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Items: 1 to 20 of 26

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
The adhesion GPCR GPR116/ADGRF5 has a dual function in pancreatic islets regulating somatostatin release and islet development
Juliane Röthe, Robert Kraft, Albert Ricken, Isabell Kaczmarek, Madlen Matz-Soja, Karsten Winter, André Nguyen Dietzsch, Julia Buchold, Marie-Gabrielle Ludwig, Ines Liebscher, Torsten Schöneberg, Doreen Thor
Commun Biol. 2024; 7: 104. Published online 2024 Jan 16. doi: 10.1038/s42003-024-05783-9
PMCID:
PMC10791652
AbstractArticlePDF–4.0M
3.
The transcription factor Foxi1 promotes expression of V-ATPase and Gpr116 in M-1 cells
Mackenzie Kui, Jennifer L. Pluznick, Nathan A. Zaidman
Am J Physiol Renal Physiol. 2023 Mar 1; 324(3): F267–F273. Published online 2023 Jan 5. doi: 10.1152/ajprenal.00272.2022
PMCID:
PMC9942906
AbstractArticle
4.
Regulation of pulmonary surfactant by the adhesion GPCR GPR116/ADGRF5 requires a tethered agonist-mediated activation mechanism
James P Bridges, Caterina Safina, Bernard Pirard, Kari Brown, Alyssa Filuta, Ravichandran Panchanathan, Rochdi Bouhelal, Nicole Reymann, Sejal Patel, Klaus Seuwen, William E Miller, Marie-Gabrielle Ludwig
eLife. 2022; 11: e69061. Published online 2022 Sep 8. doi: 10.7554/eLife.69061
PMCID:
PMC9489211
AbstractArticlePDF–2.6M
5.
Orphan G-Protein Coupled Receptor GPRC5B Is Critical for Lymphatic Development
Wenjing Xu, Nathan P. Nelson-Maney, László Bálint, Hyouk-Bum Kwon, Reema B. Davis, Danielle C. M. Dy, James M. Dunleavey, Brad St. Croix, Kathleen M. Caron
Int J Mol Sci. 2022 May; 23(10): 5712. Published online 2022 May 20. doi: 10.3390/ijms23105712
PMCID:
PMC9146384
AbstractArticlePDF–3.9M
6.
Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue
Anastasia Georgiadi, Valeria Lopez-Salazar, Rabih El- Merahbi, Rhoda Anane Karikari, Xiaochuan Ma, André Mourão, Katarina Klepac, Lea Bühler, Ana Jimena Alfaro, Isabell Kaczmarek, Adam Linford, Madeleen Bosma, Olga Shilkova, Olli Ritvos, Nobuhiro Nakamura, Shigehisa Hirose, Maximilian Lassi, Raffaele Teperino, Juliano Machado, Marcel Scheideler, Arne Dietrich, Arie Geerlof, Annette Feuchtinger, Andreas Blutke, Katrin Fischer, Timo Dirk Müller, Katharina Kessler, Torsten Schöneberg, Doreen Thor, Silke Hornemann, Michael Kruse, Peter Nawroth, Olga Pivovarova-Ramich, Andreas Friedrich Hermann Pfeiffer, Michael Sattler, Matthias Blüher, Stephan Herzig
Nat Commun. 2021; 12: 2999. Published online 2021 May 20. doi: 10.1038/s41467-021-22579-1
PMCID:
PMC8137956
AbstractArticlePDF–3.1M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
Adhesion-GPCR Gpr116 (ADGRF5) expression inhibits renal acid secretion
Nathan A. Zaidman, Viktor N. Tomilin, Naghmeh Hassanzadeh Khayyat, Mahendra Damarla, Josephine Tidmore, Diane E. Capen, Dennis Brown, Oleh M. Pochynyuk, Jennifer L. Pluznick
Proc Natl Acad Sci U S A. 2020 Oct 20; 117(42): 26470–26481. Published online 2020 Oct 1. doi: 10.1073/pnas.2007620117
PMCID:
PMC7584995
AbstractArticlePDF–2.6M
9.
Adgrf5 contributes to patterning of the endothelial deep layer in retina
C. Niaudet, M. Petkova, B. Jung, S. Lu, B. Laviña, S. Offermanns, C. Brakebusch, C. Betsholtz
Angiogenesis. 2019; 22(4): 491–505. Published online 2019 Jun 29. doi: 10.1007/s10456-019-09674-0
PMCID:
PMC6863953
AbstractArticlePDF–12M
10.
Loss of the adhesion G-protein coupled receptor ADGRF5 in mice induces airway inflammation and the expression of CCL2 in lung endothelial cells
Fumimasa Kubo, Donna Maretta Ariestanti, Souta Oki, Taku Fukuzawa, Ryotaro Demizu, Tomoya Sato, Rahmaningsih Mara Sabirin, Shigehisa Hirose, Nobuhiro Nakamura
Respir Res. 2019; 20: 11. Published online 2019 Jan 17. doi: 10.1186/s12931-019-0973-6
PMCID:
PMC6337809
AbstractArticlePDF–5.1M
11.
Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4)
Shun Lu, Shuya Liu, Astrid Wietelmann, Baktybek Kojonazarov, Ann Atzberger, Cong Tang, Ralph Theo Schermuly, Hermann-Josef Gröne, Stefan Offermanns
PLoS One. 2017; 12(8): e0183166. Published online 2017 Aug 14. doi: 10.1371/journal.pone.0183166
PMCID:
PMC5555693
AbstractArticlePDF–30M
12.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
13.
Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium
Colin Niaudet, Jennifer J. Hofmann, Maarja A. Mäe, Bongnam Jung, Konstantin Gaengel, Michael Vanlandewijck, Elisabet Ekvärn, M. Dolores Salvado, Annika Mehlem, Sahar Al Sayegh, Liqun He, Thibaud Lebouvier, Marco Castro-Freire, Kan Katayama, Kjell Hultenby, Christine Moessinger, Philip Tannenberg, Sara Cunha, Kristian Pietras, Bàrbara Laviña, JongWook Hong, Tove Berg, Christer Betsholtz
PLoS One. 2015; 10(9): e0137949. Published online 2015 Sep 22. doi: 10.1371/journal.pone.0137949
PMCID:
PMC4579087
AbstractArticlePDF–19M
14.
Targeted Disruption of Ig-Hepta/Gpr116 Causes Emphysema-like Symptoms That Are Associated with Alveolar Macrophage Activation
Donna Maretta Ariestanti, Hikaru Ando, Shigehisa Hirose, Nobuhiro Nakamura
J Biol Chem. 2015 Apr 24; 290(17): 11032–11040. Published online 2015 Mar 16. doi: 10.1074/jbc.M115.648311
PMCID:
PMC4409263
AbstractArticlePDF–1.2M
15.
International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein–Coupled Receptors
Jörg Hamann, Gabriela Aust, Demet Araç, Felix B. Engel, Caroline Formstone, Robert Fredriksson, Randy A. Hall, Breanne L. Harty, Christiane Kirchhoff, Barbara Knapp, Arunkumar Krishnan, Ines Liebscher, Hsi-Hsien Lin, David C. Martinelli, Kelly R. Monk, Miriam C. Peeters, Xianhua Piao, Simone Prömel, Torsten Schöneberg, Thue W. Schwartz, Kathleen Singer, Martin Stacey, Yuri A. Ushkaryov, Mario Vallon, Uwe Wolfrum, Mathew W. Wright, Lei Xu, Tobias Langenhan, Helgi B. Schiöth
Pharmacol Rev. 2015 Apr; 67(2): 338–367. Published online 2015 Apr. doi: 10.1124/pr.114.009647
PMCID:
PMC4394687
AbstractArticlePDF–3.0M
16.
Expression of the Immunoglobulin Superfamily Cell Adhesion Molecules in the Developing Spinal Cord and Dorsal Root Ganglion
Zirong Gu, Fumiyasu Imai, In Jung Kim, Hiroko Fujita, Kei ichi Katayama, Kensaku Mori, Yoshihiro Yoshihara, Yutaka Yoshida
PLoS One. 2015; 10(3): e0121550. Published online 2015 Mar 31. doi: 10.1371/journal.pone.0121550
PMCID:
PMC4380438
AbstractArticlePDF–36M
17.
Orphan G Protein–Coupled Receptor GPR116 Regulates Pulmonary Surfactant Pool Size
James P. Bridges, Marie-Gabrielle Ludwig, Matthias Mueller, Bernd Kinzel, Atsuyasu Sato, Yan Xu, Jeffrey A. Whitsett, Machiko Ikegami
Am J Respir Cell Mol Biol. 2013 Sep; 49(3): 348–357. doi: 10.1165/rcmb.2012-0439OC
PMCID:
PMC3824053
AbstractArticlePDF–1.1M
18.
Lung Surfactant Levels are Regulated by Ig-Hepta/GPR116 by Monitoring Surfactant Protein D
Taku Fukuzawa, Junji Ishida, Akira Kato, Taro Ichinose, Donna Maretta Ariestanti, Tomoya Takahashi, Kunitoshi Ito, Jumpei Abe, Tomohiro Suzuki, Shigeharu Wakana, Akiyoshi Fukamizu, Nobuhiro Nakamura, Shigehisa Hirose
PLoS One. 2013; 8(7): e69451. Published online 2013 Jul 29. doi: 10.1371/journal.pone.0069451
PMCID:
PMC3726689
AbstractArticlePDF–12M
19.
Essential Regulation of Lung Surfactant Homeostasis by the Orphan G-protein Coupled Receptor GPR116
Mi Young Yang, Mary Beth Hilton, Steven Seaman, Diana C. Haines, Kunio Nagashima, Christina M. Burks, Lino Tessarollo, Pavlina T. Ivanova, H. Alex Brown, Todd M. Umstead, Joanna Floros, Zissis C. Chroneos, Brad St. Croix
Cell Rep. Author manuscript; available in PMC 2013 Jun 28.
Published in final edited form as: Cell Rep. 2013 May 30; 3(5): 1457–1464. Published online 2013 May 16. doi: 10.1016/j.celrep.2013.04.019
PMCID:
PMC3695742
AbstractArticlePDF–2.1M
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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