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Select item 114082501.

Proteomic analysis of the developing mammalian brain links PCDH19 to the Wnt/β-catenin signalling pathway

Rebekah de Nys, Alison Gardner, Clare van Eyk, Stefka Mincheva-Tasheva, Paul Thomas, Rudrarup Bhattacharjee, Lachlan Jolly, Isabel Martinez-Garay, Ian W. J. Fox, Karthik Shantharam Kamath, Raman Kumar, Jozef Gecz

Mol Psychiatry. 2024; 29(7): 2199–2210. Published online 2024 Mar 7. doi: 10.1038/s41380-024-02482-z

PMCID:: PMC11408250

Abstract Article PDF–2.7M

Select item 113716552.

Neuronal network activity and connectivity are impaired in a conditional knockout mouse model with PCDH19 mosaic expression

Giorgia Giansante, Sara Mazzoleni, Antonio G. Zippo, Luisa Ponzoni, Anna Ghilardi, Greta Maiellano, Elly Lewerissa, Eline van Hugte, Nael Nadif Kasri, Maura Francolini, Mariaelvina Sala, Luca Murru, Silvia Bassani, Maria Passafaro

Mol Psychiatry. 2024; 29(6): 1710–1725. Published online 2023 Mar 30. doi: 10.1038/s41380-023-02022-1

PMCID:: PMC11371655

Abstract Article PDF–5.4M

Select item 106417453.

Pcdh19 mediates olfactory sensory neuron coalescence during postnatal stages and regeneration

Andrew P. Martinez, Alexander C. Chung, Suihong Huang, Adam J. Bisogni, Yingxin Lin, Yue Cao, Eric O. Williams, Jin Y. Kim, Jean Y.H. Yang, David M. Lin

iScience. 2023 Nov 17; 26(11): 108220. Published online 2023 Oct 16. doi: 10.1016/j.isci.2023.108220

PMCID:: PMC10641745

Abstract Article PDF–5.8M

Select item 102089584.

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh

Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5

PMCID:: PMC10208958

Abstract Article PDF–7.0M

Select item 98731985.

Female-specific synaptic dysfunction and cognitive impairment in a mouse model of PCDH19 disorder

Naosuke Hoshina, Erin M. Johnson-Venkatesh, Miyuki Hoshina, Hisashi Umemori

Science. Author manuscript; available in PMC 2023 Jan 24.

Published in final edited form as: Science. 2021 Apr 16; 372(6539): eaaz3893. doi: 10.1126/science.aaz3893

PMCID:: PMC9873198

Abstract Article PDF–2.9M

Select item 96420316.

Modifying PCDH19 levels affects cortical interneuron migration

Anna Pancho, Manuela D. Mitsogiannis, Tania Aerts, Marco Dalla Vecchia, Lena K. Ebert, Lieve Geenen, Lut Noterdaeme, Ria Vanlaer, Anne Stulens, Paco Hulpiau, Katrien Staes, Frans Van Roy, Peter Dedecker, Bernhard Schermer, Eve Seuntjens

Front Neurosci. 2022; 16: 887478. Published online 2022 Oct 25. doi: 10.3389/fnins.2022.887478

PMCID:: PMC9642031

Abstract Article PDF–5.9M

Select item 92221067.

Perturbation of Cortical Excitability in a Conditional Model of PCDH19 Disorder

Didi Lamers, Silvia Landi, Roberta Mezzena, Laura Baroncelli, Vinoshene Pillai, Federica Cruciani, Sara Migliarini, Sara Mazzoleni, Massimo Pasqualetti, Maria Passafaro, Silvia Bassani, Gian Michele Ratto

Cells. 2022 Jun; 11(12): 1939. Published online 2022 Jun 16. doi: 10.3390/cells11121939

PMCID:: PMC9222106

Abstract Article PDF–15M

Select item 83626848.

Cellular and Behavioral Characterization of Pcdh19 Mutant Mice: subtle Molecular Changes, Increased Exploratory Behavior and an Impact of Social Environment

Natalia Galindo-Riera, Sylvia Adriana Newbold, Monika Sledziowska, Cristina Llinares-Benadero, Jessica Griffiths, Erik Mire, Isabel Martinez-Garay

eNeuro. 2021 Jul-Aug; 8(4): ENEURO.0510-20.2021. Prepublished online 2021 Jul 16. Published online 2021 Aug 10. doi: 10.1523/ENEURO.0510-20.2021

PMCID:: PMC8362684

Abstract Article PDF–6.5M

Select item 80604959.

Cis-Repression of Foxq1 Expression Affects Foxf2-Mediated Gene Expression in Palate Development

Jingyue Xu, Han Liu, Yu Lan, Rulang Jiang

Front Cell Dev Biol. 2021; 9: 665109. Published online 2021 Apr 8. doi: 10.3389/fcell.2021.665109

PMCID:: PMC8060495

Abstract Article PDF–4.3M

Select item 772221810.

