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Items: 1 to 20 of 428

1.
A microbiome-dependent gut–brain pathway regulates motivation for exercise
Lenka Dohnalová, Patrick Lundgren, Jamie R. E. Carty, Nitsan Goldstein, Sebastian L. Wenski, Pakjira Nanudorn, Sirinthra Thiengmag, Kuei-Pin Huang, Lev Litichevskiy, Hélène C. Descamps, Karthikeyani Chellappa, Ana Glassman, Susanne Kessler, Jihee Kim, Timothy O. Cox, Oxana Dmitrieva-Posocco, Andrea C. Wong, Erik L. Allman, Soumita Ghosh, Nitika Sharma, Kasturi Sengupta, Belinda Cornes, Nitai Dean, Gary A. Churchill, Tejvir S. Khurana, Mark A. Sellmyer, Garret A. FitzGerald, Andrew D. Patterson, Joseph A. Baur, Amber L. Alhadeff, Eric J. N. Helfrich, Maayan Levy, J. Nicholas Betley, Christoph A. Thaiss
Nature. Author manuscript; available in PMC 2024 Jun 9.
Published in final edited form as: Nature. 2022 Dec; 612(7941): 739–747. Published online 2022 Dec 14. doi: 10.1038/s41586-022-05525-z
PMCID:
PMC11162758
AbstractArticlePDF–6.3M
2.
The CB1 receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls
Carlos Costas-Insua, Alba Hermoso-López, Estefanía Moreno, Carlos Montero-Fernández, Alicia Álvaro-Blázquez, Irene B Maroto, Andrea Sánchez-Ruiz, Rebeca Diez-Alarcia, Cristina Blázquez, Paula Morales, Enric I Canela, Vicent Casadó, Leyre Urigüen, Gertrudis Perea, Luigi Bellocchio, Ignacio Rodríguez-Crespo, Manuel Guzmán
EMBO Mol Med. 2024 Apr; 16(4): 755–783. Published online 2024 Mar 21. doi: 10.1038/s44321-024-00054-w
PMCID:
PMC11018632
AbstractArticlePDF–3.5M
3.
Beta cell specific cannabinoid 1 receptor deletion counteracts progression to hyperglycemia in non-obese diabetic mice
Kanikkai Raja Aseer, Caio Henrique Mazucanti, Jennifer F. O’Connell, Isabel González-Mariscal, Anjali Verma, Qin Yao, Christopher Dunn, Qing-Rong Liu, Josephine M. Egan, Máire E. Doyle
Mol Metab. 2024 Apr; 82: 101906. Published online 2024 Feb 28. doi: 10.1016/j.molmet.2024.101906
Correction in:
Mol Metab. 2024 Apr; 82: 101917.
PMCID:
PMC10940176
AbstractArticlePDF–3.8M
4.
The Expression and Functionality of CB1R-NMDAR Complexes Are Decreased in A Parkinson’s Disease Model
Irene Reyes-Resina, Jaume Lillo, Iu Raïch, Joan Biel Rebassa, Gemma Navarro
Int J Mol Sci. 2024 Mar; 25(5): 3021. Published online 2024 Mar 5. doi: 10.3390/ijms25053021
PMCID:
PMC10931566
AbstractArticlePDF–3.9M
5.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
6.
Endocannabinoid release at ventral hippocampal-amygdala synapses regulates stress-induced behavioral adaptation
Veronika Kondev, Mustafa Najeed, Farhana Yasmin, Amanda Morgan, Niharika Loomba, Keenan Johnson, Danielle N. Adank, Ao Dong, Eric Delpire, Yulong Li, Danny Winder, Brad A. Grueter, Sachin Patel
Cell Rep. Author manuscript; available in PMC 2024 Feb 6.
Published in final edited form as: Cell Rep. 2023 Sep 26; 42(9): 113027. Published online 2023 Sep 12. doi: 10.1016/j.celrep.2023.113027
PMCID:
PMC10846613
AbstractArticlePDF–1.3M
7.
