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Items: 1 to 20 of 58

1.
Lysophosphatidic acid receptor 1 inhibition: a potential treatment target for pulmonary fibrosis
Elizabeth R. Volkmann, Christopher P. Denton, Martin Kolb, Marlies S. Wijsenbeek-Lourens, Claire Emson, Krischan Hudson, Anthony J. Amatucci, Oliver Distler, Yannick Allanore, Dinesh Khanna
Eur Respir Rev. 2024 Apr 30; 33(172): 240015. Published online 2024 Jun 12. doi: 10.1183/16000617.0015-2024
PMCID:
PMC11262619
AbstractArticlePDF–814K
2.
CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake
Savvas Nikolaou, Amelie Juin, Jamie A Whitelaw, Nikki R Paul, Loic Fort, Colin Nixon, Heather J Spence, Sheila Bryson, Laura M Machesky
eLife. 2024; 13: e83712. Published online 2024 May 7. doi: 10.7554/eLife.83712
PMCID:
PMC11219039
AbstractArticlePDF–14M
3.
Lysophosphatidic acid stimulates the proliferation and motility of malignant pleural mesothelioma cells through lysophosphatidic acid receptors, LPA1 and LPA2
Tadaaki Yamada, Seiji Yano, Hirokazu Ogino, Kenji Ikuta, Soji Kakiuchi, Masaki Hanibuchi, Takanori Kanematsu, Tetsuo Taniguchi, Yoshitaka Sekido, Saburo Sone
Cancer Sci. 2008 Aug; 99(8): 1603–1610. Published online 2008 Aug 14. doi: 10.1111/j.1349-7006.2008.00848.x
PMCID:
PMC11158356
AbstractArticlePDF–383K
4.
LPA1-mediated inhibition of CXCR4 attenuates CXCL12-induced signaling and cell migration
Jong Min Hong, Jin-Woo Lee, Dong-Seung Seen, Jae-Yeon Jeong, Won-Ki Huh
Cell Commun Signal. 2023; 21: 257. Published online 2023 Sep 25. doi: 10.1186/s12964-023-01261-7
PMCID:
PMC10518940
AbstractArticlePDF–2.7M
5.
LPAR1 and aberrantly expressed LPAR3 differentially promote the migration and proliferation of malignant peripheral nerve sheath tumor cells
SHANNON WEBER DOUTT, JODY FROMM LONGO, STEVEN L. CARROLL
Glia. Author manuscript; available in PMC 2024 Mar 1.
Published in final edited form as: Glia. 2023 Mar; 71(3): 742–757. Published online 2022 Nov 23. doi: 10.1002/glia.24308
PMCID:
PMC9868101
AbstractArticlePDF–2.9M
6.
A blocking peptide stabilizes lysophosphatidic acid receptor 1 and promotes lysophosphatidic acid-induced cellular responses
Sarah J Taleb, Jianxin Wei, Rachel K Mialki, Su Dong, Yanhui Li, Jing Zhao, Yutong Zhao
J Cell Biochem. Author manuscript; available in PMC 2022 Mar 19.
Published in final edited form as: J Cell Biochem. 2021 Aug; 122(8): 827–834. Published online 2021 Apr 13. doi: 10.1002/jcb.29919
PMCID:
PMC8934197
AbstractArticlePDF–646K
7.
LPAR1 regulates enteric nervous system function through glial signaling and contributes to chronic intestinal pseudo-obstruction
Mohammad M. Ahmadzai, Jonathon L. McClain, Christine Dharshika, Luisa Seguella, Fiorella Giancola, Roberto De Giorgio, Brian D. Gulbransen
J Clin Invest. 2022 Feb 15; 132(4): e149464. Published online 2022 Feb 15. doi: 10.1172/JCI149464
PMCID:
PMC8843750
AbstractArticlePDF–3.6M
8.
Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate
Shian Liu, Navid Paknejad, Lan Zhu, Yasuyuki Kihara, Manisha Ray, Jerold Chun, Wei Liu, Richard K. Hite, Xin-Yun Huang
Nat Commun. 2022; 13: 731. Published online 2022 Feb 8. doi: 10.1038/s41467-022-28417-2
PMCID:
PMC8826421
AbstractArticlePDF–2.9M
9.
Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance
Jianglan Liu, Vito W. Rebecca, Andrew V. Kossenkov, Thomas Connelly, Qin Liu, Alexis Gutierrez, Min Xiao, Ling Li, Gao Zhang, Anastasia Samarkina, Delaine Zayasbazan, Jie Zhang, Chaoran Cheng, Zhi Wei, Gretchen M. Alicea, Mizuho Fukunaga-Kalabis, Clemens Krepler, Pedro Aza-Blanc, Chih-Cheng Yang, Bela Delvadia, Cynthia Tong, Ye Huang, Maya Delvadia, Alice S. Morias, Katrin Sproesser, Patricia Brafford, Joshua X. Wang, Marilda Beqiri, Rajasekharan Somasundaram, Adina Vultur, Denitsa M. Hristova, Lawrence W. Wu, Yiling Lu, Gordon B. Mills, Wei Xu, Giorgos C. Karakousis, Xiaowei Xu, Lynn M. Schuchter, Tara C. Mitchell, Ravi K. Amaravadi, Lawrence N. Kwong, Dennie T. Frederick, Genevieve M. Boland, Joseph M. Salvino, David W. Speicher, Keith T. Flaherty, Ze'ev A. Ronai, Meenhard Herlyn
Cancer Res. 2021 Oct 15; 81(20): 5230–5241. Published online 2021 Aug 30. doi: 10.1158/0008-5472.CAN-20-1496
PMCID:
PMC8530965
AbstractArticlePDF–14M
10.
