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Select item 110950461.

NER-factor DDB2 regulates HIF1α and hypoxia-response genes in HNSCC

Prashant V. Bommi, Vaibhav Chand, Nishit K. Mukhopadhyay, Pradip Raychaudhuri, Srilata Bagchi

Oncogene. Author manuscript; available in PMC 2024 May 15.

Published in final edited form as: Oncogene. 2020 Feb; 39(8): 1784–1796. Published online 2019 Nov 18. doi: 10.1038/s41388-019-1105-y

PMCID:: PMC11095046

Abstract Article PDF–1.8M

Select item 105658762.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 104227133.

Brazilian XP-E siblings carrying a novel DDB2 variant developed early-onset melanoma: a case report

Ana Rafaela de Souza Timoteo, Isabel Cristina Pinheiro de Almeida, Andrey A Yurchenko, Sheila Ramos de Miranda Henriques, Paulo de Souza Segundo, Fatemeh Rajabi, Sergey Nikolaev, Tirzah Braz Petta

BMC Med Genomics. 2023; 16: 186. Published online 2023 Aug 12. doi: 10.1186/s12920-023-01622-8

PMCID:: PMC10422713

Abstract Article PDF–1.6M

Select item 98587044.

The Role of Alternative Splicing Factors, DDB2-Related Ageing and DNA Damage Repair in the Progression and Prognosis of Stomach Adenocarcinoma Patients

Xinshu Wang, Zhiyuan Huang, Lei Li, Yuntong Yang, Jiyuan Zhang, Li Wang, Jian Yuan, Yunhui Li

Genes (Basel) 2023 Jan; 14(1): 39. Published online 2022 Dec 23. doi: 10.3390/genes14010039

PMCID:: PMC9858704

Abstract Article PDF–2.8M

Select item 94727585.

Insight into Viral Hijacking of CRL4 Ubiquitin Ligase through Structural Analysis of the pUL145-DDB1 Complex

Elizaveta T. Wick, Colton J. Treadway, Zhijun Li, Nathan I. Nicely, Zhizhong Ren, Albert S. Baldwin, Yue Xiong, Joseph S. Harrison, Nicholas G. Brown

J Virol. 2022 Sep; 96(17): e00826-22. Published online 2022 Aug 8. doi: 10.1128/jvi.00826-22

PMCID:: PMC9472758

Abstract Article PDF–3.2M

Select item 92792856.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 92544797.

Hypoxia-inducible CircPFKFB4 Promotes Breast Cancer Progression by Facilitating the CRL4^DDB2 E3 Ubiquitin Ligase-mediated p27 Degradation

Hang Chen, Rui Yang, Lei Xing, Bin Wang, Dawei Liu, Xiaoqiang Ou, Yumei Deng, Rong Jiang, Junxia Chen

Int J Biol Sci. 2022; 18(9): 3888–3907. Published online 2022 Jun 6. doi: 10.7150/ijbs.72842

PMCID:: PMC9254479

Abstract Article PDF–5.0M

Select item 92140548.

Gentiopicroside targets PAQR3 to activate the PI3K/AKT signaling pathway and ameliorate disordered glucose and lipid metabolism

Haiming Xiao, Xiaohong Sun, Zeyuan Lin, Yan Yang, Meng Zhang, Zhanchi Xu, Peiqing Liu, Zhongqiu Liu, Heqing Huang

Acta Pharm Sin B. 2022 Jun; 12(6): 2887–2904. Published online 2022 Jan 6. doi: 10.1016/j.apsb.2021.12.023

PMCID:: PMC9214054

Abstract Article PDF–8.5M

Select item 91197369.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 905883610.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

Select item 889702211.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 886103712.

Global and transcription-coupled repair of 8-oxoG is initiated by nucleotide excision repair proteins

Namrata Kumar, Arjan F. Theil, Vera Roginskaya, Yasmin Ali, Michael Calderon, Simon C. Watkins, Ryan P. Barnes, Patricia L. Opresko, Alex Pines, Hannes Lans, Wim Vermeulen, Bennett Van Houten

Nat Commun. 2022; 13: 974. Published online 2022 Feb 21. doi: 10.1038/s41467-022-28642-9

PMCID:: PMC8861037

Abstract Article PDF–6.2M

Select item 879130113.

