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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 102682402.

ZBTB20 is essential for cochlear maturation and hearing in mice

Zhifang Xie, Xian-Hua Ma, Qiu-Fang Bai, Jie Tang, Jian-He Sun, Fei Jiang, Wei Guo, Chen-Ma Wang, Rui Yang, Yin-Chuan Wen, Fang-Yuan Wang, Yu-Xia Chen, Hai Zhang, David Z. He, Matthew W. Kelley, Shiming Yang, Weiping J. Zhang

Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2220867120. Published online 2023 Jun 6. doi: 10.1073/pnas.2220867120

PMCID:: PMC10268240

Abstract Article PDF–7.7M

Select item 102200353.

TRABID inhibition activates cGAS/STING-mediated anti-tumor immunity through mitosis and autophagy dysregulation

Yu-Hsuan Chen, Han-Hsiun Chen, Won-Jing Wang, Hsin-Yi Chen, Wei-Syun Huang, Chien-Han Kao, Sin-Rong Lee, Nai Yang Yeat, Ruei-Liang Yan, Shu-Jou Chan, Kuen-Phon Wu, Ruey-Hwa Chen

Nat Commun. 2023; 14: 3050. Published online 2023 May 26. doi: 10.1038/s41467-023-38784-z

PMCID:: PMC10220035

Abstract Article PDF–3.7M

Select item 102022594.

Runx1 Controls Auditory Sensory Neuron Diversity in Mice

Brikha R Shrestha, Lorna Wu, Lisa V Goodrich

Dev Cell. Author manuscript; available in PMC 2024 Feb 27.

Published in final edited form as: Dev Cell. 2023 Feb 27; 58(4): 306–319.e5. Published online 2023 Feb 16. doi: 10.1016/j.devcel.2023.01.008

PMCID:: PMC10202259

Abstract Article PDF–2.9M

Select item 98129105.

Cochlear hair cell innervation is dependent on a modulatory function of Semaphorin-3A

Homero L. Cantu-Guerra, Michael R. Papazian, Anna L. Gorsky, Nathalie S. Alekos, Adam Caccavano, Nare Karagulyan, Jakob Neef, Stefano Vicini, Tobias Moser, Thomas M. Coate

Dev Dyn. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: Dev Dyn. 2023 Jan; 252(1): 124–144. Published online 2022 Nov 4. doi: 10.1002/dvdy.548

PMCID:: PMC9812910

Abstract Article PDF–5.3M

Select item 98033606.

Tbx2 is a master regulator of inner versus outer hair cell differentiation

Jaime García-Añoveros, John C. Clancy, Chuan Zhi Foo, Ignacio García-Gómez, Yingjie Zhou, Kazuaki Homma, Mary Ann Cheatham, Anne Duggan

Nature. Author manuscript; available in PMC 2022 Dec 30.

Published in final edited form as: Nature. 2022 May; 605(7909): 298–303. Published online 2022 May 4. doi: 10.1038/s41586-022-04668-3

PMCID:: PMC9803360

Abstract Article PDF–4.3M

Select item 96038607.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 94819338.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 94786509.

ISL1 is necessary for auditory neuron development and contributes toward tonotopic organization

Iva Filova, Kateryna Pysanenko, Mitra Tavakoli, Simona Vochyanova, Martina Dvorakova, Romana Bohuslavova, Ondrej Smolik, Valeria Fabriciova, Petra Hrabalova, Sarka Benesova, Lukas Valihrach, Jiri Cerny, Ebenezer N. Yamoah, Josef Syka, Bernd Fritzsch, Gabriela Pavlinkova

Proc Natl Acad Sci U S A. 2022 Sep 13; 119(37): e2207433119. Published online 2022 Sep 8. doi: 10.1073/pnas.2207433119

PMCID:: PMC9478650

Abstract Article PDF–3.6M

Select item 924570610.

Mutations in MINAR2 encoding membrane integral NOTCH2-associated receptor 2 cause deafness in humans and mice

Guney Bademci, María Lachgar-Ruiz, Mangesh Deokar, Mohammad Faraz Zafeer, Clemer Abad, Muzeyyen Yildirim Baylan, Neil J. Ingham, Jing Chen, Claire J. Sineni, Nirmal Vadgama, Ioannis Karakikes, Shengru Guo, Duygu Duman, Nitu Singh, Gaurav Harlalka, Shirish P. Jain, Barry A. Chioza, Katherina Walz, Karen P. Steel, Jamal Nasir, Mustafa Tekin

Proc Natl Acad Sci U S A. 2022 Jun 28; 119(26): e2204084119. Published online 2022 Jun 21. doi: 10.1073/pnas.2204084119

PMCID:: PMC9245706

Abstract Article PDF–3.5M

Select item 922373211.

