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Select item 110874731.

Regulation of Myc transcription by an enhancer cluster dedicated to pluripotency and early embryonic expression

Lin Li-Bao, Covadonga Díaz-Díaz, Morena Raiola, Rocío Sierra, Susana Temiño, Francisco J. Moya, Sandra Rodriguez-Perales, Elisa Santos, Giovanna Giovinazzo, Tore Bleckwehl, Álvaro Rada-Iglesias, Francois Spitz, Miguel Torres

Nat Commun. 2024; 15: 3931. Published online 2024 May 10. doi: 10.1038/s41467-024-48258-5

PMCID:: PMC11087473

Abstract Article PDF–6.8M

Select item 109464402.

Sall4 regulates posterior trunk mesoderm development by promoting mesodermal gene expression and repressing neural genes in the mesoderm

Matthew P. Pappas, Hiroko Kawakami, Dylan Corcoran, Katherine Q. Chen, Earl Parker Scott, Julia Wong, Micah D. Gearhart, Ryuichi Nishinakamura, Yasushi Nakagawa, Yasuhiko Kawakami

Development. 2024 Mar 1; 151(5): dev202649. Published online 2024 Mar 4. doi: 10.1242/dev.202649

PMCID:: PMC10946440

Abstract Article

Select item 109017373.

On the genetic basis of tail-loss evolution in humans and apes

Bo Xia, Weimin Zhang, Guisheng Zhao, Xinru Zhang, Jiangshan Bai, Ran Brosh, Aleksandra Wudzinska, Emily Huang, Hannah Ashe, Gwen Ellis, Maayan Pour, Yu Zhao, Camila Coelho, Yinan Zhu, Alexander Miller, Jeremy S. Dasen, Matthew T. Maurano, Sang Y. Kim, Jef D. Boeke, Itai Yanai

Nature. 2024; 626(8001): 1042–1048. Published online 2024 Feb 28. doi: 10.1038/s41586-024-07095-8

PMCID:: PMC10901737

Abstract Article PDF–5.7M

Select item 107582924.

Enhancer–promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness

Shreeta Chakraborty, Nina Kopitchinski, Zhenyu Zuo, Ariel Eraso, Parirokh Awasthi, Raj Chari, Apratim Mitra, Ian C. Tobias, Sakthi D. Moorthy, Ryan K. Dale, Jennifer A. Mitchell, Timothy J. Petros, Pedro P. Rocha

Nat Genet. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: Nat Genet. 2023 Feb; 55(2): 280–290. Published online 2023 Jan 30. doi: 10.1038/s41588-022-01295-6

PMCID:: PMC10758292

Abstract Article PDF–4.9M

Select item 105848995.

Conserved enhancers control notochord expression of vertebrate Brachyury

Cassie L. Kemmler, Jana Smolikova, Hannah R. Moran, Brandon J. Mannion, Dunja Knapp, Fabian Lim, Anna Czarkwiani, Viviana Hermosilla Aguayo, Vincent Rapp, Olivia E. Fitch, Seraina Bötschi, Licia Selleri, Emma Farley, Ingo Braasch, Maximina Yun, Axel Visel, Marco Osterwalder, Christian Mosimann, Zbynek Kozmik, Alexa Burger

Nat Commun. 2023; 14: 6594. Published online 2023 Oct 18. doi: 10.1038/s41467-023-42151-3

PMCID:: PMC10584899

Abstract Article PDF–6.1M

Select item 105314586.

The Germinal Origin of Salivary and Lacrimal Glands and the Contributions of Neural Crest Cell-Derived Epithelium to Tissue Regeneration

Hitomi Ono-Minagi, Tsutomu Nohno, Takashi Serizawa, Yu Usami, Takayoshi Sakai, Hideyuki Okano, Hideyo Ohuchi

Int J Mol Sci. 2023 Sep; 24(18): 13692. Published online 2023 Sep 5. doi: 10.3390/ijms241813692

PMCID:: PMC10531458

Abstract Article PDF–14M

Select item 105021537.

