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Items: 1 to 20 of 49

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis
Pengfei Guo, Rebecca C Lim, Keshari Rajawasam, Tiffany Trinh, Hong Sun, Hui Zhang
eLife. 2024; 13: e86168. Published online 2024 Feb 12. doi: 10.7554/eLife.86168
PMCID:
PMC10901513
AbstractArticlePDF–9.2M
3.
Gata2-regulated Gfi1b expression controls endothelial programming during endothelial-to-hematopoietic transition
Cansu Koyunlar, Emanuele Gioacchino, Disha Vadgama, Hans de Looper, Joke Zink, Mariette N. D. ter Borg, Remco Hoogenboezem, Marije Havermans, Mathijs A. Sanders, Eric Bindels, Elaine Dzierzak, Ivo P. Touw, Emma de Pater
Blood Adv. 2023 May 23; 7(10): 2082–2093. Published online 2023 Jan 20. doi: 10.1182/bloodadvances.2022008019
PMCID:
PMC10196789
AbstractArticlePDF–2.6M
4.
GFI1B acts as a metabolic regulator in hematopoiesis and acute myeloid leukemia
Longlong Liu, Pradeep Kumar Patnana, Xiaoqing Xie, Daria Frank, Subbaiah Chary Nimmagadda, Minhua Su, Donghua Zhang, Thorsten Koenig, Frank Rosenbauer, Marie Liebmann, Luisa Klotz, Wendan Xu, Jan Vorwerk, Felix Neumann, Jana Hüve, Andreas Unger, Jürgen Günther Okun, Bertram Opalka, Cyrus Khandanpour
Leukemia. 2022; 36(9): 2196–2207. Published online 2022 Jul 8. doi: 10.1038/s41375-022-01635-9
PMCID:
PMC9417998
AbstractArticlePDF–4.6M
5.
Differential Etv2 threshold requirement for endothelial and erythropoietic development
Tanvi Sinha, Kelly Lammerts van Bueren, Diane E. Dickel, Ivana Zlatanova, Reuben Thomas, Carlos O. Lizama, Shan-Mei Xu, Ann C. Zovein, Kohta Ikegami, Ivan P. Moskowitz, Katherine S. Pollard, Len A. Pennacchio, Brian L. Black
Cell Rep. Author manuscript; available in PMC 2022 Jun 16.
Published in final edited form as: Cell Rep. 2022 May 31; 39(9): 110881. doi: 10.1016/j.celrep.2022.110881
PMCID:
PMC9203129
AbstractArticlePDF–2.0M
6.
Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE
Muhammad Zaki Hidayatullah Fadlullah, Wen Hao Neo, Michael Lie-a-ling, Roshana Thambyrajah, Rahima Patel, Renaud Mevel, Irène Aksoy, Nam Do Khoa, Pierre Savatier, Laura Fontenille, Syed Murtuza Baker, Magnus Rattray, Valerie Kouskoff, Georges Lacaud
Blood. 2022 Jan 20; 139(3): 343–356. doi: 10.1182/blood.2020007885
PMCID:
PMC9159109
AbstractArticle
7.
Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient
Satomi Yogosawa, Makiko Ohkido, Takuro Horii, Yasumasa Okazaki, Jun Nakayama, Saishu Yoshida, Shinya Toyokuni, Izuho Hatada, Mitsuru Morimoto, Kiyotsugu Yoshida
Commun Biol. 2021; 4: 1204. Published online 2021 Oct 20. doi: 10.1038/s42003-021-02734-6
PMCID:
PMC8528819
AbstractArticlePDF–3.6M
8.
Dominant negative Gfi1b mutations cause moderate thrombocytopenia and an impaired stress thrombopoiesis associated with mild erythropoietic abnormalities in mice
Hugues Beauchemin, Peiman Shooshtharizadeh, Jordan Pinder, Graham Dellaire, Tarik Möröy
Haematologica. 2020 Oct 1; 105(10): 2457–2470. Published online 2019 Nov 21. doi: 10.3324/haematol.2019.222596
PMCID:
PMC7556681
AbstractArticlePDF–5.5M
9.
The Taste Receptor TAS1R3 Regulates Small Intestinal Tuft Cell Homeostasis
Michael R. Howitt, Y. Grace Cao, Matthew B. Gologorsky, Jessica A. Li, Adam L. Haber, Moshe Biton, Jessica Lang, Monia Michaud, Aviv Regev, Wendy S. Garrett
Immunohorizons. Author manuscript; available in PMC 2020 May 4.
Published in final edited form as: Immunohorizons. 2020 Jan 24; 4(1): 23–32. Published online 2020 Jan 24. doi: 10.4049/immunohorizons.1900099
PMCID:
PMC7197368
AbstractArticlePDF–1.5M
10.
Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes
Peiman Shooshtarizadeh, Anne Helness, Charles Vadnais, Nelleke Brouwer, Hugues Beauchemin, Riyan Chen, Halil Bagci, Frank J. T. Staal, Jean-François Coté, Tarik Möröy
Nat Commun. 2019; 10: 1270. Published online 2019 Mar 20. doi: 10.1038/s41467-019-09273-z
PMCID:
PMC6426870
AbstractArticlePDF–2.3M
11.
