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Select item 111140441.

O-GlcNAc modification is essential for the regulation of autophagy in Drosophila melanogaster

Sujin Park, Yangsin Lee, Jin Won Pak, Hanbyeol Kim, Hyeonjin Choi, Jae-woo Kim, Jürgen Roth, Jin Won Cho

Cell Mol Life Sci. 2015 Aug; 72(16): 3173–3183. Published online 2015 Apr 4. doi: 10.1007/s00018-015-1889-z

PMCID:: PMC11114044

Abstract Article PDF–3.6M

Select item 110445052.

Dysregulation of innate immune signaling in animal models of spinal muscular atrophy

Eric L. Garcia, Rebecca E. Steiner, Amanda C. Raimer, Laura E. Herring, A. Gregory Matera, Ashlyn M. Spring

BMC Biol. 2024; 22: 94. Published online 2024 Apr 25. doi: 10.1186/s12915-024-01888-z

PMCID:: PMC11044505

Abstract Article PDF–4.0M

Select item 110040193.

Elevated α-synuclein levels inhibit mitophagic flux

Inge Kinnart, Liselot Manders, Thibaut Heyninck, Dorien Imberechts, Roman Praschberger, Nils Schoovaerts, Catherine Verfaillie, Patrik Verstreken, Wim Vandenberghe

NPJ Parkinsons Dis. 2024; 10: 80. Published online 2024 Apr 9. doi: 10.1038/s41531-024-00696-0

PMCID:: PMC11004019

Abstract Article PDF–6.7M

Select item 109904844.

Expanding the Drosophila toolkit for dual control of gene expression

Jonathan Zirin, Barbara Jusiak, Raphael Lopes, Benjamin Ewen-Campen, Justin A Bosch, Alexandria Risbeck, Corey Forman, Christians Villalta, Yanhui Hu, Norbert Perrimon

eLife. 2024; 12: RP94073. Published online 2024 Apr 3. doi: 10.7554/eLife.94073

PMCID:: PMC10990484

Abstract Article PDF–6.0M

Select item 109359545.

Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila

Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale, Tiina S. Salminen

BMC Biol. 2024; 22: 60. Published online 2024 Mar 13. doi: 10.1186/s12915-024-01858-5

PMCID:: PMC10935954

Abstract Article PDF–2.4M

Select item 108867416.

Understanding Developmental Cell Death Using Drosophila as a Model System

Ruchi Umargamwala, Jantina Manning, Loretta Dorstyn, Donna Denton, Sharad Kumar

Cells. 2024 Feb; 13(4): 347. Published online 2024 Feb 16. doi: 10.3390/cells13040347

PMCID:: PMC10886741

Abstract Article PDF–1.6M

Select item 108693627.

The Drosophila ZNRF1/2 homologue, detour, interacts with HOPS complex and regulates autophagy

Shannon Nicolson, Jantina A. Manning, Yoon Lim, Xin Jiang, Erica Kolze, Sonia Dayan, Ruchi Umargamwala, Tianqi Xu, Jarrod J. Sandow, Andrew I. Webb, Sharad Kumar, Donna Denton

Commun Biol. 2024; 7: 183. Published online 2024 Feb 15. doi: 10.1038/s42003-024-05834-1

PMCID:: PMC10869362

Abstract Article PDF–6.1M

Select item 107809548.

TDP-43 impairs sleep in Drosophila through Ataxin-2–dependent metabolic disturbance

Alexandra E. Perlegos, Jaclyn Durkin, Samuel J. Belfer, Anyara Rodriguez, Oksana Shcherbakova, Kristen Park, Jenny Luong, Nancy M. Bonini, Matthew S. Kayser

Sci Adv. 2024 Jan 12; 10(2): eadj4457. Published online 2024 Jan 10. doi: 10.1126/sciadv.adj4457

PMCID:: PMC10780954

Abstract Article PDF–2.1M

Select item 107433849.

The Drosophila NPY-like system protects against chronic stress–induced learning deficit by preventing the disruption of autophagic flux

Tianli Chen, Mengyu Zhang, Zhaowen Ding, Jiao Hu, Jie Yang, Lei He, Jia Jia, Jingjing Yang, Junfei Yang, Xiaoxu Song, Peng Chen, Zongzhao Zhai, Jing Huang, Yirong Wang, Hongtao Qin

Proc Natl Acad Sci U S A. 2023 Dec 19; 120(51): e2307632120. Published online 2023 Dec 11. doi: 10.1073/pnas.2307632120

PMCID:: PMC10743384

Abstract Article PDF–1.3M

Select item 1073335610.

Microbes control Drosophila germline stem cell increase and egg maturation through hormonal pathways

Ritsuko Suyama, Nicolas Cetraro, Joanne Y. Yew, Toshie Kai

Commun Biol. 2023; 6: 1287. Published online 2023 Dec 20. doi: 10.1038/s42003-023-05660-x

PMCID:: PMC10733356

Abstract Article PDF–3.7M

Select item 1069850811.

