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Select item 114249781.

DDI2 protease controls embryonic development and inflammation via TCF11/NRF1

Monika Nedomova, Stefanie Haberecht-Müller, Sophie Möller, Simone Venz, Michaela Prochazkova, Jan Prochazka, Frantisek Sedlak, Kallayanee Chawengsaksophak, Elke Hammer, Petr Kasparek, Michael Adamek, Radislav Sedlacek, Jan Konvalinka, Elke Krüger, Klara Grantz Saskova

iScience. 2024 Oct 18; 27(10): 110893. Published online 2024 Sep 5. doi: 10.1016/j.isci.2024.110893

PMCID:: PMC11424978

Abstract Article PDF–6.1M

Select item 104876402.

Forced Hepatic Expression of NRF2 or NQO1 Impedes Hepatocyte Lipid Accumulation in a Lipodystrophy Mouse Model

Nobunao Wakabayashi, Yoko Yagishita, Tanvi Joshi, Thomas W. Kensler

Int J Mol Sci. 2023 Sep; 24(17): 13345. Published online 2023 Aug 28. doi: 10.3390/ijms241713345

PMCID:: PMC10487640

Abstract Article PDF–5.0M

Select item 96874553.

Maternal Calorie Restriction Induces a Transcriptional Cytoprotective Response in Embryonic Liver Partially Dependent on Nrf2

George I. Habeos, Fotini Filippopoulou, Evagelia E. Habeos, Electra Kalaitzopoulou, Marianna Skipitari, Polyxeni Papadea, George Lagoumintzis, Athanasios Niarchos, Christos D. Georgiou, Dionysios V. Chartoumpekis

Antioxidants (Basel) 2022 Nov; 11(11): 2274. Published online 2022 Nov 17. doi: 10.3390/antiox11112274

PMCID:: PMC9687455

Abstract Article PDF–2.0M

Select item 96298504.

Tanshinone functions as a coenzyme that confers gain of function of NQO1 to suppress ferroptosis

Tian-Xiang Wang, Kun-Long Duan, Zi-Xuan Huang, Zi-An Xue, Jun-Yun Liang, Yongjun Dang, Ao Zhang, Yue Xiong, Chunyong Ding, Kun-Liang Guan, Hai-Xin Yuan

Life Sci Alliance. 2023 Jan; 6(1): e202201667. Published online 2022 Nov 1. doi: 10.26508/lsa.202201667

PMCID:: PMC9629850

Abstract Article PDF–2.4M

Select item 93376735.

Antioxidative enzyme NAD(P)H quinone oxidoreductase 1 (NQO1) modulates the differentiation of Th17 cells by regulating ROS levels

Kyoko Nishida-Tamehiro, Akihiro Kimura, Takeshi Tsubata, Satoru Takahashi, Harumi Suzuki

PLoS One. 2022; 17(7): e0272090. Published online 2022 Jul 29. doi: 10.1371/journal.pone.0272090

PMCID:: PMC9337673

Abstract Article PDF–2.1M

Select item 89737886.

Hif1α-dependent hypoxia signaling contributes to the survival of deep-layer neurons and cortex formation in a mouse model

Daisuke Sakai, Takeru Sugawara, Tomonori Kurokawa, Yuki Murakami, Mitsuhiro Tomosugi, Hiroko Masuta, Hiromi Sakata-Haga, Toshihisa Hatta, Hiroki Shoji

Mol Brain. 2022; 15: 28. Published online 2022 Mar 31. doi: 10.1186/s13041-022-00911-0

PMCID:: PMC8973788

Abstract Article PDF–12M

Select item 87964937.

NAD(P)H: quinone oxidoreductase 1 attenuates oxidative stress and apoptosis by regulating Sirt1 in diabetic nephropathy

Duojun Qiu, Shan Song, Yuhan Wang, Yawei Bian, Ming Wu, Haijiang Wu, Yonghong Shi, Huijun Duan

J Transl Med. 2022; 20: 44. Published online 2022 Jan 28. doi: 10.1186/s12967-021-03197-3

PMCID:: PMC8796493

Abstract Article PDF–16M

Select item 83401398.

Activation of AhR-NQO1 Signaling Pathway Protects Against Alcohol-Induced Liver Injury by Improving Redox Balance

Haibo Dong, Liuyi Hao, Wenliang Zhang, Wei Zhong, Wei Guo, Ruichao Yue, Xinguo Sun, Zhanxiang Zhou

Cell Mol Gastroenterol Hepatol. 2021; 12(3): 793–811. Published online 2021 May 31. doi: 10.1016/j.jcmgh.2021.05.013

PMCID:: PMC8340139

Abstract Article PDF–8.1M

Select item 82420119.

Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy

Allison L. Fisher, Veena Sangkhae, Kamila Balušíková, Nicolaos J. Palaskas, Tomas Ganz, Elizabeta Nemeth

Nat Commun. 2021; 12: 4026. Published online 2021 Jun 29. doi: 10.1038/s41467-021-24333-z

PMCID:: PMC8242011

Abstract Article PDF–5.4M

Select item 810146910.

