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Select item 113237871.

Astrocytic lipid metabolism determines susceptibility to diet-induced obesity

Luis Varela, Jae Geun Kim, Pablo Fernández-Tussy, Binod Aryal, Zhong Wu Liu, Carlos Fernández-Hernando, Tamas L. Horvath

Sci Adv. 2021 Dec; 7(50): eabj2814. Published online 2021 Dec 10. doi: 10.1126/sciadv.abj2814

PMCID:: PMC11323787

Abstract Article PDF–11M

Select item 111157012.

Reconstruction of gene association network reveals a transmembrane protein required for adipogenesis and targeted by PPARγ

Juliane G. Bogner-Strauss, Andreas Prokesch, Fatima Sanchez-Cabo, Dietmar Rieder, Hubert Hackl, Kalina Duszka, Anne Krogsdam, Barbara Di Camillo, Evelyn Walenta, Ariane Klatzer, Achim Lass, Montserrat Pinent, Wing-Cheong Wong, Frank Eisenhaber, Zlatko Trajanoski

Cell Mol Life Sci. 2010 Dec; 67(23): 4049–4064. Published online 2010 Jun 15. doi: 10.1007/s00018-010-0424-5

PMCID:: PMC11115701

Abstract Article PDF–1.1M

Select item 111152503.

Molecular regulation of PPARγ/RXRα signaling by the novel cofactor ZFP407

Alyssa Charrier, Jeremiah Ockunzzi, Leighanne Main, Siddharth V. Ghanta, David A. Buchner

PLoS One. 2024; 19(5): e0294003. Published online 2024 May 23. doi: 10.1371/journal.pone.0294003

PMCID:: PMC11115250

Abstract Article PDF–2.3M

Select item 111139554.

Transcription factor Snail is a novel regulator of adipocyte differentiation via inhibiting the expression of peroxisome proliferator-activated receptor γ

Yong-ho Lee, Soo Hyun Kim, Yoo Jeong Lee, Eun Seok Kang, Byung-Wan Lee, Bong Soo Cha, Jae Woo Kim, Dae Hyun Song, Hyun Chul Lee

Cell Mol Life Sci. 2013 Oct; 70(20): 3959–3971. Published online 2013 May 21. doi: 10.1007/s00018-013-1363-8

PMCID:: PMC11113955

Abstract Article PDF–1.7M

Select item 111103505.

BRD4 promotes gouty arthritis through MDM2-mediated PPARγ degradation and pyroptosis

Xiaoxia Xu, Hongbin Qiu

Mol Med. 2024; 30: 67. Published online 2024 May 21. doi: 10.1186/s10020-024-00831-w

PMCID:: PMC11110350

Abstract Article PDF–15M

Select item 110220786.

Exercise-induced BDNF promotes PPARδ-dependent reprogramming of lipid metabolism in skeletal muscle during exercise recovery

Wing Suen Chan, Chun Fai Ng, Brian Pak Shing Pang, Miaojia Hang, Margaret Chui Ling Tse, Elsie Chit Yu Iu, Xin Ci Ooi, Xiuying Yang, Jason K. Kim, Chi Wai Lee, Chi Bun Chan

Sci Signal. Author manuscript; available in PMC 2024 Apr 17.

Published in final edited form as: Sci Signal. 2024 Mar 19; 17(828): eadh2783. Published online 2024 Mar 19. doi: 10.1126/scisignal.adh2783

PMCID:: PMC11022078

Abstract Article PDF–2.7M

Select item 110206837.

SIRT3 regulates cardiolipin biosynthesis in pressure overload-induced cardiac remodeling by PPARγ-mediated mechanism

Ling-Xin Liu, Xue-Hui Zheng, Jing-Han Hai, Chun-Mei Zhang, Yun Ti, Tong-Shuai Chen, Pei-Li Bu

PLoS One. 2024; 19(4): e0301990. Published online 2024 Apr 16. doi: 10.1371/journal.pone.0301990

PMCID:: PMC11020683

Abstract Article PDF–3.7M

Select item 109176608.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 109017399.

A single-cell time-lapse of mouse prenatal development from gastrula to birth

Chengxiang Qiu, Beth K. Martin, Ian C. Welsh, Riza M. Daza, Truc-Mai Le, Xingfan Huang, Eva K. Nichols, Megan L. Taylor, Olivia Fulton, Diana R. O’Day, Anne Roshella Gomes, Saskia Ilcisin, Sanjay Srivatsan, Xinxian Deng, Christine M. Disteche, William Stafford Noble, Nobuhiko Hamazaki, Cecilia B. Moens, David Kimelman, Junyue Cao, Alexander F. Schier, Malte Spielmann, Stephen A. Murray, Cole Trapnell, Jay Shendure

Nature. 2024; 626(8001): 1084–1093. Published online 2024 Feb 14. doi: 10.1038/s41586-024-07069-w

PMCID:: PMC10901739

Abstract Article PDF–63M

Select item 1079997410.

PPARα and PPARγ are expressed in midbrain dopamine neurons and modulate dopamine- and cannabinoid-mediated behavior in mice

Briana Hempel, Madeline Crissman, Sruti Pari, Benjamin Klein, Guo-Hua Bi, Hannah Alton, Zheng-Xiong Xi

Mol Psychiatry. 2023; 28(10): 4203–4214. Published online 2023 Jul 21. doi: 10.1038/s41380-023-02182-0

PMCID:: PMC10799974

Abstract Article PDF–5.1M

Select item 1079224111.

