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Select item 107034191.

Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves

Rachel Queen, Moira Crosier, Lorraine Eley, Janet Kerwin, Jasmin E. Turner, Jianshi Yu, Ahlam Alqahtani, Tamilvendhan Dhanaseelan, Lynne Overman, Hannah Soetjoadi, Richard Baldock, Jonathan Coxhead, Veronika Boczonadi, Alex Laude, Simon J. Cockell, Maureen A. Kane, Steven Lisgo, Deborah J. Henderson

PLoS Genet. 2023 Nov; 19(11): e1010777. Published online 2023 Nov 27. doi: 10.1371/journal.pgen.1010777

PMCID:: PMC10703419

Abstract Article PDF–9.6M

Select item 105473002.

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development

Bingruo Wu, Brian Wu, Sonia Benkaci, Lijie Shi, Pengfei Lu, Taeju Park, Bernice E. Morrow, Yidong Wang, Bin Zhou

J Am Heart Assoc. 2023 Sep 19; 12(18): e029683. Published online 2023 Sep 13. doi: 10.1161/JAHA.123.029683

PMCID:: PMC10547300

Abstract Article PDF–41M

Select item 105064133.

Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development

Jinshu Xu, Xianxiao Zhou, Ting Zhang, Bin Zhang, Pin-Xian Xu

Front Cell Dev Biol. 2023; 11: 1233317. Published online 2023 Sep 4. doi: 10.3389/fcell.2023.1233317

PMCID:: PMC10506413

Abstract Article PDF–7.2M

Select item 104787534.

Lem2 is essential for cardiac development by maintaining nuclear integrity

Jacob A Ross, Nathaly Arcos-Villacis, Edmund Battey, Cornelis Boogerd, Constanza Avalos Orellana, Emilie Marhuenda, Pamela Swiatlowska, Didier Hodzic, Fabrice Prin, Tim Mohun, Norman Catibog, Olga Tapia, Larry Gerace, Thomas Iskratsch, Ajay M Shah, Matthew J Stroud

Cardiovasc Res. 2023 Aug; 119(11): 2074–2088. Published online 2023 Apr 17. doi: 10.1093/cvr/cvad061

PMCID:: PMC10478753

Abstract Article PDF–33M

Select item 103872375.

DELE1 is protective for mitochondrial cardiomyopathy

Helen Huynh, Siting Zhu, Sharon Lee, Yutong Bao, Jing Pang, Anh Nguyen, Yusu Gu, Chao Chen, Kunfu Ouyang, Sylvia M. Evans, Xi Fang

J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Jul 30.

Published in final edited form as: J Mol Cell Cardiol. 2023 Feb; 175: 44–48. Published online 2022 Dec 17. doi: 10.1016/j.yjmcc.2022.12.003

PMCID:: PMC10387237

Abstract Article PDF–661K

Select item 103259826.

Molecular determinants of epithelial mesenchymal transition in mouse placenta and trophoblast stem cell

Shipra Kanti Jena, Shreya Das, Shreeta Chakraborty, Rupasri Ain

Sci Rep. 2023; 13: 10978. Published online 2023 Jul 6. doi: 10.1038/s41598-023-37977-2

PMCID:: PMC10325982

Abstract Article PDF–7.1M

Select item 101032627.

Tet2- and Tet3-Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment

Xiujie Liang, Tamas Aranyi, Jianfu Zhou, Yuting Guan, Hailong Hu, Hongbo Liu, Katalin Susztak

J Am Soc Nephrol. 2023 Apr; 34(4): 572–589. Published online 2022 Dec 15. doi: 10.1681/ASN.2022040460

PMCID:: PMC10103262

Abstract Article

Select item 100176578.

Mesenchyme-derived vertebrate lonesome kinase controls lung organogenesis by altering the matrisome

Salome M. Brütsch, Elizabeta Madzharova, Sophia Pantasis, Till Wüstemann, Selina Gurri, Heiko Steenbock, Amiq Gazdhar, Gisela Kuhn, Peter Angel, Saverio Bellusci, Jürgen Brinckmann, Ulrich auf dem Keller, Sabine Werner, Mattia R. Bordoli

Cell Mol Life Sci. 2023 Apr; 80(4): 89. Published online 2023 Mar 15. doi: 10.1007/s00018-023-04735-6

PMCID:: PMC10017657

Abstract Article PDF–5.2M

Select item 97188239.

DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal

Paola Cattaneo, Michael G. B. Hayes, Nina Baumgarten, Dennis Hecker, Sofia Peruzzo, Galip S. Aslan, Paolo Kunderfranco, Veronica Larcher, Lunfeng Zhang, Riccardo Contu, Gregory Fonseca, Simone Spinozzi, Ju Chen, Gianluigi Condorelli, Stefanie Dimmeler, Marcel H. Schulz, Sven Heinz, Nuno Guimarães-Camboa, Sylvia M. Evans

Nat Commun. 2022; 13: 7444. Published online 2022 Dec 2. doi: 10.1038/s41467-022-35070-2

PMCID:: PMC9718823

Abstract Article PDF–9.4M

Select item 968188710.

SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation

Lingjie Yan, Tao Zhang, Kai Wang, Zezhao Chen, Yuanxin Yang, Bing Shan, Qi Sun, Mengmeng Zhang, Yichi Zhang, Yedan Zhong, Nan Liu, Jinyang Gu, Daichao Xu

Nat Commun. 2022; 13: 7153. Published online 2022 Nov 22. doi: 10.1038/s41467-022-34993-0

PMCID:: PMC9681887

Abstract Article PDF–8.5M

Select item 968184311.

Angiopoietin-like 2 is essential to aortic valve development in mice

Pauline Labbé, Victoria Munoz Goyette, Nathalie Thorin-Trescases, Louis Villeneuve, Ines Desanlis, Constance Delwarde, Yan-Fen Shi, Cécile Martel, Carol Yu, Azadeh Alikashani, Maya Mamarbachi, Frédéric Lesage, Samuel Mathieu, Jean-Claude Tardif, Patrick Mathieu, Marie Kmita, Éric Thorin

Commun Biol. 2022; 5: 1277. Published online 2022 Nov 21. doi: 10.1038/s42003-022-04243-6

PMCID:: PMC9681843

Abstract Article PDF–13M

Select item 960442812.

Mother–Fetus Immune Cross-Talk Coordinates “Extrinsic”/“Intrinsic” Embryo Gene Expression Noise and Growth Stability

Tatyana Ivanovna Babochkina, Ludmila Alekseevna Gerlinskaya, Margarita Vladimirovna Anisimova, Galina Vladimirovna Kontsevaya, Natalia Aleksandrovna Feofanova, Aliya Konstantinovna Stanova, Mikhail Pavlovich Moshkin, Yuri Mikhailovich Moshkin

Int J Mol Sci. 2022 Oct; 23(20): 12467. Published online 2022 Oct 18. doi: 10.3390/ijms232012467

PMCID:: PMC9604428

Abstract Article PDF–2.3M

Select item 945909513.

Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects

Shaili D. Patel, Deepti Anand, Hozumi Motohashi, Fumiki Katsuoka, Masayuki Yamamoto, Salil A. Lachke

Front Cell Dev Biol. 2022; 10: 981893. Published online 2022 Aug 26. doi: 10.3389/fcell.2022.981893

PMCID:: PMC9459095

Abstract Article PDF–5.1M

Select item 901662014.

Vertebrate lonesome kinase modulates the hepatocyte secretome to prevent perivascular liver fibrosis and inflammation

Sophia Pantasis, Juliane Friemel, Salome Mirjam Brütsch, Zehan Hu, Sabrina Krautbauer, Gerhard Liebisch, Joern Dengjel, Achim Weber, Sabine Werner, Mattia Renato Bordoli

J Cell Sci. 2022 Apr 1; 135(7): jcs259243. Published online 2022 Apr 12. doi: 10.1242/jcs.259243

PMCID:: PMC9016620

Abstract Article

Select item 898800815.

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

Ann-Helen Rosendahl, Mia Monnius, Anu Laitala, Antti Railo, Ilkka Miinalainen, Ritva Heljasvaara, Joni M. Mäki, Johanna Myllyharju

J Biol Chem. 2022 Apr; 298(4): 101787. Published online 2022 Mar 2. doi: 10.1016/j.jbc.2022.101787

PMCID:: PMC8988008

Abstract Article PDF–6.1M

Select item 892627316.

Comparative therapeutic strategies for preventing aortic rupture in a mouse model of vascular Ehlers-Danlos syndrome

Anne Legrand, Charline Guery, Julie Faugeroux, Erika Fontaine, Carole Beugnon, Amélie Gianfermi, Irmine Loisel-Ferreira, Marie-Christine Verpont, Salma Adham, Tristan Mirault, Juliette Hadchouel, Xavier Jeunemaitre

PLoS Genet. 2022 Mar; 18(3): e1010059. Published online 2022 Mar 4. doi: 10.1371/journal.pgen.1010059