Docosahexanoic acid signals through the Nrf2–Nqo1 pathway to maintain redox balance and promote neurite outgrowth

Jennifer Drolet, Brodie Buchner-Duby, Morgan G. Stykel, Carla Coackley, Jing X. Kang, David W. L. Ma, Scott D. Ryan

Mol Biol Cell. 2021 Apr 1; 32(7): 511–520. doi: 10.1091/mbc.E20-09-0599

PMCID:: PMC8101469

Abstract Article PDF–1.5M

Select item 793877011.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 777257512.

A redox-mediated conformational change in NQO1 controls binding to microtubules and α-tubulin acetylation

David Siegel, Stephanie Bersie, Peter Harris, Andrea Di Francesco, Michael Armstrong, Nichole Reisdorph, Michel Bernier, Rafael de Cabo, Kristofer Fritz, David Ross

Redox Biol. 2021 Feb; 39: 101840. Published online 2020 Dec 18. doi: 10.1016/j.redox.2020.101840

PMCID:: PMC7772575

Abstract Article PDF–12M

Select item 757659613.

The potential roles of NAD(P)H:quinone oxidoreductase 1 in the development of diabetic nephropathy and actin polymerization

Sung-Je Moon, Jin Young Jeong, Jae-Hoon Kim, Dong-Hee Choi, Hyunsu Choi, Yoon-Kyung Chang, Ki Ryang Na, Kang Wook Lee, Chul-Ho Lee, Dae Eun Choi, Jung Hwan Hwang

Sci Rep. 2020; 10: 17735. Published online 2020 Oct 20. doi: 10.1038/s41598-020-74493-z

PMCID:: PMC7576596

Abstract Article PDF–2.3M

Select item 724420514.

Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia

Sofia Håglin, Anna Berghard, Staffan Bohm

J Neurosci. 2020 May 20; 40(21): 4116–4129. doi: 10.1523/JNEUROSCI.2468-19.2020

PMCID:: PMC7244205

Abstract Article PDF–6.1M

Select item 687542415.

Methane Alleviates Acetaminophen-Induced Liver Injury by Inhibiting Inflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Apoptosis through the Nrf2/HO-1/NQO1 Signaling Pathway

Yang Feng, Ruixia Cui, Zeyu Li, Xia Zhang, Yifan Jia, Xing Zhang, Jinghong Shi, Kai Qu, Chang Liu, Jingyao Zhang

Oxid Med Cell Longev. 2019; 2019: 7067619. Published online 2019 Nov 6. doi: 10.1155/2019/7067619

PMCID:: PMC6875424

Abstract Article PDF–2.3M

Select item 671854416.

Augmentation of cellular NAD⁺ by NQO1 enzymatic action improves age‐related hearing impairment

Hyung‐Jin Kim, Wa Cao, Gi‐Su Oh, SeungHoon Lee, AiHua Shen, Dipendra Khadka, Su‐Bin Lee, Subham Sharma, Seon Young Kim, Seong‐Kyu Choe, Tae Hwan Kwak, Jin‐Man Kim, Raekil Park, Hong‐Seob So

Aging Cell. 2019 Oct; 18(5): e13016. Published online 2019 Jul 28. doi: 10.1111/acel.13016

PMCID:: PMC6718544

Abstract Article PDF–2.0M

Select item 667219217.

Requirement for Slit-1 and Robo-2 in Zonal Segregation of Olfactory Sensory Neuron Axons in the Main Olfactory Bulb

Jin Hyung Cho, Manon Lépine, William Andrews, John Parnavelas, Jean-François Cloutier

J Neurosci. 2007 Aug 22; 27(34): 9094–9104. doi: 10.1523/JNEUROSCI.2217-07.2007

PMCID:: PMC6672192

Abstract Article PDF–872K

Select item 664208618.

NQO1 targeting prodrug triggers innate sensing to overcome checkpoint blockade resistance

Xiaoguang Li, Zhida Liu, Anli Zhang, Chuanhui Han, Aijun Shen, Lingxiang Jiang, David A. Boothman, Jian Qiao, Yang Wang, Xiumei Huang, Yang-Xin Fu

Nat Commun. 2019; 10: 3251. Published online 2019 Jul 19. doi: 10.1038/s41467-019-11238-1

PMCID:: PMC6642086

Abstract Article PDF–1.7M

Select item 663312619.

The Pattern of Glomerular Map Formation Defines Responsiveness to Aversive Odorants in Mice

Jin Hyung Cho, Janet E. A. Prince, Tyler Cutforth, Jean-François Cloutier

J Neurosci. 2011 May 25; 31(21): 7920–7926. doi: 10.1523/JNEUROSCI.2460-10.2011

PMCID:: PMC6633126

Abstract Article PDF–3.0M

Select item 661973420.

Goofy Coordinates the Acuity of Olfactory Signaling

Tomomi Kaneko-Goto, Yuki Sato, Sayako Katada, Emi Kinameri, Sei-ichi Yoshihara, Atsushi Nishiyori, Mitsuhiro Kimura, Hiroko Fujita, Kazushige Touhara, Randall R. Reed, Yoshihiro Yoshihara

J Neurosci. 2013 Aug 7; 33(32): 12987–12996. doi: 10.1523/JNEUROSCI.4948-12.2013

PMCID:: PMC6619734

Abstract Article PDF–4.5M

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