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Select item 109359541.

Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila

Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale, Tiina S. Salminen

BMC Biol. 2024; 22: 60. Published online 2024 Mar 13. doi: 10.1186/s12915-024-01858-5

PMCID:: PMC10935954

Article PDF–2.4M

Select item 108162822.

The Lifespan of D. melanogaster Depends on the Function of the Gagr Gene, a Domesticated gag Gene of Drosophila LTR Retrotransposons

Yevgenia Balakireva, Maria Nikitina, Pavel Makhnovskii, Inna Kukushkina, Ilya Kuzmin, Alexander Kim, Lidia Nefedova

Insects. 2024 Jan; 15(1): 68. Published online 2024 Jan 17. doi: 10.3390/insects15010068

PMCID:: PMC10816282

Article PDF–4.1M

Select item 107737983.

Recent trends in insect gut immunity

Shahidul Ahmed Khan, Maryam Ali Mohmmadie Kojour, Yeon Soo Han

Front Immunol. 2023; 14: 1272143. Published online 2023 Dec 18. doi: 10.3389/fimmu.2023.1272143

PMCID:: PMC10773798

Article PDF–7.2M

Select item 107326904.

A Drosophila melanogaster model shows that fast growing Metarhizium species are the deadliest despite eliciting a strong immune response

Jonathan B. Wang, Hsiao-Ling Lu, Huiyu Sheng, Raymond J St. Leger

Virulence. 2023; 14(1): 2275493. Published online 2023 Nov 8. doi: 10.1080/21505594.2023.2275493

PMCID:: PMC10732690

Article PDF–4.7M

Select item 107325365.

An evolutionarily conserved serine protease network mediates melanization and Toll activation in Drosophila

Tisheng Shan, Yang Wang, Krishna Bhattarai, Haobo Jiang

Sci Adv. 2023 Dec 22; 9(51): eadk2756. Published online 2023 Dec 20. doi: 10.1126/sciadv.adk2756

PMCID:: PMC10732536

Article PDF–1.3M

Select item 100632186.

The Effect of Developmental Pleiotropy on the Evolution of Insect Immune Genes

Alissa M Williams, Thi Minh Ngo, Veronica E Figueroa, Ann T Tate

Genome Biol Evol. 2023 Mar; 15(3): evad044. Published online 2023 Mar 13. doi: 10.1093/gbe/evad044

PMCID:: PMC10063218

Article PDF–2.1M

Select item 96356447.

Enteric bacterial infection in Drosophila induces whole-body alterations in metabolic gene expression independently of the immune deficiency signaling pathway

Rujuta Deshpande, Byoungchun Lee, Savraj S Grewal

G3 (Bethesda) 2022 Nov; 12(11): jkac163. Published online 2022 Jul 4. doi: 10.1093/g3journal/jkac163

PMCID:: PMC9635644

Article PDF–2.2M

Select item 93364668.

Drosophila Innate Immunity Involves Multiple Signaling Pathways and Coordinated Communication Between Different Tissues

Shichao Yu, Fangzhou Luo, Yongyi Xu, Yan Zhang, Li Hua Jin

Front Immunol. 2022; 13: 905370. Published online 2022 Jul 7. doi: 10.3389/fimmu.2022.905370

PMCID:: PMC9336466

Article PDF–4.4M

Select item 89446669.

Injury-induced inflammatory signaling and hematopoiesis in Drosophila

Cory J. Evans, Ting Liu, Juliet R. Girard, Utpal Banerjee

Proc Natl Acad Sci U S A. 2022 Mar 22; 119(12): e2119109119. Published online 2022 Mar 14. doi: 10.1073/pnas.2119109119

PMCID:: PMC8944666

Article PDF–2.5M

Select item 866448610.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Article PDF–3.1M

Select item 761070311.

A SuperFamily-Wide Activity Atlas of Serine Hydrolases in Drosophila Melanogaster

Kundan Kumar, Amol Mhetre, Girish S. Ratnaparkhi, Siddhesh S. Kamat

Biochemistry. Author manuscript; available in PMC 2021 Oct 27.

Published in final edited form as: Biochemistry. 2021 Apr 27; 60(16): 1312–1324. Published online 2021 Apr 7. doi: 10.1021/acs.biochem.1c00171

PMCID:: PMC7610703

Article PDF–1.7M

Select item 745831212.

