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Select item 107182851.

Phospholipids can regulate complex I assembly independent of their role in maintaining mitochondrial membrane integrity

Anjaneyulu Murari, Shauna-Kay Rhooms, Divya Vimal, Kaniz Fatima Binte Hossain, Sanjay Saini, Maximino Villanueva, Michael Schlame, Edward Owusu-Ansah

Cell Rep. Author manuscript; available in PMC 2023 Dec 13.

Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112846. Published online 2023 Jul 29. doi: 10.1016/j.celrep.2023.112846

PMCID:: PMC10718285

Abstract Article PDF–2.8M

Select item 106228402.

Cardiolipin prolongs the lifetimes of respiratory proteins in Drosophila flight muscle

Mindong Ren, Yang Xu, Colin K.L. Phoon, Hediye Erdjument-Bromage, Thomas A. Neubert, Michael Schlame

J Biol Chem. 2023 Oct; 299(10): 105241. Published online 2023 Sep 9. doi: 10.1016/j.jbc.2023.105241

PMCID:: PMC10622840

Abstract Article PDF–1.2M

Select item 100361223.

Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state

Abhilash Padavannil, Anjaneyulu Murari, Shauna-Kay Rhooms, Edward Owusu-Ansah, James A Letts

eLife. 2023; 12: e84415. Published online 2023 Mar 23. doi: 10.7554/eLife.84415

PMCID:: PMC10036122

Abstract Article PDF–12M

Select item 99772794.

Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster

Ahmed-Noor A Agip, Injae Chung, Alvaro Sanchez-Martinez, Alexander J Whitworth, Judy Hirst

eLife. 2023; 12: e84424. Published online 2023 Jan 9. doi: 10.7554/eLife.84424

PMCID:: PMC9977279

Abstract Article PDF–6.3M

Select item 99151205.

Mutations in Complex I of the Mitochondrial Electron-Transport Chain Sensitize the Fruit Fly (Drosophila melanogaster) to Ether and Non-Ether Volatile Anesthetics

Luke A. Borchardt, Amanda R. Scharenbrock, Zachariah P. G. Olufs, David A. Wassarman, Misha Perouansky

Int J Mol Sci. 2023 Feb; 24(3): 1843. Published online 2023 Jan 17. doi: 10.3390/ijms24031843

PMCID:: PMC9915120

Abstract Article PDF–2.2M

Select item 97947286.

The membrane domain of respiratory complex I accumulates during muscle aging in Drosophila melanogaster

Kaniz Fatima Binte Hossain, Anjaneyulu Murari, Bibhuti Mishra, Edward Owusu-Ansah

Sci Rep. 2022; 12: 22433. Published online 2022 Dec 27. doi: 10.1038/s41598-022-26414-5

PMCID:: PMC9794728

Abstract Article PDF–3.7M

Select item 97134317.

Transcriptome analysis of FOXO-dependent hypoxia gene expression identifies Hipk as a regulator of low oxygen tolerance in Drosophila

Kate Ding, Elizabeth C Barretto, Michael Johnston, Byoungchun Lee, Marco Gallo, Savraj S Grewal

G3 (Bethesda) 2022 Dec; 12(12): jkac263. Published online 2022 Oct 6. doi: 10.1093/g3journal/jkac263

PMCID:: PMC9713431

Abstract Article PDF–1.0M

Select item 96440648.

Loss of Drosophila Clueless differentially affects the mitochondrial proteome compared to loss of Sod2 and Pink1

Aditya Sen, Rachel T. Cox

Front Physiol. 2022; 13: 1004099. Published online 2022 Oct 26. doi: 10.3389/fphys.2022.1004099

PMCID:: PMC9644064

Abstract Article PDF–4.2M

Select item 90946679.