Eliminating Synaptic Ribbons from Rods and Cones Halves the Releasable Vesicle Pool and Slows Down Replenishment

Chris S. Mesnard, Cody L. Barta, Asia L. Sladek, David Zenisek, Wallace B. Thoreson

Int J Mol Sci. 2022 Jun; 23(12): 6429. Published online 2022 Jun 8. doi: 10.3390/ijms23126429

Correction in:: Int J Mol Sci. 2023 Jan; 24(2): 1561.

PMCID:: PMC9223732

Abstract Article PDF–5.6M

Select item 899311912.

Mutation of SLC7A14 causes auditory neuropathy and retinitis pigmentosa mediated by lysosomal dysfunction

Kimberlee P. Giffen, Yi Li, Huizhan Liu, Xiao-Chang Zhao, Chang-Jun Zhang, Ren-Juan Shen, Tianying Wang, Amanda Janesick, Bo-Bei Chen, Shu-Sheng Gong, Bechara Kachar, Zi-Bing Jin, David Z. He

Sci Adv. 2022 Apr; 8(14): eabk0942. Published online 2022 Apr 8. doi: 10.1126/sciadv.abk0942

PMCID:: PMC8993119

Abstract Article PDF–6.6M

Select item 883169713.

RIBEYE B-Domain Is Essential for RIBEYE A-Domain Stability and Assembly of Synaptic Ribbons

Soni Shankhwar, Karin Schwarz, Rashmi Katiyar, Martin Jung, Stephan Maxeiner, Thomas C. Südhof, Frank Schmitz

Front Mol Neurosci. 2022; 15: 838311. Published online 2022 Jan 28. doi: 10.3389/fnmol.2022.838311

PMCID:: PMC8831697

Abstract Article PDF–18M

Select item 876331714.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

Abstract Article

Select item 859494115.

The mammalian rod synaptic ribbon is essential for Ca_v channel facilitation and ultrafast synaptic vesicle fusion

Chad Paul Grabner, Tobias Moser

eLife. 2021; 10: e63844. Published online 2021 Oct 7. doi: 10.7554/eLife.63844

PMCID:: PMC8594941

Abstract Article PDF–5.3M

Select item 856650516.

The chromatin remodelling factor Chd7 protects auditory neurons and sensory hair cells from stress-induced degeneration

Mohi Ahmed, Ruth Moon, Ravindra Singh Prajapati, Elysia James, M. Albert Basson, Andrea Streit

Commun Biol. 2021; 4: 1260. Published online 2021 Nov 3. doi: 10.1038/s42003-021-02788-6

PMCID:: PMC8566505

Abstract Article PDF–7.8M

Select item 856373317.

The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis

Motohiro Sekiya, Kenta Kainoh, Takehito Sugasawa, Ryunosuke Yoshino, Takatsugu Hirokawa, Hiroaki Tokiwa, Shogo Nakano, Satoru Nagatoishi, Kouhei Tsumoto, Yoshinori Takeuchi, Takafumi Miyamoto, Takashi Matsuzaka, Hitoshi Shimano

Nat Commun. 2021; 12: 6315. Published online 2021 Nov 2. doi: 10.1038/s41467-021-26638-5

PMCID:: PMC8563733

Abstract Article PDF–3.5M

Select item 834871518.

Photoreceptor Compartment-Specific TULP1 Interactomes

Lindsey A. Ebke, Satyabrata Sinha, Gayle J. T. Pauer, Stephanie A. Hagstrom

Int J Mol Sci. 2021 Aug; 22(15): 8066. Published online 2021 Jul 28. doi: 10.3390/ijms22158066

PMCID:: PMC8348715

Abstract Article PDF–3.5M

Select item 831323919.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 794896420.

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1

Lee D. Harris, Janic Le Pen, Nico Scholz, Juliusz Mieszczanek, Natalie Vaughan, Simon Davis, Georgina Berridge, Benedikt M. Kessler, Mariann Bienz, Julien D.F. Licchesi

J Biol Chem. 2021 Jan-Jun; 296: 100246. Published online 2021 Jan 8. doi: 10.1074/jbc.RA120.015162

PMCID:: PMC7948964

Abstract Article PDF–2.7M

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