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Select item 81650301.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81287922.

Correlation between serum carnosinase concentration and renal damage in diabetic nephropathy patients

Zhou Zhou, Xue-qi Liu, Shi-qi Zhang, Xiang-ming Qi, Qiu Zhang, Benito Yard, Yong-gui Wu

Amino Acids. 2021; 53(5): 687–700. Published online 2021 Apr 3. doi: 10.1007/s00726-021-02975-z

PMCID:: PMC8128792

Abstract Article PDF–13M

Select item 74476803.

Human carnosinase 1 overexpression aggravates diabetes and renal impairment in BTBR^Ob/Ob mice

Jiedong Qiu, Thomas Albrecht, Shiqi Zhang, Sibylle J. Hauske, Angelica Rodriguez-Niño, Xinmiao Zhang, Darya Nosan, Diego O. Pastene, Carsten Sticht, Carolina Delatorre, Harry van Goor, Stefan Porubsky, Bernhard K. Krämer, Benito A. Yard

J Mol Med (Berl) 2020; 98(9): 1333–1346. Published online 2020 Aug 15. doi: 10.1007/s00109-020-01957-0

PMCID:: PMC7447680

Abstract Article PDF–2.3M

Select item 73833294.

Genotype Distribution of CNDP1 Polymorphisms in the Healthy Chinese Han Population: Association with HbA1c and Fasting Blood Glucose

Shiqi Zhang, Juan Xu, Di Cui, Shujuan Jiang, Xin Xu, Yi Zhang, Dongchun Zhu, Li Xia, Benito Yard, Yonggui Wu, Qiu Zhang

J Diabetes Res. 2020; 2020: 3838505. Published online 2020 Jul 18. doi: 10.1155/2020/3838505

PMCID:: PMC7383329

Abstract Article PDF–444K

Select item 62712925.

Carnosinases, Their Substrates and Diseases

Francesco Bellia, Graziella Vecchio, Enrico Rizzarelli

Molecules. 2014 Feb; 19(2): 2299–2329. Published online 2014 Feb 21. doi: 10.3390/molecules19022299

PMCID:: PMC6271292

Abstract Article PDF–1.6M

Select item 59658726.

Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrP^C) in Alzheimer’s disease

Sarah Ulbrich, Petra Janning, Ralf Seidel, Jakob Matschke, Anika Gonsberg, Sebastian Jung, Markus Glatzel, Martin Engelhard, Konstanze F. Winklhofer, Jörg Tatzelt

PLoS One. 2018; 13(5): e0197659. Published online 2018 May 23. doi: 10.1371/journal.pone.0197659

PMCID:: PMC5965872

Abstract Article PDF–2.4M

Select item 55316117.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 54344688.

The CNDP1 (CTG)₅ Polymorphism Is Associated with Biopsy-Proven Diabetic Nephropathy, Time on Hemodialysis, and Diabetes Duration

Thomas Albrecht, Shiqi Zhang, Jana D. Braun, Li Xia, Angelica Rodriquez, Jiedong Qiu, Verena Peters, Claus P. Schmitt, Jacob van den Born, Stephan J. L. Bakker, Alexander Lammert, Hannes Köppel, Peter Schnuelle, Bernhard K. Krämer, Benito A. Yard, Sibylle J. Hauske

J Diabetes Res. 2017; 2017: 9506730. Published online 2017 May 3. doi: 10.1155/2017/9506730

PMCID:: PMC5434468

Abstract Article PDF–1.3M

Select item 51169009.

The (CTG)_n repeat polymorphism in CNDP1 gene: new insights into an old molecule

Kátia G. Santos

Indian J Med Res. 2016 Jul; 144(1): 6–8. doi: 10.4103/0971-5916.193276

PMCID:: PMC5116900

Article PDF–229K

Select item 511689510.

Association of CTG repeat polymorphism in carnosine dipeptidase 1 (CNDP1) gene with diabetic nephropathy in north Indians

Ashok K. Yadav, Nisha Sinha, Vinod Kumar, Anil Bhansali, Pinaki Dutta, Vivekanand Jha

Indian J Med Res. 2016 Jul; 144(1): 32–37. doi: 10.4103/0971-5916.193280

PMCID:: PMC5116895

Abstract Article PDF–572K

Select item 463344911.