Opposing retrograde and astrocyte-dependent endocannabinoid signaling mechanisms regulate lateral habenula synaptic transmission
Nathan D. Winters, Veronika Kondev, Niharika Loomba, Eric Delpire, Brad A. Grueter, Sachin Patel
Cell Rep. Author manuscript; available in PMC 2024 Feb 6.
Published in final edited form as: Cell Rep. 2023 Mar 28; 42(3): 112159. Published online 2023 Feb 26. doi: 10.1016/j.celrep.2023.112159
PMCID:
PMC10846612
AbstractArticlePDF–1.3M
8.
Inhibition of cannabinoid degradation enhances hippocampal contextual fear memory and exhibits anxiolytic effects
Jinming Zhang, Junmin Zhang, Ruiqi Yuan, Wenxin Han, Yuan Chang, Lingyang Kong, Chunling Wei, Qiaohua Zheng, Xingchao Zhu, Zhiqiang Liu, Wei Ren, Jing Han
iScience. 2024 Feb 16; 27(2): 108919. Published online 2024 Jan 15. doi: 10.1016/j.isci.2024.108919
PMCID:
PMC10839683
AbstractArticlePDF–4.4M
9.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
10.
Role of CB1 Cannabinoid Receptors in Vascular Responses and Vascular Remodeling of the Aorta in Female Mice
Bálint Bányai, Zsolt Vass, Stella Kiss, Anikó Balogh, Dóra Brandhuber, Gellért Karvaly, Krisztián Kovács, György L. Nádasy, László Hunyady, Gabriella Dörnyei, Eszter Mária Horváth, Mária Szekeres
Int J Mol Sci. 2023 Nov; 24(22): 16429. Published online 2023 Nov 17. doi: 10.3390/ijms242216429
PMCID:
PMC10671338
AbstractArticlePDF–3.6M
11.
Microglial cannabinoid receptor type 1 mediates social memory deficits in mice produced by adolescent THC exposure and 16p11.2 duplication
Yuto Hasegawa, Juhyun Kim, Gianluca Ursini, Yan Jouroukhin, Xiaolei Zhu, Yu Miyahara, Feiyi Xiong, Samskruthi Madireddy, Mizuho Obayashi, Beat Lutz, Akira Sawa, Solange P. Brown, Mikhail V. Pletnikov, Atsushi Kamiya
Nat Commun. 2023; 14: 6559. Published online 2023 Oct 25. doi: 10.1038/s41467-023-42276-5
PMCID:
PMC10600150
AbstractArticlePDF–4.8M
12.
ADOLESCENT EXPOSURE TO LOW-DOSE THC DISRUPTS ENERGY BALANCE AND ADIPOSE ORGAN HOMEOSTASIS IN ADULTHOOD
Lin Lin, Kwang-Mook Jung, Hye-Lim Lee, Johnny Le, Georgia Colleluori, Courtney Wood, Francesca Palese, Erica Squire, Jade Ramirez, Shiqi Su, Alexa Torrens, Yannick Fotio, Lingyi Tang, Clinton Yu, Qin Yang, Lan Huang, Nicholas DiPatrizio, Cholsoon Jang, Saverio Cinti, Daniele Piomelli
Cell Metab. Author manuscript; available in PMC 2024 Jul 11.
Published in final edited form as: Cell Metab. 2023 Jul 11; 35(7): 1227–1241.e7. Published online 2023 Jun 1. doi: 10.1016/j.cmet.2023.05.002
PMCID:
PMC10524841
AbstractArticlePDF–2.8M
13.
Cannabinoid receptor type 1 (CB1R) inhibits hypothalamic leptin signaling via β-arrestin1 in complex with TC-PTP and STAT3
Gergő Szanda, Tony Jourdan, Éva Wisniewski, Resat Cinar, Grzegorz Godlewski, Anikó Rajki, Jie Liu, Lee Chedester, Bence Szalai, András Dávid Tóth, Eszter Soltész-Katona, László Hunyady, Asuka Inoue, Viktória Bea Horváth, András Spät, Joseph Tam, George Kunos
iScience. 2023 Jul 21; 26(7): 107207. Published online 2023 Jun 25. doi: 10.1016/j.isci.2023.107207
PMCID:
PMC10392084
AbstractArticlePDF–4.3M
14.
