923–3935. Published online 2009 Aug 12. doi: 10.1007/s00018-009-0121-4

PMCID:: PMC11115926

Abstract Article PDF–398K

Select item 1111374419.

Amyloid beta receptors responsible for neurotoxicity and cellular defects in Alzheimer’s disease

Tae-In Kam, Youngdae Gwon, Yong-Keun Jung

Cell Mol Life Sci. 2014 Dec; 71(24): 4803–4813. Published online 2014 Aug 24. doi: 10.1007/s00018-014-1706-0

PMCID:: PMC11113744

Abstract Article PDF–854K

Select item 1110530220.

Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA

Simone Eggert, A. C. Gonzalez, C. Thomas, S. Schilling, S. M. Schwarz, C. Tischer, V. Adam, P. Strecker, V. Schmidt, T. E. Willnow, G. Hermey, C. U. Pietrzik, E. H. Koo, Stefan Kins

Cell Mol Life Sci. 2018 Jan; 75(2): 301–322. Published online 2017 Aug 10. doi: 10.1007/s00018-017-2625-7