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Items: 1 to 20 of 146

1.
Role of the mitochondrial protein cyclophilin D in skin wound healing and collagen secretion
Ritu Bansal, Monica Torres, Matthew Hunt, Nuoqi Wang, Margarita Chatzopoulou, Mansi Manchanda, Evan P. Taddeo, Cynthia Shu, Orian S. Shirihai, Etty Bachar-Wikstrom, Jakob D. Wikstrom
JCI Insight. 2024 May 8; 9(9): e169213. Published online 2024 Apr 2. doi: 10.1172/jci.insight.169213
PMCID:
PMC11141914
AbstractArticlePDF–28M
2.
Cyclophilin D knockout significantly prevents HCC development in a streptozotocin-induced mouse model of diabetes-linked NASH
Winston T. Stauffer, Michael Bobardt, Daren R. Ure, Robert T. Foster, Philippe Gallay
PLoS One. 2024; 19(4): e0301711. Published online 2024 Apr 4. doi: 10.1371/journal.pone.0301711
PMCID:
PMC10994289
AbstractArticlePDF–3.0M
3.
Coordinated metabolic responses to cyclophilin D deletion in the developing heart
Gisela Beutner, Jonathan Ryan Burris, Michael P. Collins, Chaitanya A. Kulkarni, Sergiy M. Nadtochiy, Karen L. de Mesy Bentley, Ethan D. Cohen, Paul S. Brookes, George A. Porter, Jr.
iScience. 2024 Mar 15; 27(3): 109157. Published online 2024 Feb 9. doi: 10.1016/j.isci.2024.109157
PMCID:
PMC10897919
AbstractArticlePDF–5.5M
4.
Inhibition of mitochondrial cyclophilin D, a downstream target of glycogen synthase kinase 3α, improves sperm motility
Seung Hyun Park, Myung Chan Gye
Reprod Biol Endocrinol. 2024; 22: 15. Published online 2024 Jan 22. doi: 10.1186/s12958-024-01186-x
PMCID:
PMC10802072
AbstractArticlePDF–4.4M
5.
CypD induced ROS output promotes intracranial aneurysm formation and rupture by 8-OHdG/NLRP3/MMP9 pathway
Haiyan Fan, Hao Tian, Fa Jin, Xin Zhang, Shixing Su, Yanchao Liu, Zhuohua Wen, Xuying He, Xifeng Li, Chuanzhi Duan
Redox Biol. 2023 Nov; 67: 102887. Published online 2023 Sep 12. doi: 10.1016/j.redox.2023.102887
PMCID:
PMC10514219
AbstractArticlePDF–13M
6.
Cyclophilin D as a potential therapeutic target of liver ischemia/reperfusion injury by mediating crosstalk between apoptosis and autophagy
Mengjiao Yang, Zhihui Wang, Jin Xie, Md. Reyad‐ul‐Ferdous, Siying Li, Yongfeng Song
Chronic Dis Transl Med. 2023 Sep; 9(3): 238–249. Published online 2023 Jun 11. doi: 10.1002/cdt3.78
PMCID:
PMC10497823
AbstractArticlePDF–4.1M
7.
ANT-dependent MPTP underlies necrotic myofiber death in muscular dystrophy
Michael J. Bround, Julian R. Havens, Allen J. York, Michelle A. Sargent, Jason Karch, Jeffery D. Molkentin
Sci Adv. 2023 Aug; 9(34): eadi2767. Published online 2023 Aug 25. doi: 10.1126/sciadv.adi2767
PMCID:
PMC10456852
AbstractArticlePDF–1.2M
8.
Mitochondrial membrane potential instability on reperfusion after ischemia does not depend on mitochondrial Ca2+ uptake
Deepthi Ashok, Kyriakos Papanicolaou, Agnieszka Sidor, Michelle Wang, Soroosh Solhjoo, Ting Liu, Brian O’Rourke
J Biol Chem. 2023 Jun; 299(6): 104708. Published online 2023 Apr 14. doi: 10.1016/j.jbc.2023.104708
PMCID:
PMC10206190
AbstractArticlePDF–4.8M
9.
MicroRNA‐155‐5p in serum derived‐exosomes promotes ischaemia–reperfusion injury by reducing CypD ubiquitination by NEDD4
Chenkai Hu, Junyu Liao, Ruiyan Huang, Qiang Su, Lei He
ESC Heart Fail. 2023 Apr; 10(2): 1144–1157. Published online 2023 Jan 11. doi: 10.1002/ehf2.14279
PMCID:
PMC10053265
AbstractArticlePDF–2.3M
10.
Genetic Inhibition of Mitochondrial Permeability Transition Pore Exacerbates Ryanodine Receptor 2 Dysfunction in Arrhythmic Disease
Arpita Deb, Brian D. Tow, You Qing, Madelyn Walker, Emmanuel R. Hodges, James A. Stewart, Jr., Björn C. Knollmann, Yi Zheng, Ying Wang, Bin Liu
Cells. 2023 Jan; 12(2): 204. Published online 2023 Jan 4. doi: 10.3390/cells12020204
PMCID:
PMC9856515
AbstractArticlePDF–3.8M
11.
SR-Mitochondria Crosstalk Shapes Ca Signalling to Impact Pathophenotype in Disease Models Marked by Dysregulated Intracellular Ca Release
Brian D Tow, Arpita Deb, Shraddha Neupane, Shuchi M Patel, Meagan Reed, Anna-Beth Loper, Roman A Eliseev, Björn C Knollmann, Sándor Györke, Bin Liu
Cardiovasc Res. 2022 Sep; 118(13): 2819–2832. Published online 2021 Oct 22. doi: 10.1093/cvr/cvab324
PMCID:
PMC9724772
AbstractArticlePDF–1.3M
12.
