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Select item 115004181.

Formaldehyde regulates S-adenosylmethionine biosynthesis and one-carbon metabolism

Vanha N. Pham, Kevin J. Bruemmer, Joel D. W. Toh, Eva J. Ge, Logan Tenney, Carl C. Ward, Felix A. Dingler, Christopher L. Millington, Carlos A. Garcia-Prieto, Mia C. Pulos-Holmes, Nicholas T. Ingolia, Lucas B. Pontel, Manel Esteller, Ketan J. Patel, Daniel K. Nomura, Christopher J. Chang

Science. Author manuscript; available in PMC 2024 Oct 24.

Published in final edited form as: Science. 2023 Nov 3; 382(6670): eabp9201. Published online 2023 Nov 3. doi: 10.1126/science.abp9201

PMCID:: PMC11500418

Article PDF–2.2M

Select item 113644582.

S-Nitrosoglutathione Reductase (GSNOR) Deficiency Results in Secondary Hypogonadism

Thomas A. Masterson, Himanshu Arora, Shathiyah Kulandavelu, Rona S. Carroll, Ursula B. Kaiser, Sakir H. Gultekin, Joshua M. Hare, Ranjith Ramasamy

J Sex Med. Author manuscript; available in PMC 2024 Aug 30.

Published in final edited form as: J Sex Med. 2018 May; 15(5): 654–661. Published online 2018 Mar 30. doi: 10.1016/j.jsxm.2018.03.002

PMCID:: PMC11364458

Article PDF–1.1M

Select item 112531613.

S-nitrosoglutathione reductase alleviates morphine analgesic tolerance by restricting PKCα S-nitrosation

Ling-Yan Su, Lijin Jiao, Qianjin Liu, Xinhua Qiao, Ting Xie, Zhiyu Ma, Min Xu, Mao-Sen Ye, Lu-Xiu Yang, Chang Chen, Yong-Gang Yao

Redox Biol. 2024 Sep; 75: 103239. Published online 2024 Jun 14. doi: 10.1016/j.redox.2024.103239

PMCID:: PMC11253161

Article PDF–4.4M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Article PDF–4.8M

Select item 108974545.

S-nitrosothiol homeostasis maintained by ADH5 facilitates STING-dependent host defense against pathogens

Mutian Jia, Li Chai, Jie Wang, Mengge Wang, Danhui Qin, Hui Song, Yue Fu, Chunyuan Zhao, Chengjiang Gao, Jihui Jia, Wei Zhao

Nat Commun. 2024; 15: 1750. Published online 2024 Feb 26. doi: 10.1038/s41467-024-46212-z

PMCID:: PMC10897454

Article PDF–5.0M

Select item 107483936.

Efficacies of S-nitrosoglutathione (GSNO) and GSNO reductase inhibitor in SARS-CoV-2 spike protein induced acute lung disease in mice

Judong Kim, Fei Qiao, Avtar K. Singh, Jeseong Won, Inderjit Singh

Front Pharmacol. 2023; 14: 1304697. Published online 2023 Dec 8. doi: 10.3389/fphar.2023.1304697

PMCID:: PMC10748393

Article PDF–6.0M

Select item 105157027.

S-Nitrosoglutathione Reductase Dysfunction Contributes to Obesity-Associated Hepatic Insulin Resistance via Regulating Autophagy

Qingwen Qian, Zeyuan Zhang, Allyson Orwig, Songhai Chen, Wen-Xing Ding, Yanji Xu, Ryan C. Kunz, Nicholas R.L. Lind, Jonathan S. Stamler, Ling Yang

Diabetes. 2018 Feb; 67(2): 193–207. Published online 2017 Oct 26. doi: 10.2337/db17-0223

PMCID:: PMC10515702

Article PDF–3.2M

Select item 104192368.

Class III Alcohol Dehydrogenase Plays a Key Role in the Onset of Alcohol-Related/-Associated Liver Disease as an S-Nitrosoglutathione Reductase in Mice

Takeshi Haseba, Motoyo Maruyama, Toshio Akimoto, Isao Yamamoto, Midori Katsuyama, Takahisa Okuda

Int J Mol Sci. 2023 Aug; 24(15): 12102. Published online 2023 Jul 28. doi: 10.3390/ijms241512102

PMCID:: PMC10419236

Article PDF–4.2M

Select item 92045089.

Protein S-nitrosylation regulates proteostasis and viability of hematopoietic stem cell during regeneration

Weiwei Yi, Yuying Zhang, Bo Liu, Yuanyuan Zhou, Dandan Liao, Xinhua Qiao, Dan Gao, Ting Xie, Qin Yao, Yao Zhang, Yugang Qiu, Gang Huang, Zhiyang Chen, Chang Chen, Zhenyu Ju

Cell Rep. Author manuscript; available in PMC 2022 Jun 17.

Published in final edited form as: Cell Rep. 2021 Mar 30; 34(13): 108922. doi: 10.1016/j.celrep.2021.108922

PMCID:: PMC9204508

Article PDF–1.0M

Select item 907505910.

S‐Nitrosoglutathione Reductase Deficiency Causes Aberrant Placental S‐Nitrosylation and Preeclampsia

Shathiyah Kulandavelu, Raul A. Dulce, Christopher I. Murray, Michael A. Bellio, Julia Fritsch, Rosemeire Kanashiro‐Takeuchi, Himanshu Arora, Ellena Paulino, Daniel Soetkamp, Wayne Balkan, Jenny E. Van Eyk, Joshua M. Hare

J Am Heart Assoc. 2022 Mar 1; 11(5): e024008. Published online 2022 Feb 22. doi: 10.1161/JAHA.121.024008

PMCID:: PMC9075059

Article PDF–3.7M

Select item 864099611.

ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue

Sara C. Sebag, Zeyuan Zhang, Qingwen Qian, Mark Li, Zhiyong Zhu, Mikako Harata, Wenxian Li, Leonid V. Zingman, Limin Liu, Vitor A. Lira, Matthew J. Potthoff, Alexander Bartelt, Ling Yang

Cell Rep. Author manuscript; available in PMC 2021 Dec 3.

Published in final edited form as: Cell Rep. 2021 Nov 16; 37(7): 110003. doi: 10.1016/j.celrep.2021.110003

PMCID:: PMC8640996

Article PDF–2.4M

Select item 857743812.

GSNOR facilitates antiviral innate immunity by restricting TBK1 cysteine S-nitrosation

Qianjin Liu, Tianle Gu, Ling-Yan Su, Lijin Jiao, Xinhua Qiao, Min Xu, Ting Xie, Lu-Xiu Yang, Dandan Yu, Ling Xu, Chang Chen, Yong-Gang Yao

Redox Biol. 2021 Nov; 47: 102172. Published online 2021 Oct 18. doi: 10.1016/j.redox.2021.102172

PMCID:: PMC8577438

Article PDF–8.1M

Select item 832011813.

Bronchopulmonary Dysplasia and Pulmonary Hypertension. The Role of Smooth Muscle adh5

Thomas M. Raffay, Koby Bonilla-Fernandez, Anjum Jafri, Ramadan B. Sopi, Laura A. Smith, Feifei Cui, Maureen O’Reilly, Rongli Zhang, Craig A. Hodges, Peter M. MacFarlane, Gail Deutsch, Richard J. Martin, Benjamin Gaston

Am J Respir Cell Mol Biol. 2021 Jul; 65(1): 70–80. Published online 2021 Mar 30. doi: 10.1165/rcmb.2020-0289OC

PMCID:: PMC8320118

Article PDF–900K

Select item 798782314.

GSNOR and ALDH2 alleviate traumatic spinal cord injury

Mushfiquddin Khan, Fei Qiao, S.M. Touhidul Islam, Tajinder S. Dhammu, Pavan Kumar, Jeseong Won, Avtar K. Singh, Inderjit Singh

Brain Res. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Brain Res. 2021 May 1; 1758: 147335. Published online 2021 Feb 2. doi: 10.1016/j.brainres.2021.147335

PMCID:: PMC7987823

Article PDF–932K

Select item 793877015.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Article PDF–2.0M

Select item 784913416.

Etomoxir regulates the differentiation of male germ cells by specifically reducing H3K27ac level

Yushan Xu, Jue Xie

BMC Dev Biol. 2021; 21: 5. Published online 2021 Feb 1. doi: 10.1186/s12861-020-00237-x

PMCID:: PMC7849134

Article PDF–4.8M

Select item 775886117.

Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans

Felix A. Dingler, Meng Wang, Anfeng Mu, Christopher L. Millington, Nina Oberbeck, Sam Watcham, Lucas B. Pontel, Ashley N. Kamimae-Lanning, Frederic Langevin, Camille Nadler, Rebecca L. Cordell, Paul S. Monks, Rui Yu, Nicola K. Wilson, Asuka Hira, Kenichi Yoshida, Minako Mori, Yusuke Okamoto, Yusuke Okuno, Hideki Muramatsu, Yuichi Shiraishi, Masayuki Kobayashi, Toshinori Moriguchi, Tomoo Osumi, Motohiro Kato, Satoru Miyano, Etsuro Ito, Seiji Kojima, Hiromasa Yabe, Miharu Yabe, Keitaro Matsuo, Seishi Ogawa, Berthold Göttgens, Michael R.G. Hodskinson, Minoru Takata, Ketan J. Patel

Mol Cell. 2020 Dec 17; 80(6): 996–1012.e9. doi: 10.1016/j.molcel.2020.10.012

PMCID:: PMC7758861

Article

Select item 688562418.

AKR1A1 is a novel mammalian S-nitroso-glutathione reductase

Colin T. Stomberski, Puneet Anand, Nicholas M. Venetos, Alfred Hausladen, Hua-Lin Zhou, Richard T. Premont, Jonathan S. Stamler

J Biol Chem. 2019 Nov 29; 294(48): 18285–18293. Published online 2019 Oct 23. doi: 10.1074/jbc.RA119.011067

PMCID:: PMC6885624

Article PDF–1.3M

Select item 659661119.

Increased GSNOR Expression during Aging Impairs Cognitive Function and Decreases S-Nitrosation of CaMKIIα

Yuying Zhang, Kaiyuan Wu, Wenting Su, Deng-Feng Zhang, Ping Wang, Xinhua Qiao, Qin Yao, Zengqiang Yuan, Yong-Gang Yao, Guanghui Liu, Chen Zhang, Limin Liu, Chang Chen

J Neurosci. 2017 Oct 4; 37(40): 9741–9758. doi: 10.1523/JNEUROSCI.0681-17.2017

PMCID:: PMC6596611

Article PDF–3.2M

Select item 649488420.

nNOS/GSNOR interaction contributes to skeletal muscle differentiation and homeostasis

Costanza Montagna, Salvatore Rizza, Claudia Cirotti, Emiliano Maiani, Maurizio Muscaritoli, Antonio Musarò, Maria Teresa Carrí, Elisabetta Ferraro, Francesco Cecconi, Giuseppe Filomeni

Cell Death Dis. 2019 May; 10(5): 354. Published online 2019 May 1. doi: 10.1038/s41419-019-1584-3

PMCID:: PMC6494884

Article PDF–3.1M

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