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Items: 1 to 20 of 235

1.
FANCD2 genome binding is nonrandom and is enriched at large transcriptionally active neural genes prone to copy number variation
Justin L. Blaize, Jada Lauren N. Garzon, Niall G. Howlett
Funct Integr Genomics. 2024; 24(5): 180. Published online 2024 Oct 4. doi: 10.1007/s10142-024-01453-5
PMCID:
PMC11452531
AbstractArticlePDF–7.8M
2.
FANCD2–FANCI surveys DNA and recognizes double- to single-stranded junctions
Pablo Alcón, Artur P. Kaczmarczyk, Korak Kumar Ray, Themistoklis Liolios, Guillaume Guilbaud, Tamara Sijacki, Yichao Shen, Stephen H. McLaughlin, Julian E. Sale, Puck Knipscheer, David S. Rueda, Lori A. Passmore
Nature. 2024; 632(8027): 1165–1173. Published online 2024 Jul 31. doi: 10.1038/s41586-024-07770-w
PMCID:
PMC11358013
AbstractArticlePDF–27M
3.
DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples
Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang
J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.
Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832
PMCID:
PMC11296914
AbstractArticlePDF–1.7M
4.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
5.
Comparative interactome analysis of α-arrestin families in human and Drosophila
Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam
eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328
PMCID:
PMC10945707
AbstractArticlePDF–2.8M
6.
Pancancer analysis of the prognostic and immunological role of FANCD2: a potential target for carcinogenesis and survival
Zedan Zhao, Ruyu Wang, Ruixue Wang, Jialing Song, Fengjun Ma, Huafeng Pan, Cuiyun Gao, Deqiang Wang, Xuemei Chen, Xiangzhen Fan
BMC Med Genomics. 2024; 17: 69. Published online 2024 Mar 5. doi: 10.1186/s12920-024-01836-4
Correction in:
BMC Med Genomics. 2024; 17: 129.
PMCID:
PMC10916239
AbstractArticlePDF–12M
7.
FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination
Wendy Leung, Ryan M. Baxley, Emma Traband, Ya-Chu Chang, Colette B. Rogers, Liangjun Wang, Wesley Durrett, Kendall S. Bromley, Lidia Fiedorowicz, Tanay Thakar, Anika Tella, Alexandra Sobeck, Eric A. Hendrickson, George-Lucian Moldovan, Naoko Shima, Anja-Katrin Bielinsky
Cell Rep. Author manuscript; available in PMC 2024 Feb 5.
Published in final edited form as: Cell Rep. 2023 Dec 26; 42(12): 113523. Published online 2023 Dec 5. doi: 10.1016/j.celrep.2023.113523
PMCID:
PMC10842461
AbstractArticlePDF–2.2M
8.
Mitotic DNA synthesis in untransformed human cells preserves common fragile site stability via a FANCD2-driven mechanism that requires HELQ
Emma L. Traband, Sarah R. Hammerlund, Mohammad Shameem, Ananya Narayan, Sanjiv Ramana, Anika Tella, Alexandra Sobeck, Naoko Shima
J Mol Biol. Author manuscript; available in PMC 2024 Nov 15.
Published in final edited form as: J Mol Biol. 2023 Nov 15; 435(22): 168294. Published online 2023 Sep 28. doi: 10.1016/j.jmb.2023.168294
PMCID:
PMC10839910
AbstractArticlePDF–1.3M
9.
FBXL12 degrades FANCD2 to regulate replication recovery and promote cancer cell survival under conditions of replication stress
Andrä Brunner, Qiuzhen Li, Samuele Fisicaro, Alexandros Kourtesakis, Johanna Viiliäinen, Henrik J. Johansson, Vijaya Pandey, Adarsh K. Mayank, Janne Lehtiö, James A. Wohlschlegel, Charles Spruck, Juha K. Rantala, Lukas M. Orre, Olle Sangfelt
Mol Cell. Author manuscript; available in PMC 2024 Oct 19.
Published in final edited form as: Mol Cell. 2023 Oct 19; 83(20): 3720–3739.e8. Published online 2023 Aug 16. doi: 10.1016/j.molcel.2023.07.026
PMCID:
PMC10592106
AbstractArticlePDF–2.5M
10.