Anthrax toxin component, Protective Antigen, protects insects from bacterial infections

Saleem Alameh, Gloria Bartolo, Summer O’Brien, Elizabeth A. Henderson, Leandra O. Gonzalez, Stella Hartmann, Christopher P. Klimko, Jennifer L. Shoe, Christopher K. Cote, Laurence K. Grill, Anastasia Levitin, Mikhail Martchenko Shilman

PLoS Pathog. 2020 Aug; 16(8): e1008836. Published online 2020 Aug 31. doi: 10.1371/journal.ppat.1008836

PMCID:: PMC7458312

Article PDF–3.8M

Select item 696157813.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Article PDF–3.6M

Select item 657348014.

The Genome of Drosophila innubila Reveals Lineage-Specific Patterns of Selection in Immune Genes

Tom Hill, Boryana S Koseva, Robert L Unckless

Mol Biol Evol. 2019 Jul; 36(7): 1405–1417. Published online 2019 Mar 13. doi: 10.1093/molbev/msz059

PMCID:: PMC6573480

Article PDF–5.4M

Select item 635821415.

Building a platform for predicting functions of serine protease-related proteins in Drosophila melanogaster and other insects

Xiaolong Cao, Haobo Jiang

Insect Biochem Mol Biol. Author manuscript; available in PMC 2019 Dec 1.

Published in final edited form as: Insect Biochem Mol Biol. 2018 Dec; 103: 53–69. Published online 2018 Oct 24. doi: 10.1016/j.ibmb.2018.10.006

PMCID:: PMC6358214

Article PDF–6.9M

Select item 615693916.

Spatially restricted regulation of Spätzle/Toll signaling during cell competition

Lale Alpar, Cora Bergantiños, Laura A. Johnston

Dev Cell. Author manuscript; available in PMC 2019 Sep 24.

Published in final edited form as: Dev Cell. 2018 Sep 24; 46(6): 706–719.e5. Published online 2018 Aug 23. doi: 10.1016/j.devcel.2018.08.001

PMCID:: PMC6156939

Article PDF–2.8M

Select item 591533817.

Analysis of immune-related genes during Nora virus infection of Drosophila melanogaster using next generation sequencing

Wilfredo Lopez, Alexis M. Page, Darby J. Carlson, Brad L. Ericson, Matyas F. Cserhati, Chittibabu Guda, Kimberly A. Carlson

AIMS Microbiol. 2018; 4(1): 123–139. Published online 2018 Feb 27. doi: 10.3934/microbiol.2018.1.123

PMCID:: PMC5915338

Article PDF–680K

Select item 582402518.

Mass Spectrometry-Based Screening Platform Reveals Orco Interactome in Drosophila melanogaster

Kate E. Yu, Do-Hyoung Kim, Yong-In Kim, Walton D. Jones, J. Eugene Lee

Mol Cells. 2018 Feb 28; 41(2): 150–159. Published online 2018 Feb 12. doi: 10.14348/molcells.2018.2305

PMCID:: PMC5824025

Article PDF–1.2M

Select item 582397419.

The Circulating Protease Persephone Is an Immune Sensor for Microbial Proteolytic Activities Upstream of the Drosophila Toll Pathway

Najwa Issa, Nina Guillaumot, Emilie Lauret, Nicolas Matt, Christine Schaeffer-Reiss, Alain Van Dorsselaer, Jean-Marc Reichhart, Florian Veillard

Mol Cell. 2018 Feb 15; 69(4): 539–550.e6. doi: 10.1016/j.molcel.2018.01.029

PMCID:: PMC5823974

Article

Select item 574092720.

The Toll pathway underlies host sexual dimorphism in resistance to both Gram-negative and Gram-positive bacteria in mated Drosophila

David F. Duneau, Hannah C. Kondolf, Joo Hyun Im, Gerardo A. Ortiz, Christopher Chow, Michael A. Fox, Ana T. Eugénio, J. Revah, Nicolas Buchon, Brian P. Lazzaro

BMC Biol. 2017; 15: 124. Published online 2017 Dec 21. doi: 10.1186/s12915-017-0466-3