Time space and single-cell resolved tissue lineage trajectories and laterality of body plan at gastrulation

Ran Wang, Xianfa Yang, Jiehui Chen, Lin Zhang, Jonathan A. Griffiths, Guizhong Cui, Yingying Chen, Yun Qian, Guangdun Peng, Jinsong Li, Liantang Wang, John C. Marioni, Patrick P. L. Tam, Naihe Jing

Nat Commun. 2023; 14: 5675. Published online 2023 Sep 14. doi: 10.1038/s41467-023-41482-5

PMCID:: PMC10502153

Abstract Article PDF–8.1M

Select item 103570368.

TMEM132A regulates mouse hindgut morphogenesis and caudal development

Huiqing Zeng, Aimin Liu

Development. 2023 Jul 15; 150(14): dev201630. Published online 2023 Jul 13. doi: 10.1242/dev.201630

PMCID:: PMC10357036

Abstract Article

Select item 103359379.

Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis

Abhishek Sampath Kumar, Luyi Tian, Adriano Bolondi, Amèlia Aragonés Hernández, Robert Stickels, Helene Kretzmer, Evan Murray, Lars Wittler, Maria Walther, Gabriel Barakat, Leah Haut, Yechiel Elkabetz, Evan Z. Macosko, Léo Guignard, Fei Chen, Alexander Meissner

Nat Genet. 2023; 55(7): 1176–1185. Published online 2023 Jul 6. doi: 10.1038/s41588-023-01435-6

PMCID:: PMC10335937

Abstract Article PDF–25M

Select item 1026673610.

Yap controls notochord formation and neural tube patterning by integrating mechanotransduction with FoxA2 and Shh expression

Caiqi Cheng, Qian Cong, Yuchen Liu, Yizhong Hu, Guoyan Liang, Kevin Marc Manquiquis Dioneda, Yingzi Yang

Sci Adv. 2023 Jun; 9(24): eadf6927. Published online 2023 Jun 14. doi: 10.1126/sciadv.adf6927

PMCID:: PMC10266736

Abstract Article PDF–2.4M

Select item 1024753311.

Multicellular rosettes link mesenchymal-epithelial transition to radial intercalation in the mouse axial mesoderm

Marissa L. Gredler, Jennifer A. Zallen

Dev Cell. Author manuscript; available in PMC 2023 Jun 8.

Published in final edited form as: Dev Cell. 2023 Jun 5; 58(11): 933–950.e5. Published online 2023 Apr 19. doi: 10.1016/j.devcel.2023.03.018

PMCID:: PMC10247533

Abstract Article PDF–2.3M

Select item 1020311212.

Base editing-mediated one-step inactivation of the Dnmt gene family reveals critical roles of DNA methylation during mouse gastrulation

Qing Li, Jiansen Lu, Xidi Yin, Yunjian Chang, Chao Wang, Meng Yan, Li Feng, Yanbo Cheng, Yun Gao, Beiying Xu, Yao Zhang, Yingyi Wang, Guizhong Cui, Luang Xu, Yidi Sun, Rong Zeng, Yixue Li, Naihe Jing, Guo-Liang Xu, Ligang Wu, Fuchou Tang, Jinsong Li

Nat Commun. 2023; 14: 2922. Published online 2023 May 22. doi: 10.1038/s41467-023-38528-z

PMCID:: PMC10203112

Abstract Article PDF–11M

Select item 1017418913.

Diet-mediated constitutive induction of novel IL-4⁺ ILC2 cells maintains intestinal homeostasis in mice

Wanlin Cui, Yuji Nagano, Satoru Morita, Takeshi Tanoue, Hidehiro Yamane, Keiko Ishikawa, Toshiro Sato, Masato Kubo, Shohei Hori, Tadatsugu Taniguchi, Masanori Hatakeyama, Koji Atarashi, Kenya Honda

J Exp Med. 2023 Aug 7; 220(8): e20221773. Published online 2023 May 10. doi: 10.1084/jem.20221773

PMCID:: PMC10174189

Abstract Article PDF–5.3M

Select item 1007967714.

