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Select item 108687271.

Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates

Asif Ali, Rania Garde, Olivia C. Schaffer, Jared A. M. Bard, Kabir Husain, Samantha Keyport Kik, Kathleen A. Davis, Sofia Luengo-Woods, Maya G. Igarashi, D. Allan Drummond, Allison H. Squires, David Pincus

Nat Cell Biol. Author manuscript; available in PMC 2024 Feb 15.

Published in final edited form as: Nat Cell Biol. 2023 Nov; 25(11): 1691–1703. Published online 2023 Oct 16. doi: 10.1038/s41556-023-01253-2

PMCID:: PMC10868727

Abstract Article PDF–7.0M

Select item 107988582.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001383.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105517004.

Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability

Prashant K. Mishra, Wei-Chun Au, Pedro G. Castineira, Nazrin Ali, John Stanton, Lars Boeckmann, Yoshimitsu Takahashi, Michael Costanzo, Charles Boone, Kerry S. Bloom, Peter H. Thorpe, Munira A. Basrai

Mol Biol Cell. 2023 Sep 1; 34(10): ar99. Published online 2023 Aug 17. doi: 10.1091/mbc.E23-03-0108

PMCID:: PMC10551700

Abstract Article PDF–3.7M

Select item 105202605.

Two domains of Tim50 coordinate translocation of proteins across the two mitochondrial membranes

Marcel G Genge, Shalini Roy Chowdhury, Vít Dohnálek, Kaori Yunoki, Takashi Hirashima, Toshiya Endo, Pavel Doležal, Dejana Mokranjac

Life Sci Alliance. 2023 Dec; 6(12): e202302122. Published online 2023 Sep 25. doi: 10.26508/lsa.202302122

PMCID:: PMC10520260

Abstract Article PDF–3.1M

Select item 105113246.

Central role of Tim17 in mitochondrial presequence protein translocation

Laura F. Fielden, Jakob D. Busch, Sandra G. Merkt, Iniyan Ganesan, Conny Steiert, Hanna B. Hasselblatt, Jon V. Busto, Christophe Wirth, Nicole Zufall, Sibylle Jungbluth, Katja Noll, Julia M. Dung, Ludmila Butenko, Karina von der Malsburg, Hans-Georg Koch, Carola Hunte, Martin van der Laan, Nils Wiedemann

Nature. 2023; 621(7979): 627–634. Published online 2023 Aug 1. doi: 10.1038/s41586-023-06477-8

PMCID:: PMC10511324

Abstract Article PDF–27M

Select item 102977007.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 102922108.

Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin

Sanjeev Kumar Choudhry, Maxwell L. Neal, Song Li, Arti T. Navare, Trevor Van Eeuwen, Richard W. Wozniak, Fred D. Mast, Michael P. Rout, John D. Aitchison

J Cell Biol. 2023 Sep 4; 222(9): e202207060. Published online 2023 Jun 26. doi: 10.1083/jcb.202207060

PMCID:: PMC10292210

Abstract Article PDF–5.9M

Select item 95745149.

Elucidation of the interaction proteome of mitochondrial chaperone Hsp78 highlights its role in protein aggregation during heat stress

Witold Jaworek, Marc Sylvester, Giovanna Cenini, Wolfgang Voos

J Biol Chem. 2022 Oct; 298(10): 102494. Published online 2022 Sep 15. doi: 10.1016/j.jbc.2022.102494

PMCID:: PMC9574514

Abstract Article PDF–1.9M

Select item 928602310.

Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton

Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019

PMCID:: PMC9286023

Abstract Article

Select item 920981111.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 848251212.

Aim32 is a dual-localized 2Fe-2S mitochondrial protein that functions in redox quality control

Danyun Zhang, Owen R. Dailey, Daniel J. Simon, Kamilah Roca-Datzer, Yasaman Jami-Alahmadi, Mikayla S. Hennen, James A. Wohlschlegel, Carla M. Koehler, Deepa V. Dabir

J Biol Chem. 2021 Oct; 297(4): 101135. Published online 2021 Aug 28. doi: 10.1016/j.jbc.2021.101135

PMCID:: PMC8482512

Abstract Article PDF–5.0M

Select item 848154213.

