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Select item 112035451.

Bcl-2 Up-Regulation Mediates Taxane Resistance Downstream of APC Loss

Angelique R. Wise, Sara Maloney, Adam Hering, Sarah Zabala, Grace E. Richmond, Monica K. VanKlompenberg, Murlidharan T. Nair, Jenifer R. Prosperi

Int J Mol Sci. 2024 Jun; 25(12): 6745. Published online 2024 Jun 19. doi: 10.3390/ijms25126745

PMCID:: PMC11203545

Abstract Article PDF–1.5M

Select item 111585652.

Prognostic impact of immunohistochemical biomarkers in diffuse large B‐cell lymphoma in the rituximab era

Ritsuko Seki, Koichi Ohshima, Tomoaki Fujisaki, Naokuni Uike, Fumio Kawano, Hisashi Gondo, Shigeyoshi Makino, Tetsuya Eto, Yukiyoshi Moriuchi, Fumihiro Taguchi, Tomohiko Kamimura, Hiroyuki Tsuda, Ryosuke Ogawa, Kazuya Shimoda, Kiyoshi Yamashita, Keiko Suzuki, Hitoshi Suzushima, Kunihiro Tsukazaki, Masakazu Higuchi, Atae Utsunomiya, Masahiro Iwahashi, Yutaka Imamura, Kazuo Tamura, Junji Suzumiya, Minoru Yoshida, Yasunobu Abe, Tadashi Matsumoto, Takashi Okamura

Cancer Sci. 2009 Oct; 100(10): 1842–1847. Published online 2009 Jul 1. doi: 10.1111/j.1349-7006.2009.01268.x

PMCID:: PMC11158565

Abstract Article PDF–458K

Select item 111318873.

The antioxidant function of Bcl-2 preserves cytoskeletal stability of cells with defective respiratory complex I

A. M. Porcelli, A. Ghelli, L. Iommarini, E. Mariani, M. Hoque, C. Zanna, G. Gasparre, M. Rugolo

Cell Mol Life Sci. 2008 Sep; 65(18): 2943–2951. Published online 2008 Aug 11. doi: 10.1007/s00018-008-8300-2

PMCID:: PMC11131887

Abstract Article PDF–712K

Select item 110936214.

Bcl-2, via Its BH4 Domain, Blocks Apoptotic Signaling Mediated by Mitochondrial Ras

Gerald V. Denis, Qiang Yu, Peihong Ma, Linda Deeds, Douglas V. Faller, Chang-Yan Chen

J Biol Chem. Author manuscript; available in PMC 2024 May 14.

Published in final edited form as: J Biol Chem. 2003 Feb 21; 278(8): 5775–5785. Published online 2002 Dec 10. doi: 10.1074/jbc.M210202200

PMCID:: PMC11093621

Abstract Article PDF–1.2M

Select item 110916305.

GPX4 inhibits apoptosis of thyroid cancer cells through regulating the FKBP8/Bcl-2 axis

Tianfeng Dang, Jieqing Yu, Yanqing Yu, Junjie Jiang, Yang Shi, Simin Yu, Congli Peng, Xiang Min, Yuanping Xiong, Ping Long, Wensheng Zhou, Daofeng Dai

Cancer Biomark. 2024; 39(4): 349–360. Prepublished online 2023 Dec 19. Published online 2024 Apr 15. doi: 10.3233/CBM-230220

PMCID:: PMC11091630

Abstract Article PDF–9.2M

Select item 109858046.

Impact of MYC and BCL2 double expression on outcomes in primary CNS lymphoma: a UK multicenter analysis

Edward Poynton, Emily Chernucha, James Day, Catherine Prodger, David Hopkins, Pallav Rakesh, Tess O’Neill, Nisha Thakrar, Ayse Akarca, Esraa Jamal, Ayesha Ali, Amy A. Kirkwood, Sabine Pomplun, Teresa Marafioti, Maria Calaminici, Paul Greaves, Sridhar Chaganti, Pam McKay, Jeffery Smith, Toby A. Eyre, Nicolas Martinez-Calle, Kate Cwynarski, Christopher P. Fox, Jessica Okosun

Blood Adv. 2024 Apr 9; 8(7): 1772–1775. Published online 2023 Dec 3. doi: 10.1182/bloodadvances.2023011426

PMCID:: PMC10985804

Article PDF–436K

Select item 109824947.