Origin of the brush cell lineage in the mouse intestinal epithelium
Matthew Bjerknes, Cyrus Khandanpour, Tarik Möröy, Tomoyuki Fujiyama, Mikio Hoshino, Tiemo J. Klisch, Qian Ding, Lin Gan, Jiafang Wang, Martín G. Martín, Hazel Cheng
Dev Biol. Author manuscript; available in PMC 2018 Jul 17.
Published in final edited form as: Dev Biol. 2012 Feb 15; 362(2): 194–218. Published online 2011 Dec 13. doi: 10.1016/j.ydbio.2011.12.009
PMCID:
PMC6050067
AbstractArticlePDF–4.1M
12.
Tropism for tuft cells determines immune promotion of norovirus pathogenesis
Craig B. Wilen, Sanghyun Lee, Lee-Yang Hsieh, Robert C. Orchard, Chandni Desai, Barry L. Hykes, Jr, Michael R. McAllaster, Dale R. Balce, Taylor Feehley, Jonathan R. Brestoff, Christina A. Hickey, Christine C. Yokoyama, Ya-Ting Wang, Donna A. MacDuff, Darren Kreamalmayer, Michael R. Howitt, Jessica A. Neil, Ken Cadwell, Paul M. Allen, Scott A. Handley, Menno van Lookeren Campagne, Megan T. Baldridge, Herbert W. Virgin
Science. Author manuscript; available in PMC 2018 Oct 13.
Published in final edited form as: Science. 2018 Apr 13; 360(6385): 204–208. doi: 10.1126/science.aar3799
PMCID:
PMC6039974
AbstractArticlePDF–933K
13.
In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells by Gfi1b, c-Fos, and Gata2 Overexpression within Teratoma
Masao Tsukada, Yasunori Ota, Adam C. Wilkinson, Hans J. Becker, Motomi Osato, Hiromitsu Nakauchi, Satoshi Yamazaki
Stem Cell Reports. 2017 Oct 10; 9(4): 1024–1033. Published online 2017 Sep 21. doi: 10.1016/j.stemcr.2017.08.010
PMCID:
PMC5639260
AbstractArticlePDF–2.5M
14.
Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut
Michael R. Howitt, Sydney Lavoie, Monia Michaud, Arthur M. Blum, Sara V. Tran, Joel V. Weinstock, Carey Ann Gallini, Kevin Redding, Robert F. Margolskee, Lisa C. Osborne, David Artis, Wendy S. Garrett
Science. Author manuscript; available in PMC 2017 Jul 26.
Published in final edited form as: Science. 2016 Mar 18; 351(6279): 1329–1333. Published online 2016 Feb 4. doi: 10.1126/science.aaf1648
PMCID:
PMC5528851
AbstractArticlePDF–812K
15.
Gfi1b controls integrin signaling-dependent cytoskeleton dynamics and organization in megakaryocytes
Hugues Beauchemin, Peiman Shooshtarizadeh, Charles Vadnais, Lothar Vassen, Yves D Pastore, Tarik Möröy
Haematologica. 2017 Mar; 102(3): 484–497. Prepublished online 2017 Jan 9. doi: 10.3324/haematol.2016.150375
PMCID:
PMC5394960
AbstractArticlePDF–5.3M
16.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
17.
The Hemogenic Competence of Endothelial Progenitors Is Restricted by Runx1 Silencing during Embryonic Development
Alexia Eliades, Sarah Wareing, Elli Marinopoulou, Muhammad Z.H. Fadlullah, Rahima Patel, Joanna B. Grabarek, Berenika Plusa, Georges Lacaud, Valerie Kouskoff
Cell Rep. 2016 Jun 7; 15(10): 2185–2199. Published online 2016 May 26. doi: 10.1016/j.celrep.2016.05.001
PMCID:
PMC4906370
AbstractArticle
18.
Reciprocal regulation of alternative lineages by Rgs18 and its transcriptional repressor Gfi1b
Ananya Sengupta, Ghanshyam Upadhyay, Sayani Sen, Shireen Saleque
J Cell Sci. 2016 Jan 1; 129(1): 145–154. doi: 10.1242/jcs.177519
PMCID:
PMC4732296
AbstractArticle
19.
GFI1B, EVI5, MYB—Additional genes that cooperate with the human BCL6 gene to promote the development of lymphomas
Beverly W. Baron, John Anastasi, Juraj Bies, Poluru L. Reddy, Loren Joseph, Michael J. Thirman, Kristen Wroblewski, Linda Wolff, Joseph M. Baron
Blood Cells Mol Dis. Author manuscript; available in PMC 2014 Dec 21.
Published in final edited form as: Blood Cells Mol Dis. 2014 Jan; 52(1): 68–75. Published online 2013 Jul 30. doi: 10.1016/j.bcmd.2013.07.003
PMCID:
PMC4272826
AbstractArticlePDF–1.2M
20.
Interferon Regulatory Factor 8 (IRF8) Interacts with the B Cell Lymphoma 6 (BCL6) Corepressor BCOR
Jeongheon Yoon, Xianxum Feng, Yong-Soo Kim, Dong-Mi Shin, Katerina Hatzi, Hongsheng Wang, Herbert C. Morse, III
J Biol Chem. 2014 Dec 5; 289(49): 34250–34257. Published online 2014 Oct 20. doi: 10.1074/jbc.M114.571182
PMCID:
PMC4256356
AbstractArticlePDF–1.2M

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