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Select item 111138421.

Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth

Daniela De Zio, Francesca Molinari, Salvatore Rizza, Lucia Gatta, Maria Teresa Ciotti, Anna Maria Salvatore, Søs Grønbæk Mathiassen, Andrzej W. Cwetsch, Giuseppe Filomeni, Giuseppe Rosano, Elisabetta Ferraro

Cell Mol Life Sci. 2015 Nov; 72(21): 4173–4191. Published online 2015 May 15. doi: 10.1007/s00018-015-1927-x

PMCID:: PMC11113842

Abstract Article PDF–1.8M

Select item 110366402.

Loss of AMPK activity induces organelle dysfunction and oxidative stress during oocyte aging

Lin-Lin Hu, Mei-Hua Liao, Ya-Xi Liu, Chun-Hua Xing, Lan-Lan Nong, Feng-Lian Yang, Shao-Chen Sun

Biol Direct. 2024; 19: 29. Published online 2024 Apr 23. doi: 10.1186/s13062-024-00471-4

PMCID:: PMC11036640

Abstract Article PDF–11M

Select item 109580333.

Marine Lanfranchi, Sozerko Yandiev, Géraldine Meyer-Dilhet, Salma Ellouze, Martijn Kerkhofs, Raphael Dos Reis, Audrey Garcia, Camille Blondet, Alizée Amar, Anita Kneppers, Hélène Polvèche, Damien Plassard, Marc Foretz, Benoit Viollet, Kei Sakamoto, Rémi Mounier, Cyril F. Bourgeois, Olivier Raineteau, Evelyne Goillot, Julien Courchet

Nat Commun. 2024; 15: 2487. Published online 2024 Mar 21. doi: 10.1038/s41467-024-46146-6

PMCID:: PMC10958033

Abstract Article PDF–5.0M

Select item 109238674.

Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo

Daniel M. Virga, Stevie Hamilton, Bertha Osei, Abigail Morgan, Parker Kneis, Emiliano Zamponi, Natalie J. Park, Victoria L. Hewitt, David Zhang, Kevin C. Gonzalez, Fiona M. Russell, D. Grahame Hardie, Julien Prudent, Erik Bloss, Attila Losonczy, Franck Polleux, Tommy L. Lewis, Jr

Nat Commun. 2024; 15: 2142. Published online 2024 Mar 8. doi: 10.1038/s41467-024-46463-w

PMCID:: PMC10923867

Abstract Article PDF–7.3M

Select item 109176605.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 109064576.

ZNFX1 promotes AMPK-mediated autophagy against Mycobacterium tuberculosis by stabilizing Prkaa2 mRNA

Honglin Liu, Zhenyu Han, Liru Chen, Jing Zhang, Zhanqing Zhang, Yaoxin Chen, Feichang Liu, Ke Wang, Jieyu Liu, Na Sai, Xinying Zhou, Chaoying Zhou, Shengfeng Hu, Qian Wen, Li Ma

JCI Insight. 2024 Jan 9; 9(1): e171850. Published online 2024 Jan 9. doi: 10.1172/jci.insight.171850

PMCID:: PMC10906457

Abstract Article PDF–4.5M

Select item 108420267.

Essential role of Mg²⁺ in mouse preimplantation embryo development revealed by TRPM7 chanzyme-deficient gametes

Neha Gupta, Cristina Soriano-Úbeda, Paula Stein, Virginia Savy, Brian N. Papas, Goli Ardestani, Ingrid Carvacho, Dominique Alfandari, Carmen J. Williams, Rafael A. Fissore

Cell Rep. Author manuscript; available in PMC 2024 Feb 5.

Published in final edited form as: Cell Rep. 2023 Oct 31; 42(10): 113232. Published online 2023 Oct 11. doi: 10.1016/j.celrep.2023.113232

PMCID:: PMC10842026

Abstract Article PDF–3.0M

Select item 107989788.