Reduced expressions of apoptosis-related proteins TRAIL, Bcl-2, and TNFR1 in NK cells of juvenile-onset systemic lupus erythematosus patients: relations with disease activity, nephritis, and neuropsychiatric involvement

Bernadete L. Liphaus, Simone C. Silva, Patrícia Palmeira, Clovis A. Silva, Claudia Goldenstein-Schainberg, Magda Carneiro-Sampaio

Front Immunol. 2024; 15: 1327255. Published online 2024 Mar 18. doi: 10.3389/fimmu.2024.1327255

PMCID:: PMC10982494

Abstract Article PDF–4.5M

Select item 109646168.

Low expression of miR-182 caused by DNA hypermethylation accelerates acute lymphocyte leukemia development by targeting PBX3 and BCL2: miR-182 promoter methylation is a predictive marker for hypomethylation agents + BCL2 inhibitor venetoclax

Danyang Li, Yigang Yuan, Chen Meng, Zihan Lin, Min Zhao, Liuzhi Shi, Min Li, Daijiao Ye, Yue Cai, Xiaofei He, Haige Ye, Shujuan Zhou, Haixia Zhou, Shenmeng Gao

Clin Epigenetics. 2024; 16: 48. Published online 2024 Mar 26. doi: 10.1186/s13148-024-01658-2

PMCID:: PMC10964616

Abstract Article PDF–2.4M

Select item 108264499.

Qinglong Yang, Yingxue Lu, Ashuai Du

J Cell Mol Med. 2024 Jan; 28(2): e18046. Published online 2023 Dec 1. doi: 10.1111/jcmm.18046

PMCID:: PMC10826449

Abstract Article PDF–3.3M

Select item 1079872910.

Value of Bax and Bcl2 expression in peripheral blood mononuclear cells for clinical prognosis of patients with chronic heart failure

Yangang Chen, Shuiquan Li, Zhenwen Yang, Tianlu Wang, Fahui Yin, Xiangyu Zhao, Yong Zhang

Medicine (Baltimore) 2024 Jan 19; 103(3): e36943. Published online 2024 Jan 19. doi: 10.1097/MD.0000000000036943

PMCID:: PMC10798729

Abstract Article PDF–763K

Select item 1077252911.

Ubiquitin-proteasome pathway-mediated regulation of the Bcl-2 family: effects and therapeutic approaches

Galvin Le Qian Tang, Jolin Xiao Hui Lai, Shazib Pervaiz

Haematologica. 2024 Jan 1; 109(1): 33–43. Published online 2023 Aug 17. doi: 10.3324/haematol.2023.283730

PMCID:: PMC10772529

Abstract Article PDF–828K

Select item 1068956112.

The long non-coding RNA OTX2-AS1 promotes tumor growth and predicts response to BCL-2 inhibition in medulloblastoma

Nan Qin, Eunice Paisana, Daniel Picard, Gabriel Leprivier, Maike Langini, Carlos Custódia, Rita Cascão, Catleen Conrad, Mirko Peitzsch, Anja Stefanski, Kai Stühler, Ute Fischer, Claudia C. Faria, Sascha Dietrich, Guido Reifenberger, Marc Remke

J Neurooncol. 2023; 165(2): 329–342. Published online 2023 Nov 17. doi: 10.1007/s11060-023-04508-y

PMCID:: PMC10689561

Abstract Article PDF–4.5M

Select item 1067103713.

