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Select item 110445051.

Dysregulation of innate immune signaling in animal models of spinal muscular atrophy

Eric L. Garcia, Rebecca E. Steiner, Amanda C. Raimer, Laura E. Herring, A. Gregory Matera, Ashlyn M. Spring

BMC Biol. 2024; 22: 94. Published online 2024 Apr 25. doi: 10.1186/s12915-024-01888-z

PMCID:: PMC11044505

Abstract Article PDF–4.0M

Select item 109730112.

The utility of Drosophila melanogaster as a fungal infection model

Chengetai D. Mpamhanga, Ilias Kounatidis

Front Immunol. 2024; 15: 1349027. Published online 2024 Mar 14. doi: 10.3389/fimmu.2024.1349027

PMCID:: PMC10973011

Abstract Article PDF–707K

Select item 108477253.

Bone morphogenetic protein signaling: the pathway and its regulation

Takuya Akiyama, Laurel A Raftery, Kristi A Wharton

Genetics. 2024 Feb; 226(2): iyad200. Published online 2023 Dec 20. doi: 10.1093/genetics/iyad200

PMCID:: PMC10847725

Abstract Article PDF–6.8M

Select item 107737984.

Recent trends in insect gut immunity

Shahidul Ahmed Khan, Maryam Ali Mohmmadie Kojour, Yeon Soo Han

Front Immunol. 2023; 14: 1272143. Published online 2023 Dec 18. doi: 10.3389/fimmu.2023.1272143

PMCID:: PMC10773798

Abstract Article PDF–7.2M

Select item 102809285.

Inhibition of the MEK/ERK pathway suppresses immune overactivation and mitigates TDP-43 toxicity in a Drosophila model of ALS

Wenkai Yue, Xue Deng, Zhao Wang, Mingsheng Jiang, Rirong Hu, Yongjia Duan, Qiangqiang Wang, Jihong Cui, Yanshan Fang

Immun Ageing. 2023; 20: 27. Published online 2023 Jun 20. doi: 10.1186/s12979-023-00354-8

PMCID:: PMC10280928

Abstract Article PDF–9.0M

Select item 101104026.

A Drosophila chemical screen reveals synergistic effect of MEK and DGKα inhibition in Ras-driven cancer

John E. La Marca, Robert W. Ely, Sarah T. Diepstraten, Peter Burke, Gemma L. Kelly, Patrick O. Humbert, Helena E. Richardson

Dis Model Mech. 2023 Mar 1; 16(3): dmm049769. Published online 2023 Apr 3. doi: 10.1242/dmm.049769

PMCID:: PMC10110402

Abstract Article

Select item 101057367.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 97513028.

Wun2-mediated integrin recycling promotes apoptotic cell clearance in Drosophila melanogaster

Ning Gao, Qian Zheng, Yanzhe Wang, Xiaowen Li, Zhi Li, Hui Xiao

Cell Death Differ. 2022 Dec; 29(12): 2545–2561. Published online 2022 Jul 15. doi: 10.1038/s41418-022-01039-3

PMCID:: PMC9751302

Abstract Article PDF–9.0M

Select item 96376349.

The sooner, the better: ROS, kinases and nutrients at the onset of the damage response in Drosophila

Florenci Serras

Front Cell Dev Biol. 2022; 10: 1047823. Published online 2022 Oct 24. doi: 10.3389/fcell.2022.1047823

PMCID:: PMC9637634

Abstract Article PDF–981K

Select item 945831810.

Drosophila as a toolkit to tackle cancer and its metabolism

Hui Jiang, Taku Kimura, Han Hai, Ryodai Yamamura, Masahiro Sonoshita

Front Oncol. 2022; 12: 982751. Published online 2022 Aug 25. doi: 10.3389/fonc.2022.982751

PMCID:: PMC9458318

Abstract Article PDF–1.2M

Select item 909466711.

IDH2-mediated regulation of the biogenesis of the oxidative phosphorylation system

Anjaneyulu Murari, Naga S. V. Goparaju, Shauna-Kay Rhooms, Kaniz F. B. Hossain, Felix G. Liang, Christian J. Garcia, Cindy Osei, Tong Liu, Hong Li, Richard N. Kitsis, Rajesh Patel, Edward Owusu-Ansah

Sci Adv. 2022 May; 8(19): eabl8716. Published online 2022 May 11. doi: 10.1126/sciadv.abl8716

PMCID:: PMC9094667

Abstract Article PDF–21M

Select item 885661912.

Physiological ROS controls Upd3-dependent modeling of ECM to support cardiac function in Drosophila

Jayati Gera, Prerna Budakoti, Meghna Suhag, Lolitika Mandal, Sudip Mandal

Sci Adv. 2022 Feb; 8(7): eabj4991. Published online 2022 Feb 18. doi: 10.1126/sciadv.abj4991

PMCID:: PMC8856619

Abstract Article PDF–16M

Select item 880564813.

Insect Gut Regeneration

Peng Zhang, Bruce A. Edgar

Cold Spring Harb Perspect Biol. 2022 Feb; 14(2): a040915. doi: 10.1101/cshperspect.a040915

PMCID:: PMC8805648

Abstract Article PDF–1.8M

Select item 859010214.

Drosophila p38 MAPK interacts with BAG‐3/starvin to regulate age‐dependent protein homeostasis

Sarah M. Ryan, Michael Almassey, Amelia M. Burch, Gia Ngo, Julia M. Martin, David Myers, Devin Compton, Shira Archie, Megan Cross, Lauren Naeger, Ashley Salzman, Alyssa Virola‐Iarussi, Scott A. Barbee, Nathan T. Mortimer, Subhabrata Sanyal, Alysia D. Vrailas‐Mortimer

Aging Cell. 2021 Nov; 20(11): e13481. Published online 2021 Oct 21. doi: 10.1111/acel.13481