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Select item 112099351.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111599282.

Rab5a overexpression promoting ovarian cancer cell proliferation may be associated with APPL1‐related epidermal growth factor signaling pathway

Zhen Zhao, Xiang‐Fan Liu, Hua‐Cheng Wu, Shu‐Biao Zou, Jia‐Yi Wang, Pei‐Hua Ni, Xin‐Hua Chen, Qi‐Shi Fan

Cancer Sci. 2010 Jun; 101(6): 1454–1462. Published online 2010 Mar 10. doi: 10.1111/j.1349-7006.2010.01558.x

PMCID:: PMC11159928

Abstract Article PDF–2.0M

Select item 110463563.

RAB5A in triple-negative breast cancer: a critical role in macrophage reshaping in an exosomal miR-21-dependent manner

Lei Qiao, Chao Dong, Wenlei Jia, Gang Sun

Endocr Relat Cancer. 2024 May 1; 31(5): e230257. Prepublished online 2024 Mar 12. Published online 2024 Apr 12. doi: 10.1530/ERC-23-0257

PMCID:: PMC11046356

Abstract Article PDF–6.1M

Select item 107562754.

A genome-wide CRISPR/Cas9 screen identifies a role for Rab5A and early endosomes in hepatitis E virus replication

Noémie Oechslin, Nathalie Da Silva, Maliki Ankavay, Darius Moradpour, Jérôme Gouttenoire

Proc Natl Acad Sci U S A. 2023 Dec 26; 120(52): e2307423120. Published online 2023 Dec 18. doi: 10.1073/pnas.2307423120

PMCID:: PMC10756275

Abstract Article PDF–7.2M

Select item 106411785.

HPIP and RUFY3 are noncanonical guanine nucleotide exchange factors of Rab5 to regulate endocytosis-coupled focal adhesion turnover

Saratchandra Singh Khumukcham, Vasudevarao Penugurti, Suresh Bugide, Anju Dwivedi, Anita Kumari, P.S. Kesavan, Sruchytha Kalali, Yasaswi Gayatri Mishra, Vakkalagadda A. Ramesh, Hampapathalu A. Nagarajaram, Aprotim Mazumder, Bramanandam Manavathi

J Biol Chem. 2023 Nov; 299(11): 105311. Published online 2023 Oct 4. doi: 10.1016/j.jbc.2023.105311

PMCID:: PMC10641178

Abstract Article PDF–4.6M

Select item 106147176.

Hepatitis B virus promotes its own replication by enhancing RAB5A-mediated dual activation of endosomal and autophagic vesicle pathways

Zhenyu Zhao, Zhen Wei, Jiaxin Zheng, Zhihong Li, Hecun Zou, Xiang Wen, Fahong Li, Xueyu Wang, Qian Huang, Huaqing Zeng, Hui Fan, Xuefei Cai, Jiming Zhang, Bei Jia, Ailong Huang, Mengji Lu, Yong Lin

Emerg Microbes Infect. 2023; 12(2): 2261556. Published online 2023 Sep 19. doi: 10.1080/22221751.2023.2261556

PMCID:: PMC10614717

Abstract Article PDF–4.7M

Select item 105859567.

Receptor-mediated internalization promotes increased endosome size and number in a RAB4- and RAB5-dependent manner

Naava Naslavsky, Steve Caplan

Eur J Cell Biol. Author manuscript; available in PMC 2023 Oct 19.

Published in final edited form as: Eur J Cell Biol. 2023 Sep; 102(3): 151339. Published online 2023 Jul 6. doi: 10.1016/j.ejcb.2023.151339

PMCID:: PMC10585956

Abstract Article PDF–941K

Select item 102722778.

USP33 promotes pancreatic cancer malignant phenotype through the regulation of TGFBR2/TGFβ signaling pathway

Xinyuan Liu, Jian Xu, Bingbing shen, Jichuan Xu, Jianxin Jiang

Cell Death Dis. 2023 Jun; 14(6): 362. Published online 2023 Jun 15. doi: 10.1038/s41419-023-05871-4

PMCID:: PMC10272277

Abstract Article PDF–9.4M

Select item 102374229.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1020916910.