Analysis of the Polymorphisms and Expression Levels of the BCL2, BAX and c-MYC Genes in Patients with Ovarian Cancer

Piotr Józef Olbromski, Anna Bogacz, Marta Bukowska, Adam Kamiński, Rafał Moszyński, Piotr Pawlik, Anna Szeliga, Katarzyna Kotrych, Bogusław Czerny

Int J Mol Sci. 2023 Nov; 24(22): 16309. Published online 2023 Nov 14. doi: 10.3390/ijms242216309

PMCID:: PMC10671037

Abstract Article PDF–517K

Select item 1065792414.

Upregulation of XRCC1 DNA Repair Gene, Interleukin-8, and Bcl-2 Antiapoptotic Gene Levels in Kurdish Patients with Gastric Adenocarcinoma

Auni Kamal D, Fisal Shakir Agha N, Housein Z

Arch Razi Inst. 2023 Jun; 78(3): 989–995. Published online 2023 Jun 30. doi: 10.22092/ARI.2022.360240.2567

PMCID:: PMC10657924

Abstract Article PDF–524K

Select item 1061472415.

Overexpression of hsa_circ_0001861 inhibits pulmonary fibrosis through targeting mir-296-5p/bcL-2 binding component 3 axis

Tao Wu, Shikui Wu, Hailu Jiao, Jun Feng, Xiang Zeng

Eur J Histochem. 2023 Oct 2; 67(4): 3839. Published online 2023 Oct 2. doi: 10.4081/ejh.2023.3839

PMCID:: PMC10614724

Abstract Article PDF–1.3M

Select item 1059822716.

Structural insights for selective disruption of Beclin 1 binding to Bcl-2

Yun-Zu Pan, Qiren Liang, Diana R. Tomchick, Jef K. De Brabander, Josep Rizo

Commun Biol. 2023; 6: 1080. Published online 2023 Oct 24. doi: 10.1038/s42003-023-05467-w

PMCID:: PMC10598227

Abstract Article PDF–2.9M

Select item 1056462517.

Bcl-2 supports survival and metabolic fitness of quiescent tissue-resident ILC3

James I. King, Felipe Melo-Gonzalez, Bert Malengier-Devlies, Roser Tachó-Piñot, Marlene S Magalhaes, Suzanne H. Hodge, Xavier Romero Ros, Rebecca Gentek, Matthew R. Hepworth

Mucosal Immunol. 2023 Oct; 16(5): 658–670. doi: 10.1016/j.mucimm.2023.07.001

PMCID:: PMC10564625

Abstract Article PDF–2.5M

Select item 1048499918.

PLK1 as a cooperating partner for BCL2-mediated antiapoptotic program in leukemia

Kinjal Shah, Ahmad Nasimian, Mehreen Ahmed, Lina Al Ashiri, Linn Denison, Wondossen Sime, Katerina Bendak, Iryna Kolosenko, Valentina Siino, Fredrik Levander, Caroline Palm-Apergi, Ramin Massoumi, Richard B. Lock, Julhash U. Kazi

Blood Cancer J. 2023 Dec; 13(1): 139. Published online 2023 Sep 7. doi: 10.1038/s41408-023-00914-7

PMCID:: PMC10484999

Abstract Article PDF–3.6M

Select item 1035569319.

CircTLK1 alleviates oxygen-glucose deprivation/reperfusion induced apoptosis in HK-2 cells through miR-136-5p/Bcl2 signal axis

Liting Kuang, Anshang Lu, Shaojuan Yao

Ren Fail. 2023; 45(1): 2236219. Published online 2023 Jul 18. doi: 10.1080/0886022X.2023.2236219

PMCID:: PMC10355693

Abstract Article PDF–1.7M

Select item 1020278420.

MicroRNA-431-5p在胃癌组织中低表达：基于线粒体和Bax/Bcl-2/caspase3信号通路

吴佳明, 邓忠权, 朱奕, 窦广健, 李进, 黄立勇

Nan Fang Yi Ke Da Xue Xue Bao. 2023 Apr 20; 43(4): 537–543. Chinese. doi: 10.12122/j.issn.1673-4254.2023.04.05

PMCID:: PMC10202784

Abstract Article PDF–1.6M

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