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Select item 111482821.

TRPC absence induces pro-inflammatory macrophage polarization to promote obesity and exacerbate colorectal cancer

Yanting Lin, Rui Gao, Dongquan Jing, Yiming Liu, Huijuan Da, Lutz Birnbaumer, Yong Yang, Xinghua Gao, Zhenhua Gao, Qiuhua Cao

Front Pharmacol. 2024; 15: 1392328. Published online 2024 May 21. doi: 10.3389/fphar.2024.1392328

PMCID:: PMC11148282

Abstract Article PDF–5.1M

Select item 111156292.

Functional interaction between TRPC1 channel and connexin-43 protein: a novel pathway underlying S1P action on skeletal myogenesis

Elisabetta Meacci, Francesca Bini, Chiara Sassoli, Maria Martinesi, Roberta Squecco, Flaminia Chellini, Sandra Zecchi-Orlandini, Fabio Francini, Lucia Formigli

Cell Mol Life Sci. 2010 Dec; 67(24): 4269–4285. Published online 2010 Jul 8. doi: 10.1007/s00018-010-0442-3

PMCID:: PMC11115629

Abstract Article PDF–1.3M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 106826444.

Loss of Ca²⁺ entry via Orai–TRPC1 induces ER stress, initiating immune activation in macrophages

Viviane Nascimento Da Conceicao, Yuyang Sun, Emily K. Zboril, Jorge J. De la Chapa, Brij B. Singh

J Cell Sci. 2020 Mar 1; 133(5): jcs237610. Published online 2019 Dec 18. doi: 10.1242/jcs.237610

PMCID:: PMC10682644

Abstract Article

Select item 97683285.

Deletion of classical transient receptor potential 1, 3 and 6 alters pulmonary vasoconstriction in chronic hypoxia-induced pulmonary hypertension in mice

Kathrin Malkmus, Monika Brosien, Fenja Knoepp, Lisa Schaffelhofer, Friedrich Grimminger, Christoph Rummel, Thomas Gudermann, Alexander Dietrich, Lutz Birnbaumer, Norbert Weissmann, Simone Kraut

Front Physiol. 2022; 13: 1080875. Published online 2022 Dec 7. doi: 10.3389/fphys.2022.1080875

PMCID:: PMC9768328

Abstract Article PDF–2.4M

Select item 97188416.

TRPC channels blockade abolishes endotoxemic cardiac dysfunction by hampering intracellular inflammation and Ca²⁺ leakage

Na Tang, Wen Tian, Guang-Yuan Ma, Xiong Xiao, Lei Zhou, Ze-Zhi Li, Xiao-Xiao Liu, Chong-Yao Li, Ke-Han Wu, Wenjuan Liu, Xue-Ying Wang, Yuan-Yuan Gao, Xin Yang, Jianzhao Qi, Ding Li, Yang Liu, Wen-Sheng Chen, Jinming Gao, Xiao-Qiang Li, Wei Cao

Nat Commun. 2022; 13: 7455. Published online 2022 Dec 2. doi: 10.1038/s41467-022-35242-0

PMCID:: PMC9718841

Abstract Article PDF–4.7M

Select item 95747777.

Store-operated Ca²⁺ entry and Ca²⁺ responses to hypothalamic releasing hormones in anterior pituitary cells from Orai1−/− and heptaTRPC knockout mice

Lucía Núñez, Gary S. Bird, Elena Hernando-Pérez, Enrique Pérez-Riesgo, James W. Putney, Jr, Carlos Villalobos

Biochim Biophys Acta Mol Cell Res. Author manuscript; available in PMC 2022 Oct 17.

Published in final edited form as: Biochim Biophys Acta Mol Cell Res. 2019 Jul; 1866(7): 1124–1136. Published online 2018 Nov 17. doi: 10.1016/j.bbamcr.2018.11.006

PMCID:: PMC9574777

Abstract Article PDF–1.8M

Select item 91199198.

TRPV4 and TRPC1 channels mediate the response to tensile strain in mouse Müller cells

Andrew O. Jo, Monika Lakk, Christopher N. Rudzitis, David Križaj

Cell Calcium. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: Cell Calcium. 2022 Jun; 104: 102588. Published online 2022 Apr 5. doi: 10.1016/j.ceca.2022.102588

PMCID:: PMC9119919

Abstract Article PDF–764K

Select item 89609279.

Lipidomic Analysis of TRPC1 Ca²⁺-Permeable Channel-Knock Out Mouse Demonstrates a Vital Role in Placental Tissue Sphingolipid and Triacylglycerol Homeostasis Under Maternal High-Fat Diet

Michael R. Bukowski, Brij B. Singh, James N. Roemmich, Kate J. Claycombe-Larson

Front Endocrinol (Lausanne) 2022; 13: 854269. Published online 2022 Mar 10. doi: 10.3389/fendo.2022.854269

Correction in:: Front Endocrinol (Lausanne). 2022; 13: 949419.

PMCID:: PMC8960927

Abstract Article PDF–2.5M

Select item 859142310.

Resolving macrophage polarization through distinct Ca²⁺ entry channel that maintains intracellular signaling and mitochondrial bioenergetics

Viviane Nascimento Da Conceicao, Yuyang Sun, Karthik Ramachandran, Arun Chauhan, Amritha Raveendran, Manigandan Venkatesan, Bony DeKumar, Soumya Maity, Neelanjan Vishnu, George A. Kotsakis, Paul F. Worley, Donald L. Gill, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh

iScience. 2021 Nov 19; 24(11): 103339. Published online 2021 Oct 23. doi: 10.1016/j.isci.2021.103339

PMCID:: PMC8591423

Abstract Article PDF–5.5M

Select item 823328311.