A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells

Xue Li, Quan Jiang, Guiyu Song, Mahsa Nouri Barkestani, Qianxun Wang, Shaoxun Wang, Matthew Fan, Caodi Fang, Bo Jiang, Justin Johnson, Arnar Geirsson, George Tellides, Jordan S. Pober, Dan Jane-wit

Nat Commun. 2023; 14: 3002. Published online 2023 May 24. doi: 10.1038/s41467-023-38684-2

Correction in:: Nat Commun. 2023; 14: 3336.

Correction in:: Nat Commun. 2023; 14: 8404.

PMCID:: PMC10209169

Abstract Article PDF–4.2M

Select item 1019621911.

RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A‐YTHDF2‐dependent manner

Dingcheng Shen, Jinxin Lin, Yumo Xie, Zhuokai Zhuang, Gaopo Xu, Shaoyong Peng, Guannan Tang, Liangliang Bai, Mingxuan Zhu, Yu Zhang, Ziying Huang, Puning Wang, Xiaoxia Liu, Meijin Huang, Yanxin Luo, Xiaolin Wang, Huichuan Yu

Clin Transl Med. 2023 May; 13(5): e1279. Published online 2023 May 18. doi: 10.1002/ctm2.1279

PMCID:: PMC10196219

Abstract Article PDF–3.5M

Select item 1010506812.

Kai-Chen Wu, Nicholas D. Condon, Timothy A. Hill, Robert C. Reid, David P. Fairlie, Junxian Lim

J Innate Immun. 2023 Jan-Dec; 15(1): 468–484. Published online 2023 Mar 7. doi: 10.1159/000530012

PMCID:: PMC10105068

Abstract Article PDF–2.2M

Select item 994427013.

MTSS1 curtails lung adenocarcinoma immune evasion by promoting AIP4-mediated PD-L1 monoubiquitination and lysosomal degradation

Yuan Wang, Zhenchang Jia, Chenxi Liang, Yunfei He, Min Cong, Qiuyao Wu, Pu Tian, Dasa He, Xiang Miao, Beibei Sun, Yue Yin, Chao Peng, Feng Yao, Da Fu, Yajun Liang, Peiyuan Zhang, Hua Xiong, Guohong Hu

Cell Discov. 2023; 9: 20. Published online 2023 Feb 21. doi: 10.1038/s41421-022-00507-x

PMCID:: PMC9944270

Abstract Article PDF–3.2M

Select item 981601814.

ATP9A deficiency causes ADHD and aberrant endosomal recycling via modulating RAB5 and RAB11 activity

Tian Meng, Xiaoting Chen, Zhengjie He, Haofeng Huang, Shiyin Lin, Kunru Liu, Guo Bai, Hao Liu, Mindong Xu, Haixia Zhuang, Yunlong Zhang, Ahmed Waqas, Qian Liu, Chuan Zhang, Xiang-Dong Sun, Huansen Huang, Muhammad Umair, Yousheng Yan, Du Feng

Mol Psychiatry. 2023; 28(3): 1219–1231. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01940-w

PMCID:: PMC9816018

Abstract Article PDF–6.6M

Select item 977255815.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 968395916.

Identification of Key Genes and miRNAs Affecting Osteosarcoma Based on Bioinformatics

Le Li, Xin Zhou, Wencan Zhang, Ran Zhao

Dis Markers. 2022; 2022: 1015593. Published online 2022 Nov 16. doi: 10.1155/2022/1015593

PMCID:: PMC9683959

Abstract Article PDF–2.1M

Select item 947545317.

The N⁶-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2

Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue

Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600

PMCID:: PMC9475453

Abstract Article PDF–4.4M

Select item 927928518.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 916548719.

RNF115 Inhibits the Post‐ER Trafficking of TLRs and TLRs‐Mediated Immune Responses by Catalyzing K11‐Linked Ubiquitination of RAB1A and RAB13

Zhi‐Dong Zhang, Hong‐Xu Li, Hu Gan, Zhen Tang, Yu‐Yao Guo, Shu‐Qi Yao, Tianzi Liuyu, Bo Zhong, Dandan Lin

Adv Sci (Weinh) 2022 Jun; 9(16): 2105391. Published online 2022 Mar 28. doi: 10.1002/advs.202105391

PMCID:: PMC9165487

Abstract Article PDF–7.5M

Select item 911973620.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

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