Characterization of seizure susceptibility in Pcdh19 mice

Jennifer Rakotomamonjy, Niki P. Sabetfakhri, Sean L. McDermott, Alicia Guemez-Gamboa

Epilepsia. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: Epilepsia. 2020 Oct; 61(10): 2313–2320. Published online 2020 Sep 18. doi: 10.1111/epi.16675

PMCID:: PMC7722218

Abstract Article PDF–1.2M

Select item 708820611.

Genome-wide Identification of Foxf2 Target Genes in Palate Development

J. Xu, H. Liu, Y. Lan, J.S. Park, R. Jiang

J Dent Res. 2020 Apr; 99(4): 463–471. Published online 2020 Feb 10. doi: 10.1177/0022034520904018

PMCID:: PMC7088206

Abstract Article PDF–2.0M

Select item 686496912.

Autism-like behaviors in male mice with a Pcdh19 deletion

Jisoo Lim, Jiin Ryu, Shinwon Kang, Hyun Jong Noh, Chul Hoon Kim

Mol Brain. 2019; 12: 95. Published online 2019 Nov 20. doi: 10.1186/s13041-019-0519-3

PMCID:: PMC6864969

Abstract Article PDF–937K

Select item 671839313.

TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex

Xiaohui Lv, Si-Qiang Ren, Xin-Jun Zhang, Zhongfu Shen, Tanay Ghosh, Anjin Xianyu, Peng Gao, Zhizhong Li, Susan Lin, Yang Yu, Qiangqiang Zhang, Matthias Groszer, Song-Hai Shi

Nat Commun. 2019; 10: 3946. Published online 2019 Sep 2. doi: 10.1038/s41467-019-11854-x

PMCID:: PMC6718393

Abstract Article PDF–6.8M

Select item 551764514.

Loss of X-linked Protocadherin-19 differentially affects the behavior of heterozygous female and hemizygous male mice

Shuichi Hayashi, Yoko Inoue, Satoko Hattori, Mari Kaneko, Go Shioi, Tsuyoshi Miyakawa, Masatoshi Takeichi

Sci Rep. 2017; 7: 5801. Published online 2017 Jul 19. doi: 10.1038/s41598-017-06374-x

PMCID:: PMC5517645

Abstract Article PDF–4.6M

Select item 544875015.

A dual-strategy expression screen for candidate connectivity labels in the developing thalamus

Olivia Bibollet-Bahena, Tatsuya Okafuji, Karsten Hokamp, Guy Tear, Kevin J. Mitchell

PLoS One. 2017; 12(5): e0177977. Published online 2017 May 30. doi: 10.1371/journal.pone.0177977

PMCID:: PMC5448750

Abstract Article PDF–113M

Select item 532227416.

A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling

M Fujitani, S Zhang, R Fujiki, Y Fujihara, T Yamashita

Mol Psychiatry. 2017 Mar; 22(3): 364–374. Published online 2016 Jul 5. doi: 10.1038/mp.2016.106

PMCID:: PMC5322274

Abstract Article PDF–773K

Select item 509485117.

MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders

Adam J Harrington, Aram Raissi, Kacey Rajkovich, Stefano Berto, Jaswinder Kumar, Gemma Molinaro, Jonathan Raduazzo, Yuhong Guo, Kris Loerwald, Genevieve Konopka, Kimberly M Huber, Christopher W Cowan

eLife. 2016; 5: e20059. Published online 2016 Oct 25. doi: 10.7554/eLife.20059

PMCID:: PMC5094851

Abstract Article PDF–4.6M

Select item 488621418.

Pcdh19 Loss-of-Function Increases Neuronal Migration In Vitro but is Dispensable for Brain Development in Mice

Daniel T. Pederick, Claire C. Homan, Emily J. Jaehne, Sandra G. Piltz, Bryan P. Haines, Bernhard T. Baune, Lachlan A. Jolly, James N. Hughes, Jozef Gecz, Paul Q. Thomas

Sci Rep. 2016; 6: 26765. Published online 2016 May 31. doi: 10.1038/srep26765

PMCID:: PMC4886214

Abstract Article PDF–1.4M

Select item 431955919.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 361324720.

Gata3 Is a Critical Regulator of Cochlear Wiring

Jessica M. Appler, Cindy C. Lu, Noah R. Druckenbrod, Wei-Ming Yu, Edmund J. Koundakjian, Lisa V. Goodrich

J Neurosci. 2013 Feb 20; 33(8): 3679–3691. doi: 10.1523/JNEUROSCI.4703-12.2013

PMCID:: PMC3613247

Abstract Article PDF–4.4M

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