Mapping the expression of transient receptor potential channels across murine placental development

Katrien De Clercq, Vicente Pérez-García, Rieta Van Bree, Federica Pollastro, Karen Peeraer, Thomas Voets, Joris Vriens

Cell Mol Life Sci. 2021 Jun; 78(11): 4993–5014. Published online 2021 Apr 21. doi: 10.1007/s00018-021-03837-3

PMCID:: PMC8233283

Abstract Article PDF–4.1M

Select item 742601612.

Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced relaxations and nitric oxide production in mesenteric arteries: comparative study using wild-type and TRPC1^−/- mice

Harry Z.E. Greenberg, Simonette R.E. Carlton-Carew, Alexander K. Zargaran, Kazi S. Jahan, Lutz Birnbaumer, Anthony P. Albert

Channels (Austin) 2019; 13(1): 410–423. Published online 2019 Oct 11. doi: 10.1080/19336950.2019.1673131

PMCID:: PMC7426016

Abstract Article PDF–2.0M

Select item 732635313.

TRPM4 Conductances in Thalamic Reticular Nucleus Neurons Generate Persistent Firing during Slow Oscillations

John J. O'Malley, Frederik Seibt, Jeannie Chin, Michael Beierlein

J Neurosci. 2020 Jun 17; 40(25): 4813–4823. doi: 10.1523/JNEUROSCI.0324-20.2020

PMCID:: PMC7326353

Abstract Article PDF–2.0M

Select item 719087414.

RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways

Karina Formoso, Sebastian Susperreguy, Marc Freichel, Lutz Birnbaumer

Sci Rep. 2020; 10: 7227. Published online 2020 Apr 29. doi: 10.1038/s41598-020-61177-x

PMCID:: PMC7190874

Abstract Article PDF–4.0M

Select item 717663915.

Store-operated Ca²⁺ entry in primary murine lung fibroblasts is independent of classical transient receptor potential (TRPC) channels and contributes to cell migration

Larissa Bendiks, Fabienne Geiger, Thomas Gudermann, Stefan Feske, Alexander Dietrich

Sci Rep. 2020; 10: 6812. Published online 2020 Apr 22. doi: 10.1038/s41598-020-63677-2

PMCID:: PMC7176639

Abstract Article PDF–1.6M

Select item 715660116.

Analysis of Mrgprb2 Receptor-Evoked Ca²⁺ Signaling in Bone Marrow Derived (BMMC) and Peritoneal (PMC) Mast Cells of TRPC-Deficient Mice

Volodymyr Tsvilovskyy, Alejandra Solis-Lopez, Julia Almering, Christin Richter, Lutz Birnbaumer, Alexander Dietrich, Marc Freichel

Front Immunol. 2020; 11: 564. Published online 2020 Apr 8. doi: 10.3389/fimmu.2020.00564

PMCID:: PMC7156601

Abstract Article PDF–1.6M

Select item 714053017.

Transient Receptor Potential Canonical 5-Scramblase Signaling Complex Mediates Neuronal Phosphatidylserine Externalization and Apoptosis

Jizheng Guo, Jie Li, Lin Xia, Yang Wang, Jinhang Zhu, Juan Du, Yungang Lu, Guodong Liu, Xiaoqiang Yao, Bing Shen

Cells. 2020 Mar; 9(3): 547. Published online 2020 Feb 26. doi: 10.3390/cells9030547

PMCID:: PMC7140530

Abstract Article PDF–4.0M

Select item 707279418.

TRPC1 Regulates the Activity of a Voltage-Dependent Nonselective Cation Current in Hippocampal CA1 Neurons

Frauke Kepura, Eva Braun, Alexander Dietrich, Tim D. Plant

Cells. 2020 Feb; 9(2): 459. Published online 2020 Feb 18. doi: 10.3390/cells9020459

PMCID:: PMC7072794

Abstract Article PDF–2.4M

Select item 690270119.

Ambient and supplemental magnetic fields promote myogenesis via a TRPC1-mitochondrial axis: evidence of a magnetic mitohormetic mechanism

Jasmine Lye Yee Yap, Yee Kit Tai, Jürg Fröhlich, Charlene Hui Hua Fong, Jocelyn Naixin Yin, Zi Ling Foo, Sharanya Ramanan, Christian Beyer, Shi Jie Toh, Marco Casarosa, Narendra Bharathy, Monica Palanichamy Kala, Marcel Egli, Reshma Taneja, Chuen Neng Lee, Alfredo Franco-Obregón

FASEB J. 2019 Nov; 33(11): 12853–12872. Published online 2019 Sep 13. doi: 10.1096/fj.201900057R

PMCID:: PMC6902701

Abstract Article

Select item 677342220.

TRPC channels regulate Ca²⁺-signaling and short-term plasticity of fast glutamatergic synapses

Yvonne Schwarz, Katharina Oleinikov, Barbara Schindeldecker, Amanda Wyatt, Petra Weißgerber, Veit Flockerzi, Ulrich Boehm, Marc Freichel, Dieter Bruns

PLoS Biol. 2019 Sep; 17(9): e3000445. Published online 2019 Sep 19. doi: 10.1371/journal.pbio.3000445

PMCID:: PMC6773422

Abstract Article PDF–6.1M

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