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Select item 113394111.

Limb reduction in an Esco2 cohesinopathy mouse model is mediated by p53-dependent apoptosis and vascular disruption

Arielle S. Strasser, Ana Silvia Gonzalez-Reiche, Xianxiao Zhou, Braulio Valdebenito-Maturana, Xiaoqian Ye, Bin Zhang, Meng Wu, Harm van Bakel, Ethylin Wang Jabs

Nat Commun. 2024; 15: 7154. Published online 2024 Aug 21. doi: 10.1038/s41467-024-51328-3

PMCID:: PMC11339411

Abstract Article PDF–9.4M

Select item 100932692.

Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell Proliferation and Photoreceptor Maintenance

Andrea Kuzelova, Naoko Dupacova, Barbora Antosova, Sweetu Susan Sunny, Zbynek Kozmik, Jr., Jan Paces, Arthur I. Skoultchi, Tomas Stopka, Zbynek Kozmik

Cells. 2023 Apr; 12(7): 1035. Published online 2023 Mar 28. doi: 10.3390/cells12071035

PMCID:: PMC10093269

Abstract Article PDF–21M

Select item 97118813.

Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation

Kensei Taguchi, Bertha C. Elias, Sho Sugahara, Snehal Sant, Benjamin S. Freedman, Sushrut S. Waikar, Ambra Pozzi, Roy Zent, Raymond C. Harris, Samir M. Parikh, Craig R. Brooks

J Clin Invest. 2022 Dec 1; 132(23): e158096. Published online 2022 Dec 1. doi: 10.1172/JCI158096

PMCID:: PMC9711881

Abstract Article PDF–21M

Select item 94094264.

Craniofacial Defects in Embryos with Homozygous Deletion of Eftud2 in Their Neural Crest Cells Are Not Rescued by Trp53 Deletion

Marie-Claude Beauchamp, Alexia Boucher, Yanchen Dong, Rachel Aber, Loydie A. Jerome-Majewska

Int J Mol Sci. 2022 Aug; 23(16): 9033. Published online 2022 Aug 12. doi: 10.3390/ijms23169033

PMCID:: PMC9409426

Abstract Article PDF–4.4M

Select item 92358755.

Snrpb is required in murine neural crest cells for proper splicing and craniofacial morphogenesis

Sabrina Shameen Alam, Shruti Kumar, Marie-Claude Beauchamp, Eric Bareke, Alexia Boucher, Nadine Nzirorera, Yanchen Dong, Reinnier Padilla, Si Jing Zhang, Jacek Majewski, Loydie A. Jerome-Majewska

Dis Model Mech. 2022 Jun 1; 15(6): dmm049544. Published online 2022 Jun 23. doi: 10.1242/dmm.049544

PMCID:: PMC9235875

Abstract Article

Select item 90908326.

Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression

Norihisa Bizen, Asim K. Bepari, Li Zhou, Manabu Abe, Kenji Sakimura, Katsuhiko Ono, Hirohide Takebayashi

Cell Death Differ. 2022 May; 29(5): 1028–1041. Published online 2022 Jan 1. doi: 10.1038/s41418-021-00915-8

PMCID:: PMC9090832

Abstract Article PDF–8.5M

Select item 87970317.

Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity

Chang Xie, Shaun R. Abrams, Vicente Herranz Pérez, Jose Manuel García Verdugo, Jeremy F. Reiter

Dev Cell. Author manuscript; available in PMC 2022 Dec 20.

Published in final edited form as: Dev Cell. 2021 Dec 20; 56(24): 3334–3348.e6. doi: 10.1016/j.devcel.2021.11.020

PMCID:: PMC8797031

Abstract Article PDF–2.2M

Select item 83191238.

A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies

Gerald C. Tiu, Craig H. Kerr, Craig M. Forester, Pallavi S. Krishnarao, Hannah D. Rosenblatt, Nitin Raj, Travis C. Lantz, Olena Zhulyn, Margot E. Bowen, Leila Shokat, Laura D. Attardi, Davide Ruggero, Maria Barna

Dev Cell. Author manuscript; available in PMC 2022 Jul 26.

Published in final edited form as: Dev Cell. 2021 Jul 26; 56(14): 2089–2102.e11. Published online 2021 Jul 8. doi: 10.1016/j.devcel.2021.06.013

PMCID:: PMC8319123

Abstract Article PDF–2.5M

Select item 81615249.