Intrinsic carnosine metabolism in the human kidney

Verena Peters, Celine Q. F. Klessens, Hans J. Baelde, Benjamin Singler, Kimberley A. M. Veraar, Ana Zutinic, Jakub Drozak, Johannes Zschocke, Claus P. Schmitt, Emile de Heer

Amino Acids. 2015; 47(12): 2541–2550. Published online 2015 Jul 24. doi: 10.1007/s00726-015-2045-7

PMCID:: PMC4633449

Abstract Article PDF–933K

Select item 461721112.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 459544213.

Muscle Carnosine Is Associated with Cardiometabolic Risk Factors in Humans

Barbora de Courten, Timea Kurdiova, Maximilian P. J. de Courten, Vitazoslav Belan, Inge Everaert, Marek Vician, Helena Teede, Daniela Gasperikova, Giancarlo Aldini, Wim Derave, Jozef Ukropec, Barbara Ukropcova

PLoS One. 2015; 10(10): e0138707. Published online 2015 Oct 6. doi: 10.1371/journal.pone.0138707

PMCID:: PMC4595442

Abstract Article PDF–779K

Select item 440548714.

Circulating Carnosine Dipeptidase 1 Associates with Weight Loss and Poor Prognosis in Gastrointestinal Cancer

Peter Arner, Frauke Henjes, Jochen M. Schwenk, Spyros Darmanis, Ingrid Dahlman, Britt-Marie Iresjö, Peter Naredi, Thorhallur Agustsson, Kent Lundholm, Peter Nilsson, Mikael Rydén

PLoS One. 2015; 10(4): e0123566. Published online 2015 Apr 21. doi: 10.1371/journal.pone.0123566

PMCID:: PMC4405487

Abstract Article PDF–549K

Select item 409408215.

Metabolite Proofreading in Carnosine and Homocarnosine Synthesis: MOLECULAR IDENTIFICATION OF PM20D2 AS β-ALANYL-LYSINE DIPEPTIDASE

Maria Veiga-da-Cunha, Nathalie Chevalier, Vincent Stroobant, Didier Vertommen, Emile Van Schaftingen

J Biol Chem. 2014 Jul 11; 289(28): 19726–19736. Published online 2014 Jun 2. doi: 10.1074/jbc.M114.576579

PMCID:: PMC4094082

Abstract Article PDF–1.5M

Select item 354696216.

The Influence of a Single Nucleotide Polymorphism within CNDP1 on Susceptibility to Diabetic Nephropathy in Japanese Women with Type 2 Diabetes

Mahiro Kurashige, Minako Imamura, Shin-ichi Araki, Daisuke Suzuki, Tetsuya Babazono, Takashi Uzu, Tomoya Umezono, Masao Toyoda, Koichi Kawai, Masahito Imanishi, Kazushige Hanaoka, Hiroshi Maegawa, Yasuko Uchigata, Tatsuo Hosoya, Shiro Maeda

PLoS One. 2013; 8(1): e54064. Published online 2013 Jan 16. doi: 10.1371/journal.pone.0054064

PMCID:: PMC3546962

Abstract Article PDF–254K

Select item 346102017.

Proteins with Altered Levels in Plasma from Glioblastoma Patients as Revealed by iTRAQ-Based Quantitative Proteomic Analysis

Poonam Gautam, Sudha C. Nair, Manoj Kumar Gupta, Rakesh Sharma, Ravindra Varma Polisetty, Megha S. Uppin, Challa Sundaram, Aneel K. Puligopu, Praveen Ankathi, Aniruddh K. Purohit, Giriraj R. Chandak, H. C. Harsha, Ravi Sirdeshmukh

PLoS One. 2012; 7(9): e46153. Published online 2012 Sep 28. doi: 10.1371/journal.pone.0046153

PMCID:: PMC3461020

Abstract Article PDF–1.3M

Select item 319082618.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907

PMCID:: PMC3190826

Abstract Article PDF–5.7M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 310128320.

Association of variants in the carnosine peptidase 1 gene (CNDP1) with diabetic nephropathy in American Indians

Harini A. Chakkera, Robert L. Hanson, Sayuko Kobes, Meredith P. Millis, Robert G. Nelson, William C. Knowler, Johanna K. DiStefano

Mol Genet Metab. Author manuscript; available in PMC 2012 Jun 1.

Published in final edited form as: Mol Genet Metab. 2011 Jun; 103(2): 185–190. Published online 2011 Feb 19. doi: 10.1016/j.ymgme.2011.02.010

PMCID:: PMC3101283

Abstract Article PDF–333K

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