Platelet-derived lysophosphatidic acid mediated LPAR1 activation as a therapeutic target for osteosarcoma metastasis
Satoshi Takagi, Yuki Sasaki, Sumie Koike, Ai Takemoto, Yosuke Seto, Mizuki Haraguchi, Takao Ukaji, Tokuichi Kawaguchi, Minoru Sugawara, Masanori Saito, Yuki Funauchi, Keisuke Ae, Seiichi Matsumoto, Naoya Fujita, Ryohei Katayama
Oncogene. 2021; 40(36): 5548–5558. Published online 2021 Jul 23. doi: 10.1038/s41388-021-01956-6
PMCID:
PMC8429042
AbstractArticlePDF–4.2M
11.
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins
Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer
Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490
PMCID:
PMC8266617
AbstractArticlePDF–4.0M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
LPA1 Receptor Promotes Progesterone Receptor Phosphorylation through PKCα in Human Glioblastoma Cells
Silvia Anahi Valdés-Rives, Denisse Arcos-Montoya, Marisol de la Fuente-Granada, Carmen J. Zamora-Sánchez, Luis Enrique Arias-Romero, Olga Villamar-Cruz, Ignacio Camacho-Arroyo, Sonia M. Pérez-Tapia, Aliesha González-Arenas
Cells. 2021 Apr; 10(4): 807. Published online 2021 Apr 4. doi: 10.3390/cells10040807
PMCID:
PMC8066126
AbstractArticlePDF–3.1M
14.
CD97 amplifies LPA receptor signaling and promotes thyroid cancer progression in a mouse model
Y Ward, R Lake, PL Martin, K Killian, P Salerno, T Wang, P Meltzer, M Merino, S-y Cheng, M Santoro, G Garcia-Rostan, K Kelly
Oncogene. Author manuscript; available in PMC 2020 Oct 15.
Published in final edited form as: Oncogene. 2013 May 30; 32(22): 2726–2738. Published online 2012 Jul 16. doi: 10.1038/onc.2012.301
PMCID:
PMC7561260
AbstractArticlePDF–4.8M
15.
Akt regulates a Rab11-effector switch required for ciliogenesis
Vijay Walia, Adrian Cuenca, Melanie Vetter, Christine Insinna, Sumeth Perera, Quanlong Lu, Daniel A. Ritt, Elizabeth Semler, Suzanne Specht, Jimmy Stauffer, Deborah K. Morrison, Esben Lorentzen, Christopher J. Westlake
Dev Cell. Author manuscript; available in PMC 2020 Aug 31.
Published in final edited form as: Dev Cell. 2019 Jul 22; 50(2): 229–246.e7. Published online 2019 Jun 13. doi: 10.1016/j.devcel.2019.05.022
PMCID:
PMC7457226
AbstractArticlePDF–1.8M
16.
The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages
Dapeng Zhang, Rongchen Shi, Wei Xiang, Xia Kang, Bo Tang, Chuan Li, Linfeng Gao, Xuan Zhang, Lili Zhang, Rongyang Dai, Hongming Miao
Signal Transduct Target Ther. 2020; 5: 24. Published online 2020 Mar 27. doi: 10.1038/s41392-020-0117-y
PMCID:
PMC7099097
AbstractArticlePDF–6.3M
17.
Long noncoding RNA ZFAS1 promotes tumorigenesis and metastasis in nasopharyngeal carcinoma by sponging miR‐892b to up‐regulate LPAR1 expression
Jiaojiao Peng, Feng Liu, Hong Zheng, Qi Wu, Shixi Liu
J Cell Mol Med. 2020 Jan; 24(2): 1437–1450. Published online 2019 Dec 18. doi: 10.1111/jcmm.14823
PMCID:
PMC6991699
AbstractArticlePDF–2.0M
18.
LPA receptor heterodimerizes with CD97 to amplify LPA initiated Rho-dependent signaling and invasion in prostate cancer cells
Yvona Ward, Ross Lake, Juan Juan Yin, Christopher D. Heger, Mark Raffeld, Paul K. Goldsmith, Maria Merino, Kathleen Kelly
Cancer Res. Author manuscript; available in PMC 2019 Aug 15.
Published in final edited form as: Cancer Res. 2011 Dec 1; 71(23): 7301–7311. Published online 2011 Oct 6. doi: 10.1158/0008-5472.CAN-11-2381
PMCID:
PMC6697138
AbstractArticlePDF–2.0M
19.
ADSCs and adipocytes are the main producers in the autotaxin–lysophosphatidic acid axis of breast cancer and healthy mammary tissue in vitro
Rafael Schmid, Katharina Wolf, Jan W. Robering, Selina Strauß, Pamela L. Strissel, Reiner Strick, Matthias Rübner, Peter A. Fasching, Raymund E. Horch, Andreas E. Kremer, Anja M. Boos, Annika Weigand
BMC Cancer. 2018; 18: 1273. Published online 2018 Dec 19. doi: 10.1186/s12885-018-5166-z
PMCID:
PMC6300006
AbstractArticlePDF–1.0M
20.
Lysophosphatidic acid acts on LPA1 receptor to increase H2O2 during flow‐induced dilation in human adipose arterioles
Dawid S Chabowski, Andrew O Kadlec, Karima Ait‐Aissa, Joseph C Hockenberry, Paul J Pearson, Andreas M Beyer, David D Gutterman
Br J Pharmacol. 2018 Nov; 175(22): 4266–4280. Published online 2018 Oct 11. doi: 10.1111/bph.14492
PMCID:
PMC6193883
AbstractArticlePDF–860K

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