A multi‐layered network model identifies Akt1 as a common modulator of neurodegeneration

Dokyun Na, Do‐Hwan Lim, Jae‐Sang Hong, Hyang‐Mi Lee, Daeahn Cho, Myeong‐Sang Yu, Bilal Shaker, Jun Ren, Bomi Lee, Jae Gwang Song, Yuna Oh, Kyungeun Lee, Kwang‐Seok Oh, Mi Young Lee, Min‐Seok Choi, Han Saem Choi, Yang‐Hee Kim, Jennifer M Bui, Kangseok Lee, Hyung Wook Kim, Young Sik Lee, Jörg Gsponer

Mol Syst Biol. 2023 Dec; 19(12): e11801. Published online 2023 Nov 20. doi: 10.15252/msb.202311801

PMCID:: PMC10698508

Abstract Article PDF–7.0M

Select item 1069741612.

Systematic assessment of transcriptomic and metabolic reprogramming by blue light exposure coupled with aging

Jia Huang, Fan Zhou, Huanchan Zhou, Xiaoqi Zheng, Zhengyi Huo, Meng Yang, Zihe Xu, Runzhou Liu, Luoluo Wang, Xiaoyun Wang

PNAS Nexus. 2023 Dec; 2(12): pgad390. Published online 2023 Dec 5. doi: 10.1093/pnasnexus/pgad390

PMCID:: PMC10697416

Abstract Article PDF–1.3M

Select item 1067219013.

Research Progress on the Regulation of Autophagy and Apoptosis in Insects by Sterol Hormone 20-Hydroxyecdysone

Luobin Lin, Huaqin Li, Qinzhou Zheng, Jiaxuan Hu, Wenmei Wu

Insects. 2023 Nov; 14(11): 871. Published online 2023 Nov 12. doi: 10.3390/insects14110871

PMCID:: PMC10672190

Abstract Article PDF–976K

Select item 1066557414.

Protein modification regulated autophagy in Bombyx mori and Drosophila melanogaster

Wenmei Wu, Luobin Lin, Yuntao Zhao, Huaqin Li, Rongxin Zhang

Front Physiol. 2023; 14: 1281555. Published online 2023 Nov 9. doi: 10.3389/fphys.2023.1281555

PMCID:: PMC10665574

Abstract Article PDF–1.1M

Select item 1062955915.

Cyclin-G-associated kinase GAK/dAux regulates autophagy initiation via ULK1/Atg1 in glia

Shiping Zhang, Shuanglong Yi, Linfang Wang, Shuhua Li, Honglei Wang, Li Song, Jiayao Ou, Min Zhang, Ruiqi Wang, Mengxiao Wang, Yuchen Zheng, Kai Yang, Tong Liu, Margaret S. Ho

Proc Natl Acad Sci U S A. 2023 Jul 18; 120(29): e2301002120. Published online 2023 Jul 10. doi: 10.1073/pnas.2301002120

PMCID:: PMC10629559

Abstract Article PDF–6.9M

Select item 1054919216.

Polyploidy-associated autophagy promotes larval tracheal histolysis at Drosophila metamorphosis

Beatriz Pino-Jiménez, Panagiotis Giannios, Jordi Casanova

Autophagy. 2023; 19(11): 2972–2981. Published online 2023 Jul 9. doi: 10.1080/15548627.2023.2231828

PMCID:: PMC10549192

Abstract Article PDF–2.8M

Select item 1052345117.

Iditarod, a Drosophila homolog of the Irisin precursor FNDC5, is critical for exercise performance and cardiac autophagy

Tyler Cobb, Irene Hwang, Michael Soukar, Sim Namkoong, Uhn-Soo Cho, Maryam Safdar, Myungjin Kim, Robert J. Wessells, Jun Hee Lee

Proc Natl Acad Sci U S A. 2023 Sep 26; 120(39): e2220556120. Published online 2023 Sep 18. doi: 10.1073/pnas.2220556120

PMCID:: PMC10523451

Abstract Article PDF–3.1M

Select item 1051329518.

A monocarboxylate transporter rescues frontotemporal dementia and Alzheimer’s disease models

Dongwei Xu, Alec Vincent, Andrés González-Gutiérrez, Benjamin Aleyakpo, Sharifah Anoar, Ashling Giblin, Magda L. Atilano, Mirjam Adams, Dunxin Shen, Annora Thoeng, Elli Tsintzas, Marie Maeland, Adrian M. Isaacs, Jimena Sierralta, Teresa Niccoli

PLoS Genet. 2023 Sep; 19(9): e1010893. Published online 2023 Sep 21. doi: 10.1371/journal.pgen.1010893