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Select item 110093901.

Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer

Jie Fu, Jianhua Ling, Ching-Fei Li, Chi-Lin Tsai, Wenjuan Yin, Junwei Hou, Ping Chen, Yu Cao, Ya’an Kang, Yichen Sun, Xianghou Xia, Zhou Jiang, Kenei Furukawa, Yu Lu, Min Wu, Qian Huang, Jun Yao, David H. Hawke, Bih-Fang Pan, Jun Zhao, Jiaxing Huang, Huamin Wang, E. I. Mustapha Bahassi, Peter J. Stambrook, Peng Huang, Jason B. Fleming, Anirban Maitra, John A. Tainer, Mien-Chie Hung, Chunru Lin, Paul J. Chiao

Nat Commun. 2024; 15: 3149. Published online 2024 Apr 11. doi: 10.1038/s41467-024-47242-3

PMCID:: PMC11009390

Abstract Article PDF–8.5M

Select item 103078522.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 88913013.

Nardilysin in adipocytes regulates UCP1 expression and body temperature homeostasis

Sayaka Saijo, Mikiko Ohno, Hirotaka Iwasaki, Shintaro Matsuda, Kiyoto Nishi, Yoshinori Hiraoka, Natsuki Ide, Takeshi Kimura, Eiichiro Nishi

Sci Rep. 2022; 12: 3449. Published online 2022 Mar 2. doi: 10.1038/s41598-022-07379-x

PMCID:: PMC8891301

Abstract Article PDF–2.4M

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 59311275.

Nardilysin controls intestinal tumorigenesis through HDAC1/p53–dependent transcriptional regulation

Keitaro Kanda, Jiro Sakamoto, Yoshihide Matsumoto, Kozo Ikuta, Norihiro Goto, Yusuke Morita, Mikiko Ohno, Kiyoto Nishi, Koji Eto, Yuto Kimura, Yuki Nakanishi, Kanako Ikegami, Takaaki Yoshikawa, Akihisa Fukuda, Kenji Kawada, Yoshiharu Sakai, Akihiro Ito, Minoru Yoshida, Takeshi Kimura, Tsutomu Chiba, Eiichiro Nishi, Hiroshi Seno

JCI Insight. 2018 Apr 19; 3(8): e91316. Published online 2018 Apr 19. doi: 10.1172/jci.insight.91316

PMCID:: PMC5931127

Abstract Article PDF–11M

Select item 58681816.

CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice

Jin Li, Su-Ping Deng, Gang Wei, Peng Yu

Database (Oxford) 2018; 2018: bay012. Published online 2018 Mar 23. doi: 10.1093/database/bay012

PMCID:: PMC5868181

Abstract Article PDF–653K

Select item 56659177.

Genome-wide profiling of nardilysin target genes reveals its role in epigenetic regulation and cell cycle progression

Yusuke Morita, Mikiko Ohno, Kiyoto Nishi, Yoshinori Hiraoka, Sayaka Saijo, Shintaro Matsuda, Toru Kita, Takeshi Kimura, Eiichiro Nishi

Sci Rep. 2017; 7: 14801. Published online 2017 Nov 1. doi: 10.1038/s41598-017-14942-4

PMCID:: PMC5665917

Abstract Article PDF–2.2M

Select item 53223848.

Nardilysin regulates inflammation, metaplasia, and tumors in murine stomach

Yuto Kimura, Kozo Ikuta, Takeshi Kimura, Tsutomu Chiba, Hiroko Oshima, Masanobu Oshima, Eiichiro Nishi, Hiroshi Seno

Sci Rep. 2017; 7: 43052. Published online 2017 Feb 23. doi: 10.1038/srep43052

PMCID:: PMC5322384

Abstract Article PDF–2.2M

Select item 46861369.