Mutation in Eftud2 causes craniofacial defects in mice via mis-splicing of Mdm2 and increased P53

Marie-Claude Beauchamp, Anissa Djedid, Eric Bareke, Fjodor Merkuri, Rachel Aber, Annie S Tam, Matthew A Lines, Kym M Boycott, Peter C Stirling, Jennifer L Fish, Jacek Majewski, Loydie A Jerome-Majewska

Hum Mol Genet. 2021 May 1; 30(9): 739–757. Published online 2021 Feb 18. doi: 10.1093/hmg/ddab051

PMCID:: PMC8161524

Abstract Article PDF–2.0M

Select item 802656310.

Robust p53 stabilization is dispensable for its activation and tumor suppressor function

Ning Kon, Michael Churchill, Huan Li, Siddhartha Mukherjee, James J. Manfredi, Wei Gu

Cancer Res. Author manuscript; available in PMC 2021 Aug 15.

Published in final edited form as: Cancer Res. 2021 Feb 15; 81(4): 935–944. Published online 2020 Dec 15. doi: 10.1158/0008-5472.CAN-20-1804

PMCID:: PMC8026563

Abstract Article PDF–1.5M

Select item 785567911.

Gestational Folate Deficiency Alters Embryonic Gene Expression and Cell Function

RS Seelan, P Mukhopadhyay, J Philipose, RM Greene, MM Pisano

Differentiation. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Differentiation. 2021 Jan-Feb; 117: 1–15. Published online 2020 Nov 27. doi: 10.1016/j.diff.2020.11.001

PMCID:: PMC7855679

Abstract Article PDF–2.7M

Select item 749052212.

Pak1ip1 Loss-of-Function Leads to Cell Cycle Arrest, Loss of Neural Crest Cells, and Craniofacial Abnormalities

Alexios A. Panoutsopoulos, Angelo Harlan De Crescenzo, Albert Lee, Amelia MacKenzie Lu, Adam P. Ross, Laura N. Borodinsky, Ralph Marcucio, Paul A. Trainor, Konstantinos S. Zarbalis

Front Cell Dev Biol. 2020; 8: 510063. Published online 2020 Sep 1. doi: 10.3389/fcell.2020.510063

PMCID:: PMC7490522

Abstract Article PDF–5.6M

Select item 748706513.

Mdm4 controls ureteric bud branching via regulation of p53 activity

Sylvia A. Hilliard, Yuwen Li, Angelina Dixon, Samir S. El-Dahr

Mech Dev. Author manuscript; available in PMC 2021 Sep 1.

Published in final edited form as: Mech Dev. 2020 Sep; 163: 103616. Published online 2020 May 25. doi: 10.1016/j.mod.2020.103616

PMCID:: PMC7487065

Abstract Article PDF–4.3M

Select item 692772314.

Inactivation of Mdm2 restores apoptosis proficiency of cooperativity mutant p53 in vivo

Boris Klimovich, Thorsten Stiewe, Oleg Timofeev

Cell Cycle. 2020; 19(1): 109–123. Published online 2019 Nov 21. doi: 10.1080/15384101.2019.1693748

PMCID:: PMC6927723

Abstract Article PDF–3.9M

Select item 667172415.

Neuronal Death Resulting from Targeted Disruption of the Snf2 Protein ATRX Is Mediated by p53

Claudia Seah, Michael A. Levy, Yan Jiang, Sulayman Mokhtarzada, Douglas R. Higgs, Richard J. Gibbons, Nathalie G. Bérubé

J Neurosci. 2008 Nov 19; 28(47): 12570–12580. doi: 10.1523/JNEUROSCI.4048-08.2008

PMCID:: PMC6671724

Abstract Article PDF–992K

Select item 657916316.

p53-Independent Cyclin G Expression in a Group of Mature Neurons and Its Enhanced Expression during Nerve Regeneration

Naonori Morita, Sumiko Kiryu, and Hiroshi Kiyama

J Neurosci. 1996 Oct 1; 16(19): 5961–5966. doi: 10.1523/JNEUROSCI.16-19-05961.1996

PMCID:: PMC6579163

Abstract Article PDF–1.3M

Select item 652711717.

Cyclin G1 and TASCC regulate kidney epithelial cell G₂-M arrest and fibrotic maladaptive repair

Guillaume Canaud, Craig R. Brooks, Seiji Kishi, Kensei Taguchi, Kenji Nishimura, Sato Magassa, Adam Scott, Li-Li Hsiao, Takaharu Ichimura, Fabiola Terzi, Li Yang, Joseph V. Bonventre

Sci Transl Med. Author manuscript; available in PMC 2020 Jan 23.

Published in final edited form as: Sci Transl Med. 2019 Jan 23; 11(476): eaav4754. doi: 10.1126/scitranslmed.aav4754