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Select item 110984861.

CCR5 promotes the migration of pathological CD8⁺ T cells to the leishmanial lesions

Laís Amorim Sacramento, Camila Farias Amorim, Claudia G. Lombana, Daniel Beiting, Fernanda Novais, Lucas P. Carvalho, Edgar M. Carvalho, Phillip Scott

PLoS Pathog. 2024 May; 20(5): e1012211. Published online 2024 May 6. doi: 10.1371/journal.ppat.1012211

PMCID:: PMC11098486

Abstract Article PDF–3.5M

Select item 110623762.

Microglial cytokines poison neuronal autophagy via CCR5, a druggable target

Beatrice Paola Festa, Farah H. Siddiqi, Maria Jimenez-Sanchez, David C. Rubinsztein

Autophagy. 2024; 20(4): 949–951. Published online 2023 Jun 26. doi: 10.1080/15548627.2023.2221921

PMCID:: PMC11062376

Abstract Article PDF–407K

Select item 110296433.

CCR5 in recruitment and activation of myeloid-derived suppressor cells in melanoma

Viktor Umansky, Carolin Blattner, Christoffer Gebhardt, Jochen Utikal

Cancer Immunol Immunother. 2017 Aug; 66(8): 1015–1023. Published online 2017 Apr 5. doi: 10.1007/s00262-017-1988-9

PMCID:: PMC11029643

Abstract Article PDF–831K

Select item 109170264.

CCR5 deficiency: Decreased neuronal resilience to oxidative stress and increased risk of vascular dementia

Benjamin B. Tournier, Silvia Sorce, Antoine Marteyn, Roberta Ghidoni, Luisa Benussi, Giuliano Binetti, François R Herrmann, Karl‐Heinz Krause, Dina Zekry

Alzheimers Dement. 2024 Jan; 20(1): 124–135. Published online 2023 Jul 25. doi: 10.1002/alz.13392

PMCID:: PMC10917026

Abstract Article PDF–2.6M

Select item 108601975.

Rapid protection against viral infections by chemokine-accelerated post-exposure vaccination

Annkristin Heine, Niels A. W. Lemmermann, Chrystel Flores, Janine Becker-Gotot, Natalio Garbi, Peter Brossart, Christian Kurts

Front Immunol. 2024; 15: 1338499. Published online 2024 Jan 29. doi: 10.3389/fimmu.2024.1338499

PMCID:: PMC10860197

Abstract Article PDF–1.5M

Select item 107212596.

CCR5 drives NK cell–associated airway damage in pulmonary ischemia-reperfusion injury

Jesse Santos, Ping Wang, Avishai Shemesh, Fengchun Liu, Tasha Tsao, Oscar A. Aguilar, Simon J. Cleary, Jonathan P. Singer, Ying Gao, Steven R. Hays, Jeffrey A. Golden, Lorriana Leard, Mary Ellen Kleinhenz, Nicholas A. Kolaitis, Rupal Shah, Aida Venado, Jasleen Kukreja, S. Sam Weigt, John A. Belperio, Lewis L. Lanier, Mark R. Looney, John R. Greenland, Daniel R. Calabrese

JCI Insight. 2023 Nov 8; 8(21): e173716. Published online 2023 Nov 8. doi: 10.1172/jci.insight.173716

PMCID:: PMC10721259

Abstract Article PDF–2.2M

Select item 106856307.

C–C chemokine receptor 5 is essential for conventional NK cell trafficking and liver injury in a murine hepatitis virus-induced fulminant hepatic failure model

Yun-Hui Liu, Lin Zhu, Zhong-Wei Zhang, Ting-Ting Liu, Qiu-Yu Cheng, Meng Zhang, Yu-Xin Niu, Lin Ding, Wei-Ming Yan, Xiao-Ping Luo, Qin Ning, Tao Chen

J Transl Med. 2023; 21: 865. Published online 2023 Nov 29. doi: 10.1186/s12967-023-04665-8

PMCID:: PMC10685630

Abstract Article PDF–14M

Select item 106819808.