FANCD2 as a novel prognostic biomarker correlated with immune and drug therapy in Hepatitis B-related hepatocellular carcinoma
Xiaowei Tang, Bei Luo, Shu Huang, Jiao Jiang, Yuan Chen, Wensen Ren, Xiaomin Shi, Wei Zhang, Lei Shi, Xiaolin Zhong, Muhan Lü
Eur J Med Res. 2023; 28: 419. Published online 2023 Oct 11. doi: 10.1186/s40001-023-01411-0
PMCID:
PMC10566141
AbstractArticlePDF–4.6M
11.
FANCD2 and RAD51 recombinase directly inhibit DNA2 nuclease at stalled replication forks and FANCD2 acts as a novel RAD51 mediator in strand exchange to promote genome stability
Wenpeng Liu, Piotr Polaczek, Ivan Roubal, Yuan Meng, Won-chae Choe, Marie-Christine Caron, Carl A Sedgeman, Yu Xi, Changwei Liu, Qiong Wu, Li Zheng, Jean-Yves Masson, Binghui Shen, Judith L Campbell
Nucleic Acids Res. 2023 Sep 22; 51(17): 9144–9165. Published online 2023 Aug 1. doi: 10.1093/nar/gkad624
PMCID:
PMC10516637
AbstractArticlePDF–2.0M
12.
HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways
Julie K. Monda, Xuezhen Ge, Moritz Hunkeler, Katherine A. Donovan, Michelle W. Ma, Cyrus Y. Jin, Marilyn Leonard, Eric S. Fischer, Eric J. Bennett
Cell Rep. Author manuscript; available in PMC 2023 Jun 19.
Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112496. Published online 2023 May 9. doi: 10.1016/j.celrep.2023.112496
PMCID:
PMC10279472
AbstractArticlePDF–2.9M
13.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
14.
SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage
Fengli Wang, Lingjuan Wang, Shiming Gan, Shenglei Feng, Sijin Ouyang, Xiaoli Wang, Shuiqiao Yuan
Research (Wash D C) 2023; 6: 0091. Published online 2023 Apr 12. doi: 10.34133/research.0091
PMCID:
PMC10202183
AbstractArticlePDF–18M
15.
CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment
Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini
Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3
PMCID:
PMC9950183
AbstractArticlePDF–2.4M
16.
FANCD2 inhibits ferroptosis by regulating the JAK2/STAT3 pathway in osteosarcoma
Xujun Li, Jiangyi Liu
BMC Cancer. 2023; 23: 179. Published online 2023 Feb 22. doi: 10.1186/s12885-023-10626-7
PMCID:
PMC9945409
AbstractArticlePDF–6.5M
17.
Structural and biochemical basis of interdependent FANCI‐FANCD2 ubiquitination
Kimon Lemonidis, Martin L Rennie, Connor Arkinson, Viduth K Chaugule, Mairi Clarke, James Streetley, Helen Walden
EMBO J. 2023 Feb; 42(3): e111898. Published online 2022 Nov 17. doi: 10.15252/embj.2022111898
PMCID:
PMC9890228
AbstractArticlePDF–6.8M
18.
FANCD2 promotes mitotic rescue from transcription-mediated replication stress in SETX-deficient cancer cells
Maha Said, Viviana Barra, Elisa Balzano, Ibtissam Talhaoui, Franca Pelliccia, Simona Giunta, Valeria Naim
Commun Biol. 2022; 5: 1395. Published online 2022 Dec 21. doi: 10.1038/s42003-022-04360-2
PMCID:
PMC9772326
AbstractArticlePDF–2.4M
19.
RAD18 opposes transcription-associated genome instability through FANCD2 recruitment
James P. Wells, Emily Yun-Chia Chang, Leticia Dinatto, Justin White, Stephanie Ryall, Peter C. Stirling
PLoS Genet. 2022 Dec; 18(12): e1010309. Published online 2022 Dec 8. doi: 10.1371/journal.pgen.1010309
PMCID:
PMC9767342
AbstractArticlePDF–10M
20.
SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis
Jun-yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A. Kane, Peixin Yang, Zhe Han
Commun Biol. 2022; 5: 1039. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03986-6
PMCID:
PMC9523645
AbstractArticlePDF–3.9M

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