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Select item 111278071.

Role of Ubiquitin-conjugating enzyme E2 (UBE2) in two immune-mediated inflammatory skin diseases: a mendelian randomization analysis

Xiaoxue Wang, Zexin Zhu

Arch Dermatol Res. 2024; 316(6): 249. Published online 2024 May 25. doi: 10.1007/s00403-024-02976-4

PMCID:: PMC11127807

Abstract Article PDF–1.9M

Select item 105879832.

UBE2V2 promotes metastasis by regulating EMT and predicts a poor prognosis in lung adenocarcinoma

Zheng Yang, Gujie Wu, Jianmei Zhao, Guanglin Shi, Juan Zhou, Xiaoyu Zhou

Cancer Med. 2023 Oct; 12(19): 19850–19865. Published online 2023 Sep 27. doi: 10.1002/cam4.6566

PMCID:: PMC10587983

Abstract Article PDF–12M

Select item 105420253.

Hypoxia-induced long non-coding RNA LINC00460 promotes p53 mediated proliferation and metastasis of pancreatic cancer by regulating the miR-4689/UBE2V1 axis and sequestering USP10

Ronghao Zhang, Xinjing Wang, Xiayang Ying, Yishu Huang, Shuyu Zhai, Minmin Shi, Xiaomei Tang, Jia Liu, Yusheng Shi, Fanlu Li, Weishen Wang, Xiaxing Deng

Int J Med Sci. 2023; 20(10): 1339–1357. Published online 2023 Sep 4. doi: 10.7150/ijms.87833

PMCID:: PMC10542025

Abstract Article PDF–10M

Select item 104356674.

TRIM21-dependent target protein ubiquitination mediates cell-free Trim-Away

Tycho E.T. Mevissen, Anisa V. Prasad, Johannes C. Walter

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112125. Published online 2023 Feb 18. doi: 10.1016/j.celrep.2023.112125

PMCID:: PMC10435667

Abstract Article PDF–2.3M

Select item 102374225.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101516156.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 98832617.

Phosphorylation of OTUB1 at Tyr 26 stabilizes the mTORC1 component, Raptor

Seung Un Seo, Seon Min Woo, Min Wook Kim, Eun-Woo Lee, Kyoung-jin Min, Taeg Kyu Kwon

Cell Death Differ. 2023 Jan; 30(1): 82–93. Published online 2022 Aug 4. doi: 10.1038/s41418-022-01047-3

PMCID:: PMC9883261

Abstract Article PDF–4.6M

Select item 97725588.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 95073579.

Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer

Xiujuan Zhang, Fei Luo, Shaliu Luo, Ling Li, Xinxin Ren, Jing Lin, Yingchun Liang, Chao Ma, Lihua Ding, Deyu Zhang, Tianxing Ye, Yanni Lin, Bilian Jin, Shan Gao, Qinong Ye

Adv Sci (Weinh) 2022 Sep; 9(27): 2200705. Published online 2022 Jul 27. doi: 10.1002/advs.202200705

PMCID:: PMC9507357

Abstract Article PDF–4.1M

Select item 950143810.

Unveiling the Essential Role of Arkadia’s Non-RING Elements in the Ubiquitination Process

Maria Birkou, Georgia N. Delegkou, Konstantinos D. Marousis, Nefeli Fragkaki, Tamara Toro, Vasso Episkopou, Georgios A. Spyroulias

Int J Mol Sci. 2022 Sep; 23(18): 10585. Published online 2022 Sep 13. doi: 10.3390/ijms231810585

PMCID:: PMC9501438

Abstract Article PDF–8.7M

Select item 927928511.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 917141112.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 910272613.

VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway

Zhangya Pu, Dan G. Duda, Yuanyuan Zhu, Siya Pei, Xiaofang Wang, Yan Huang, Panpan Yi, Zebing Huang, Fang Peng, Xingwang Hu, Xuegong Fan

J Transl Med. 2022; 20: 212. Published online 2022 May 13. doi: 10.1186/s12967-022-03416-5

PMCID:: PMC9102726

Abstract Article PDF–15M

Select item 907613314.

Comprehensive Target Screening and Cellular Profiling of the Cancer-Active Compound b-AP15 Indicate Abrogation of Protein Homeostasis and Organelle Dysfunction as the Primary Mechanism of Action

Johannes Gubat, Karthik Selvaraju, Linda Sjöstrand, Dhananjay Kumar Singh, Maria V. Turkina, Bernhard Schmierer, Pierre Sabatier, Roman A. Zubarev, Stig Linder, Pádraig D’Arcy

Front Oncol. 2022; 12: 852980. Published online 2022 Apr 22. doi: 10.3389/fonc.2022.852980

PMCID:: PMC9076133

Abstract Article PDF–6.6M

Select item 902051715.

Structural and functional consequences of NEDD8 phosphorylation

Katrin Stuber, Tobias Schneider, Jill Werner, Michael Kovermann, Andreas Marx, Martin Scheffner

Nat Commun. 2021; 12: 5939. Published online 2021 Oct 12. doi: 10.1038/s41467-021-26189-9

PMCID:: PMC9020517

Abstract Article PDF–2.8M

Select item 899124716.

TMEM189 negatively regulates the stability of ULK1 protein and cell autophagy

Jiahong Yu, Liujing Qu, Yan Xia, Xuan Zhang, Jinqiu Feng, Mengyuan Duan, Pengli guo, Yaxin Lou, Ping Lv, Wenping Lu, Yingyu Chen

Cell Death Dis. 2022 Apr; 13(4): 316. Published online 2022 Apr 7. doi: 10.1038/s41419-022-04722-y

PMCID:: PMC8991247

Abstract Article PDF–3.3M

Select item 895155617.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 856647318.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 843194519.

Uev1A promotes breast cancer cell migration by up-regulating CT45A expression via the AKT pathway

Tong Niu, Zhaojia Wu, Wei Xiao

BMC Cancer. 2021; 21: 1012. Published online 2021 Sep 9. doi: 10.1186/s12885-021-08750-3

PMCID:: PMC8431945

Abstract Article PDF–2.0M

Select item 835296420.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y