AMPKα2 regulates fasting-induced hyperketonemia by suppressing SCOT ubiquitination and degradation

Lingxue Zhang, Yanqiao Lu, Junqing An, Yin Wu, Zhixue Liu, Ming-Hui Zou

Sci Rep. 2024; 14: 1713. Published online 2024 Jan 19. doi: 10.1038/s41598-023-49991-5

PMCID:: PMC10798978

Abstract Article PDF–1.6M

Select item 107165529.

Chronic AMPK inactivation slows SHH medulloblastoma progression by inhibiting mTORC1 signaling and depleting tumor stem cells

Daniel Shiloh Malawsky, Taylor Dismuke, Hedi Liu, Ethan Castellino, Jay Brenman, Biplab Dasgupta, Andrey Tikunov, Timothy R. Gershon

iScience. 2023 Dec 15; 26(12): 108443. Published online 2023 Nov 14. doi: 10.1016/j.isci.2023.108443

PMCID:: PMC10716552

Abstract Article PDF–5.9M

Select item 1070085410.

AMPKα2 is a skeletal muscle stem cell intrinsic regulator of myonuclear accretion

Anita Kneppers, Sabrina Ben Larbi, Marine Theret, Audrey Saugues, Carole Dabadie, Linda Gsaier, Arnaud Ferry, Philipp Rhein, Julien Gondin, Kei Sakamoto, Rémi Mounier

iScience. 2023 Dec 15; 26(12): 108343. Published online 2023 Oct 26. doi: 10.1016/j.isci.2023.108343

PMCID:: PMC10700854

Abstract Article PDF–4.7M

Select item 1052063711.

NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte‐to‐Embryo Transition

Tie‐Gang Meng, Jia‐Ni Guo, Liu Zhu, Yike Yin, Feng Wang, Zhi‐Ming Han, Lei Lei, Xue‐Shan Ma, Yue Xue, Wei Yue, Xiao‐Qing Nie, Zheng‐Hui Zhao, Hong‐Yong Zhang, Si‐Min Sun, Ying‐Chun Ouyang, Yi Hou, Heide Schatten, Zhenyu Ju, Xiang‐Hong Ou, Zhen‐Bo Wang, Catherine C. L. Wong, Zhonghan Li, Qing‐Yuan Sun

Adv Sci (Weinh) 2023 Sep; 10(27): 2301940. Published online 2023 Jul 26. doi: 10.1002/advs.202301940

PMCID:: PMC10520637

Abstract Article PDF–6.6M

Select item 1012710512.

Alpha-SNAP (M105I) mutation promotes neuronal differentiation of neural stem/progenitor cells through overactivation of AMPK

Felipe A. Bustamante-Barrientos, Maxs Méndez-Ruette, Luis Molina, Tania Koning, Pamela Ehrenfeld, Carlos B. González, Ursula Wyneken, Roberto Henzi, Luis Federico Bátiz

Front Cell Dev Biol. 2023; 11: 1061777. Published online 2023 Apr 11. doi: 10.3389/fcell.2023.1061777

PMCID:: PMC10127105

Abstract Article PDF–4.2M

Select item 996829713.

Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation

Eun-Ji Park, Hyun-Soo Kim, Do-Hyoung Lee, Su-Min Kim, Joon-Sup Yoon, Ji-Min Lee, Se Jin Im, Ho Lee, Min-Woo Lee, Chang-Woo Lee

Nat Commun. 2023; 14: 1097. Published online 2023 Feb 25. doi: 10.1038/s41467-023-36836-y

PMCID:: PMC9968297

Abstract Article PDF–4.4M

Select item 994119914.

Quantification and Proteomic Characterization of β-Hydroxybutyrylation Modification in the Hearts of AMPKα2 Knockout Mice

Wen-jing Ding, Xue-hui Li, Cong-min Tang, Xue-chun Yang, Yan Sun, Yi-ping Song, Ming-ying Ling, Rong Yan, Hai-qing Gao, Wen-hua Zhang, Na Yu, Jun-chao Feng, Zhen Zhang, Yan-qiu Xing

Mol Cell Proteomics. 2023 Feb; 22(2): 100494. Published online 2023 Jan 5. doi: 10.1016/j.mcpro.2023.100494

PMCID:: PMC9941199

Abstract Article PDF–3.3M

Select item 982946915.

Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism

Song Ah Chae, Jun Seok Son, Jeanene Marie de Avila, Min Du, Mei-Jun Zhu

Am J Physiol Regul Integr Comp Physiol. 2022 Nov 1; 323(5): R728–R738. Published online 2022 Oct 3. doi: 10.1152/ajpregu.00128.2022

PMCID:: PMC9829469

Abstract Article

Select item 967369016.

Long‐Term Activation of Glucagon‐like peptide‐1 receptor by Dulaglutide Prevents Diabetic Heart Failure and Metabolic Remodeling in Type 2 Diabetes

Saiyang Xie, Min Zhang, Wenke Shi, Yun Xing, Yan Huang, Wen‐xi Fang, Shi‐qiang Liu, Meng‐Ya Chen, Tong Zhang, Si Chen, Xiaofeng Zeng, Shasha Wang, Wei Deng, Qizhu Tang

J Am Heart Assoc. 2022 Oct 4; 11(19): e026728. Published online 2022 Sep 29. doi: 10.1161/JAHA.122.026728

PMCID:: PMC9673690

Abstract Article PDF–20M

Select item 963795817.

Macrophage Sprouty4 deficiency diminishes sepsis-induced acute lung injury in mice

Rong Chen, Chen Cao, Huimin Liu, Wanli Jiang, Rui Pan, He He, Ke Ding, Qingtao Meng

Redox Biol. 2022 Dec; 58: 102513. Published online 2022 Oct 22. doi: 10.1016/j.redox.2022.102513

Correction in:: Redox Biol. 2023 Jun; 62: 102667.

PMCID:: PMC9637958

Abstract Article PDF–7.5M

Select item 958481518.

The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK

Chen-Song Zhang, Mengqi Li, Yu Wang, Xiaoyang Li, Yue Zong, Shating Long, Mingliang Zhang, Jin-Wei Feng, Xiaoyan Wei, Yan-Hui Liu, Baoding Zhang, Jianfeng Wu, Cixiong Zhang, Wenhua Lian, Teng Ma, Xiao Tian, Qi Qu, Yaxin Yu, Jinye Xiong, Dong-Tai Liu, Zhenhua Wu, Mingxia Zhu, Changchuan Xie, Yaying Wu, Zheni Xu, Chunyan Yang, Junjie Chen, Guohong Huang, Qingxia He, Xi Huang, Lei Zhang, Xiufeng Sun, Qingfeng Liu, Abdul Ghafoor, Fu Gui, Kaili Zheng, Wen Wang, Zhi-Chao Wang, Yong Yu, Qingliang Zhao, Shu-Yong Lin, Zhi-Xin Wang, Hai-Long Piao, Xianming Deng, Sheng-Cai Lin

Nat Metab. 2022; 4(10): 1369–1401. Published online 2022 Oct 10. doi: 10.1038/s42255-022-00640-7

PMCID:: PMC9584815

Abstract Article PDF–9.0M

Select item 946441619.

AMP-activated protein kinase α2 contributes to acute and chronic hyperuricemic nephropathy via renal urate deposition in a mouse model

Chen Yang, Hong-yong Su, Ning An, Hong-luan Wu, Xiao-yan Guo, Zhi-hang Li, Xiao-cui Chen, Shao-ping Zhu, Dan Wu, Hui-yuan Li, Qing-jun Pan, Dong Liang, Hua-feng Liu

Eur J Med Res. 2022; 27: 176. Published online 2022 Sep 10. doi: 10.1186/s40001-022-00800-1

PMCID:: PMC9464416

Abstract Article PDF–19M

Select item 941819220.

AMPK deficiency in smooth muscles causes persistent pulmonary hypertension of the new-born and premature death

Javier Moral-Sanz, Sophronia A. Lewis, Sandy MacMillan, Marco Meloni, Heather McClafferty, Benoit Viollet, Marc Foretz, Jorge del-Pozo, A. Mark Evans

Nat Commun. 2022; 13: 5034. Published online 2022 Aug 26. doi: 10.1038/s41467-022-32568-7

PMCID:: PMC9418192

Abstract Article PDF–8.8M

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