Platelet-derived growth factor receptor beta is required for embryonic specification and confinement of the adult white adipose lineage

Abigail M. Benvie, Derek Lee, Yuwei Jiang, Daniel C. Berry

iScience. 2024 Jan 19; 27(1): 108682. Published online 2023 Dec 12. doi: 10.1016/j.isci.2023.108682

PMCID:: PMC10792241

Abstract Article PDF–7.6M

Select item 1078854012.

Testicular ACE regulates sperm metabolism and fertilization through the transcription factor PPARγ

Tomohiro Shibata, Shabir A. Bhat, DuoYao Cao, Suguru Saito, Ellen A. Bernstein, Erika Nishi, Juliet D. Medenilla, Erica T. Wang, Jessica L. Chan, Margareta D. Pisarska, Warren G. Tourtellotte, Jorge F. Giani, Kenneth E. Bernstein, Zakir Khan

J Biol Chem. 2024 Jan; 300(1): 105486. Published online 2023 Nov 20. doi: 10.1016/j.jbc.2023.105486

PMCID:: PMC10788540

Abstract Article PDF–2.0M

Select item 1077436213.

miR-195b is required for proper cellular homeostasis in the elderly

Maria del Mar Muñoz-Gallardo, Carlos Garcia-Padilla, Cristina Vicente-Garcia, Jaime Carvajal, Amelia Arenega, Diego Franco

Sci Rep. 2024; 14: 810. Published online 2024 Jan 8. doi: 10.1038/s41598-024-51256-8

PMCID:: PMC10774362

Abstract Article PDF–3.7M

Select item 1077110714.

KLF2/PPARγ axis contributes to trauma‐induced heterotopic ossification by regulating mitochondrial dysfunction

Ziyang Sun, Hang Liu, Yuehao Hu, Gang Luo, Zhengqiang Yuan, Weixuan Liu, Bing Tu, Hongjiang Ruan, Juehong Li, Cunyi Fan

Cell Prolif. 2024 Jan; 57(1): e13521. Published online 2023 Jun 21. doi: 10.1111/cpr.13521

PMCID:: PMC10771107

Abstract Article PDF–13M

Select item 1075142915.

Stimulator of interferon genes promotes diabetic sarcopenia by targeting peroxisome proliferator activated receptors γ degradation and inhibiting fatty acid oxidation

Sen‐bo Yan, Huan Liang, Peng Zhan, Hui Zheng, Qin‐xiao Zhao, Zi‐jie Zheng, Hui‐xia Lu, Guo‐kai Shang, Xiao‐ping Ji

J Cachexia Sarcopenia Muscle. 2023 Dec; 14(6): 2623–2641. Published online 2023 Sep 21. doi: 10.1002/jcsm.13336

PMCID:: PMC10751429

Abstract Article PDF–9.7M

Select item 1072118616.

Supraclavicular brown adipocytes originate from Tbx1⁺ myoprogenitors

Zan Huang, Chenxin Gu, Zengdi Zhang, Rini Arianti, Aneesh Swaminathan, Kevin Tran, Alex Battist, Endre Kristóf, Hai-Bin Ruan

PLoS Biol. 2023 Dec; 21(12): e3002413. Published online 2023 Dec 4. doi: 10.1371/journal.pbio.3002413

PMCID:: PMC10721186

Abstract Article PDF–3.7M

Select item 1064065017.

FKBP5 activates mitophagy by ablating PPAR-γ to shape a benign remyelination environment

Xingzong Sun, Menghan Qian, Hongliang Li, Lei Wang, Yunjie Zhao, Min Yin, Lili Dai, Hongkun Bao

Cell Death Dis. 2023 Nov; 14(11): 736. Published online 2023 Nov 11. doi: 10.1038/s41419-023-06260-7

PMCID:: PMC10640650

Abstract Article PDF–18M

Select item 1061776818.

A PPARγ/long noncoding RNA axis regulates adipose thermoneutral remodeling in mice

Zhengyi Zhang, Ya Cui, Vivien Su, Dan Wang, Marcus J. Tol, Lijing Cheng, Xiaohui Wu, Jason Kim, Prashant Rajbhandari, Sicheng Zhang, Wei Li, Peter Tontonoz, Claudio J. Villanueva, Tamer Sallam

J Clin Invest. 2023 Nov 1; 133(21): e170072. Published online 2023 Nov 1. doi: 10.1172/JCI170072

PMCID:: PMC10617768

Abstract Article PDF–3.3M

Select item 1061711919.

Swimming exercise ameliorates insulin resistance and nonalcoholic fatty liver by negatively regulating PPARγ transcriptional network in mice fed high fat diet

Yong Zhang, Jie Xu, Di Zhou, Tingting Ye, Puqing Zhou, Zuofeng Liu, Xinyuan Liu, Zinan Wang, Tianmiao Hua, Zhenghao Zhang, Qingyan Sun

Mol Med. 2023; 29: 150. Published online 2023 Oct 31. doi: 10.1186/s10020-023-00740-4

PMCID:: PMC10617119

Abstract Article PDF–4.3M

Select item 1059167220.

Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury

Natalia A. Veniaminova, Yunlong Y. Jia, Adrien M. Hartigan, Thomas J. Huyge, Shih-Ying Tsai, Marina Grachtchouk, Seitaro Nakagawa, Andrzej A. Dlugosz, Scott X. Atwood, Sunny Y. Wong

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Sep 26; 42(9): 113121. Published online 2023 Sep 19. doi: 10.1016/j.celrep.2023.113121

PMCID:: PMC10591672

Abstract Article PDF–3.4M

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