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Select item 113770411.

Syntaxin-6 delays prion protein fibril formation and prolongs the presence of toxic aggregation intermediates

Daljit Sangar, Elizabeth Hill, Kezia Jack, Mark Batchelor, Beenaben Mistry, Juan M Ribes, Graham S Jackson, Simon Mead, Jan Bieschke

eLife. 2024; 13: e83320. Published online 2024 Aug 7. doi: 10.7554/eLife.83320

PMCID:: PMC11377041

Abstract Article PDF–4.2M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 99382163.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Abstract Article PDF–5.3M

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 76156005.

Characterisation and prion transmission study in mice with genetic reduction of sporadic Creutzfeldt-Jakob disease risk gene Stx6

Emma Jones, Elizabeth Hill, Jacqueline Linehan, Tamsin Nazari, Adam Caulder, Gemma F. Codner, Marie Hutchison, Matthew Mackenzie, Michael Farmer, Thomas Coysh, Michael Wiggins De Oliveira, Huda Al-Doujaily, Malin Sandberg, Emmanuelle Viré, Thomas J. Cunningham, Emmanuel A. Asante, Sebastian Brandner, John Collinge, Simon Mead

Neurobiol Dis. Author manuscript; available in PMC 2024 Feb 6.

Published in final edited form as: Neurobiol Dis. 2024 Jan 1; 190: 106363. Published online 2023 Nov 22. doi: 10.1016/j.nbd.2023.106363

PMCID:: PMC7615600

Abstract Article PDF–12M

Select item 58258706.

The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival

Stefan Norlin, Vishal Parekh, Helena Edlund

Development. 2018 Jan 1; 145(1): dev154468. doi: 10.1242/dev.154468

PMCID:: PMC5825870

Abstract Article

Select item 44170487.

EARP, a multisubunit tethering complex involved in endocytic recycling

Christina Schindler, Yu Chen, Jing Pu, Xiaoli Guo, Juan S. Bonifacino

Nat Cell Biol. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: Nat Cell Biol. 2015 May; 17(5): 639–650. Published online 2015 Mar 23. doi: 10.1038/ncb3129

PMCID:: PMC4417048

Abstract Article PDF–2.9M

Select item 43279928.

Recycling of IRAP from the plasma membrane back to the insulin-responsive compartment requires the Q-SNARE syntaxin 6 but not the GGA clathrin adaptors

Robert T. Watson, Jeffrey E. Pessin

J Cell Sci. Author manuscript; available in PMC 2015 Feb 14.

Published in final edited form as: J Cell Sci. 2008 Apr 15; 121(0 8): 1243–1251. doi: 10.1242/jcs.017517

Correction in:: J Cell Sci, volume 121 on page 2275

PMCID:: PMC4327992

Abstract Article PDF–951K

Select item 41236539.

The C-terminus of GLUT4 targets the transporter to the perinuclear compartment but not to the insulin-responsive vesicles

Lin V. Li, Kyriaki Bakirtzi, Robert T. Watson, Jeffrey E. Pessin, Konstantin V. Kandror

Biochem J. Author manuscript; available in PMC 2014 Aug 6.

Published in final edited form as: Biochem J. 2009 Apr 1; 419(1): 105–112. doi: 10.1042/BJ20081448

PMCID:: PMC4123653

Abstract Article PDF–734K

Select item 357609610.

Role for Phospholipid Flippase Complex of ATP8A1 and CDC50A Proteins in Cell Migration

Utako Kato, Hironori Inadome, Masatoshi Yamamoto, Kazuo Emoto, Toshihide Kobayashi, Masato Umeda

J Biol Chem. 2013 Feb 15; 288(7): 4922–4934. Published online 2012 Dec 26. doi: 10.1074/jbc.M112.402701

PMCID:: PMC3576096

Abstract Article PDF–4.2M

Select item 353173611.

The Ubiquitin Ligase Synoviolin Up-regulates Amyloid β Production by Targeting a Negative Regulator of γ-Secretase, Rer1, for Degradation

Chiaki Tanabe, Tomoji Maeda, Kun Zou, Junjun Liu, Shuyu Liu, Toshihiro Nakajima, Hiroto Komano

J Biol Chem. 2012 Dec 28; 287(53): 44203–44211. Published online 2012 Nov 5. doi: 10.1074/jbc.M112.365296

PMCID:: PMC3531736

Abstract Article PDF–2.3M

Select item 346549412.

Cholesterol accumulation increases insulin granule size and impairs membrane trafficking

Jonathan S. Bogan, Yingke Xu, Mingming Hao

Traffic. Author manuscript; available in PMC 2013 Nov 1.

Published in final edited form as: Traffic. 2012 Nov; 13(11): 1466–1480. Published online 2012 Sep 13. doi: 10.1111/j.1600-0854.2012.01407.x

PMCID:: PMC3465494

Abstract Article PDF–4.1M

Select item 340974213.

Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis

Satoshi Somekawa, Keiichi Imagawa, Hisaki Hayashi, Masahide Sakabe, Tomoko Ioka, Genki E. Sato, Ken Inada, Takaaki Iwamoto, Toshio Mori, Shiro Uemura, Osamu Nakagawa, Yoshihiko Saito

Proc Natl Acad Sci U S A. 2012 Jul 24; 109(30): 12064–12069. Published online 2012 Jul 10. doi: 10.1073/pnas.1207210109

PMCID:: PMC3409742

Abstract Article PDF–2.1M

Select item 328533214.

Salmonella Acquires Lysosome-associated Membrane Protein 1 (LAMP1) on Phagosomes from Golgi via SipC Protein-mediated Recruitment of Host Syntaxin6

Richa Madan, Ruchir Rastogi, Seetharaman Parashuraman, Amitabha Mukhopadhyay

J Biol Chem. 2012 Feb 17; 287(8): 5574–5587. Published online 2011 Dec 21. doi: 10.1074/jbc.M111.286120

PMCID:: PMC3285332

Abstract Article PDF–3.1M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253416.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582