Proteomic Analysis of Nuclear Hepatitis B Virus Relaxed Circular DNA-Associated Proteins Identifies UV-Damaged DNA Binding Protein as a Host Factor Involved in Covalently Closed Circular DNA Formation

Alexander L. Marchetti, Hu Zhang, Elena S. Kim, Xiaoyang Yu, Sunbok Jang, Mu Wang, Haitao Guo

J Virol. 2022 Jan; 96(2): e01360-21. Prepublished online 2021 Oct 27. Published online 2022 Jan 26. doi: 10.1128/JVI.01360-21

PMCID:: PMC8791301

Abstract Article PDF–3.0M

Select item 846245814.

MEKK1-Dependent Activation of the CRL4 Complex Is Important for DNA Damage-Induced Degradation of p21 and DDB2 and Cell Survival

Susanne Bacher, Hilda Stekman, Carla M. Farah, Annika Karger, Michael Kracht, M. Lienhard Schmitz

Mol Cell Biol. 2021 Oct; 41(10): e00081-21. Prepublished online 2021 Jul 12. Published online 2021 Sep 24. doi: 10.1128/MCB.00081-21

PMCID:: PMC8462458

Abstract Article PDF–3.1M

Select item 816503015.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 808541816.

USP44 Stabilizes DDB2 to Facilitate Nucleotide Excision Repair and Prevent Tumors

Ying Zhang, Imke K. Mandemaker, Syota Matsumoto, Oded Foreman, Christopher P. Holland, Whitney R. Lloyd, Kaoru Sugasawa, Wim Vermeulen, Jurgen A. Marteijn, Paul J. Galardy

Front Cell Dev Biol. 2021; 9: 663411. Published online 2021 Apr 16. doi: 10.3389/fcell.2021.663411

PMCID:: PMC8085418

Abstract Article PDF–1.5M

Select item 787365917.

Expanding molecular roles of UV-DDB: shining light on genome stability and cancer

Maria Beecher, Namrata Kumar, Sunbok Jang, Vesna Rapić-Otrin, Bennett Van Houten

DNA Repair (Amst) Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: DNA Repair (Amst). 2020 Oct; 94: 102860. Published online 2020 Apr 27. doi: 10.1016/j.dnarep.2020.102860

PMCID:: PMC7873659

Abstract Article PDF–1.7M

Select item 786946118.

DDB2 regulates DNA replication through PCNA-independent degradation of CDT2

Xiaojun Wu, Min Yu, Zhuxia Zhang, Feng Leng, Yue Ma, Ni Xie, Fei Lu

Cell Biosci. 2021; 11: 34. Published online 2021 Feb 8. doi: 10.1186/s13578-021-00540-5

PMCID:: PMC7869461

Abstract Article PDF–2.7M

Select item 766518119.

Functional impacts of the ubiquitin–proteasome system on DNA damage recognition in global genome nucleotide excision repair

Wataru Sakai, Mayumi Yuasa-Sunagawa, Masayuki Kusakabe, Aiko Kishimoto, Takeshi Matsui, Yuki Kaneko, Jun-ichi Akagi, Nicolas Huyghe, Masae Ikura, Tsuyoshi Ikura, Fumio Hanaoka, Masayuki Yokoi, Kaoru Sugasawa

Sci Rep. 2020; 10: 19704. Published online 2020 Nov 12. doi: 10.1038/s41598-020-76898-2

PMCID:: PMC7665181

Abstract Article PDF–2.1M

Select item 752223120.

Ubiquitin and TFIIH-stimulated DDB2 dissociation drives DNA damage handover in nucleotide excision repair

Cristina Ribeiro-Silva, Mariangela Sabatella, Angela Helfricht, Jurgen A. Marteijn, Arjan F. Theil, Wim Vermeulen, Hannes Lans

Nat Commun. 2020; 11: 4868. Published online 2020 Sep 28. doi: 10.1038/s41467-020-18705-0

PMCID:: PMC7522231

Abstract Article PDF–5.3M

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