Centrosome clustering control in osteoclasts through CCR5-mediated signaling

Ji-Won Lee, In-Hee Lee, Haruhisa Watanabe, Yunqing Liu, Kazuaki Sawada, Masashi Maekawa, Shunsuke Uehara, Yasuhiro Kobayashi, Yuuki Imai, Sek Won Kong, Tadahiro Iimura

Sci Rep. 2023; 13: 20813. Published online 2023 Nov 27. doi: 10.1038/s41598-023-48140-2

PMCID:: PMC10681980

Abstract Article PDF–8.1M

Select item 102918509.

CCR5 deficiency normalizes TIMP levels, working memory, and gamma oscillation power in APOE4 targeted replacement mice

Griffin A. Greco, Mitchell Rock, Matthew Amontree, Maria Fe Lanfranco, Holly Korthas, Sung Hyeok Hong, R. Scott Turner, G. William Rebeck, Katherine Conant

Neurobiol Dis. Author manuscript; available in PMC 2023 Jun 26.

Published in final edited form as: Neurobiol Dis. 2023 Apr; 179: 106057. Published online 2023 Mar 5. doi: 10.1016/j.nbd.2023.106057

PMCID:: PMC10291850

Abstract Article PDF–1.4M

Select item 1007222310.

CCL5-producing migratory dendritic cells guide CCR5⁺ monocytes into the draining lymph nodes

Kavita Rawat, Anita Tewari, Xin Li, Arlind B. Mara, William T. King, Sophie L. Gibbings, Chinaza F. Nnam, Fred W. Kolling, Bart N. Lambrecht, Claudia V. Jakubzick

J Exp Med. 2023 Jun 5; 220(6): e20222129. Published online 2023 Mar 22. doi: 10.1084/jem.20222129

PMCID:: PMC10072223

Abstract Article PDF–3.6M

Select item 1001596311.

CCL5/CCR5-mediated peripheral inflammation exacerbates blood‒brain barrier disruption after intracerebral hemorrhage in mice

Jie Lin, Ya Xu, Peiwen Guo, Yù-Jié Chen, Jiru Zhou, Min Xia, Binbin Tan, Xin Liu, Hua Feng, Yujie Chen

J Transl Med. 2023; 21: 196. Published online 2023 Mar 14. doi: 10.1186/s12967-023-04044-3

PMCID:: PMC10015963

Abstract Article PDF–9.5M

Select item 992532512.

TCRαβ⁺NK1.1^-CD4^-CD8^- double-negative T cells inhibit central and peripheral inflammation and ameliorate ischemic stroke in mice

Dan Tian, Yuhualei Pan, Yushang Zhao, Huan Wang, Yue Tian, Lu Yang, Wen Shi, Chengjie Zhang, Yanbing Zhu, Yongbo Zhang, Songlin Wang, Dong Zhang

Theranostics. 2023; 13(3): 896–909. Published online 2023 Jan 10. doi: 10.7150/thno.80307

PMCID:: PMC9925325

Abstract Article PDF–9.8M

Select item 983421813.

TGFβ1⁺CCR5⁺ neutrophil subset increases in bone marrow and causes age-related osteoporosis in male mice

Jinbo Li, Zhenqiang Yao, Xin Liu, Rong Duan, Xiangjiao Yi, Akram Ayoub, James O. Sanders, Addisu Mesfin, Lianping Xing, Brendan F. Boyce

Nat Commun. 2023; 14: 159. Published online 2023 Jan 11. doi: 10.1038/s41467-023-35801-z

PMCID:: PMC9834218

Abstract Article PDF–4.1M

Select item 979734214.

Mitochondrial dysfunction reactivates α-fetoprotein expression that drives copper-dependent immunosuppression in mitochondrial disease models

Kimberly A. Jett, Zakery N. Baker, Amzad Hossain, Aren Boulet, Paul A. Cobine, Sagnika Ghosh, Philip Ng, Orhan Yilmaz, Kris Barreto, John DeCoteau, Karen Mochoruk, George N. Ioannou, Christopher Savard, Sai Yuan, Osama H.M.H. Abdalla, Christopher Lowden, Byung-Eun Kim, Hai-Ying Mary Cheng, Brendan J. Battersby, Vishal M. Gohil, Scot C. Leary

J Clin Invest. 2023 Jan 3; 133(1): e154684. Published online 2023 Jan 3. doi: 10.1172/JCI154684

PMCID:: PMC9797342

Abstract Article PDF–3.1M

Select item 965656915.