Systematic Identification of Factors for Provirus Silencing in Embryonic Stem Cells

Bin Xia Yang, Chadi A. EL Farran, Hong Chao Guo, Tao Yu, Hai Tong Fang, Hao Fei Wang, Sharon Schlesinger, Yu Fen Samantha Seah, Germaine Yen Lin Goh, Suat Peng Neo, Yinghui Li, Matthew C. Lorincz, Vinay Tergaonkar, Tit-Meng Lim, Lingyi Chen, Jayantha Gunaratne, James J. Collins, Stephen P. Goff, George Q. Daley, Hu Li, Frederic A. Bard, Yuin-Han Loh

Cell. Author manuscript; available in PMC 2015 Dec 21.

Published in final edited form as: Cell. 2015 Sep 24; 163(1): 230–245. Published online 2015 Sep 10. doi: 10.1016/j.cell.2015.08.037

PMCID:: PMC4686136

Abstract Article PDF–1.2M

Select item 402981010.

Deletion of Nardilysin Prevents the Development of Steatohepatitis and Liver Fibrotic Changes

Shoko Ishizu-Higashi, Hiroshi Seno, Eiichiro Nishi, Yoshihide Matsumoto, Kozo Ikuta, Motoyuki Tsuda, Yoshito Kimura, Yutaka Takada, Yuto Kimura, Yuki Nakanishi, Keitaro Kanda, Hideyuki Komekado, Tsutomu Chiba

PLoS One. 2014; 9(5): e98017. Published online 2014 May 21. doi: 10.1371/journal.pone.0098017

PMCID:: PMC4029810

Abstract Article PDF–2.1M

Select item 392601011.

Critical roles of nardilysin in the maintenance of body temperature homoeostasis

Yoshinori Hiraoka, Tatsuhiko Matsuoka, Mikiko Ohno, Kazuhiro Nakamura, Sayaka Saijo, Shigenobu Matsumura, Kiyoto Nishi, Jiro Sakamoto, Po-Min Chen, Kazuo Inoue, Tohru Fushiki, Toru Kita, Takeshi Kimura, Eiichiro Nishi

Nat Commun. 2014 Feb 4; 5: 3224. Published online 2014 Feb 4. doi: 10.1038/ncomms4224

PMCID:: PMC3926010

Abstract Article PDF–2.1M

Select item 375379912.

Genomic Strategy Identifies a Missense Mutation in WD-Repeat Domain 65 (WDR65) in an Individual with Van der Woude Syndrome

Nicholas K. Rorick, Akira Kinoshita, Jason Weirather, Myriam Peyrard-Janvid, Renata L. L. Ferreira de Lima, Martine Dunnwald, Alan L. Shanske, Danilo Moretti-Ferreira, Hannele Koillinen, Juha Kere, Maria A. Mansilla, Jeffrey C. Murray, Steve L. Goudy, Brian C. Schutte

Am J Med Genet A. Author manuscript; available in PMC 2013 Aug 27.

Published in final edited form as: Am J Med Genet A. 2011 Jun; 0(6): 1314–1321. Published online 2011 May 13. doi: 10.1002/ajmg.a.33980

PMCID:: PMC3753799

Abstract Article PDF–742K

Select item 332304313.

Identification and Characterization of Nardilysin as a Novel Dimethyl H3K4-binding Protein Involved in Transcriptional Regulation

Jing Li, Mingyue Chu, Shanshan Wang, Doug Chan, Shankang Qi, Meng Wu, Zhongliang Zhou, Jiwen Li, Eiichiro Nishi, Jun Qin, Jiemin Wong

J Biol Chem. 2012 Mar 23; 287(13): 10089–10098. Published online 2012 Jan 30. doi: 10.1074/jbc.M111.313965

PMCID:: PMC3323043

Abstract Article PDF–1.6M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 277884415.

A mitochondrial protein compendium elucidates complex I disease biology

David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha

Cell. Author manuscript; available in PMC 2009 Nov 18.

Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016

PMCID:: PMC2778844

Abstract Article PDF–1.2M

Select item 255627016.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

Select item 141356817.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086