IDH2-mediated regulation of the biogenesis of the oxidative phosphorylation system

Anjaneyulu Murari, Naga S. V. Goparaju, Shauna-Kay Rhooms, Kaniz F. B. Hossain, Felix G. Liang, Christian J. Garcia, Cindy Osei, Tong Liu, Hong Li, Richard N. Kitsis, Rajesh Patel, Edward Owusu-Ansah

Sci Adv. 2022 May; 8(19): eabl8716. Published online 2022 May 11. doi: 10.1126/sciadv.abl8716

PMCID:: PMC9094667

Abstract Article PDF–21M

Select item 903811910.

Targeting metabolic pathways for extension of lifespan and healthspan across multiple species

Andrey A. Parkhitko, Elizabeth Filine, Stephanie E. Mohr, Alexey Moskalev, Norbert Perrimon

Ageing Res Rev. Author manuscript; available in PMC 2022 Apr 25.

Published in final edited form as: Ageing Res Rev. 2020 Dec; 64: 101188. Published online 2020 Oct 5. doi: 10.1016/j.arr.2020.101188

PMCID:: PMC9038119

Abstract Article PDF–2.0M

Select item 866448611.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 858397712.

Exercising D. melanogaster Modulates the Mitochondrial Proteome and Physiology. The Effect on Lifespan Depends upon Age and Sex

Brad Ebanks, Ying Wang, Gunjan Katyal, Chloe Sargent, Thomas L. Ingram, Antonia Bowman, Nicoleta Moisoi, Lisa Chakrabarti

Int J Mol Sci. 2021 Nov; 22(21): 11606. Published online 2021 Oct 27. doi: 10.3390/ijms222111606

PMCID:: PMC8583977

Abstract Article PDF–1.7M

Select item 846882713.

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders

Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D’Avino, Maria Grazia Giansanti

Cells. 2021 Sep; 10(9): 2336. Published online 2021 Sep 6. doi: 10.3390/cells10092336

PMCID:: PMC8468827

Abstract Article PDF–4.1M

Select item 834666614.

Dissecting the concordant and disparate roles of NDUFAF3 and NDUFAF4 in mitochondrial complex I biogenesis

Anjaneyulu Murari, Shauna-Kay Rhooms, Christian Garcia, Tong Liu, Hong Li, Bibhuti Mishra, Cassie Deshong, Edward Owusu-Ansah

iScience. 2021 Aug 20; 24(8): 102869. Published online 2021 Jul 16. doi: 10.1016/j.isci.2021.102869

PMCID:: PMC8346666

Abstract Article PDF–6.1M

Select item 774410015.

Downregulation of the tyrosine degradation pathway extends Drosophila lifespan

Andrey A Parkhitko, Divya Ramesh, Lin Wang, Dmitry Leshchiner, Elizabeth Filine, Richard Binari, Abby L Olsen, John M Asara, Valentin Cracan, Joshua D Rabinowitz, Axel Brockmann, Norbert Perrimon

eLife. 2020; 9: e58053. Published online 2020 Dec 15. doi: 10.7554/eLife.58053

PMCID:: PMC7744100

Abstract Article PDF–1.8M

Select item 765970916.

An antibody toolbox to track complex I assembly defines AIF’s mitochondrial function

Anjaneyulu Murari, Shauna-Kay Rhooms, Naga Sri Goparaju, Maximino Villanueva, Edward Owusu-Ansah

J Cell Biol. 2020 Oct 5; 219(10): e202001071. Published online 2020 Sep 16. doi: 10.1083/jcb.202001071

PMCID:: PMC7659709

Abstract Article PDF–7.1M

Select item 736287917.

MISTERMINATE Mechanistically Links Mitochondrial Dysfunction with Proteostasis Failure

Zhihao Wu, Ishaq Tantray, Junghyun Lim, Songjie Chen, Yu Li, Zoe Davis, Cole Sitron, Jason Dong, Suzana Gispert, Georg Auburger, Onn Brandman, Xiaolin Bi, Michael Snyder, Bingwei Lu

Mol Cell. Author manuscript; available in PMC 2020 Jul 15.

Published in final edited form as: Mol Cell. 2019 Aug 22; 75(4): 835–848.e8. Published online 2019 Aug 1. doi: 10.1016/j.molcel.2019.06.031