Granulocytic MDSC with Deficient CCR5 Alleviates Lipogenesis and Inflammation in Nonalcoholic Fatty Liver Disease

Tzu-Chieh Liao, Jiung-Pang Huang, Yu-Ting Tsai, Wei-Ching Shih, Chi-Chang Juan, Po-Shiuan Hsieh, Li-Man Hung, Chao-Lan Yu

Int J Mol Sci. 2022 Nov; 23(21): 13048. Published online 2022 Oct 27. doi: 10.3390/ijms232113048

PMCID:: PMC9656569

Abstract Article PDF–3.7M

Select item 923660916.

Analysis of combinatorial chemokine receptor expression dynamics using multi-receptor reporter mice

Laura Medina-Ruiz, Robin Bartolini, Gillian J Wilson, Douglas P Dyer, Francesca Vidler, Catherine E Hughes, Fabian Schuette, Samantha Love, Marieke Pingen, Alan James Hayes, Jun Fu, Adrian Francis Stewart, Gerard J Graham

eLife. 2022; 11: e72418. Published online 2022 Jun 14. doi: 10.7554/eLife.72418

PMCID:: PMC9236609

Abstract Article PDF–8.8M

Select item 919719917.

CCR5 closes the temporal window for memory linking

Yang Shen, Miou Zhou, Denise Cai, Daniel Almeida Filho, Giselle Fernandes, Ying Cai, André F. de Sousa, Min Tian, Nury Kim, Jinsu Lee, Deanna Necula, Chengbin Zhou, Shuoyi Li, Shelbi Salinas, Andy Liu, Xiaoman Kang, Masakazu Kamata, Ayal Lavi, Shan Huang, Tawnie Silva, Won Do Heo, Alcino J. Silva

Nature. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Nature. 2022 Jun; 606(7912): 146–152. Published online 2022 May 25. doi: 10.1038/s41586-022-04783-1

PMCID:: PMC9197199

Abstract Article PDF–2.8M

Select item 884994518.

CCR5 maintains macrophages in the bone marrow and drives hematopoietic failure in a mouse model of severe aplastic anemia

Allison N. Seyfried, Amanda McCabe, Julianne N. P. Smith, Laura M. Calvi, Katherine C. MacNamara

Leukemia. Author manuscript; available in PMC 2022 Feb 16.

Published in final edited form as: Leukemia. 2021 Nov; 35(11): 3139–3151. Published online 2021 Mar 20. doi: 10.1038/s41375-021-01219-z

PMCID:: PMC8849945

Abstract Article PDF–2.2M

Select item 874516719.

Cysteine–Cysteine Motif Chemokine Receptor 5 Expression in Letrozole-Induced Polycystic Ovary Syndrome Mice

Kok-Min Seow, Pin-Shiou Liu, Kuo-Hu Chen, Chien-Wei Chen, Luen-Kui Chen, Chi-Hong Ho, Jiann-Loung Hwang, Peng-Hui Wang, Chi-Chang Juan

Int J Mol Sci. 2022 Jan; 23(1): 134. Published online 2021 Dec 23. doi: 10.3390/ijms23010134

PMCID:: PMC8745167

Abstract Article PDF–5.1M

Select item 873706620.

CC Chemokine Receptor 5 Targeted Nanoparticles Imaging the Progression and Regression of Atherosclerosis Using Positron Emission Tomography/Computed Tomography

Lisa Detering, Allison Abdilla, Hannah P. Luehmann, Jesse W. Williams, Li-Hao Huang, Deborah Sultan, Andrew Elvington, Gyu Seong Heo, Pamela K. Woodard, Robert J. Gropler, Gwendalyn J. Randolph, Craig J. Hawker, Yongjian Liu

Mol Pharm. Author manuscript; available in PMC 2022 Mar 1.

Published in final edited form as: Mol Pharm. 2021 Mar 1; 18(3): 1386–1396. Published online 2021 Feb 16. doi: 10.1021/acs.molpharmaceut.0c01183

PMCID:: PMC8737066

Abstract Article PDF–2.3M

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