Mapping protein interactions in the active TOM-TIM23 supercomplex

Ridhima Gomkale, Andreas Linden, Piotr Neumann, Alexander Benjamin Schendzielorz, Stefan Stoldt, Olexandr Dybkov, Markus Kilisch, Christian Schulz, Luis Daniel Cruz-Zaragoza, Blanche Schwappach, Ralf Ficner, Stefan Jakobs, Henning Urlaub, Peter Rehling

Nat Commun. 2021; 12: 5715. Published online 2021 Sep 29. doi: 10.1038/s41467-021-26016-1

PMCID:: PMC8481542

Abstract Article PDF–9.2M

Select item 772018314.

Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation

Aurore Sanchez, Céline Adam, Felix Rauh, Yann Duroc, Lepakshi Ranjha, Bérangère Lombard, Xiaojing Mu, Mélody Wintrebert, Damarys Loew, Alba Guarné, Stefano Gnan, Chun-Long Chen, Scott Keeney, Petr Cejka, Raphaël Guérois, Franz Klein, Jean-Baptiste Charbonnier, Valérie Borde

Proc Natl Acad Sci U S A. 2020 Dec 1; 117(48): 30577–30588. Published online 2020 Nov 16. doi: 10.1073/pnas.2013012117

PMCID:: PMC7720183

Abstract Article PDF–2.3M

Select item 741366715.

Mitochondrial volume fraction and translation duration impact mitochondrial mRNA localization and protein synthesis

Tatsuhisa Tsuboi, Matheus P Viana, Fan Xu, Jingwen Yu, Raghav Chanchani, Ximena G Arceo, Evelina Tutucci, Joonhyuk Choi, Yang S Chen, Robert H Singer, Susanne M Rafelski, Brian M Zid

eLife. 2020; 9: e57814. Published online 2020 Aug 7. doi: 10.7554/eLife.57814

PMCID:: PMC7413667

Abstract Article PDF–1.3M

Select item 735316416.

Mgr2 regulates mitochondrial preprotein import by associating with channel-forming Tim23 subunit

Srujan Kumar Matta, Abhishek Kumar, Patrick D’Silva

Mol Biol Cell. 2020 May 15; 31(11): 1112–1123. doi: 10.1091/mbc.E19-12-0677

PMCID:: PMC7353164

Abstract Article PDF–1.6M

Select item 652846717.

MitoCPR - a surveillance pathway that protects mitochondria in response to protein import stress

Hilla Weidberg, Angelika Amon

Science. Author manuscript; available in PMC 2019 May 21.

Published in final edited form as: Science. 2018 Apr 13; 360(6385): eaan4146. Published online 2018 Apr 12. doi: 10.1126/science.aan4146

PMCID:: PMC6528467

Abstract Article PDF–2.3M

Select item 637591718.

A mutagenesis analysis of Tim50, the major receptor of the TIM23 complex, identifies regions that affect its interaction with Tim23

Dana Dayan, May Bandel, Umut Günsel, Inbal Nussbaum, Gali Prag, Dejana Mokranjac, Walter Neupert, Abdussalam Azem

Sci Rep. 2019; 9: 2012. Published online 2019 Feb 14. doi: 10.1038/s41598-018-38353-1

PMCID:: PMC6375917

Abstract Article PDF–1.7M

Select item 628012419.

Recruitment of Cytosolic J-Proteins by TOM Receptors Promotes Mitochondrial Protein Biogenesis

Łukasz Opaliński, Jiyao Song, Chantal Priesnitz, Lena-Sophie Wenz, Silke Oeljeklaus, Bettina Warscheid, Nikolaus Pfanner, Thomas Becker

Cell Rep. 2018 Nov 20; 25(8): 2036–2043.e5. Published online 2018 Nov 20. doi: 10.1016/j.celrep.2018.10.083

PMCID:: PMC6280124

Abstract Article

Select item 616856420.

Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane

Alexander Benjamin Schendzielorz, Piotr Bragoszewski, Nataliia Naumenko, Ridhima Gomkale, Christian Schulz, Bernard Guiard, Agnieszka Chacinska, Peter Rehling

Nat Commun. 2018; 9: 4028. Published online 2018 Oct 2. doi: 10.1038/s41467-018-06492-8