Cyclophilin D-induced mitochondrial impairment confers axonal injury after intracerebral hemorrhage in mice
Yang Yang, Kai-Yuan Zhang, Xue-Zhu Chen, Chuan-Yan Yang, Ju Wang, Xue-Jiao Lei, Yu-Lian Quan, Wei-Xiang Chen, Heng-Li Zhao, Li-Kun Yang, Yu-Hai Wang, Yu-Jie Chen, Hua Feng
Neural Regen Res. 2023 Apr; 18(4): 849–855. Published online 2022 Sep 16. doi: 10.4103/1673-5374.353495
PMCID:
PMC9700082
AbstractArticlePDF–5.5M
13.
Remodeling of Liver and Plasma Lipidomes in Mice Lacking Cyclophilin D
Balazs Koszegi, Gabor Balogh, Zoltan Berente, Anett Vranesics, Edit Pollak, Laszlo Molnar, Aniko Takatsy, Viktoria Poor, Matyas Wahr, Csenge Antus, Krisztian Eros, Laszlo Vigh, Ferenc Gallyas, Jr., Maria Peter, Balazs Veres
Int J Mol Sci. 2022 Oct; 23(19): 11274. Published online 2022 Sep 24. doi: 10.3390/ijms231911274
PMCID:
PMC9569465
AbstractArticlePDF–2.1M
14.
SIRT3-Mediated CypD-K166 Deacetylation Alleviates Neuropathic Pain by Improving Mitochondrial Dysfunction and Inhibiting Oxidative Stress
Binbin Yan, Qiang Liu, Xiaobao Ding, Yuwen Lin, Xiaowei Jiao, Yuqing Wu, Huihui Miao, Chenghua Zhou
Oxid Med Cell Longev. 2022; 2022: 4722647. Published online 2022 Sep 1. doi: 10.1155/2022/4722647
PMCID:
PMC9458368
AbstractArticlePDF–3.0M
15.
The effect of Cyclophilin D depletion on liver regeneration following associating liver partition and portal vein ligation for staged hepatectomy
Noemi Daradics, Gergo Horvath, Laszlo Tretter, Agnes Paal, Andras Fulop, Andras Budai, Attila Szijarto
PLoS One. 2022; 17(7): e0271606. Published online 2022 Jul 14. doi: 10.1371/journal.pone.0271606
PMCID:
PMC9282546
AbstractArticlePDF–2.2M
16.
Transcriptional regulation of cyclophilin D by BMP/Smad signaling and its role in osteogenic differentiation
Rubens Sautchuk, Brianna H Kalicharan, Katherine Escalera-Rivera, Jennifer H Jonason, George A Porter, Hani A Awad, Roman A Eliseev
eLife. 2022; 11: e75023. Published online 2022 May 30. doi: 10.7554/eLife.75023
PMCID:
PMC9191891
AbstractArticlePDF–7.2M
17.
Enhanced NCLX-dependent mitochondrial Ca2+ efflux attenuates pathological remodeling in heart failure
Joanne F. Garbincius, Timothy S. Luongo, Pooja Jadiya, Alycia N. Hildebrand, Devin W. Kolmetzky, Adam S. Mangold, Rajika Roy, Jessica Ibetti, Mary Nwokedi, Walter J. Koch, John W. Elrod
J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Jun 1.
Published in final edited form as: J Mol Cell Cardiol. 2022 Jun; 167: 52–66. Published online 2022 Mar 28. doi: 10.1016/j.yjmcc.2022.03.001
PMCID:
PMC9107512
AbstractArticlePDF–2.5M
18.
Uncontrolled mitochondrial calcium uptake underlies the pathogenesis of neurodegeneration in MICU1-deficient mice and patients
Raghavendra Singh, Adam Bartok, Melanie Paillard, Ashley Tyburski, Melanie Elliott, György Hajnóczky
Sci Adv. 2022 Mar; 8(11): eabj4716. Published online 2022 Mar 18. doi: 10.1126/sciadv.abj4716
PMCID:
PMC8932652
AbstractArticlePDF–5.1M
19.
Genetic deletion of p66shc and/or cyclophilin D results in decreased pulmonary vascular tone
Mareike Gierhardt, Oleg Pak, Akylbek Sydykov, Simone Kraut, Julia Schäffer, Claudia Garcia, Christine Veith, Esraa M Zeidan, Monika Brosien, Karin Quanz, Azadeh Esfandiary, Alireza Saraji, Stefan Hadzic, Baktybek Kojonazarov, Jochen Wilhelm, Hossein A Ghofrani, Ralph T Schermuly, Werner Seeger, Friedrich Grimminger, Christiane Herden, Rainer Schulz, Norbert Weissmann, Jacqueline Heger, Natascha Sommer
Cardiovasc Res. 2022 Jan; 118(1): 305–315. Published online 2020 Oct 29. doi: 10.1093/cvr/cvaa310
PMCID:
PMC8752355
AbstractArticlePDF–941K
20.
Inhibition of the Anti-Apoptotic Bcl-2 Family by BH3 Mimetics Sensitize the Mitochondrial Permeability Transition Pore Through Bax and Bak
Pooja Patel, Arielys Mendoza, Dexter J. Robichaux, Meng C. Wang, Xander H. T. Wehrens, Jason Karch
Front Cell Dev Biol. 2021; 9: 765973. Published online 2021 Dec 1. doi: 10.3389/fcell.2021.765973
PMCID:
PMC8672142
AbstractArticlePDF–2.3M

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