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Items: 1 to 20 of 61

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome
Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh
Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5
PMCID:
PMC10208958
AbstractArticlePDF–7.0M
3.
Glucose 6-P Dehydrogenase Overexpression Improves Aging-Induced Endothelial Dysfunction in Aorta from Mice: Role of Arginase II
Eva Serna, Maria D Mauricio, Teresa San-Miguel, Sol Guerra-Ojeda, David Verdú, Alicia Valls, Coralie Arc-Chagnaud, Adrián De la Rosa, José Viña
Int J Mol Sci. 2023 Feb; 24(4): 3622. Published online 2023 Feb 11. doi: 10.3390/ijms24043622
PMCID:
PMC9961129
AbstractArticlePDF–2.8M
4.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
5.
G6PD Deficiency Is Crucial for Insulin Signaling Activation in Skeletal Muscle
Aiwen Jiang, Hongyun Guo, Xiaoyu Jiang, Jingli Tao, Wangjun Wu, Honglin Liu
Int J Mol Sci. 2022 Jul; 23(13): 7425. Published online 2022 Jul 4. doi: 10.3390/ijms23137425
PMCID:
PMC9267066
AbstractArticlePDF–5.5M
6.
G6pd-Deficient Mice Are Protected From Experimental Cerebral Malaria and Liver Injury by Suppressing Proinflammatory Response in the Early Stage of Plasmodium berghei Infection
Haoan Yi, Weiyang Jiang, Fang Yang, Fan Li, Yirong Li, Wenjing Zhu, Qing Li, Syed Hassam Fakhar, Yaming Cao, Lan Luo, Wen Zhang, Yongshu He
Front Immunol. 2021; 12: 719189. Published online 2021 Aug 11. doi: 10.3389/fimmu.2021.719189
PMCID:
PMC8386684
AbstractArticlePDF–16M
7.
Glucose-6-phosphate dehydrogenase deficiency contributes to metabolic abnormality and pulmonary hypertension
Mathews Valuparampil Varghese, Joel James, Olga Rafikova, Ruslan Rafikov
Am J Physiol Lung Cell Mol Physiol. 2021 Apr 1; 320(4): L508–L521. Published online 2021 Jan 27. doi: 10.1152/ajplung.00165.2020
PMCID:
PMC8238156
AbstractArticle
8.
Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma
Yassene Mohammed, Sarah A. Michaud, Helena Pětrošová, Juncong Yang, Milan Ganguly, David Schibli, Ann M. Flenniken, Lauryl M. J. Nutter, Hibret A. Adissu, K. C. Kent Lloyd, Colin McKerlie, Christoph H. Borchers
NPJ Syst Biol Appl. 2021; 7: 25. Published online 2021 May 28. doi: 10.1038/s41540-021-00184-8
PMCID:
PMC8163790
AbstractArticlePDF–6.9M
9.
G6PD activity contributes to the regulation of histone acetylation and gene expression in smooth muscle cells and to the pathogenesis of vascular diseases
Vidhi Dhagia, Atsushi Kitagawa, Christina Jacob, Connie Zheng, Angelo D’Alessandro, John G. Edwards, Petra Rocic, Rakhee Gupte, Sachin A. Gupte
Am J Physiol Heart Circ Physiol. 2021 Mar 1; 320(3): H999–H1016. Published online 2021 Jan 8. doi: 10.1152/ajpheart.00488.2020
PMCID:
PMC7988761
AbstractArticle
10.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
11.
NF-κB inducing kinase maintains T cell metabolic fitness in antitumor immunity
Meidi Gu, Xiaofei Zhou, Jee Hyung Sohn, Lele Zhu, Zuliang Jie, Jin-Young Yang, Xiaofeng Zheng, Xiaoping Xie, Jie Yang, Yaoyao Shi, Hans D Brightbill, Jae Bum Kim, Jing Wang, Xuhong Cheng, Shao-Cong Sun
Nat Immunol. Author manuscript; available in PMC 2021 Jul 4.
Published in final edited form as: Nat Immunol. 2021 Feb; 22(2): 193–204. Published online 2021 Jan 4. doi: 10.1038/s41590-020-00829-6
Correction in:
Nat Immunol. 2021 Feb 11
PMCID:
PMC7855506
AbstractArticlePDF–3.2M
12.
Glucose-6-phosphate dehydrogenase increases Ca2+ currents by interacting with Cav1.2 and reducing intrinsic inactivation of the L-type calcium channel
Rakhee Gupte, Vidhi Dhagia, Petra Rocic, Rikuo Ochi, Sachin A. Gupte
Am J Physiol Heart Circ Physiol. 2020 Jul 1; 319(1): H144–H158. Published online 2020 May 22. doi: 10.1152/ajpheart.00727.2019
PMCID:
PMC7474437
AbstractArticle
13.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
14.
Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation
Sachindra Raj Joshi, Atsushi Kitagawa, Christina Jacob, Ryota Hashimoto, Vidhi Dhagia, Amrit Ramesh, Connie Zheng, Hui Zhang, Allan Jordan, Ian Waddell, Jane Leopold, Cheng-Jun Hu, Ivan F. McMurtry, Angelo D’Alessandro, Kurt R. Stenmark, Sachin A. Gupte
Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1; 318(4): L773–L786. Published online 2020 Mar 11. doi: 10.1152/ajplung.00001.2020
PMCID:
PMC7191486
AbstractArticle
15.
Pluripotent hematopoietic stem cells augment α-adrenergic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary hypertension
Ryota Hashimoto, Gregg M. Lanier, Vidhi Dhagia, Sachindra R. Joshi, Allan Jordan, Ian Waddell, Rubin Tuder, Kurt R. Stenmark, Michael S. Wolin, Ivan F. McMurtry, Sachin A. Gupte
Am J Physiol Lung Cell Mol Physiol. 2020 Feb 1; 318(2): L386–L401. Published online 2020 Jan 8. doi: 10.1152/ajplung.00327.2019
PMCID:
PMC7052680
AbstractArticle
16.
Neuroprotection by Transgenic Expression of Glucose-6-Phosphate Dehydrogenase in Dopaminergic Nigrostriatal Neurons of Mice
Rebeca Mejías, Javier Villadiego, C. Oscar Pintado, Pablo J. Vime, Lin Gao, Juan J. Toledo-Aral, Miriam Echevarría, José López-Barneo
J Neurosci. 2006 Apr 26; 26(17): 4500–4508. doi: 10.1523/JNEUROSCI.0122-06.2006
PMCID:
PMC6674068
AbstractArticlePDF–1.0M
17.
Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma
Abigail G Zieman, Brian G Poll, Jingqun Ma, Pierre A Coulombe
Hum Mol Genet. 2019 Jul 1; 28(13): 2255–2270. Published online 2019 Mar 20. doi: 10.1093/hmg/ddz050
PMCID:
PMC6602407
AbstractArticlePDF–3.5M
18.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
19.
LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow
Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher
J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214
PMCID:
PMC6262777
AbstractArticle
20.
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells
Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch
Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262
PMCID:
PMC6244183
AbstractArticlePDF–753K

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