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Select item 86644861.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 73824672.

Duplex DNA engagement and RPA oppositely regulate the DNA-unwinding rate of CMG helicase

Hazal B. Kose, Sherry Xie, George Cameron, Melania S. Strycharska, Hasan Yardimci

Nat Commun. 2020; 11: 3713. Published online 2020 Jul 24. doi: 10.1038/s41467-020-17443-7

PMCID:: PMC7382467

Abstract Article PDF–2.6M

Select item 69615783.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 65174134.

The mechanism of DNA unwinding by the eukaryotic replicative helicase

Daniel R. Burnham, Hazal B. Kose, Rebecca B. Hoyle, Hasan Yardimci

Nat Commun. 2019; 10: 2159. Published online 2019 May 14. doi: 10.1038/s41467-019-09896-2

PMCID:: PMC6517413

Abstract Article PDF–1.2M

Select item 63962935.

Activation of the MCM2-7 Helicase by Association with Cdc45 and GINS proteins

Ivar Ilves, Tatjana Petojevic, James J. Pesavento, Michael R. Botchan

Mol Cell. Author manuscript; available in PMC 2019 Mar 1.

Published in final edited form as: Mol Cell. 2010 Jan 29; 37(2): 247–258. doi: 10.1016/j.molcel.2009.12.030

PMCID:: PMC6396293

Abstract Article PDF–1007K

Select item 57078056.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 56890027.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 55863798.

DNA Replication Control During Drosophila Development: Insights into the Onset of S Phase, Replication Initiation, and Fork Progression

Brian L. Hua, Terry L. Orr-Weaver

Genetics. 2017 Sep; 207(1): 29–47. Published online 2017 Aug 31. doi: 10.1534/genetics.115.186627

PMCID:: PMC5586379

Abstract Article PDF–1.2M

Select item 55001409.

Neutral Competition for Drosophila Follicle and Cyst Stem Cell Niches Requires Vesicle Trafficking Genes

Matthew S. Cook, Coralie Cazin, Marc Amoyel, Shinya Yamamoto, Erika Bach, Todd Nystul

Genetics. 2017 Jul; 206(3): 1417–1428. Published online 2017 May 16. doi: 10.1534/genetics.117.201202

PMCID:: PMC5500140

Abstract Article PDF–2.3M

Select item 473800510.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

Select item 452833011.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832912.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 435936713.

DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome

Alessandro Costa, Ludovic Renault, Paolo Swuec, Tatjana Petojevic, James J Pesavento, Ivar Ilves, Kirsty MacLellan-Gibson, Roland A Fleck, Michael R Botchan, James M Berger

eLife. 2014; 3: e03273. Published online 2014 Aug 12. doi: 10.7554/eLife.03273

PMCID:: PMC4359367

Abstract Article PDF–3.2M

Select item 435288714.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 419936315.

Large-scale identification of chemically induced mutations in Drosophila melanogaster

Nele A. Haelterman, Lichun Jiang, Yumei Li, Vafa Bayat, Hector Sandoval, Berrak Ugur, Kai Li Tan, Ke Zhang, Danqing Bei, Bo Xiong, Wu-Lin Charng, Theodore Busby, Adeel Jawaid, Gabriela David, Manish Jaiswal, Koen J.T. Venken, Shinya Yamamoto, Rui Chen, Hugo J. Bellen

Genome Res. 2014 Oct; 24(10): 1707–1718. doi: 10.1101/gr.174615.114

PMCID:: PMC4199363

Abstract Article PDF–1.2M

Select item 418403316.

The structural basis for MCM2–7 helicase activation by GINS and Cdc45

Alessandro Costa, Ivar Ilves, Nele Tamberg, Tatjana Petojevic, Eva Nogales, Michael R Botchan, James M Berger

Nat Struct Mol Biol. Author manuscript; available in PMC 2014 Oct 3.

Published in final edited form as: Nat Struct Mol Biol. 2011 Apr; 18(4): 471–477. Published online 2011 Mar 6. doi: 10.1038/nsmb.2004

PMCID:: PMC4184033

Abstract Article PDF–1.2M

Select item 353067717.

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

Philippe Batut, Alexander Dobin, Charles Plessy, Piero Carninci, Thomas R. Gingeras

Genome Res. 2013 Jan; 23(1): 169–180. doi: 10.1101/gr.139618.112

PMCID:: PMC3530677

Abstract Article PDF–1.5M

Select item 346946718.

The Many Landscapes of Recombination in Drosophila melanogaster

Josep M. Comeron, Ramesh Ratnappan, Samuel Bailin

PLoS Genet. 2012 Oct; 8(10): e1002905. Published online 2012 Oct 11. doi: 10.1371/journal.pgen.1002905

PMCID:: PMC3469467

Abstract Article PDF–1.6M

Select item 342122419.

Checkpoint kinase 2 (Chk2) inhibits the activity of the Cdc45/MCM2-7/GINS (CMG) replicative helicase complex

Ivar Ilves, Nele Tamberg, Michael R. Botchan

Proc Natl Acad Sci U S A. 2012 Aug 14; 109(33): 13163–13170. Published online 2012 Aug 1. doi: 10.1073/pnas.1211525109

PMCID:: PMC3421224

Abstract Article PDF–1.4M

Select item 304044120.

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionary-conserved pain gene

G. Gregory Neely, Andreas Hess, Michael Costigan, Alex C. Keene, Spyros Goulas, Michiel Langeslag, Robert S Griffin, Inna Belfer, Feng Dai, Shad Smith, Luda Diatchenko, Vaijayanti Gupta, Cui-ping Xia, Sabina Amann, Silke Kreitz, Cornelia Heindl-Erdmann, Susanne Wolz, Cindy V. Ly, Suchir Arora, Rinku Sarangi, Debasis Dan, Maria Novatchkova, Mark Rosenzweig, Dustin Gibson, Darwin Truong, Daniel Schramek, Tamara Zoranovic, Shane J. F. Cronin, Belinda Angjeli, Kay Brune, Georg Dietzl, William Maixner, Arabella Meixner, Winston Thomas, J. Andrew Pospisilik, Mattias Alenius, Michaela Kress, Sai Subramaniam, Paul A. Garrity, Hugo J. Bellen, Clifford J. Woolf, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Nov 12.

Published in final edited form as: Cell. 2010 Nov 12; 143(4): 628–638. doi: 10.1016/j.cell.2010.09.047

PMCID:: PMC3040441

Abstract Article PDF–2.0M

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