Intercellular exchange of Wnt ligands reduces cell population heterogeneity during embryogenesis

Yudai Hatakeyama, Nen Saito, Yusuke Mii, Ritsuko Takada, Takuma Shinozuka, Tatsuya Takemoto, Honda Naoki, Shinji Takada

Nat Commun. 2023; 14: 1924. Published online 2023 Apr 6. doi: 10.1038/s41467-023-37350-x

PMCID:: PMC10079677

Abstract Article PDF–12M

Select item 977181915.

Primate gastrulation and early organogenesis at single-cell resolution

Jinglei Zhai, Jing Guo, Haifeng Wan, Luqing Qi, Lizhong Liu, Zhenyu Xiao, Long Yan, Daniel A. Schmitz, Yanhong Xu, Dainan Yu, Xulun Wu, Wentao Zhao, Kunyuan Yu, Xiangxiang Jiang, Fan Guo, Jun Wu, Hongmei Wang

Nature. 2022; 612(7941): 732–738. Published online 2022 Dec 14. doi: 10.1038/s41586-022-05526-y

PMCID:: PMC9771819

Abstract Article PDF–19M

Select item 953683716.

Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor

Antigoni Gogolou, Celine Souilhol, Ilaria Granata, Filip J Wymeersch, Ichcha Manipur, Matthew Wind, Thomas JR Frith, Maria Guarini, Alessandro Bertero, Christoph Bock, Florian Halbritter, Minoru Takasato, Mario R Guarracino, Anestis Tsakiridis

eLife. 2022; 11: e74263. Published online 2022 Sep 26. doi: 10.7554/eLife.74263

PMCID:: PMC9536837

Abstract Article PDF–15M

Select item 953477217.

Embryo model completes gastrulation to neurulation and organogenesis

Gianluca Amadei, Charlotte E. Handford, Chengxiang Qiu, Joachim De Jonghe, Hannah Greenfeld, Martin Tran, Beth K. Martin, Dong-Yuan Chen, Alejandro Aguilera-Castrejon, Jacob H. Hanna, Michael B. Elowitz, Florian Hollfelder, Jay Shendure, David M. Glover, Magdalena Zernicka-Goetz

Nature. 2022; 610(7930): 143–153. Published online 2022 Aug 25. doi: 10.1038/s41586-022-05246-3

PMCID:: PMC9534772

Abstract Article PDF–29M

Select item 953441318.

The RNA helicase DDX6 controls early mouse embryogenesis by repressing aberrant inhibition of BMP signaling through miRNA-mediated gene silencing

Jessica Kim, Masafumi Muraoka, Hajime Okada, Atsushi Toyoda, Rieko Ajima, Yumiko Saga

PLoS Genet. 2022 Oct; 18(10): e1009967. Published online 2022 Oct 5. doi: 10.1371/journal.pgen.1009967

PMCID:: PMC9534413

Abstract Article PDF–3.8M

Select item 949956119.

Progesterone Receptor Modulates Extraembryonic Mesoderm and Cardiac Progenitor Specification during Mouse Gastrulation

Anna Maria Drozd, Luca Mariani, Xiaogang Guo, Victor Goitea, Niels Alvaro Menezes, Elisabetta Ferretti

Int J Mol Sci. 2022 Sep; 23(18): 10307. Published online 2022 Sep 7. doi: 10.3390/ijms231810307

PMCID:: PMC9499561

Abstract Article PDF–6.8M

Select item 948516120.

A stem cell roadmap of ribosome heterogeneity reveals a function for RPL10A in mesoderm production

Naomi R. Genuth, Zhen Shi, Koshi Kunimoto, Victoria Hung, Adele F. Xu, Craig H. Kerr, Gerald C. Tiu, Juan A. Oses-Prieto, Rachel E. A. Salomon-Shulman, Jeffrey D. Axelrod, Alma L. Burlingame, Kyle M. Loh, Maria Barna

Nat Commun. 2022; 13: 5491. Published online 2022 Sep 19. doi: 10.1038/s41467-022-33263-3