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Select item 114908861.

TBK1 adaptor AZI2/NAP1 regulates NDP52-driven mitochondrial autophagy

Ryu Endo, Hiroki Kinefuchi, Momoha Sawada, Reika Kikuchi, Waka Kojima, Noriyuki Matsuda, Koji Yamano

J Biol Chem. 2024 Oct; 300(10): 107775. Published online 2024 Sep 12. doi: 10.1016/j.jbc.2024.107775

PMCID:: PMC11490886

Abstract Article PDF–4.8M

Select item 114010342.

Proximity labeling reveals dynamic changes in the SQSTM1 protein network

Alejandro N. Rondón-Ortiz, Lushuang Zhang, Peter E.A. Ash, Avik Basu, Sambhavi Puri, Sophie J.F. van der Spek, Zihan Wang, Luke Dorrian, Andrew Emili, Benjamin Wolozin

J Biol Chem. 2024 Sep; 300(9): 107621. Published online 2024 Aug 3. doi: 10.1016/j.jbc.2024.107621

PMCID:: PMC11401034

Abstract Article PDF–5.4M

Select item 112969143.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 109366364.

AZI2 mediates TBK1 activation at unresolved selective autophagy cargo receptor complexes with implications for CD8 T-cell infiltration in breast cancer

Syn Kok Yeo, Michael Haas, Kanakaraju Manupati, Mingang Hao, Fuchun Yang, Song Chen, Jun-Lin Guan

Autophagy. 2024; 20(3): 525–540. Published online 2023 Sep 21. doi: 10.1080/15548627.2023.2259775

PMCID:: PMC10936636

Abstract Article PDF–8.4M

Select item 107023665.

NAK-associated protein 1/NAP1 activates TBK1 to ensure accurate mitosis and cytokinesis

Swagatika Paul, Shireen A. Sarraf, Ki Hong Nam, Leila Zavar, Nicole DeFoor, Sahitya Ranjan Biswas, Lauren E. Fritsch, Tomer M. Yaron, Jared L. Johnson, Emily M. Huntsman, Lewis C. Cantley, Alban Ordureau, Alicia M. Pickrell

J Cell Biol. 2024 Feb 5; 223(2): e202303082. Published online 2023 Dec 7. doi: 10.1083/jcb.202303082

PMCID:: PMC10702366

Abstract Article PDF–8.5M

Select item 103338846.

Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions

Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2023 Jul; 19(7): e11164. Published online 2023 May 23. doi: 10.15252/msb.202211164

PMCID:: PMC10333884

Abstract Article PDF–5.0M

Select item 100729067.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 99711958.

CEMIP, acting as a scaffold protein for bridging GRAF1 and MIB1, promotes colorectal cancer metastasis via activating CDC42/MAPK pathway

Guojie Xu, Lei Zhao, Qingling Hua, Lanqing Wang, Hongli Liu, Zhenyu Lin, Min Jin, Jing Wang, Pengfei Zhou, Kunyu Yang, Gang Wu, Dandan Yu, Dejun Zhang, Tao Zhang

Cell Death Dis. 2023 Feb; 14(2): 167. Published online 2023 Feb 27. doi: 10.1038/s41419-023-05644-z

PMCID:: PMC9971195

Abstract Article PDF–15M

Select item 91052359.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 816503010.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 773761011.

Receptor‐mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy

Amelia E Ohnstad, Jose M Delgado, Brian J North, Isha Nasa, Arminja N Kettenbach, Sebastian W Schultz, Christopher J Shoemaker

EMBO J. 2020 Dec 15; 39(24): e104948. Published online 2020 Nov 23. doi: 10.15252/embj.2020104948

PMCID:: PMC7737610

Abstract Article PDF–3.7M

Select item 742732712.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 647715213.

The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria

Benjamin J. Ravenhill, Keith B. Boyle, Natalia von Muhlinen, Cara J. Ellison, Glenn R. Masson, Elsje G. Otten, Agnes Foeglein, Roger Williams, Felix Randow

Mol Cell. 2019 Apr 18; 74(2): 320–329.e6. doi: 10.1016/j.molcel.2019.01.041

PMCID:: PMC6477152

Abstract Article

Select item 629825414.

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert

Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289

PMCID:: PMC6298254

Abstract Article PDF–1.4M

Select item 629488215.

Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1

Tao Fu, Jianping Liu, Yingli Wang, Xingqiao Xie, Shichen Hu, Lifeng Pan

Proc Natl Acad Sci U S A. 2018 Dec 11; 115(50): E11651–E11660. Published online 2018 Nov 20. doi: 10.1073/pnas.1811421115

PMCID:: PMC6294882

Abstract Article PDF–3.1M

Select item 626810016.

TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation

Elodie Lafont, Peter Draber, Eva Rieser, Matthias Reichert, Sebastian Kupka, Diego de Miguel, Helena Draberova, Anne von Mässenhausen, Amandeep Bhamra, Stephen Henderson, Katarzyna Wojdyla, Avigayil Chalk, Silvia Surinova, Andreas Linkermann, Henning Walczak

Nat Cell Biol. Author manuscript; available in PMC 2019 May 12.

Published in final edited form as: Nat Cell Biol. 2018 Dec; 20(12): 1389–1399. Published online 2018 Nov 12. doi: 10.1038/s41556-018-0229-6

PMCID:: PMC6268100

Abstract Article PDF–2.8M

Select item 588684417.

^AZI23'UTR is a new SLC6A3 downregulator associated with an epistatic protection against substance use disorders

Kefu Liu, Jinlong Yu, Juan Zhao, Yanhong Zhou, Nian Xiong, Jie Xu, Tao Wang, Richard L. Bell, Hong Qing, Zhicheng Lin

Mol Neurobiol. Author manuscript; available in PMC 2019 Jul 1.

Published in final edited form as: Mol Neurobiol. 2018 Jul; 55(7): 5611–5622. Published online 2017 Oct 5. doi: 10.1007/s12035-017-0781-2

PMCID:: PMC5886844

Abstract Article PDF–1.1M

Select item 569108318.

Autophagy acts through TRAF3 and RELB to regulate gene expression via antagonism of SMAD proteins

Alice C. Newman, Alain J. Kemp, Yvette Drabsch, Christian Behrends, Simon Wilkinson

Nat Commun. 2017; 8: 1537. Published online 2017 Nov 16. doi: 10.1038/s41467-017-00859-z

PMCID:: PMC5691083

Abstract Article PDF–2.3M

Select item 553358519.

The human cytoplasmic dynein interactome reveals novel activators of motility

William B Redwine, Morgan E DeSantis, Ian Hollyer, Zaw Min Htet, Phuoc Tien Tran, Selene K Swanson, Laurence Florens, Michael P Washburn, Samara L Reck-Peterson

eLife. 2017; 6: e28257. Published online 2017 Jul 18. doi: 10.7554/eLife.28257

PMCID:: PMC5533585

Abstract Article PDF–5.9M

Select item 553161120.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

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