Control of a hippocampal recurrent excitatory circuit by cannabinoid receptor-interacting protein Gap43
Irene B. Maroto, Carlos Costas-Insua, Coralie Berthoux, Estefanía Moreno, Andrea Ruiz-Calvo, Carlos Montero-Fernández, Andrea Macías-Camero, Ricardo Martín, Nuria García-Font, José Sánchez-Prieto, Giovanni Marsicano, Luigi Bellocchio, Enric I. Canela, Vicent Casadó, Ismael Galve-Roperh, Ángel Núñez, David Fernández de Sevilla, Ignacio Rodríguez-Crespo, Pablo E. Castillo, Manuel Guzmán
Nat Commun. 2023; 14: 2303. Published online 2023 Apr 21. doi: 10.1038/s41467-023-38026-2
PMCID:
PMC10121561
AbstractArticlePDF–3.1M
15.
Somatic and terminal CB1 receptors are differentially coupled to voltage-gated sodium channels in neocortical neurons
Luke J. Steiger, Timur Tsintsadze, Glynis B. Mattheisen, Stephen M. Smith
Cell Rep. Author manuscript; available in PMC 2023 Apr 16.
Published in final edited form as: Cell Rep. 2023 Mar 28; 42(3): 112247. Published online 2023 Mar 17. doi: 10.1016/j.celrep.2023.112247
PMCID:
PMC10106091
AbstractArticlePDF–3.0M
16.
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes
Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x
PMCID:
PMC9938216
AbstractArticlePDF–5.3M
17.
Cannabinoid receptor 2 plays a pro-tumorigenic role in non-small cell lung cancer by limiting anti-tumor activity of CD8+ T and NK cells
Arailym Sarsembayeva, Melanie Kienzl, Eva Gruden, Dusica Ristic, Kathrin Maitz, Paulina Valadez-Cosmes, Ana Santiso, Carina Hasenoehrl, Luka Brcic, Jörg Lindenmann, Julia Kargl, Rudolf Schicho
Front Immunol. 2022; 13: 997115. Published online 2023 Jan 9. doi: 10.3389/fimmu.2022.997115
PMCID:
PMC9868666
AbstractArticlePDF–9.5M
18.
Cannabinoid CB1 Receptors Are Expressed in a Subset of Dopamine Neurons and Underlie Cannabinoid-Induced Aversion, Hypoactivity, and Anxiolytic Effects in Mice
Xiao Han, Ying Liang, Briana Hempel, Chloe J. Jordan, Hui Shen, Guo-Hua Bi, Jin Li, Zheng-Xiong Xi
J Neurosci. 2023 Jan 18; 43(3): 373–385. doi: 10.1523/JNEUROSCI.1493-22.2022
PMCID:
PMC9864584
AbstractArticlePDF–5.4M
19.
Hippocampal Deletion of CB1 Receptor Impairs Social Memory and Leads to Age-Related Changes in the Hippocampus of Adult Mice
Michela Palmisano, Alessandra Gargano, Bolanle Fatimat Olabiyi, Beat Lutz, Andras Bilkei-Gorzo
Int J Mol Sci. 2023 Jan; 24(1): 26. Published online 2022 Dec 20. doi: 10.3390/ijms24010026
PMCID:
PMC9819823
AbstractArticlePDF–83M
20.
An astrocytic signaling loop for frequency-dependent control of dendritic integration and spatial learning
Kirsten Bohmbach, Nicola Masala, Eva M. Schönhense, Katharina Hill, André N. Haubrich, Andreas Zimmer, Thoralf Opitz, Heinz Beck, Christian Henneberger
Nat Commun. 2022; 13: 7932. Published online 2022 Dec 24. doi: 10.1038/s41467-022-35620-8
PMCID:
PMC9789958
AbstractArticlePDF–3.3M

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